-
1
-
-
0034928628
-
Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis
-
Bátkai S, Járai Z, Wagner JA, Goparaju SK, Varga K, Liu J, Wang L, Mirshahi F, Khanolkar AD, Makriyannis A, Urbascheck R, Garcia N Jr, Sanyal AJ & Kunos G (2001). Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. Nat Med 7, 827-832.
-
(2001)
Nat. Med.
, vol.7
, pp. 827-832
-
-
Bátkai, S.1
Járai, Z.2
Wagner, J.A.3
Goparaju, S.K.4
Varga, K.5
Liu, J.6
Wang, L.7
Mirshahi, F.8
Khanolkar, A.D.9
Makriyannis, A.10
Urbascheck, R.11
Garcia Jr., N.12
Sanyal, A.J.13
Kunos, G.14
-
2
-
-
0037379903
-
Cannabinoids acting on CB1 receptors decrease contractile performance in human atrial muscle
-
Bonz A, Laser M, Kullmer S, Kniesch S, Babin-Ebell J, Popp V, Ertl G & Wagner JA (2003). Cannabinoids acting on CB1 receptors decrease contractile performance in human atrial muscle. J Cardiovasc Pharmacol 41, 657-664.
-
(2003)
J. Cardiovasc. Pharmacol.
, vol.41
, pp. 657-664
-
-
Bonz, A.1
Laser, M.2
Kullmer, S.3
Kniesch, S.4
Babin-Ebell, J.5
Popp, V.6
Ertl, G.7
Wagner, J.A.8
-
3
-
-
0031758641
-
Interactions between synthetic vanilloids and the endogenous cannabinoids system
-
Di Marzo V, Bisogno T, Melck D, Ross R, Brockie H, Stevenson L, Pertwee R & De Petrocellis L (1998). Interactions between synthetic vanilloids and the endogenous cannabinoids system. FEBS Lett 436, 449-454.
-
(1998)
FEBS Lett.
, vol.436
, pp. 449-454
-
-
Di Marzo, V.1
Bisogno, T.2
Melck, D.3
Ross, R.4
Brockie, H.5
Stevenson, L.6
Pertwee, R.7
De Petrocellis, L.8
-
5
-
-
0035169841
-
Anandamide-induced relaxation of sheep coronary arteries: The role of the vascular endothelium, arachidonic acid metabolites and potassium channels
-
Grainger J & Boachie-Ansah G (2001). Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. Br J Pharmacol 134, 1003-1012.
-
(2001)
Br. J. Pharmacol.
, vol.134
, pp. 1003-1012
-
-
Grainger, J.1
Boachie-Ansah, G.2
-
6
-
-
0037088843
-
Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed
-
Harris D, McCulloch AI, Kendall DA & Randall MD (2002). Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed. J Physiol 539, 893-902.
-
(2002)
J. Physiol.
, vol.539
, pp. 893-902
-
-
Harris, D.1
McCulloch, A.I.2
Kendall, D.A.3
Randall, M.D.4
-
7
-
-
0033917648
-
Endocannabinoids and vascular function
-
Hillard CJ (2000). Endocannabinoids and vascular function. J Pharmacol Exp Ther 294, 27-32.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.294
, pp. 27-32
-
-
Hillard, C.J.1
-
8
-
-
0029786614
-
Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves
-
Ishac EJ, Jiang L, Lake KD, Varga K, Abood ME & Kunos G (1996). Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. Br J Pharmacol 118, 2023-2028.
-
(1996)
Br. J. Pharmacol.
