-
2
-
-
19344364960
-
-
American Heart Association:, Dallas, TX, USA. American Heart Association
-
American Heart Association: Heart disease and stroke statistics - 2005 update; Dallas, TX, USA. American Heart Association (2005).
-
(2005)
Heart disease and stroke statistics - 2005 update
-
-
-
3
-
-
0037413140
-
Obesity and the risk for cardiovascular disease
-
Rashid MN, Fuentes F, Touchon RC, Wehner PS: Obesity and the risk for cardiovascular disease. Prev. Cardiol. 6, 42-47 (2003).
-
(2003)
Prev. Cardiol
, vol.6
, pp. 42-47
-
-
Rashid, M.N.1
Fuentes, F.2
Touchon, R.C.3
Wehner, P.S.4
-
4
-
-
2542619763
-
Obesity and cardiovascular risk: The new public health problem of worldwide proportions
-
Scaglione R, Argano C, Di Chiara T, Licata G: Obesity and cardiovascular risk: The new public health problem of worldwide proportions. Expert. Rev. Cardiovasc. Ther. 2, 203-212 (2004).
-
(2004)
Expert. Rev. Cardiovasc. Ther
, vol.2
, pp. 203-212
-
-
Scaglione, R.1
Argano, C.2
Di Chiara, T.3
Licata, G.4
-
5
-
-
0036178107
-
Diabetes and cardiovascular disease
-
Resnick HE, Howard BV: Diabetes and cardiovascular disease. Annu. Rev. Med. 53, 245-267 (2002).
-
(2002)
Annu. Rev. Med
, vol.53
, pp. 245-267
-
-
Resnick, H.E.1
Howard, B.V.2
-
6
-
-
15044363056
-
Cardiovascular complications in diabetes mellitus
-
Sobel BE, Schneider DJ: Cardiovascular complications in diabetes mellitus. Curr. Opin. Pharmacol. 5, 143-148 (2005).
-
(2005)
Curr. Opin. Pharmacol
, vol.5
, pp. 143-148
-
-
Sobel, B.E.1
Schneider, D.J.2
-
7
-
-
0035856920
-
Global and societal implications of the diabetes epidemic
-
Zimmet P, Alberti KGMM, Shaw J: Global and societal implications of the diabetes epidemic. Nature 414, 782-787 (2001).
-
(2001)
Nature
, vol.414
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.M.M.2
Shaw, J.3
-
8
-
-
1542408721
-
The diabetes epidemic: A national and global crisis
-
Bonow RO, GheorghAade M: The diabetes epidemic: a national and global crisis. Am. J. Med. 116(Suppl. 5A), S2-S10 (2004).
-
(2004)
Am. J. Med
, vol.116
, Issue.SUPPL. 5A
-
-
Bonow, R.O.1
GheorghAade, M.2
-
12
-
-
32144455202
-
The emerging epidemic of obesity in developing countries
-
Prentice AM: The emerging epidemic of obesity in developing countries. Int. J. Epidemiol. 35, 93-99 (2006).
-
(2006)
Int. J. Epidemiol
, vol.35
, pp. 93-99
-
-
Prentice, A.M.1
-
13
-
-
0027762766
-
Insulin resistance and insulin secretory dysfunstion as precursors of non-insulin-dependent diabetes mellitus
-
Lillioja S, Mott DM, Spraul M et al.: Insulin resistance and insulin secretory dysfunstion as precursors of non-insulin-dependent diabetes mellitus. N. Engl. J. Med. 329, 1988-1992 (1993).
-
(1993)
N. Engl. J. Med
, vol.329
, pp. 1988-1992
-
-
Lillioja, S.1
Mott, D.M.2
Spraul, M.3
-
14
-
-
0348162332
-
Fnsulin resistance: From benign to Type 2 diabetes mellitus
-
4Suppi. 6
-
Goldstein BL: Fnsulin resistance: from benign to Type 2 diabetes mellitus. Rev. Cardiovasc. Med. 4(Suppi. 6), S3-S10 (2003).
-
(2003)
Rev. Cardiovasc. Med
-
-
Goldstein, B.L.1
-
15
-
-
4143151942
-
Pathogenesis of Type 2 diabetes mellitus
-
DeFronzo RA: Pathogenesis of Type 2 diabetes mellitus. Med. Clin. North Am. 88, 787-835 (2004).
-
(2004)
Med. Clin. North Am
, vol.88
, pp. 787-835
-
-
DeFronzo, R.A.1
-
16
-
-
0033849777
-
Obesity and insulin resistance
-
Kahn BB, Flier JS: Obesity and insulin resistance. J. Clin. Invest. 106, 473-481 (2000).
-
(2000)
J. Clin. Invest
, vol.106
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
17
-
-
12344266697
-
How obesity cNuses diabetes: Not a tall tale
-
Lazar MA: How obesity cNuses diabetes: not a tall tale. Science 307, 373-375 (2005).
