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Volumn 151, Issue 4, 2007, Pages 427-440

Cannabinoids as therapeutic agents in cardiovascular disease: A tale of passions and illusions

Author keywords

Cannabis; Endocannabinoids; Hypertension; Medical use; Rimonabant; Shock

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; ANANDAMIDE; ANTIHYPERTENSIVE AGENT; CANNABINOID; CANNABINOID 1 RECEPTOR ANTAGONIST; CANNABINOID 2 RECEPTOR AGONIST; CANNABINOID RECEPTOR AGONIST; CANNABINOID RECEPTOR ANTAGONIST; CANNABIS; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; DEXANABINOL; DRONABINOL; ENDOCANNABINOID; METHANANDAMIDE; MORPHINE; N (4 HYDROXYPHENYL)ARACHIDONAMIDE; NABILONE; NITRIC OXIDE; O 1918; OMDM 2; RIMONABANT; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

EID: 34250213868     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707261     Document Type: Review
Times cited : (85)

References (136)
  • 1
    • 0017068782 scopus 로고
    • Tolerance to the cardiovascular effects of delta9-tetrahydrocannabinol in the rat
    • Adams MD, Chait LD, Earnhardt JT (1976). Tolerance to the cardiovascular effects of delta9-tetrahydrocannabinol in the rat. Br J Pharmacol 56: 43-48.
    • (1976) Br J Pharmacol , vol.56 , pp. 43-48
    • Adams, M.D.1    Chait, L.D.2    Earnhardt, J.T.3
  • 2
    • 0016133282 scopus 로고
    • The cannabinoids: Therapeutic potentials
    • Archer RA (1974). The cannabinoids: therapeutic potentials. Annu Rep Med Chem 9: 253-259.
    • (1974) Annu Rep Med Chem , vol.9 , pp. 253-259
    • Archer, R.A.1
  • 3
    • 0034928628 scopus 로고    scopus 로고
    • Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis
    • Bátkai S, Jarai Z, Wagner JA, Goparaju SK, Varga K, Liu J et al. (2001). Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. Nat Med 7: 827-832.
    • (2001) Nat Med , vol.7 , pp. 827-832
    • Bátkai, S.1    Jarai, Z.2    Wagner, J.A.3    Goparaju, S.K.4    Varga, K.5    Liu, J.6
  • 4
    • 17144470921 scopus 로고    scopus 로고
    • Cannabinoid antagonist SR-141716 inhibits endotoxic hypotension by a cardiac mechanism not involving CB1 or CB2 receptors
    • Bátkai S, Pacher P, Jarai Z, Wagner JA, Kunos G (2004a). Cannabinoid antagonist SR-141716 inhibits endotoxic hypotension by a cardiac mechanism not involving CB1 or CB2 receptors. Am J Physiol Heart Circ Physiol 287: H595-H600.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Bátkai, S.1    Pacher, P.2    Jarai, Z.3    Wagner, J.A.4    Kunos, G.5
  • 5
    • 20844454912 scopus 로고    scopus 로고
    • Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension
    • Bátkai S, Pacher P, Osei-Hyiaman D, Radaeva S, Liu J, Harvey-White J et al. (2004b). Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation 110: 1996-2002.
    • (2004) Circulation , vol.110 , pp. 1996-2002
    • Bátkai, S.1    Pacher, P.2    Osei-Hyiaman, D.3    Radaeva, S.4    Liu, J.5    Harvey-White, J.6
  • 7
    • 0030865871 scopus 로고    scopus 로고
    • Functional role of high affinity anandamide transport, as revealed by selective inhibition
    • Beltramo M, Stella N, Calignano A, Lin SY, Makriyannis A, Piomelli D (1997). Functional role of high affinity anandamide transport, as revealed by selective inhibition. Science 277: 1094-1097.
    • (1997) Science , vol.277 , pp. 1094-1097
    • Beltramo, M.1    Stella, N.2    Calignano, A.3    Lin, S.Y.4    Makriyannis, A.5    Piomelli, D.6
  • 8
    • 0016769009 scopus 로고
    • Cardiovascular effects of prolonged delta-9-tetrahydrocannabinol ingestion
    • Benowitz NL, Jones RT (1975). Cardiovascular effects of prolonged delta-9-tetrahydrocannabinol ingestion. Clin Pharmacol Ther 18: 287-297.
    • (1975) Clin Pharmacol Ther , vol.18 , pp. 287-297
    • Benowitz, N.L.1    Jones, R.T.2
  • 9
    • 0019604102 scopus 로고
    • Cardiovascular and metabolic considerations in prolonged cannabinoid administration in man
    • Benowitz NL, Jones RT (1981). Cardiovascular and metabolic considerations in prolonged cannabinoid administration in man. J Clin Pharmacol 21: 214S-223S.
    • (1981) J Clin Pharmacol , vol.21
    • Benowitz, N.L.1    Jones, R.T.2
  • 10
    • 0018384731 scopus 로고
    • Cardiovascular effects of intravenous delta-9-tetrahydrocanabinol: Autonomic nervous mechanisms
    • Benowitz NL, Rosenberg J, Rogers W, Bachman J, Jones RT (1979). Cardiovascular effects of intravenous delta-9-tetrahydrocanabinol: autonomic nervous mechanisms. Clin Pharmacol Ther 25: 440-446.
    • (1979) Clin Pharmacol Ther , vol.25 , pp. 440-446
    • Benowitz, N.L.1    Rosenberg, J.2    Rogers, W.3    Bachman, J.4    Jones, R.T.5
  • 11
  • 12
    • 0031031557 scopus 로고    scopus 로고
    • Biosynthesis, release and degradation of anandamide and palmitoylethanolamide in leukocytes
    • Bisogno T, Maurelli S, Melck D, De Petrocellis L, Di Marzo V (1997). Biosynthesis, release and degradation of anandamide and palmitoylethanolamide in leukocytes. J Biol Chem 272: 3315-3323.