, vol.118
, pp. 2023-2028
-
-
Ishac, E.J.1
Jiang, L.2
Lake, K.D.3
Varga, K.4
Abood, M.E.5
Kunos, G.6
-
9
-
-
0038845604
-
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors
-
Járai Z, Wagner JA, Varga K, Lake KD, Compton DR, Martin BR, Zimmer AM, Bonner TI, Buckley NE, Mezey E, Razdan RK, Zimmer A & Kunos G (1999). Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc Natl Acad Sci U S A 96, 14136-14141.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 14136-14141
-
-
Járai, Z.1
Wagner, J.A.2
Varga, K.3
Lake, K.D.4
Compton, D.R.5
Martin, B.R.6
Zimmer, A.M.7
Bonner, T.I.8
Buckley, N.E.9
Mezey, E.10
Razdan, R.K.11
Zimmer, A.12
Kunos, G.13
-
10
-
-
0042634735
-
Effects of the CGRP receptor antagonist BIBN4096BS on capsaicin-induced carotid haemodynamic changes in anaesthetised pigs
-
Kapoor K, Arulmani U, Heiligers JP, Garrelds IM, Willems EW, Doods H, Villalon CM & Saxena PR (2003). Effects of the CGRP receptor antagonist BIBN4096BS on capsaicin-induced carotid haemodynamic changes in anaesthetised pigs. Br J Pharmacol 140, 329-338.
-
(2003)
Br. J. Pharmacol.
, vol.140
, pp. 329-338
-
-
Kapoor, K.1
Arulmani, U.2
Heiligers, J.P.3
Garrelds, I.M.4
Willems, E.W.5
Doods, H.6
Villalon, C.M.7
Saxena, P.R.8
-
11
-
-
0023481279
-
Comparative influence of load versus inotropic states on indexes of ventricular contractility: Experimental and theoretical analysis based on pressure-volume relationships
-
Kass DA, Maughan WL, Guo ZM, Kono A, Sunagawa K & Sagawa K (1987). Comparative influence of load versus inotropic states on indexes of ventricular contractility: experimental and theoretical analysis based on pressure-volume relationships. Circulation 76, 1422-1436.
-
(1987)
Circulation
, vol.76
, pp. 1422-1436
-
-
Kass, D.A.1
Maughan, W.L.2
Guo, Z.M.3
Kono, A.4
Sunagawa, K.5
Sagawa, K.6
-
12
-
-
0037207080
-
The quest for a vascular endothelial cannabinoids receptor
-
Kunos G, Batkai S, Offertaler L, Mo F, Liu J, Karcher J & Harvey-White J (2002). The quest for a vascular endothelial cannabinoids receptor. Chem Physics Lipids 121, 45-56.
-
(2002)
Chem. Physics Lipids
, vol.121
, pp. 45-56
-
-
Kunos, G.1
Batkai, S.2
Offertaler, L.3
Mo, F.4
Liu, J.5
Karcher, J.6
Harvey-White, J.7
-
13
-
-
0030925426
-
Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors
-
Lake KD, Compton DR, Varga K, Martin BR & Kunos G (1997a). Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. J Pharmacol Exp Ther 281, 1030-1037.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.281
, pp. 1030-1037
-
-
Lake, K.D.1
Compton, D.R.2
Varga, K.3
Martin, B.R.4
Kunos, G.5
-
14
-
-
0030991629
-
Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats
-
Lake KD, Martin BR, Kunos G & Varga K (1997b). Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. Hypertension 29, 1204-1210.
-
(1997)
Hypertension
, vol.29
, pp. 1204-1210
-
-
Lake, K.D.1
Martin, B.R.2
Kunos, G.3
Varga, K.4
-
15
-
-
0033555839
-
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
-
Ledent C, Valverde O, Cossu G, Petitet F, Aubert JF, Beslot F, Bohme GA, Imperato A, Pedrazzini T, Roques BP, Vassart G, Fratta W & Parmentier M (1999). Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 283, 401-404.
-
(1999)
Science
, vol.283
, pp. 401-404
-
-
Ledent, C.1
Valverde, O.2
Cossu, G.3
Petitet, F.4
Aubert, J.F.5
Beslot, F.6
Bohme, G.A.7
Imperato, A.8
Pedrazzini, T.9
Roques, B.P.10
Vassart, G.11
Fratta, W.12
Parmentier, M.13
-
16
-
-
0037338753
-
Anandamide-induced depressor effect in spontaneously hypertensive rats: Role of the vanilloid receptor
-
Li J, Kaminski NE & Wang DH (2003). Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor. Hypertension 41, 757-762.