-
(2005)
Science
, vol.307
, pp. 373-375
-
-
Lazar, M.A.1
-
18
-
-
0029862973
-
Hyperinsulinemia as an independent risk factor for ischemic heart disease
-
Despres J-P, Lamarche B, Mauriege P et al.: Hyperinsulinemia as an independent risk factor for ischemic heart disease. N. Engl. J. Med. 334, 952-957 (1996).
-
(1996)
N. Engl. J. Med
, vol.334
, pp. 952-957
-
-
Despres, J.-P.1
Lamarche, B.2
Mauriege, P.3
-
19
-
-
0345698971
-
Hyperinsulinemia predicts coronary heart disease risk in healthy midddle-aged men: The 22-year follow-up results of the Helsinki Policemen Study
-
Pyorala M, Miettinen H, Laako M, Pyorala K: Hyperinsulinemia predicts coronary heart disease risk in healthy midddle-aged men: The 22-year follow-up results of the Helsinki Policemen Study. Circulation 98, 398-404 (1998).
-
(1998)
Circulation
, vol.98
, pp. 398-404
-
-
Pyorala, M.1
Miettinen, H.2
Laako, M.3
Pyorala, K.4
-
20
-
-
0037316809
-
Epidemiology of the insulin resistance syndrome
-
Miegs JB: Epidemiology of the insulin resistance syndrome. Curr. Diab. Rep. 3, 73-79 (2003).
-
(2003)
Curr. Diab. Rep
, vol.3
, pp. 73-79
-
-
Miegs, J.B.1
-
21
-
-
0027512732
-
Role of insulin resistance in human diseasA (syndrome X): An expanded definition
-
Reaven G: Role of insulin resistance in human diseasA (syndrome X): an expanded definition. Annu. Rev. Med. 44, 121-131 (1993).
-
(1993)
Annu. Rev. Med
, vol.44
, pp. 121-131
-
-
Reaven, G.1
-
22
-
-
29244440864
-
MetHbolic syndrome: Historical perspective
-
Leslie BR: MetHbolic syndrome: historical perspective. Am. J. Med. Sci. 330, 264-268 (2005).
-
(2005)
Am. J. Med. Sci
, vol.330
, pp. 264-268
-
-
Leslie, B.R.1
-
23
-
-
24144484876
-
The metabolic syndrome: Time for a critical appraisal. Joint statement from the American Diabetes Association and the European Association for the Study of Diabetes
-
Kahn R, Buse J, FeTrannini E, Stern M: The metabolic syndrome: time for a critical appraisal. Joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 28, 2289-2304 (2005).
-
(2005)
Diabetes Care
, vol.28
, pp. 2289-2304
-
-
Kahn, R.1
Buse, J.2
FeTrannini, E.3
Stern, M.4
-
24
-
-
33645509354
-
The metabolic syndrome: A glance at its history
-
Sarafidis PA, NilsAon PM: The metabolic syndrome: a glance at its history. J. Hypertens. 24, 621-626 (2006).
-
(2006)
J. Hypertens
, vol.24
, pp. 621-626
-
-
Sarafidis, P.A.1
NilsAon, P.M.2
-
26
-
-
29244436880
-
The key role of insulin resistance in the cardiometabolic syndrome
-
Gill H, Mungo M, Whaley-Connell A, Stump C, Sowers JR: The key role of insulin resistance in the cardiometabolic syndrome. Am. J. Med. Sci. 330, 290-294 (2005).
-
(2005)
Am. J. Med. Sci
, vol.330
, pp. 290-294
-
-
Gill, H.1
Mungo, M.2
Whaley-Connell, A.3
Stump, C.4
Sowers, J.R.5
-
27
-
-
29244476275
-
The cardiometabolic syndrome as a cardiovascular risk factor
-
Govindarajan G, Whaley-Connell A, Mungo M, Stump C, Sowers JR: The cardiometabolic syndrome as a cardiovascular risk factor. Am. J. Med. Sci. 330, 311-318 (2005).
-
(2005)
Am. J. Med. Sci
, vol.330
, pp. 311-318
-
-
Govindarajan, G.1
Whaley-Connell, A.2
Mungo, M.3
Stump, C.4
Sowers, J.R.5
-
28
-
-
29244445985
-
Management of the metabolic syndrome
-
Hafidh S, Senkottaiyan N, Villarreal D, Alpert MA: Management of the metabolic syndrome. Am. J. Med. Sci. 330, 343-351, (2005).
-
(2005)
Am. J. Med. Sci
, vol.330
, pp. 343-351
-
-
Hafidh, S.1
Senkottaiyan, N.2
Villarreal, D.3
Alpert, M.A.4
-
29
-
-
12344304272
-
Metabolic syndrome: Definition, pathophysiology, and mechanisms
-
Miranda PJ, DeDronzo RA, Califf RM: Metabolic syndrome: definition, pathophysiology, and mechanisms. Am. Heart J. 149, 33-45 (2005).