    • (1997) J Biol Chem , vol.272 , pp. 3315-3323
    • Bisogno, T.1    Maurelli, S.2    Melck, D.3    De Petrocellis, L.4    Di Marzo, V.5
  • 13
    • 0034711508 scopus 로고    scopus 로고
    • The late phase of preconditioning
    • Bolli R (2000). The late phase of preconditioning. Circ Res 87: 972-983.
    • (2000) Circ Res , vol.87 , pp. 972-983
    • Bolli, R.1
  • 15
    • 0033575258 scopus 로고    scopus 로고
    • 2 phosphorylation by the inverse agonist SR 144528. Implications for receptor biological responses
    • 2 phosphorylation by the inverse agonist SR 144528. Implications for receptor biological responses. J Biol Chem 274: 20397-20405.
    • (1999) J Biol Chem , vol.274 , pp. 20397-20405
    • Bouaboula, M.1    Dussossoy, D.2    Casellas, P.3
  • 17
    • 0034685707 scopus 로고    scopus 로고
    • Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor
    • Buckley NE, McCoy KL, Mezey E, Bonner T, Zimmer A, Felder CC et al. (2000). Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor. Eur J Pharmacol 396: 141-149.
    • (2000) Eur J Pharmacol , vol.396 , pp. 141-149
    • Buckley, N.E.1    McCoy, K.L.2    Mezey, E.3    Bonner, T.4    Zimmer, A.5    Felder, C.C.6
  • 18
    • 32144447596 scopus 로고    scopus 로고
    • The endocannabinoid system: A new approach to control cardiovascular disease
    • Cannon CP (2005). The endocannabinoid system: a new approach to control cardiovascular disease. Clin Cornerstone 7: 17-26.
    • (2005) Clin Cornerstone , vol.7 , pp. 17-26
    • Cannon, C.P.1
  • 19
    • 0031594723 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor and endothelium-dependent hyperpolarization in guinea-pig carotid, rat mesenteric and porcine coronary arteries
    • Chataigneau T, Feletou M, Thollon C, Villeneuve N, Vilaine JP, Duhault J et al. (1998). Cannabinoid CB1 receptor and endothelium-dependent hyperpolarization in guinea-pig carotid, rat mesenteric and porcine coronary arteries. Br J Pharmacol 123: 968-974.
    • (1998) Br J Pharmacol , vol.123 , pp. 968-974
    • Chataigneau, T.1    Feletou, M.2    Thollon, C.3    Villeneuve, N.4    Vilaine, J.P.5    Duhault, J.6
  • 20
    • 0033569702 scopus 로고    scopus 로고
    • The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication
    • Chaytor AT, Martin PEM, Evans WH, Randall MD, Griffith TM (1999). The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. J Physiol 520: 539-550.
    • (1999) J Physiol , vol.520 , pp. 539-550
    • Chaytor, A.T.1    Martin, P.E.M.2    Evans, W.H.3    Randall, M.D.4    Griffith, T.M.5
  • 21
    • 85047690626 scopus 로고    scopus 로고
    • The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
    • Cota D, Marsicano G, Tschop M, Grubler Y, Flachskamm C, Schubert M et al. (2003). The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 112: 423-431.
    • (2003) J Clin Invest , vol.112 , pp. 423-431
    • Cota, D.1    Marsicano, G.2    Tschop, M.3    Grubler, Y.4    Flachskamm, C.5    Schubert, M.6
  • 22
    • 0042572380 scopus 로고    scopus 로고
    • Fatty acid amide hydrolase: An emerging therapeutic target in the endocannabinoid system
    • Cravatt BF, Lichtman AH (2003). Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system. Curr Opin Chem Biol 7: 469-475.
    • (2003) Curr Opin Chem Biol , vol.7 , pp. 469-475
    • Cravatt, B.F.1    Lichtman, A.H.2
  • 23
    • 4644372326 scopus 로고    scopus 로고
    • The endogenous cannabinoid system and its role in nociceptive behavior
    • Cravatt BF, Lichtman AH (2004). The endogenous cannabinoid system and its role in nociceptive behavior. J Neurobiol 61: 149-160.
    • (2004) J Neurobiol , vol.61 , pp. 149-160
    • Cravatt, B.F.1    Lichtman, A.H.2
  • 25
    • 0027180394 scopus 로고
    • Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist
    • Deutsch DG, Chin SA (1993). Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. Biochem Pharmacol 46: 791-796.
    • (1993) Biochem Pharmacol , vol.46 , pp. 791-796
    • Deutsch, D.G.1    Chin, S.A.2
  • 28
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G et al. (1992). Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258: 1946-1949.
    • (1992) Science , vol.258 , pp. 1946-1949
    • Devane, W.A.1    Hanus, L.2    Breuer, A.3    Pertwee, R.G.4    Stevenson, L.A.5    Griffin, G.6
  • 29
    • 0022509199 scopus 로고
    • Cannabinoid Pharmacology
    • Dewey WL (1986). Cannabinoid Pharmacology. Pharmacol Rev 38: 151-178.
    • (1986) Pharmacol Rev , vol.38 , pp. 151-178
    • Dewey, W.L.1
  • 30
    • 32944482013 scopus 로고    scopus 로고
    • Plant, synthetic, and endogenous cannabinoids in medicine
    • Marzo V, De Petrocellis L (2006). Plant, synthetic, and endogenous cannabinoids in medicine. Annu Rev Med 57: 553-574.
    • (2006) Annu Rev Med , vol.57 , pp. 553-574
    • Marzo, V.1    De Petrocellis, L.2
  • 31
    • 0029756752 scopus 로고    scopus 로고
    • Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells
    • Marzo V, De Petrocellis L, Sepe N, Buono A (1996). Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. Biochem J 316: 977-984.
