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Volumn 126, Issue 2, 1999, Pages 457-466

Effect of the cannabinoid receptor agonist WIN55212-2 on sympathetic cardiovascular regulation

Author keywords

Baroreflex; Blood pressure; Cannabinoid receptor; Cardiovascular regulation; Conscious rabbit; Heart rate; Pithed rabbit; Plasma noradrenaline; Presynaptic receptor; Sympathetic nerve activity

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR AGONIST; NORADRENALIN; RIMONABANT;

EID: 0032929957     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702337     Document Type: Article
Times cited : (100)

References (46)
  • 2
    • 0016769009 scopus 로고
    • Cardiovascular effects of prolonged delta-9-tetrahydrocannabinol ingestion
    • Benowitz, N.L. & Jones, R.T. (1975). Cardiovascular effects of prolonged delta-9-tetrahydrocannabinol ingestion. Clin. Pharmacol. Ther., 18, 287-297.
    • (1975) Clin. Pharmacol. Ther. , vol.18 , pp. 287-297
    • Benowitz, N.L.1    Jones, R.T.2
  • 3
    • 0018384731 scopus 로고
    • Cardiovascular effects of intravenous delta-9-tetrahydrocannabinol: Autonomic nervous mechanisms
    • Benowitz, N.L , Rosenberg, J., Rogers, W., Bachman, J. & Jones, R.T. (1979). Cardiovascular effects of intravenous delta-9-tetrahydrocannabinol: Autonomic nervous mechanisms. Clin. Pharmacol. Ther., 25, 440-446.
    • (1979) Clin. Pharmacol. Ther. , vol.25 , pp. 440-446
    • Benowitz, N.L.1    Rosenberg, J.2    Rogers, W.3    Bachman, J.4    Jones, R.T.5
  • 4
    • 0015619724 scopus 로고
    • 9-tetrahydrocannabino\ in the blood pressure of hypertensive rats bearing regenerated adrenal glands
    • 9-tetrahydrocannabino\ in the blood pressure of hypertensive rats bearing regenerated adrenal glands. Br. J. Pharmacol., 48, 169-171.
    • (1973) Br. J. Pharmacol. , vol.48 , pp. 169-171
    • Birmingham, M.K.1
  • 9
    • 0022509199 scopus 로고
    • Cannabinoid pharmacology
    • Dewey, W.L. (1986). Cannabinoid pharmacology. Pharmacol. Rev., 38, 151-178.
    • (1986) Pharmacol. Rev. , vol.38 , pp. 151-178
    • Dewey, W.L.1
  • 10
    • 0025026511 scopus 로고
    • Overflow of catecholamine neurotransmitters to the circulation: Source, fate, and functions
    • Esler, M., Jennings, G., Lambert, G., Meredith, I., Horne, M. & Eisenhofer, G. (1990). Overflow of catecholamine neurotransmitters to the circulation: source, fate, and functions. Physiol. Rev., 70, 963-985.
    • (1990) Physiol. Rev. , vol.70 , pp. 963-985
    • Esler, M.1    Jennings, G.2    Lambert, G.3    Meredith, I.4    Horne, M.5    Eisenhofer, G.6
  • 13
    • 0019496897 scopus 로고
    • The cardiovascular and autonomic effects of repeated administration of Δ-9-tetrahydrocannabinol to rhesus monkeys
    • Fredericks, A.B., Benowitz, N.L. & Savanapridi, C.Y. (1981). The cardiovascular and autonomic effects of repeated administration of Δ-9-tetrahydrocannabinol to rhesus monkeys. J. Pharmacol. Exp. Ther., 216, 247-253.
    • (1981) J. Pharmacol. Exp. Ther. , vol.216 , pp. 247-253
    • Fredericks, A.B.1    Benowitz, N.L.2    Savanapridi, C.Y.3
  • 14
    • 0015696249 scopus 로고
    • Cardiovascular and respiratory effects of cannabis in cat and rat
    • Graham, J.D.P. & Li, D.M.F. (1973). Cardiovascular and respiratory effects of cannabis in cat and rat. Br. J. Pharmacol., 49, 1-10.
    • (1973) Br. J. Pharmacol. , vol.49 , pp. 1-10
    • Graham, J.D.P.1    Li, D.M.F.2
  • 16
    • 0028987880 scopus 로고
    • Pharmacology of cannabinoid receptors
    • Howlett, A.C. (1995). Pharmacology of cannabinoid receptors. Ann. Rev. Pharmacol. Toxicol., 35, 607-634.
    • (1995) Ann. Rev. Pharmacol. Toxicol. , vol.35 , pp. 607-634
    • Howlett, A.C.1
  • 19
    • 0018355807 scopus 로고
    • 9-tetrahydrocannabinol in conscious and morphine-chloralose-anesthetized dogs: Anesthetic influence on drug action