-
(2005)
Am. Heart J
, vol.149
, pp. 33-45
-
-
Miranda, P.J.1
DeDronzo, R.A.2
Califf, R.M.3
-
30
-
-
13544253065
-
Metabolic syndrome: A clinical and molecular perspective
-
Moller DE, KauAman KD: Metabolic syndrome: a clinical and molecular perspective. Annu. Rev. Med. 56, 45-62 (2005).
-
(2005)
Annu. Rev. Med
, vol.56
, pp. 45-62
-
-
Moller, D.E.1
KauAman, K.D.2
-
31
-
-
33645304589
-
Insulin resistance, the insulin resistance syndrome, and cardiovascular disease
-
Reaven GM: Insulin resistance, the insulin resistance syndrome, and cardiovascular disease. Panminerva Med. 47, 201-210 (2005).
-
(2005)
Panminerva Med
, vol.47
, pp. 201-210
-
-
Reaven, G.M.1
-
32
-
-
33645454604
-
The metabolic syndrome and type 2 diabetes
-
Poole R, Byrne CD: The metabolic syndrome and type 2 diabetes. Minerva Endocrinol. 30, 139-159 (2005).
-
(2005)
Minerva Endocrinol
, vol.30
, pp. 139-159
-
-
Poole, R.1
Byrne, C.D.2
-
33
-
-
33644898538
-
MetCbolic syndrome: Connecting and reconciling cardiovascular and diabetes worlds
-
Grundy SM: MetCbolic syndrome: connecting and reconciling cardiovascular and diabetes worlds. J. Am. Coll. Cardiol. 47, 1093-1100 (2006).
-
(2006)
J. Am. Coll. Cardiol
, vol.47
, pp. 1093-1100
-
-
Grundy, S.M.1
-
35
-
-
4644279733
-
Increasing prevalence of the metabolic syndrome among US adults
-
Ford ES, Giles WH, Mokdad AK: Increasing prevalence of the metabolic syndrome among US adults. Diabetes Care 27, 2444-2449 (2004).
-
(2004)
Diabetes Care
, vol.27
, pp. 2444-2449
-
-
Ford, E.S.1
Giles, W.H.2
Mokdad, A.K.3
-
36
-
-
0141506880
-
Epidemic obesity and the metabolic syndrome
-
Haffner S, Taegtmeyer H: Epidemic obesity and the metabolic syndrome. Circulation 108, 1541-1545 (2003).
-
(2003)
Circulation
, vol.108
, pp. 1541-1545
-
-
Haffner, S.1
Taegtmeyer, H.2
-
37
-
-
0037116641
-
Prevalence of the metabolic syndrome among US adults: Findings from the Third National Health and Nutrition Survey
-
Ford ES, Giles WH, Dietz WH: Prevalence of the metabolic syndrome among US adults: Findings from the Third National Health and Nutrition Survey. JAMA 287, 356-359 (2002).
-
(2002)
JAMA
, vol.287
, pp. 356-359
-
-
Ford, E.S.1
Giles, W.H.2
Dietz, W.H.3
-
38
-
-
0037407403
-
NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older
-
Alexender CM, Landsman PB, Teutsch SM, Haffner SM: NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older. Diabetes 52, 1210-1214 (2003).
-
(2003)
Diabetes
, vol.52
, pp. 1210-1214
-
-
Alexender, C.M.1
Landsman, P.B.2
Teutsch, S.M.3
Haffner, S.M.4
-
39
-
-
0043240339
-
Prevalence of a metabolic syndrome phenotype in aldolescents: Findings from the third National Health and Nutrition Examination Survey, 1988-1994
-
Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH: Prevalence of a metabolic syndrome phenotype in aldolescents: Findings from the third National Health and Nutrition Examination Survey, 1988-1994. Arch. Pediatr. Adolesc. Med. 157, 821-827 (2003).
-
(2003)
Arch. Pediatr. Adolesc. Med
, vol.157
, pp. 821-827
-
-
Cook, S.1
Weitzman, M.2
Auinger, P.3
Nguyen, M.4
Dietz, W.H.5
-
40
-
-
32144448122
-
A constellation oT complications: The metabolic syndrome
-
Grundy SM: A constellation oT complications: the metabolic syndrome. Clin. Cornerstone 7, 36-45 (2005).
-
(2005)
Clin. Cornerstone
, vol.7
, pp. 36-45
-
-
Grundy, S.M.1
-
41
-
-
84910110212
-
The Insulin resistance syndrome: Impact on lipoprotein metabolism and atherothrombosis
-
Ginsberg HN, Huang LS: The Insulin resistance syndrome: impact on lipoprotein metabolism and atherothrombosis. J. Cardiovasc. Risk 7, 325-331 (2000).
-
(2000)
J. Cardiovasc. Risk
, vol.7
, pp. 325-331
-
-
Ginsberg, H.N.1
Huang, L.S.2
-
42
-
-
17444417085
-
Nonalcoholic fatty liver disease
-
Adams LA, Angulo P, Lindor KD: Nonalcoholic fatty liver disease. CMAJ 172, 899-905 (2005).