    • (1996) Biochem J , vol.316 , pp. 977-984
    • Marzo, V.1    De Petrocellis, L.2    Sepe, N.3    Buono, A.4
  • 34
    • 0029558259 scopus 로고
    • Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin
    • Ellis EF, Moore SF, Willoughby KA (1995). Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin. Am J Physiol 269: H1859-H1864.
    • (1995) Am J Physiol , vol.269
    • Ellis, E.F.1    Moore, S.F.2    Willoughby, K.A.3
  • 35
    • 0036193753 scopus 로고    scopus 로고
    • Evidence of a novel site mediating anandamide-induced negative inotropic and coronary vasodilator responses in rat isolated hearts
    • Ford WR, Honan SA, White R, Hiley CR (2002). Evidence of a novel site mediating anandamide-induced negative inotropic and coronary vasodilator responses in rat isolated hearts. Br J Pharmacol 135: 1191-1198.
    • (2002) Br J Pharmacol , vol.135 , pp. 1191-1198
    • Ford, W.R.1    Honan, S.A.2    White, R.3    Hiley, C.R.4
  • 36
    • 0019496897 scopus 로고
    • The cardiovascular and autonomic effects of repeated administration of delta-9-tetrahydrocannabinol to rhesus monkeys
    • Fredericks AB, Benowitz NL, Savanapridi CY (1981). The cardiovascular and autonomic effects of repeated administration of delta-9-tetrahydrocannabinol to rhesus monkeys. J Pharmacol Exp Ther 216: 247-253.
    • (1981) J Pharmacol Exp Ther , vol.216 , pp. 247-253
    • Fredericks, A.B.1    Benowitz, N.L.2    Savanapridi, C.Y.3
  • 37
    • 0032160757 scopus 로고    scopus 로고
    • Evidence against anandamide as the hyperpolarizing factor mediating the nitric oxide-independent coronary vasodilator effect of bradykinin in the rat
    • Fulton D, Quilley J (1998). Evidence against anandamide as the hyperpolarizing factor mediating the nitric oxide-independent coronary vasodilator effect of bradykinin in the rat. J Pharmacol Exp Ther 286: 1146-1151.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1146-1151
    • Fulton, D.1    Quilley, J.2
  • 39
    • 33644559036 scopus 로고    scopus 로고
    • Role of CGRP and GABA in the hypotensive effect of intrathecally administered anandamide to anesthetized rats
    • García MC, Adler-Graschinsky E, Celuch SM (2006). Role of CGRP and GABA in the hypotensive effect of intrathecally administered anandamide to anesthetized rats. Eur J Pharmacol 532: 88-98.
    • (2006) Eur J Pharmacol , vol.532 , pp. 88-98
    • García, M.C.1    Adler-Graschinsky, E.2    Celuch, S.M.3
  • 40
    • 27144472559 scopus 로고    scopus 로고
    • Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats
    • Gaskari SA, Liu H, Moezi L, Li Y, Baik SK, Lee SS (2005). Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats. Br J Pharmacol 146: 315-323.
    • (2005) Br J Pharmacol , vol.146 , pp. 315-323
    • Gaskari, S.A.1    Liu, H.2    Moezi, L.3    Li, Y.4    Baik, S.K.5    Lee, S.S.6
  • 42
    • 33646481040 scopus 로고    scopus 로고
    • Rimonabant: A cannabinoid receptor type 1 blocker for management of multiple cardiometabolic risk factors
    • Gelfand EV, Cannon CP (2006). Rimonabant: a cannabinoid receptor type 1 blocker for management of multiple cardiometabolic risk factors. J Am Coll Cardiol 47: 1919-1926.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 1919-1926
    • Gelfand, E.V.1    Cannon, C.P.2
  • 43
    • 3242786248 scopus 로고    scopus 로고
    • Presynaptic cannabinoid CB(1) receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats
    • Godlewski G, Malinowska B, Schlicker E. (2004). Presynaptic cannabinoid CB(1) receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats. Br J Pharmacol 142: 701-708.
    • (2004) Br J Pharmacol , vol.142 , pp. 701-708
    • Godlewski, G.1    Malinowska, B.2    Schlicker, E.3
  • 44
    • 0035169841 scopus 로고    scopus 로고
    • Anandamide-induced relaxation of sheep coronary arteries: The role of the vascular endothelium, arachidonic acid metabolites and potassium channels
    • Grainger J, Boachie-Ansah G (2001). Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. Br J Pharmacol 134: 1003-1012.
    • (2001) Br J Pharmacol , vol.134 , pp. 1003-1012
    • Grainger, J.1    Boachie-Ansah, G.2
  • 45
    • 0035801320 scopus 로고    scopus 로고
    • Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus
    • Hájos N, Ledent C, Freund TF (2001). Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus. Neuroscience 106: 1-4.
    • (2001) Neuroscience , vol.106 , pp. 1-4
    • Hájos, N.1    Ledent, C.2    Freund, T.F.3
  • 46
    • 0015167059 scopus 로고
    • General pharmacological actions of some synthetic tetrahydrocannabinol derivatives
    • Hardman HF, Domino EF, Seevers MH (1971). General pharmacological actions of some synthetic tetrahydrocannabinol derivatives. Pharmacol Rev 23: 295-315.
    • (1971) Pharmacol Rev , vol.23 , pp. 295-315
    • Hardman, H.F.1    Domino, E.F.2    Seevers, M.H.3
  • 47
    • 0037088843 scopus 로고    scopus 로고
    • Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed
    • Harris D, McCulloch AI, Kendall DA, Randall MD (2002). Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed. J Physiol 539: 893-902.
    • (2002) J Physiol , vol.539 , pp. 893-902
    • Harris, D.1    McCulloch, A.I.2    Kendall, D.A.3    Randall, M.D.4
  • 48
    • 0025954862 scopus 로고
    • Characterization and localization of cannabinoid receptors in rat brain: A quantitative in vitro autoradiographic study
    • Herkenham M, Lynn AB, Johnson MR, Melvin LS, de Costa BR, Rice KC (1991). Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study. J. Neurosci 11: 563-583.