-
(2003)
Hypertension
, vol.41
, pp. 757-762
-
-
Li, J.1
Kaminski, N.E.2
Wang, D.H.3
-
17
-
-
0034653517
-
Functional CB1 cannabinoid receptors in human vascular endothelial cells
-
Liu J, Gao B, Mirshahi F, Sanyal AJ, Khanolkar AD, Makriyannis A & Kunos G (2000). Functional CB1 cannabinoid receptors in human vascular endothelial cells. Biochem J 346, 835-840.
-
(2000)
Biochem. J.
, vol.346
, pp. 835-840
-
-
Liu, J.1
Gao, B.2
Mirshahi, F.3
Sanyal, A.J.4
Khanolkar, A.D.5
Makriyannis, A.6
Kunos, G.7
-
18
-
-
0035210486
-
Anandamide and methanandamide induce both vanilloid VR1- And cannabinoids CB1 receptor-mediated changes in heart rate and blood pressure in anaesthetized rats
-
Malinowska B, Kwolek G & Gothert M (2001). Anandamide and methanandamide induce both vanilloid VR1- and cannabinoids CB1 receptor-mediated changes in heart rate and blood pressure in anaesthetized rats. Naunyn Schmiedebergs Arch Pharmacol 364, 562-569.
-
(2001)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.364
, pp. 562-569
-
-
Malinowska, B.1
Kwolek, G.2
Gothert, M.3
-
19
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda LA, Lolait SJ, Brownstein MJ, Young CA & Bonner TI (1990). Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346, 561-564.
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, C.A.4
Bonner, T.I.5
-
21
-
-
0036080330
-
Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent
-
Mukhopadhyay S, Chapnick BM & Howlett AC (2002). Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent. Am J Physiol 282, H2046-H2054.
-
(2002)
Am. J. Physiol.
, vol.282
-
-
Mukhopadhyay, S.1
Chapnick, B.M.2
Howlett, A.C.3
-
22
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro S, Thomas KL & Abu-Shaar M (1993). Molecular characterization of a peripheral receptor for cannabinoids. Nature 365, 61-65.
-
(1993)
Nature
, vol.365
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
23
-
-
0025552862
-
Myocardial stiffness derived from end-systolic wall stress and logarithm of reciprocal of wall thickness. Contractility index independent of ventricular size
-
Nakano K, Sugawara M, Ishihara K, Kanazawa S, Corin WJ, Denslow S, Biederman RW & Carabello BA (1990). Myocardial stiffness derived from end-systolic wall stress and logarithm of reciprocal of wall thickness. Contractility index independent of ventricular size. Circulation 82, 1352-1361.
-
(1990)
Circulation
, vol.82
, pp. 1352-1361
-
-
Nakano, K.1
Sugawara, M.2
Ishihara, K.3
Kanazawa, S.4
Corin, W.J.5
Denslow, S.6
Biederman, R.W.7
Carabello, B.A.8
-
24
-
-
0033928782
-
Cannabinoids cause central sympathoexcitation and bradycardia in rabbits
-
Niederhoffer N & Szabo B (2000). Cannabinoids cause central sympathoexcitation and bradycardia in rabbits. J Pharmacol Exp Ther 294, 707-713.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.294
, pp. 707-713
-
-
Niederhoffer, N.1
Szabo, B.2
-
25
-
-
0037448784
-
Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction
-
Pacher P, Liaudet L, Bai P, Mabley JG, Kaminski PM, Virag L, Deb A, Szabo E, Ungvari Z, Wolin MS, Groves JT & Szabo C (2003). Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction. Circulation 107, 896-904.
-
(2003)
Circulation
, vol.107
, pp. 896-904
-
-
Pacher, P.1
Liaudet, L.2
Bai, P.3
Mabley, J.G.4
Kaminski, P.M.5
Virag, L.6
Deb, A.7
Szabo, E.8
Ungvari, Z.9
Wolin, M.S.10
Groves, J.T.11
Szabo, C.12
-
26
-
-
0036175161
-
Activation of poly (ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure
-
Pacher P, Liaudet L, Bai P, Virag L, Mabley JG, Hasko G & Szabo C (2002a). Activation of poly (ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure. J Pharmacol Exp Ther 300, 862-867.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 862-867
-
-
Pacher, P.1
Liaudet, L.2
Bai, P.3
Virag, L.4
Mabley, J.G.5
Hasko, G.6
Szabo, C.7
-
27
-
-
0037019589
-
Pharmacologic inhibition of poly (adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure
-
Pacher P, Liaudet L, Mabley J, Komjati K & Szabo C (2002b). Pharmacologic inhibition of poly (adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure. J Am Coll Cardiol 40, 1006-1016.