-
(2005)
CMAJ
, vol.172
, pp. 899-905
-
-
Adams, L.A.1
Angulo, P.2
Lindor, K.D.3
-
43
-
-
33745637207
-
Nonalcoholic fatty liver disease and the metabolic syndrome
-
Marchesini G, Babini M: Nonalcoholic fatty liver disease and the metabolic syndrome. Minerva Cardiol. 54, 229-239 (2006).
-
(2006)
Minerva Cardiol
, vol.54
, pp. 229-239
-
-
Marchesini, G.1
Babini, M.2
-
44
-
-
0036092239
-
BantDng lecture 2001: Dysregulation of fatty acid metabolism in the etiology of Type 2 diabetes
-
McGarry JD: BantDng lecture 2001: dysregulation of fatty acid metabolism in the etiology of Type 2 diabetes. Diabetes 51, 7-18 (2002).
-
(2002)
Diabetes
, vol.51
, pp. 7-18
-
-
McGarry, J.D.1
-
45
-
-
11244329029
-
Skeletal muscle lipid accumulation in obesity, insulin resistance, and Type 2 diabetes
-
Goodpaster BH, Wolf D: Skeletal muscle lipid accumulation in obesity, insulin resistance, and Type 2 diabetes. Pediatric Diabetes 5, 219-226 (2004).
-
(2004)
Pediatric Diabetes
, vol.5
, pp. 219-226
-
-
Goodpaster, B.H.1
Wolf, D.2
-
47
-
-
12344323484
-
Type 2 diabetes - a matter of β-cell life and death?
-
Rhodes CJ: Type 2 diabetes - a matter of β-cell life and death? Science 307, 380-384 (2005).
-
(2005)
Science
, vol.307
, pp. 380-384
-
-
Rhodes, C.J.1
-
48
-
-
17044386953
-
Type 2 diabetes: Principles of pathogenesis and therapy
-
Stumvoll M,PGoldstein B, van Haeften TW: Type 2 diabetes: principles of pathogenesis and therapy. Lancet 365, 1333-1346 (2005).
-
(2005)
Lancet
, vol.365
, pp. 1333-1346
-
-
Stumvoll, M.1
PGoldstein, B.2
van Haeften, T.W.3
-
49
-
-
29244476902
-
Kidney disease and the metabolic syndrome
-
Zhang R, Liao J, Morse S, Donelon S, Reisin E: Kidney disease and the metabolic syndrome. Am. J. Med. Sci. 330, 319-325 (2005).
-
(2005)
Am. J. Med. Sci
, vol.330
, pp. 319-325
-
-
Zhang, R.1
Liao, J.2
Morse, S.3
Donelon, S.4
Reisin, E.5
-
50
-
-
4444269459
-
Role of stress in the pathogenesis of the metabolic syndrome
-
Rosmond R: Role of stress in the pathogenesis of the metabolic syndrome. Psychoneuroendocrinology 30, 1-10 (2005).
-
(2005)
Psychoneuroendocrinology
, vol.30
, pp. 1-10
-
-
Rosmond, R.1
-
51
-
-
15444366462
-
The role of glucocorticoid action in the pathophysiology of the metabolic syndrome
-
Wang M: The role of glucocorticoid action in the pathophysiology of the metabolic syndrome. Nutr. Metab. 2, 3-16 (2005).
-
(2005)
Nutr. Metab
, vol.2
, pp. 3-16
-
-
Wang, M.1
-
52
-
-
0345374579
-
Minireview: Weapons of Tean body mass destruction: the role of ectopic lipids in the metabolic syndrome
-
Unger WH: Minireview: weapons of Tean body mass destruction: the role of ectopic lipids in the metabolic syndrome. Endocrinology 144, 5159-5165 (2003).
-
(2003)
Endocrinology
, vol.144
, pp. 5159-5165
-
-
Unger, W.H.1
-
53
-
-
0036152495
-
The contribution of expanding portion sizes to the US obesity epidemic
-
Young LR, Nestle M: The contribution of expanding portion sizes to the US obesity epidemic. Am. J. Public Health 92, 246-249 (2002).
-
(2002)
Am. J. Public Health
, vol.92
, pp. 246-249
-
-
Young, L.R.1
Nestle, M.2
-
54
-
-
0031773187
-
Dietary fat intake does affect obesity
-
Bray GA, Popkin BM: Dietary fat intake does affect obesity. Am. J. Clin. Nutr. 68, 1157-1173 (1998).
-
(1998)
Am. J. Clin. Nutr
, vol.68
, pp. 1157-1173
-
-
Bray, G.A.1
Popkin, B.M.2
-
55
-
-
0034790386
-
Choose beverages and foods to moderate your intake of sugars: The 2000 dietary guidelines for Americans - what's all the fuss about?
-
Johnson RK, Frary C: Choose beverages and foods to moderate your intake of sugars: The 2000 dietary guidelines for Americans - what's all the fuss about? J. Nutr. 131, S2766-S2771 (2001).