    • (1991) J. Neurosci , vol.11 , pp. 563-583
    • Herkenham, M.1    Lynn, A.B.2    Johnson, M.R.3    Melvin, L.S.4    de Costa, B.R.5    Rice, K.C.6
  • 49
    • 1442315642 scopus 로고    scopus 로고
    • Cannabinoid pharmacology in the cardiovascular system: Potential protective mechanisms through lipid signalling
    • Hiley CR, Ford WR (2004). Cannabinoid pharmacology in the cardiovascular system: potential protective mechanisms through lipid signalling. Biol Rev Camb Philos Soc 79: 187-205.
    • (2004) Biol Rev Camb Philos Soc , vol.79 , pp. 187-205
    • Hiley, C.R.1    Ford, W.R.2
  • 50
    • 0033917648 scopus 로고    scopus 로고
    • Endocannabinoids and vascular function
    • Hillard CJ (2000). Endocannabinoids and vascular function. J Pharmacol Exp Ther 294: 27-32.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 27-32
    • Hillard, C.J.1
  • 52
    • 34250218367 scopus 로고    scopus 로고
    • House of Lords (1998). Science and Technology - Ninth Report. Science and Technology Committee Publications.
    • House of Lords (1998). Science and Technology - Ninth Report. Science and Technology Committee Publications.
  • 53
    • 0041836218 scopus 로고    scopus 로고
    • Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS
    • Ibrahim MM, Deng H, Zvonok A, Cockayne DA, Kwan J, Mata HP et al. (2003). Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS. Proc Natl Acad Sci USA 100: 10529-10533.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10529-10533
    • Ibrahim, M.M.1    Deng, H.2    Zvonok, A.3    Cockayne, D.A.4    Kwan, J.5    Mata, H.P.6
  • 56
    • 0036838392 scopus 로고    scopus 로고
    • Cardiovascular system effects of marijuana
    • Jones RT (2002). Cardiovascular system effects of marijuana. J Clin Pharmacol 42: 58S-63S.
    • (2002) J Clin Pharmacol , vol.42
    • Jones, R.T.1
  • 57
    • 0036023638 scopus 로고    scopus 로고
    • Endocannabinoids are implicated in the infarct size reducing effect conferred by heat stress preconditioning in isolated rat hearts
    • Joyeux M, Arnaud C, Godin-Ribuot D, Demenge P, Lamontagne D, Ribuot C (2002). Endocannabinoids are implicated in the infarct size reducing effect conferred by heat stress preconditioning in isolated rat hearts. Cardiovasc Res 55: 619-625.
    • (2002) Cardiovasc Res , vol.55 , pp. 619-625
    • Joyeux, M.1    Arnaud, C.2    Godin-Ribuot, D.3    Demenge, P.4    Lamontagne, D.5    Ribuot, C.6
  • 58
    • 0034883101 scopus 로고    scopus 로고
    • Medicinal use of cannabis: History and current status
    • Kalant H (2001). Medicinal use of cannabis: history and current status. Pain Res Manag 6: 80-91.
    • (2001) Pain Res Manag , vol.6 , pp. 80-91
    • Kalant, H.1
  • 61
    • 0018197880 scopus 로고
    • Antihypertensive effects of delta9-tetrahydro- cannabinol
    • Kosersky DS (1978). Antihypertensive effects of delta9-tetrahydro- cannabinol. Arch Int Pharmacodyn Ther 233: 76-81.
    • (1978) Arch Int Pharmacodyn Ther , vol.233 , pp. 76-81
    • Kosersky, D.S.1
  • 63
    • 0035120753 scopus 로고    scopus 로고
    • Involvement of cannabinoids in the cardioprotection induced by lipopolysaccharide
    • Lagneux C, Lamontagne D (2001). Involvement of cannabinoids in the cardioprotection induced by lipopolysaccharide. Br J Pharmacol 132: 793-796.
    • (2001) Br J Pharmacol , vol.132 , pp. 793-796
    • Lagneux, C.1    Lamontagne, D.2
  • 64
    • 0030925426 scopus 로고    scopus 로고
    • Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors
    • Lake KD, Compton DR, Varga K, Martin BR, Kunos G (1997). Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. J Pharmacol Exp Ther 281: 1030-1037.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 1030-1037
    • Lake, K.D.1    Compton, D.R.2    Varga, K.3    Martin, B.R.4    Kunos, G.5
  • 66
    • 33646181593 scopus 로고    scopus 로고
    • The endogenous cardiac cannabinoid system: A new protective mechanism against myocardial ischemia
    • Lamontagne D, Lepicier P, Lagneux C, Bouchard JF (2006). The endogenous cardiac cannabinoid system: a new protective mechanism against myocardial ischemia. Arch Mal Coeur Vaiss 99: 242-246.
    • (2006) Arch Mal Coeur Vaiss , vol.99 , pp. 242-246
    • Lamontagne, D.1    Lepicier, P.2    Lagneux, C.3    Bouchard, J.F.4
  • 67
    • 0033555839 scopus 로고    scopus 로고
    • Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
    • Ledent C, Valverde O, Cossu G, Petitet F, Aubert JF, Beslot F et al. (1999). Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 283: 401-404.
    • (1999) Science , vol.283 , pp. 401-404
    • Ledent, C.1    Valverde, O.2    Cossu, G.3    Petitet, F.4    Aubert, J.F.5    Beslot, F.6
  • 68
    • 0038002221 scopus 로고    scopus 로고
    • Endocannabinoids protect the rat isolated heart against ischaemia
    • Lepicier P, Bouchard JF, Lagneux C, Lamontagne D (2003). Endocannabinoids protect the rat isolated heart against ischaemia. Br J Pharmacol 139: 805-815.