-
(2002)
J. Am. Coll. Cardiol.
, vol.40
, pp. 1006-1016
-
-
Pacher, P.1
Liaudet, L.2
Mabley, J.3
Komjati, K.4
Szabo, C.5
-
28
-
-
0036064154
-
The role of poly (ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes
-
Pacher P, Liaudet L, Soriano FG, Mabley JG, Szabo E & Szabo C (2002c). The role of poly (ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes. Diabetes 51, 514-521.
-
(2002)
Diabetes
, vol.51
, pp. 514-521
-
-
Pacher, P.1
Liaudet, L.2
Soriano, F.G.3
Mabley, J.G.4
Szabo, E.5
Szabo, C.6
-
29
-
-
0037131531
-
Cannabinoid modulation of sensory neurotransmission via cannabinoid and vanilloid receptors: Roles in regulation of cardiovascular function
-
Ralevic V, Kendall DA, Randall MD & Smart D (2002). Cannabinoid modulation of sensory neurotransmission via cannabinoid and vanilloid receptors: Roles in regulation of cardiovascular function. Life Sci 71, 2577-2594.
-
(2002)
Life Sci.
, vol.71
, pp. 2577-2594
-
-
Ralevic, V.1
Kendall, D.A.2
Randall, M.D.3
Smart, D.4
-
30
-
-
0033853422
-
Vanilloid receptors on capsaicin-sensitive sensory nerves mediate relaxation to methanandamide in the rat isolated mesenteric arterial bed and small mesenteric arteries
-
Ralevic V, Kendall DA, Randall MD, Zygmunt PM, Movahed P & Hogestatt ED (2000). Vanilloid receptors on capsaicin-sensitive sensory nerves mediate relaxation to methanandamide in the rat isolated mesenteric arterial bed and small mesenteric arteries. Br J Pharmacol 130, 1483-1488.
-
(2000)
Br. J. Pharmacol.
, vol.130
, pp. 1483-1488
-
-
Ralevic, V.1
Kendall, D.A.2
Randall, M.D.3
Zygmunt, P.M.4
Movahed, P.5
Hogestatt, E.D.6
-
32
-
-
0242610876
-
Capsazepine protects against neuronal injury caused by oxygen glucosae deprivation by inhibiting I(h)
-
Ray AM, Benham CD, Roberts JC, Gill CH, Lanneau C, Gitterman DP, Harries M, Davis JB & Davies CH (2003). Capsazepine protects against neuronal injury caused by oxygen glucosae deprivation by inhibiting I(h). J Neurosci 23, 10146-10153.
-
(2003)
J. Neurosci.
, vol.23
, pp. 10146-10153
-
-
Ray, A.M.1
Benham, C.D.2
Roberts, J.C.3
Gill, C.H.4
Lanneau, C.5
Gitterman, D.P.6
Harries, M.7
Davis, J.B.8
Davies, C.H.9
-
33
-
-
0033976691
-
Are cannabinoids endogenous ligands for the VR1 capsaicin receptor?
-
Szolcsányi J (2000). Are cannabinoids endogenous ligands for the VR1 capsaicin receptor? Trends Pharmacol Sci 21, 41-42.
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, pp. 41-42
-
-
Szolcsányi, J.1
-
34
-
-
0029847296
-
Mechanism of the hypotensive action of anandamide in anesthetized rats
-
Varga K, Lake KD, Huangfu D, Guyenet PG & Kunos G (1996). Mechanism of the hypotensive action of anandamide in anesthetized rats. Hypertension 28, 682-686.
-
(1996)
Hypertension
, vol.28
, pp. 682-686
-
-
Varga, K.1
Lake, K.D.2
Huangfu, D.3
Guyenet, P.G.4
Kunos, G.5
-
35
-
-
0029055851
-
Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide
-
Varga K, Lake K, Martin BR & Kunos G (1995). Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide. Eur J Pharmacol 278, 279-283.