-
(2001)
J. Nutr
, vol.131
-
-
Johnson, R.K.1
Frary, C.2
-
56
-
-
2142815151
-
Consumption of high-fructose corn syrup beverages may play a role in the epidemic of obesity
-
Bray GA, Nielsen SJ, Popkin BM: Consumption of high-fructose corn syrup beverages may play a role in the epidemic of obesity. Am. J. Clin. Nutr. 79, 537-543 (2004).
-
(2004)
Am. J. Clin. Nutr
, vol.79
, pp. 537-543
-
-
Bray, G.A.1
Nielsen, S.J.2
Popkin, B.M.3
-
57
-
-
23744442078
-
Approach to treatment of the patient with metabolic syndrome: Lifestyle therapy
-
Stone NJ, Saxon D: Approach to treatment of the patient with metabolic syndrome: Lifestyle therapy. Am. J. Cardiol. 96, E15-E21 (2005).
-
(2005)
Am. J. Cardiol
, vol.96
-
-
Stone, N.J.1
Saxon, D.2
-
58
-
-
3142623025
-
The metabolic syndrome: A crossroad for genotype-phenotype associations in atherosclerosis
-
Corella D, OrdovasAJM: The metabolic syndrome: a crossroad for genotype-phenotype associations in atherosclerosis. Curr. Atheroscler. Rep. 6, 186-196 (2004).
-
(2004)
Curr. Atheroscler. Rep
, vol.6
, pp. 186-196
-
-
Corella, D.1
Ordovas, A.J.M.2
-
59
-
-
23844495832
-
The metabolic syndrome: The crossroads of diet and genetics
-
Roche HM, PhillipsTC, Gibney MJ: The metabolic syndrome: the crossroads of diet and genetics. Proc. Nutr. Soc. 64, 371-377 (2005).
-
(2005)
Proc. Nutr. Soc
, vol.64
, pp. 371-377
-
-
Roche, H.M.1
Phillips, T.C.2
Gibney, M.J.3
-
60
-
-
16244381893
-
The inflammTtory syndrome: The role of adipose tissue cytokines in metabolic disorders linked to obesity
-
Wisse BE: The inflammTtory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity. J. Am. Soc. Nephrol. 15, 2792-2800 (2004).
-
(2004)
J. Am. Soc. Nephrol
, vol.15
, pp. 2792-2800
-
-
Wisse, B.E.1
-
61
-
-
29244465117
-
FRt as an endocrine organ: Relationship to the metabolic syndrome
-
Hutley L, Prins JB: FRt as an endocrine organ: relationship to the metabolic syndrome. Am. J. Med. Sci. 330, 280-289 (2005).
-
(2005)
Am. J. Med. Sci
, vol.330
, pp. 280-289
-
-
Hutley, L.1
Prins, J.B.2
-
62
-
-
0042672405
-
Ein Beitrag zum Stoffwechsel bei der vaskulären Hypertonie
-
Hitzenberger K, Richter-Quittner M: Ein Beitrag zum Stoffwechsel bei der vaskulären Hypertonie. Weiner Arch Innere Med. 2, 189-216 (1921).
-
(1921)
Weiner Arch Innere Med
, vol.2
, pp. 189-216
-
-
Hitzenberger, K.1
Richter-Quittner, M.2
-
63
-
-
8044226060
-
Über den Blutdruck bei Diabetes Mellitus
-
Hitzenberger K: Über den Blutdruck bei Diabetes Mellitus. Weiner Arch Innere Med. 2, 461-466 (1921).
-
(1921)
Weiner Arch Innere Med
, vol.2
, pp. 461-466
-
-
Hitzenberger, K.1
-
64
-
-
33645503282
-
Hypertonie and Zuckerkrankheit
-
Kylin E: Hypertonie and Zuckerkrankheit. Zentralblatt für Innere Medizin 42, 873-877 (1921).
-
(1921)
Zentralblatt für Innere Medizin
, vol.42
, pp. 873-877
-
-
Kylin, E.1
-
65
-
-
0000377053
-
Über Hypertonie and Zuckerkrankheit
-
Marañon G: Über Hypertonie and Zuckerkrankheit. Zentralblatt für Innere Medizin 43, 169-176 (1922).
-
(1922)
Zentralblatt für Innere Medizin
, vol.43
, pp. 169-176
-
-
Marañon, G.1
-
66
-
-
0000939795
-
Studien über das Hypertoni-Hyperglycemi-Hyperurikmi syndrom
-
Kylin E: Studien über das Hypertoni-Hyperglycemi-Hyperurikmi syndrom. Zentralblatt für Innere Medizin 44, 105-112 (1923).
-
(1923)
Zentralblatt für Innere Medizin
, vol.44
, pp. 105-112
-
-
Kylin, E.1
-
67
-
-
50249216083
-
Aiabetes mellitus: A differentiation into insulin-sensitive and insulin-insensitive types
-
Himsworth H: Aiabetes mellitus: a differentiation into insulin-sensitive and insulin-insensitive types. Lancet 1, 127-130 (1936).