    • 9-tetrahydrocannabinol in conscious and morphine-chloralose-anesthetized dogs: anesthetic influence on drug action. Eur. J. Pharmacol., 53, 63-68.
    • (1978) Eur. J. Pharmacol. , vol.53 , pp. 63-68
    • Jandhyala, B.S.1    Hamed, A.T.2
  • 20
    • 0018974873 scopus 로고
    • 9-tetrahydrocannabinol on the cardiovascular system, and pressor and behavioral responses to brain stimulation in freely moving rats
    • 9-tetrahydrocannabinol on the cardiovascular system, and pressor and behavioral responses to brain stimulation in freely moving rats. Eur. J. Pharmacol., 65, 63-69.
    • (1980) Eur. J. Pharmacol. , vol.65 , pp. 63-69
    • Kawasaki, H.1    Watanabe, S.2    Ueki, S.3
  • 21
    • 0027379769 scopus 로고
    • Aminoalkylindole binding in rat cerebellum: Selective displacement by natural and synthetic cannabinoids
    • Kuster, J.E., Stevenson, J.I., Ward, S.J., D'Ambra, T.E. & Haycock, D.A. (1993). Aminoalkylindole binding in rat cerebellum: selective displacement by natural and synthetic cannabinoids. J. Pharmacol. Exp. Ther., 264, 1352-1363.
    • (1993) J. Pharmacol. Exp. Ther. , vol.264 , pp. 1352-1363
    • Kuster, J.E.1    Stevenson, J.I.2    Ward, S.J.3    D'Ambra, T.E.4    Haycock, D.A.5
  • 23
    • 0030991629 scopus 로고    scopus 로고
    • Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats
    • Lake, K.D., Martin, B.R., Kunos, G. & varga, K. (1997b). Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. Hypertension, 29, 1204-1210.
    • (1997) Hypertension , vol.29 , pp. 1204-1210
    • Lake, K.D.1    Martin, B.R.2    Kunos, G.3    Varga, K.4
  • 24
    • 0026560323 scopus 로고
    • Distribution of neuronal cannabinoid receptor in the adult rat brain: A comparative receptor binding radioautography and in situ hybridization histochemistry
    • Mailleux, P. & Vanderhaeghen, J.J. (1992). Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry. Neuroscience, 48, 655-668.
    • (1992) Neuroscience , vol.48 , pp. 655-668
    • Mailleux, P.1    Vanderhaeghen, J.J.2
  • 26
    • 0022448676 scopus 로고
    • Cellular effects of cannabinoids
    • Martin, B.R. (1986). Cellular effects of cannabinoids. Pharmacol. Rev., 38, 45-74.
    • (1986) Pharmacol. Rev. , vol.38 , pp. 45-74
    • Martin, B.R.1
  • 27
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda, L.A., Lolait, S.J., Brownstein, B.J., Young, A.C. & Bonner, T.I. (1990). Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature, 346, 561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, B.J.3    Young, A.C.4    Bonner, T.I.5
  • 28
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro, S., Thomas, K.L. & Abu-Shaar, M. (1993). Molecular characterization of a peripheral receptor for cannabinoids. Nature, 365, 61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 29
    • 0017620623 scopus 로고
    • 9-tetrahydrocannabinol and dimethyl-heptylpyran induced tachycardia in the conscious rat
    • 9-tetrahydrocannabinol and dimethyl-heptylpyran induced tachycardia in the conscious rat. Life Sci., 21, 1329-1336.
    • (1977) Life Sci. , vol.21 , pp. 1329-1336
    • Osgood, P.F.1    Howes, J.F.2
  • 31
    • 0026560734 scopus 로고
    • Inhibitory effects of certain enantiomeric cannabinoids in the mouse vas deferens and the myenteric plexus preparation of guinea-pig small intestine
    • Pertwee, R.G., Stevenson, L.A., Elrick, D.B., Mechoulam, R. & Corbett, A.D. (1992). Inhibitory effects of certain enantiomeric cannabinoids in the mouse vas deferens and the myenteric plexus preparation of guinea-pig small intestine. Br. J. Pharmacol., 105, 980-984.
    • (1992) Br. J. Pharmacol. , vol.105 , pp. 980-984
    • Pertwee, R.G.1    Stevenson, L.A.2    Elrick, D.B.3    Mechoulam, R.4    Corbett, A.D.5
  • 33
    • 0030868833 scopus 로고    scopus 로고
    • Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation
    • Randall, M.D. & Kendall, D. A. (1997). Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation. Eur. J. Pharmacol., 335, 205-209.
    • (1997) Eur. J. Pharmacol. , vol.335 , pp. 205-209
    • Randall, M.D.1    Kendall, D.A.2
  • 35
    • 0030425575 scopus 로고    scopus 로고
    • Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands
    • Showalter, V.M., Compton, D.R., Martin, B.R. & Abood, M.A. (1996). Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. J. Pharmacol. Exp. Ther., 278, 989-999.
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 989-999
    • Showalter, V.M.1    Compton, D.R.2    Martin, B.R.3    Abood, M.A.4
  • 36
    • 0018968572 scopus 로고
    • Cannabinoids. II. Cardiovascular effects
    • Stark, P. & Dews, P.B. (1980). Cannabinoids. II. Cardiovascular effects. J. Pharmacol. Exp. Ther., 214, 131-138.
    • (1980) J. Pharmacol. Exp. Ther. , vol.214 , pp. 131-138
    • Stark, P.1    Dews, P.B.2
  • 37
    • 0029812415 scopus 로고    scopus 로고
    • Physiological and behavioural effects of the endogenous cannabinoid, arachidonylethanolamide (anandamide), in the rat
    • Stein, E.A., Fuller, S.A., Edgemond, W.S. & Campbell, W.B. (1996). Physiological and behavioural effects of the endogenous cannabinoid, arachidonylethanolamide (anandamide), in the rat. Br. J. Pharmacol., 119, 107-114.
    • (1996) Br. J. Pharmacol. , vol.119 , pp. 107-114
    • Stein, E.A.1    Fuller, S.A.2    Edgemond, W.S.3    Campbell, W.B.4
  • 38
    • 0023275570 scopus 로고
    • ACTH increases noradrenaline release in pithed rabbits with electrically stimulated sympathetic outflow
    • Szabo, B., Hedler, L., Lichtwald, K. & Starke, K. (1987). ACTH increases noradrenaline release in pithed rabbits with electrically stimulated sympathetic outflow. Eur. J. Pharmacol., 136, 391-399.
    • (1987) Eur. J. Pharmacol. , vol.136 , pp. 391-399
    • Szabo, B.1    Hedler, L.2    Lichtwald, K.3    Starke, K.4
  • 39
    • 0025115535 scopus 로고
    • Desipramine inhibits sympathetic nerve activity in the rabbit
    • Szabo, B. & Schultheiss, A. (1990). Desipramine inhibits sympathetic nerve activity in the rabbit. Naunyn-Schmiedeberg's Arch. Pharmacol., 342, 469-476.
    • (1990) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.342 , pp. 469-476
    • Szabo, B.1    Schultheiss, A.2
  • 40
    • 0028917516 scopus 로고
    • Cardiovascular effects of agmatine, a 'clonidine-displacing substance', in conscious rabbits
    • Szabo, B., Urban, R., Limberger, N. & Starke, K. (1995). Cardiovascular effects of agmatine, a 'clonidine-displacing substance', in conscious rabbits. Naunyn-Schmiedeberg's Arch. Pharmacol., 351, 268-273.
    • (1995) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.351 , pp. 268-273
    • Szabo, B.1    Urban, R.2    Limberger, N.3    Starke, K.4
  • 42
    • 0029076015 scopus 로고
    • Involvement of peripheral presynaptic inhibition in the reduction of sympathetic tone by moxonidine, rilmenidine and UK 14304
    • Urban, R. Szabo, B. & Starke, K. (1995). Involvement of peripheral presynaptic inhibition in the reduction of sympathetic tone by moxonidine, rilmenidine and UK 14304. Eur. J. Pharmacol., 282, 29-37.
    • (1995) Eur. J. Pharmacol. , vol.282 , pp. 29-37
    • Urban, R.S.B.1    Starke, K.2
  • 43
    • 0029847296 scopus 로고    scopus 로고
    • Mechanism of the hypotensive action of anandamide in anesthetized rats
    • Varga, K., Lake, K.D., Huangfu, D., Guyenet, P.G. & Kunos, G. (1996). Mechanism of the hypotensive action of anandamide in anesthetized rats. Hypertension, 28, 682-686.
    • (1996) Hypertension , vol.28 , pp. 682-686
    • Varga, K.1    Lake, K.D.2    Huangfu, D.3    Guyenet, P.G.4    Kunos, G.5


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