    • (2003) Br J Pharmacol , vol.139 , pp. 805-815
    • Lepicier, P.1    Bouchard, J.F.2    Lagneux, C.3    Lamontagne, D.4
  • 69
    • 0037338753 scopus 로고    scopus 로고
    • J, Kaminski NE, Wang DH (2003). Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor. Hypertension 41: 757-762.
    • J, Kaminski NE, Wang DH (2003). Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor. Hypertension 41: 757-762.
  • 70
    • 21544467275 scopus 로고    scopus 로고
    • Pathophysiology of coronary artery disease
    • Libby P, Theroux P (2005). Pathophysiology of coronary artery disease. Circulation 111: 3481-3488.
    • (2005) Circulation , vol.111 , pp. 3481-3488
    • Libby, P.1    Theroux, P.2
  • 72
    • 33144480327 scopus 로고    scopus 로고
    • Cannabinoid receptors as therapeutic targets
    • Mackie K (2006). Cannabinoid receptors as therapeutic targets. Annu Rev Pharmacol Toxicol 46: 101-122.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 101-122
    • Mackie, K.1
  • 73
    • 33646814424 scopus 로고    scopus 로고
    • Cannabinoid receptors and endocannabinoids: Evidence for new players
    • Mackie K, Stella N (2006). Cannabinoid receptors and endocannabinoids: evidence for new players. AAPS J 8: E298-E306.
    • (2006) AAPS J , vol.8
    • Mackie, K.1    Stella, N.2
  • 75
    • 34250208223 scopus 로고    scopus 로고
    • Penguin: Melbourne
    • Marai S (2001). Embers. Penguin: Melbourne.
    • (2001) Embers
    • Marai, S.1
  • 76
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI (1990). Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346: 561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 77
    • 0014061503 scopus 로고
    • The absolute configuration of delta-1-tetrahydrocannabinol, the major active constituent of hashish
    • Mechoulam R, Gaoni Y (1967). The absolute configuration of delta-1-tetrahydrocannabinol, the major active constituent of hashish. Tetrahedron Lett 12: 1109-1111.
    • (1967) Tetrahedron Lett , vol.12 , pp. 1109-1111
    • Mechoulam, R.1    Gaoni, Y.2
  • 78
    • 0035929138 scopus 로고    scopus 로고
    • Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed
    • Mendizábal VE, Orliac ML, Adler-Graschinsky E (2001). Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed. Eur J Pharmacol 427: 251-262.
    • (2001) Eur J Pharmacol , vol.427 , pp. 251-262
    • Mendizábal, V.E.1    Orliac, M.L.2    Adler-Graschinsky, E.3
  • 79
    • 0036080330 scopus 로고    scopus 로고
    • Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent
    • Mukhopadhyay S, Chapnick BM, Howlett AC (2002). Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent. Am J Physiol Heart Circ Physiol 282: H2046-H2054.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Mukhopadhyay, S.1    Chapnick, B.M.2    Howlett, A.C.3
  • 80
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S, Thomas KL, Abu-Shaar M (1993). Molecular characterization of a peripheral receptor for cannabinoids. Nature 365: 61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 81
    • 0032929957 scopus 로고    scopus 로고
    • Effect of the cannabinoid receptor agonist WIN55212-2 on sympathetic cardiovascular regulation
    • Niederhoffer N, Szabo B (1999). Effect of the cannabinoid receptor agonist WIN55212-2 on sympathetic cardiovascular regulation. Br J Pharmacol 126: 457-466.
    • (1999) Br J Pharmacol , vol.126 , pp. 457-466
    • Niederhoffer, N.1    Szabo, B.2
  • 82
    • 0033928782 scopus 로고    scopus 로고
    • Cannabinoids cause central sympathoexcitation and bradycardia in rabbits
    • Niederhoffer N, Szabo B (2000). Cannabinoids cause central sympathoexcitation and bradycardia in rabbits. J Pharmacol Exp Ther 294: 707-713.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 707-713
    • Niederhoffer, N.1    Szabo, B.2
  • 84
    • 0242584643 scopus 로고    scopus 로고
    • Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor
    • Offertáler L, Mo FM, Batkai S, Liu J, Begg M, Razdan RK et al. (2003). Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor. Mol Pharmacol 63: 699-705.
    • (2003) Mol Pharmacol , vol.63 , pp. 699-705
    • Offertáler, L.1    Mo, F.M.2    Batkai, S.3    Liu, J.4    Begg, M.5    Razdan, R.K.6
  • 85
    • 0037215647 scopus 로고    scopus 로고
    • Potentiation of anandamide effects in mesenteric beds isolated from endotoxemic rats
    • Orliac ML, Peroni R, Celuch SM, Adler-Graschinsky E (2003). Potentiation of anandamide effects in mesenteric beds isolated from endotoxemic rats. J Pharmacol Exp Ther 304: 179-184.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 179-184
    • Orliac, M.L.1    Peroni, R.2    Celuch, S.M.3    Adler-Graschinsky, E.4
  • 86
    • 20944436157 scopus 로고    scopus 로고
    • Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
    • Osei-Hyiaman D, DePetrillo M, Pacher P, Liu J, Radaeva S, Batkai S et al. (2005). Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest 115: 1298-1305.
    • (2005) J Clin Invest , vol.115 , pp. 1298-1305
    • Osei-Hyiaman, D.1    DePetrillo, M.2    Pacher, P.3    Liu, J.4    Radaeva, S.5    Batkai, S.6
  • 88
    • 1842611872 scopus 로고    scopus 로고
    • Characterisation of the vasorelaxant properties of the novel endocannabinoid N-arachidonoyl- dopamine (NADA)
    • O'Sullivan SE, Kendall DA, Randall MD (2004). Characterisation of the vasorelaxant properties of the novel endocannabinoid N-arachidonoyl- dopamine (NADA). Br J Pharmacol 141: 803-812.