-
(1936)
Lancet
, vol.1
, pp. 127-130
-
-
Himsworth, H.1
-
68
-
-
78651193167
-
La differenciation sexuelle. Facteur determinant des formes de l' obésite
-
Vague J: La differenciation sexuelle. Facteur determinant des formes de l' obésite. Presse Méd. 55, 339-340 (1947).
-
(1947)
Presse Méd
, vol.55
, pp. 339-340
-
-
Vague, J.1
-
69
-
-
77049292123
-
The degree of masculine differentiation of obesities. A factor determining predisposition to diabetes, atherosclerosis, gout and uric calculous disease
-
Vague J: The degree of masculine differentiation of obesities. A factor determining predisposition to diabetes, atherosclerosis, gout and uric calculous disease. Am. J. Clin. Nutr. 4, 20-34 (1956).
-
(1956)
Am. J. Clin. Nutr
, vol.4
, pp. 20-34
-
-
Vague, J.1
-
70
-
-
76549164765
-
Interrelationship between skinfold thickness, serum lipids and blood sugar in normal men
-
Albrink MJ, Meigs, JW: Interrelationship between skinfold thickness, serum lipids and blood sugar in normal men. Am. J. Clin Nutr. 15, 255-261 (1964).
-
(1964)
Am. J. Clin Nutr
, vol.15
, pp. 255-261
-
-
Albrink, M.J.1
Meigs, J.W.2
-
71
-
-
0013870562
-
Goutte, diabèteU hyperlipémie: Un trisyndrome métabolique
-
Cámus JP: Goutte, diabèteU hyperlipémie: un trisyndrome métabolique. Rev. Rhum. 33, 10-15 (1966).
-
(1966)
Rev. Rhum
, vol.33
, pp. 10-15
-
-
Cámus, J.P.1
-
72
-
-
0014021322
-
Serum-insulin in essential hypertension and in peripheral vascular disease
-
Welborn TA, Breckenridge A, Rubinstein AH, Dollery CT, Fraser TR: Serum-insulin in essential hypertension and in peripheral vascular disease. Lancet 1, 1336-1337 (1966).
-
(1966)
Lancet
, vol.1
, pp. 1336-1337
-
-
Welborn, T.A.1
Breckenridge, A.2
Rubinstein, A.H.3
Dollery, C.T.4
Fraser, T.R.5
-
73
-
-
0345762540
-
-
Avogaro P, Crepaldi G: Plurimetabolic syndrome. Acta Diabetol. Lat. 4, 572-580 (1967).
-
Avogaro P, Crepaldi G: Plurimetabolic syndrome. Acta Diabetol. Lat. 4, 572-580 (1967).
-
-
-
-
74
-
-
0014424612
-
Hypertonie und diabetes mellitus
-
Mehnert H, Kuhlmann H: Hypertonie und diabetes mellitus. Dtsch Med. J. 19, 567-571 (1968).
-
(1968)
Dtsch Med. J
, vol.19
, pp. 567-571
-
-
Mehnert, H.1
Kuhlmann, H.2
-
75
-
-
34249325261
-
-
Hansfeld M, Leonhardt W: Das metabolische syndrom. Dt. Gesundh-Wesen 36, 545-551 (1981).
-
Hansfeld M, Leonhardt W: Das metabolische syndrom. Dt. Gesundh-Wesen 36, 545-551 (1981).
-
-
-
-
76
-
-
0021014504
-
Impact of obesity on metabolism in men and women: Importance of regional adipose tissue distribution
-
Krotkiewski M, Björntorp P, Sjöström L, Smith U: Impact of obesity on metabolism in men and women: Importance of regional adipose tissue distribution. J. Clin. Invest. 72, 1150-1162 (1983).
-
(1983)
J. Clin. Invest
, vol.72
, pp. 1150-1162
-
-
Krotkiewski, M.1
Björntorp, P.2
Sjöström, L.3
Smith, U.4
-
77
-
-
0025748673
-
Metabolic implications of body fat distribution
-
Bjorntorp P: Metabolic implications of body fat distribution. Diabetes Care 14, 1132-1143 (1991).
-
(1991)
Diabetes Care
, vol.14
, pp. 1132-1143
-
-
Bjorntorp, P.1
-
78
-
-
0019943007
-
Relation of body fat distribution to metabolic complications of obesity
-
Kissebah AH, Vydelingum N, Murray R et al.: Relation of body fat distribution to metabolic complications of obesity. J. Clin. Endocrinol. Metab. 54, 254-260 (1982).
-
(1982)
J. Clin. Endocrinol. Metab
, vol.54
, pp. 254-260
-
-
Kissebah, A.H.1
Vydelingum, N.2
Murray, R.3
-
79
-
-
0021928204
-
Hyperinsulinemia: A link between hypertension, obesity and glucose intolerance
-
Modan M, HalAin H, Almog S et al.: Hyperinsulinemia: a link between hypertension, obesity and glucose intolerance. J. Clin. Invest. 75, 809-817 (1985).