-
(1995)
Eur. J. Pharmacol.
, vol.278
, pp. 279-283
-
-
Varga, K.1
Lake, K.2
Martin, B.R.3
Kunos, G.4
-
36
-
-
0031823187
-
Platelet-and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension
-
Varga K, Wagner JA, Bridgen DT & Kunos G (1998). Platelet-and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. FASEB J 12, 1035-1044.
-
(1998)
FASEB J.
, vol.12
, pp. 1035-1044
-
-
Varga, K.1
Wagner, J.A.2
Bridgen, D.T.3
Kunos, G.4
-
37
-
-
0035203968
-
Endogenous cannabinoids mediate hypotension after experimental myocardial infarction
-
Wagner JA, Hu K, Bauersachs J, Karcher J, Wiesler M, Goparaju SK, Kunos G & Ertl G (2001a). Endogenous cannabinoids mediate hypotension after experimental myocardial infarction. J Am Coll Cardiol 38, 2048- 2054.
-
(2001)
J. Am. Coll. Cardiol.
, vol.38
, pp. 2048-2054
-
-
Wagner, J.A.1
Hu, K.2
Bauersachs, J.3
Karcher, J.4
Wiesler, M.5
Goparaju, S.K.6
Kunos, G.7
Ertl, G.8
-
38
-
-
0035816432
-
Haemodynamic effects of cannabinoids: Coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors
-
Wagner JA, Járai Z, Bátkai S & Kunos G (2001b). Haemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors. Eur J Pharmacol 423, 203-210.
-
(2001)
Eur. J. Pharmacol.
, vol.423
, pp. 203-210
-
-
Wagner, J.A.1
Járai, Z.2
Bátkai, S.3
Kunos, G.4
-
39
-
-
0031284976
-
Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock
-
Wagner JA, Varga K, Ellis EF, Rzigalinski BA, Martin BR & Kunos G (1997). Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. Nature 390, 518-521.
-
(1997)
Nature
, vol.390
, pp. 518-521
-
-
Wagner, J.A.1
Varga, K.2
Ellis, E.F.3
Rzigalinski, B.A.4
Martin, B.R.5
Kunos, G.6
-
40
-
-
0034749825
-
Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries
-
White R, Ho WS, Bottrill FE, Ford WR & Hiley CR (2001). Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. Br J Pharmacol 134, 921-929.
-
(2001)
Br. J. Pharmacol.
, vol.134
, pp. 921-929
-
-
White, R.1
Ho, W.S.2
Bottrill, F.E.3
Ford, W.R.4
Hiley, C.R.5
-
41
-
-
0141476269
-
Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats
-
Zahner MR, Li DP, Chen SR & Pan HL (2003). Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats. J Physiol 551, 515-523.
-
(2003)
J. Physiol.
, vol.551
, pp. 515-523
-
-
Zahner, M.R.1
Li, D.P.2
Chen, S.R.3
Pan, H.L.4
-
42
-
-
0036617759
-
Delta 9-tetrahydrocannabinol and cannabinol activate capsaicin-sensitive sensory nerves via a CB1 and CB2 cannabinoid receptor-independent mechanism
-
Zygmunt PM, Andersson DA & Högestätt ED (2002). Delta 9-tetrahydrocannabinol and cannabinol activate capsaicin-sensitive sensory nerves via a CB1 and CB2 cannabinoid receptor-independent mechanism. J Neurosci 22, 4720-4727.
-
(2002)
J. Neurosci.
, vol.22
, pp. 4720-4727
-
-
Zygmunt, P.M.1
Andersson, D.A.2
Högestätt, E.D.3
-
43
-
-
0033614984
-
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
-
Zygmunt PM, Petersson J, Andersson DA, Chuang H-H, Sorgard M, Di Marzo V, Julius D & Högestätt ED (1999). Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400, 452-457.
-
(1999)
Nature
, vol.400
, pp. 452-457
-
-
Zygmunt, P.M.1
Petersson, J.2
Andersson, D.A.3
Chuang, H.-H.4
Sorgard, M.5
Di Marzo, V.6
Julius, D.7
Högestätt, E.D.8
|