    • (2004) Br J Pharmacol , vol.141 , pp. 803-812
    • O'Sullivan, S.E.1    Kendall, D.A.2    Randall, M.D.3
  • 90
    • 19444369394 scopus 로고    scopus 로고
    • Blood pressure regulation by endocannabinoids and their receptors
    • Pacher P, Bátkai S, Kunos G (2005a). Blood pressure regulation by endocannabinoids and their receptors. Neuropharmacology 48: 1130-1138.
    • (2005) Neuropharmacology , vol.48 , pp. 1130-1138
    • Pacher, P.1    Bátkai, S.2    Kunos, G.3
  • 91
    • 33748703859 scopus 로고    scopus 로고
    • The endocannabinoid system as an emerging target of pharmacotherapy
    • Pacher P, Bátkai S, Kunos G (2006). The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 58: 389-462.
    • (2006) Pharmacol Rev , vol.58 , pp. 389-462
    • Pacher, P.1    Bátkai, S.2    Kunos, G.3
  • 92
  • 93
    • 0141923030 scopus 로고    scopus 로고
    • Cannabinoid receptor activation in the rostral ventrolateral medulla oblongata evokes cardiorespiratory effects in anaesthetised rats
    • Padley JR, Li Q, Pilowsky PM, Goodchild AK (2003). Cannabinoid receptor activation in the rostral ventrolateral medulla oblongata evokes cardiorespiratory effects in anaesthetised rats. Br J Pharmacol 140: 384-394.
    • (2003) Br J Pharmacol , vol.140 , pp. 384-394
    • Padley, J.R.1    Li, Q.2    Pilowsky, P.M.3    Goodchild, A.K.4
  • 94
    • 0027920980 scopus 로고
    • Pathogenetic mechanisms of septic shock
    • Parrillo JE (1993). Pathogenetic mechanisms of septic shock. N Engl J Med 328: 1471-1477.
    • (1993) N Engl J Med , vol.328 , pp. 1471-1477
    • Parrillo, J.E.1
  • 95
    • 33846374469 scopus 로고    scopus 로고
    • Participation of CGRP and prostanoids in the sex-linked differences of anandamide effects in mesenteric beds isolated from Sprague-Dawley rats
    • Peroni RN, Orliac ML, Abramoff T, Ribeiro ML, Franchi AM, Adler-Graschinsky E (2007). Participation of CGRP and prostanoids in the sex-linked differences of anandamide effects in mesenteric beds isolated from Sprague-Dawley rats. Eur J Pharmacol 557: 49-57.
    • (2007) Eur J Pharmacol , vol.557 , pp. 49-57
    • Peroni, R.N.1    Orliac, M.L.2    Abramoff, T.3    Ribeiro, M.L.4    Franchi, A.M.5    Adler-Graschinsky, E.6
  • 97
    • 15044357840 scopus 로고    scopus 로고
    • Search for an endogenous cannabinoid-mediated effect in the sympathetic nervous system
    • Pfitzer T, Niederhoffer N, Szabo B (2005). Search for an endogenous cannabinoid-mediated effect in the sympathetic nervous system. Naunyn-Schmiedeberg's Arch Pharmacol 371: 9-17.
    • (2005) Naunyn-Schmiedeberg's Arch Pharmacol , vol.371 , pp. 9-17
    • Pfitzer, T.1    Niederhoffer, N.2    Szabo, B.3
  • 98
    • 85136405858 scopus 로고    scopus 로고
    • Pi-Sunyer FX, Aronne LJ, Heshmati HM, Devin J, Rosenstock J, RIO-North America Study Group (2006). Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA 295: 761-775.
    • Pi-Sunyer FX, Aronne LJ, Heshmati HM, Devin J, Rosenstock J, RIO-North America Study Group (2006). Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA 295: 761-775.
  • 99
    • 0030812043 scopus 로고    scopus 로고
    • Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries
    • Plane F, Holland M, Waldron GL, Garland CJ, Boyle JP (1997). Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries. Br J Pharmacol 121: 1509-1512.
    • (1997) Br J Pharmacol , vol.121 , pp. 1509-1512
    • Plane, F.1    Holland, M.2    Waldron, G.L.3    Garland, C.J.4    Boyle, J.P.5
  • 101
    • 33750868226 scopus 로고    scopus 로고
    • N-arachidonylethanolamide relaxation of bovine coronary artery is not mediated by CB1 cannabinoid receptor
    • Pratt PF, Hillard CJ, Edgemond WS, Campbell WB (1998). N-arachidonylethanolamide relaxation of bovine coronary artery is not mediated by CB1 cannabinoid receptor. Am J Physiol 274: H375-H381.
    • (1998) Am J Physiol , vol.274
    • Pratt, P.F.1    Hillard, C.J.2    Edgemond, W.S.3    Campbell, W.B.4
  • 102
    • 0037204738 scopus 로고    scopus 로고
    • Cannabinoids inhibit pre- and postjunctionally sympathetic neurotransmission in rat mesenteric arteries
    • Ralevic V, Kendall DA (2002). Cannabinoids inhibit pre- and postjunctionally sympathetic neurotransmission in rat mesenteric arteries. Eur J Pharmacol 444: 171-181.
    • (2002) Eur J Pharmacol , vol.444 , pp. 171-181
    • Ralevic, V.1    Kendall, D.A.2
  • 105
    • 2542555018 scopus 로고    scopus 로고
    • The complexities of the cardiovascular actions of cannabinoids
    • Randall MD, Kendall DA, O'Sullivan S (2004). The complexities of the cardiovascular actions of cannabinoids. Br J Pharmacol 142: 20-26.
    • (2004) Br J Pharmacol , vol.142 , pp. 20-26
    • Randall, M.D.1    Kendall, D.A.2    O'Sullivan, S.3
  • 107
    • 0036142225 scopus 로고    scopus 로고
    • Endogenous cannabinoids: A new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat
    • Ros J, Claria J, To-Figueras J, Planaguma A, Cejudo-Martín P, Fernández-Varo G et al. (2002). Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat. Gastroenterology 122: 85-93.