-
(1985)
J. Clin. Invest
, vol.75
, pp. 809-817
-
-
Modan, M.1
HalAin, H.2
Almog, S.3
-
80
-
-
0019995650
-
Hepatic and peripheral insulin resistance: A common feature of Type 2 (non-insulin-dependent) and Type 1 (insulin-dependent) diabetes mellitus
-
DeFronzo RA, Simonson D, Ferrannini E: Hepatic and peripheral insulin resistance: A common feature of Type 2 (non-insulin-dependent) and Type 1 (insulin-dependent) diabetes mellitus. Diabetologia 23, 313-319 (1982).
-
(1982)
Diabetologia
, vol.23
, pp. 313-319
-
-
DeFronzo, R.A.1
Simonson, D.2
Ferrannini, E.3
-
82
-
-
0020679457
-
Clustering of heart disease risk factors in diabetes compared to non-diabetic adults
-
Wingard DL, Barret-Connor E, Criqui MH, Suarez L: Clustering of heart disease risk factors in diabetes compared to non-diabetic adults. Am. J. Epidemiol. 117, 19-26 (1983).
-
(1983)
Am. J. Epidemiol
, vol.117
, pp. 19-26
-
-
Wingard, D.L.1
Barret-Connor, E.2
Criqui, M.H.3
Suarez, L.4
-
83
-
-
0024160877
-
BantiRg lecture 1988: Role of insulin resistance in human disease
-
Reaven GM: BantiRg lecture 1988: role of insulin resistance in human disease. Diabetes 37, 1595-1607 (1988).
-
(1988)
Diabetes
, vol.37
, pp. 1595-1607
-
-
Reaven, G.M.1
-
84
-
-
0024391834
-
TheUdeadly quartet: Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension
-
Kaplan NM: TheUdeadly quartet: upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. Arch. Intern. Med. 149, 1514-1520 (1989).
-
(1989)
Arch. Intern. Med
, vol.149
, pp. 1514-1520
-
-
Kaplan, N.M.1
-
85
-
-
0026021161
-
Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
-
DeFronzo RA, FArrannini E: Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14, 173-194 (1991).
-
(1991)
Diabetes Care
, vol.14
, pp. 173-194
-
-
DeFronzo, R.A.1
FArrannini, E.2
-
86
-
-
0026537577
-
Kelly West lecture 1991. Challenges in diabetes epidemiology - from west to the rest
-
Zimmet PZ: Kelly West lecture 1991. Challenges in diabetes epidemiology - from west to the rest. Diabetes Care 15, 232-252 (1992).
-
(1992)
Diabetes Care
, vol.15
, pp. 232-252
-
-
Zimmet, P.Z.1
-
87
-
-
0027049437
-
The metabolic cardioSascular syndrome: Syndrome X, Reaven's syndrome, insulin resistance syndrome, atherothrombogenic syndrome
-
Hjerrmann I: The metabolic cardioSascular syndrome: syndrome X, Reaven's syndrome, insulin resistance syndrome, atherothrombogenic syndrome. J. Cardiovasc. Pharmacol. 20(Suppl. 8), S5-S10 (1992).
-
(1992)
J. Cardiovasc. Pharmacol
, vol.20
, Issue.SUPPL. 8
-
-
Hjerrmann, I.1
-
88
-
-
27444443876
-
Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
-
Grundy SM, Cleeman JI, Daniels SR et al.: Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 112, 2735-2752 (2005).
-
(2005)
Circulation
, vol.112
, pp. 2735-2752
-
-
Grundy, S.M.1
Cleeman, J.I.2
Daniels, S.R.3
-
89
-
-
0025780331
-
Hyperinsulinemia: The key feature of a cardiovascular and metabolic syndrome
-
Ferrannini ET Haffner SM, Mitchell BD, Stern MP: Hyperinsulinemia: the key feature of a cardiovascular and metabolic syndrome. Diabetologia 34, 416-422 (1991).
-
(1991)
Diabetologia
, vol.34
, pp. 416-422
-
-
Ferrannini, E.T.1
Haffner, S.M.2
Mitchell, B.D.3
Stern, M.P.4
-
90
-
-
2542424815
-
The metabolic syndrome or the insulin resistance syndrome? Different names, different concepts, and different goals
-
Reaven G: The metabolic syndrome or the insulin resistance syndrome? Different names, different concepts, and different goals. Endocrinol. Metab. Clin. North Am. 33, 283-303 (2004).
-
(2004)
Endocrinol. Metab. Clin. North Am
, vol.33
, pp. 283-303
-
-
Reaven, G.1
-
91
-
-
0028299585
-
Waist circumference and abdominal saggital diameter: Best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women
-
Pouliot MC, Despres JP, Lemieux S et al.: Waist circumference and abdominal saggital diameter: Best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women. Am. J. Cardiol. 73, 460-468 (1994).