    • (2002) Gastroenterology , vol.122 , pp. 85-93
    • Ros, J.1    Claria, J.2    To-Figueras, J.3    Planaguma, A.4    Cejudo-Martín, P.5    Fernández-Varo, G.6
  • 108
    • 0034604755 scopus 로고    scopus 로고
    • Inhibition of nitric oxide production in RAW264.7 macrophages by cannabinoids and palmitoylethanolamide
    • Ross RA, Brockie HC, Pertwee RG (2000). Inhibition of nitric oxide production in RAW264.7 macrophages by cannabinoids and palmitoylethanolamide. Eur J Pharmacol 401: 121-130.
    • (2000) Eur J Pharmacol , vol.401 , pp. 121-130
    • Ross, R.A.1    Brockie, H.C.2    Pertwee, R.G.3
  • 109
    • 0030791958 scopus 로고    scopus 로고
    • Anandamide and other N-acylethanolamines in mouse peritoneal macrophages
    • Schmid PC, Kuwae T, Krebsbach RJ, Schmid HH (1997). Anandamide and other N-acylethanolamines in mouse peritoneal macrophages. Chem Phys Lipids 87: 103-110.
    • (1997) Chem Phys Lipids , vol.87 , pp. 103-110
    • Schmid, P.C.1    Kuwae, T.2    Krebsbach, R.J.3    Schmid, H.H.4
  • 111
    • 0018566341 scopus 로고
    • The triple effect induced by delta 9-tetrahydrocannabinol on the rat blood pressure
    • Siqueira SW, Lapa AP, Ribeiro do Valle J (1979). The triple effect induced by delta 9-tetrahydrocannabinol on the rat blood pressure. Eur J Pharmacol 58: 351-357.
    • (1979) Eur J Pharmacol , vol.58 , pp. 351-357
    • Siqueira, S.W.1    Lapa, A.P.2    Ribeiro do Valle, J.3
  • 113
    • 33748581395 scopus 로고    scopus 로고
    • Cannabinoid receptors in atherosclerosis
    • Steffens S, Mach F (2006). Cannabinoid receptors in atherosclerosis. Curr Opin Lipidol 17: 519-526.
    • (2006) Curr Opin Lipidol , vol.17 , pp. 519-526
    • Steffens, S.1    Mach, F.2
  • 114
    • 17144400758 scopus 로고    scopus 로고
    • Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice
    • Steffens S, Veillard NR, Arnaud C, Pelli G, Burger F, Staub C et al. (2005). Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice. Nature 434: 782-786.
    • (2005) Nature , vol.434 , pp. 782-786
    • Steffens, S.1    Veillard, N.R.2    Arnaud, C.3    Pelli, G.4    Burger, F.5    Staub, C.6
  • 115
    • 84858998279 scopus 로고    scopus 로고
    • STRADIVARIUS Strategy to Reduce Atherosclerosis Development Involving Administration of Rimonabant, the Intravascular Ultrasound Study, Available at ,Accessed November 16 2006
    • STRADIVARIUS (Strategy to Reduce Atherosclerosis Development Involving Administration of Rimonabant - the Intravascular Ultrasound Study). Available at http://www.clinicaltrials.gov/ct/gui/show/NCT00124332?order=1,Accessed November 16 2006.
  • 116
    • 0033648166 scopus 로고    scopus 로고
    • From opiate pharmacology to opioid peptide physiology
    • Terenius L (2000). From opiate pharmacology to opioid peptide physiology. Ups J Med Sci 105: 1-15.
    • (2000) Ups J Med Sci , vol.105 , pp. 1-15
    • Terenius, L.1
  • 117
    • 33644928428 scopus 로고    scopus 로고
    • Rimonabant: A cannabinoid receptor blocker for the treatment of metabolic and cardiovascular risk factors
    • Tonstad S (2006). Rimonabant: a cannabinoid receptor blocker for the treatment of metabolic and cardiovascular risk factors. Nutr Metab Cardiovasc Dis 16: 156-162.
    • (2006) Nutr Metab Cardiovasc Dis , vol.16 , pp. 156-162
    • Tonstad, S.1
  • 118
    • 27744478054 scopus 로고    scopus 로고
    • Anandamide reduces infarct size in rat isolated hearts subjected to ischaemia-reperfusion by a novel cannabinoid mechanism
    • Underdown NJ, Hiley CR, Ford WR (2005). Anandamide reduces infarct size in rat isolated hearts subjected to ischaemia-reperfusion by a novel cannabinoid mechanism. Br J Pharmacol 146: 809-816.
    • (2005) Br J Pharmacol , vol.146 , pp. 809-816
    • Underdown, N.J.1    Hiley, C.R.2    Ford, W.R.3
  • 119
    • 17144382751 scopus 로고    scopus 로고
    • Van Gaal LF, Rissanen AM, Scheen AJ, Ziegler O, Rossner S, RIO-Europe Study Group (2005). Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 365: 1389-1397.
    • Van Gaal LF, Rissanen AM, Scheen AJ, Ziegler O, Rossner S, RIO-Europe Study Group (2005). Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 365: 1389-1397.
  • 121
    • 0031823187 scopus 로고    scopus 로고
    • Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension
    • Varga K, Wagner JA, Bridgen DT, Kunos G (1998). Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. FASEB J 12: 1035-1044.
    • (1998) FASEB J , vol.12 , pp. 1035-1044
    • Varga, K.1    Wagner, J.A.2    Bridgen, D.T.3    Kunos, G.4
  • 122
    • 0029743379 scopus 로고    scopus 로고
    • Cardiovascular effects of (-)-11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl in rats
    • Vidrio H, Sanchez-Salvatori MA, Medina M (1996). Cardiovascular effects of (-)-11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl in rats. J Cardiovasc Pharmacol 28: 332-336.
    • (1996) J Cardiovasc Pharmacol , vol.28 , pp. 332-336
    • Vidrio, H.1    Sanchez-Salvatori, M.A.2    Medina, M.3
  • 123
    • 0015967842 scopus 로고
    • Role of the central autonomic nervous system in the hypotension and bradycardia induced by (-)-delta 9-trans-tetrahydrocannabinol
    • Vollmer RR, Cavero I, Ertel RJ, Solomon TA, Buckley JP (1974). Role of the central autonomic nervous system in the hypotension and bradycardia induced by (-)-delta 9-trans-tetrahydrocannabinol. J Pharm Pharmacol 26: 186-192.
    • (1974) J Pharm Pharmacol , vol.26 , pp. 186-192
    • Vollmer, R.R.1    Cavero, I.2    Ertel, R.J.3    Solomon, T.A.4    Buckley, J.P.5
  • 124
    • 33748164344 scopus 로고    scopus 로고
    • 1 cannabinoid receptors mediates delayed cardioprotection induced by nitric oxide in rat isolated hearts
    • 1 cannabinoid receptors mediates delayed cardioprotection induced by nitric oxide in rat isolated hearts. J Cardiovasc Pharmacol 47: 650-655.
    • (2006) J Cardiovasc Pharmacol , vol.47 , pp. 650-655
    • Wagner, J.A.1    Abesser, M.2    Harvey-White, J.3    Ertl, G.4
  • 126
    • 0038753984 scopus 로고    scopus 로고
    • CB(1) cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction
    • Wagner JA, Hu K, Karcher J, Bauersachs J, Schafer A, Laser M et al. (2003). CB(1) cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction. Br J Pharmacol 138: 1251-1258.
    • (2003) Br J Pharmacol , vol.138 , pp. 1251-1258
    • Wagner, J.A.1    Hu, K.2    Karcher, J.3    Bauersachs, J.4    Schafer, A.5    Laser, M.6
  • 127
    • 0035816432 scopus 로고    scopus 로고
    • Hemodynamic effects of cannabinoids: Coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors
    • Wagner JA, Jarai Z, Batkai S, Kunos G (2001a). Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors. Eur J Pharmacol 423: 203-210.
    • (2001) Eur J Pharmacol , vol.423 , pp. 203-210
    • Wagner, J.A.1    Jarai, Z.2    Batkai, S.3    Kunos, G.4
  • 129
    • 0032924113 scopus 로고    scopus 로고
    • Mesenteric vasodilation mediated by endothelial anandamide receptors
    • Wagner JA, Varga K, Jarai Z, Kunos G (1999). Mesenteric vasodilation mediated by endothelial anandamide receptors. Hypertension 33: 429-434.
    • (1999) Hypertension , vol.33 , pp. 429-434
    • Wagner, J.A.1    Varga, K.2    Jarai, Z.3    Kunos, G.4
  • 130
    • 0031773354 scopus 로고    scopus 로고
    • Cardiovascular actions of cannabinoids and their generation during shock
    • Wagner JA, Varga K, Kunos G (1998). Cardiovascular actions of cannabinoids and their generation during shock. J Mol Med 76: 824-836.
    • (1998) J Mol Med , vol.76 , pp. 824-836
    • Wagner, J.A.1    Varga, K.2    Kunos, G.3
  • 131
    • 1842611884 scopus 로고    scopus 로고
    • Cannabinoids and neuroinflammation
    • Walter L, Stella N (2004). Cannabinoids and neuroinflammation. Br J Pharmacol 141: 775-785.
    • (2004) Br J Pharmacol , vol.141 , pp. 775-785
    • Walter, L.1    Stella, N.2
  • 132
    • 33644640980 scopus 로고    scopus 로고
    • 1-mediated depressor effects during high-salt intake: Role of anandamide
    • 1-mediated depressor effects during high-salt intake: role of anandamide. Hypertension 46: 986-991.
    • (2005) Hypertension , vol.46 , pp. 986-991
    • Wang, Y.1    Kaminski, N.E.2    Wang, D.H.3
  • 133
    • 0035399346 scopus 로고    scopus 로고
    • Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: Increase in endogenous cannabinoids in the sera of patients with endotoxic shock
    • Wang Y, Liu Y, Ito Y, Hashiguchi T, Kitajima I, Yamakuchi M et al. (2001). Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. Anal Biochem 294: 73-82.
    • (2001) Anal Biochem , vol.294 , pp. 73-82
    • Wang, Y.1    Liu, Y.2    Ito, Y.3    Hashiguchi, T.4    Kitajima, I.5    Yamakuchi, M.6
  • 134
    • 0031448804 scopus 로고    scopus 로고
    • A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery
    • White R, Hiley CR (1997). A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. Br J Pharmacol 122: 1573-1584.
    • (1997) Br J Pharmacol , vol.122 , pp. 1573-1584
    • White, R.1    Hiley, C.R.2
  • 135
    • 33846569044 scopus 로고    scopus 로고
    • Exercise reduces adipose tissue via cannabinoid receptor type 1 which is regulated by peroxisome proliferator-activated receptor-delta
    • Yan ZC, Liu DY, Zhang LL, Shen CY, Ma QL, Cao TB et al. (2007). Exercise reduces adipose tissue via cannabinoid receptor type 1 which is regulated by peroxisome proliferator-activated receptor-delta. Biochem Biophys Res Commun 354: 427-433.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 427-433
    • Yan, Z.C.1    Liu, D.Y.2    Zhang, L.L.3    Shen, C.Y.4    Ma, Q.L.5    Cao, T.B.6
  • 136
    • 0033614984 scopus 로고    scopus 로고
    • Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
    • Zygmunt PM, Petersson J, Andersson DA, Chuang H, Sorgard M, Di Marzo V et al. (1999). Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400: 452-457.
    • (1999) Nature , vol.400 , pp. 452-457
    • Zygmunt, P.M.1    Petersson, J.2    Andersson, D.A.3    Chuang, H.4    Sorgard, M.5    Di Marzo, V.6


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