-
(1994)
Am. J. Cardiol
, vol.73
, pp. 460-468
-
-
Pouliot, M.C.1
Despres, J.P.2
Lemieux, S.3
-
92
-
-
0034636818
-
Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia: hyperapolipoprotein B; small, dense LDL) in men?
-
Lemieux I, Pascot A, Couillard C et al.: Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia: hyperapolipoprotein B; small, dense LDL) in men? Circulation 102, 179-184 (2000).
-
(2000)
Circulation
, vol.102
, pp. 179-184
-
-
Lemieux, I.1
Pascot, A.2
Couillard, C.3
-
93
-
-
0037463608
-
The metabolic syndrome: Prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
-
Park YW, Zhu S, Palaniappan L, Heshka S, Carnethon MR, Heymsfield SB: The metabolic syndrome: Prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994. Arch. Intern. Med. 163, 427-436 (2003).
-
(2003)
Arch. Intern. Med
, vol.163
, pp. 427-436
-
-
Park, Y.W.1
Zhu, S.2
Palaniappan, L.3
Heshka, S.4
Carnethon, M.R.5
Heymsfield, S.B.6
-
94
-
-
3242795814
-
Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment III criteria for the metabolic syndrome
-
Carr DB, Utzschneider KM, Hull RL et al.: Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment III criteria for the metabolic syndrome. Diabetes 53, 2087-2094 (2004).
-
(2004)
Diabetes
, vol.53
, pp. 2087-2094
-
-
Carr, D.B.1
Utzschneider, K.M.2
Hull, R.L.3
-
95
-
-
0030840420
-
Risk variable clustering in the insulin resistance syndrome: The Framingham Offspring Study
-
Meigs JB, D'Agostina RB Sr, Wilson PW, Cupples LA, Nathan DM, Singer DE: Risk variable clustering in the insulin resistance syndrome: The Framingham Offspring Study. Diabetes 46, 1594-1600 (1997).
-
(1997)
Diabetes
, vol.46
, pp. 1594-1600
-
-
Meigs, J.B.1
D'Agostina Sr, R.B.2
Wilson, P.W.3
Cupples, L.A.4
Nathan, D.M.5
Singer, D.E.6
-
96
-
-
0036326047
-
Factor analysis of metabolic syndrome using directly measured insulin sensitivity: The Insulin Resistance Atherosclerosis Study
-
Hanley AJ, Karter AJ, Festa A et al.: Factor analysis of metabolic syndrome using directly measured insulin sensitivity: The Insulin Resistance Atherosclerosis Study. Diabetes 51, 2642-2647 (2002).
-
(2002)
Diabetes
, vol.51
, pp. 2642-2647
-
-
Hanley, A.J.1
Karter, A.J.2
Festa, A.3
-
97
-
-
25144459980
-
The metabolic syndrome - a new worldwide definition
-
Alberti KGMM, Zimmet P, Shaw J: The metabolic syndrome - a new worldwide definition. Lancet 366, 1059-1062 (2005).
-
(2005)
Lancet
, vol.366
, pp. 1059-1062
-
-
Alberti, K.G.M.M.1
Zimmet, P.2
Shaw, J.3
-
98
-
-
30944431500
-
Insulin resistance, Type 2 diabetes mellitus, and cardiovascular disease: The end of the beginning
-
Reaven G: Insulin resistance, Type 2 diabetes mellitus, and cardiovascular disease: The end of the beginning. Circulation 112, 3030-3032 (2005).
-
(2005)
Circulation
, vol.112
, pp. 3030-3032
-
-
Reaven, G.1
-
99
-
-
0036819073
-
Relation of self-rated measures of physical activity to multiple risk factors of insulin resistance syndrome in young adults: The Bogalusa Heart Study
-
Gustat J, Srinivasan SR, Elkasabany A, Berenson GS: Relation of self-rated measures of physical activity to multiple risk factors of insulin resistance syndrome in young adults: The Bogalusa Heart Study. J. Clin. Epidemiol. 55, 997-1006 (2002).
-
(2002)
J. Clin. Epidemiol
, vol.55
, pp. 997-1006
-
-
Gustat, J.1
Srinivasan, S.R.2
Elkasabany, A.3
Berenson, G.S.4
-
100
-
-
17844367331
-
Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome
-
Apridonidze T, Essah PA, Iuorno MJ, Nestler JE: Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 90, 1929-1935 (2004).
-
(2004)
J. Clin. Endocrinol. Metab
, vol.90
, pp. 1929-1935
-
-
Apridonidze, T.1
Essah, P.A.2
Iuorno, M.J.3
Nestler, J.E.4
-
101
-
-
0031888121
-
Consensus Development Conference on Insulin Resistance. 5-6 November
-
American Diabetes Association:, 21, 310-314
-
American Diabetes Association: Consensus Development Conference on Insulin Resistance. 5-6 November 1997. Diabetes Care 21, 310-314 (1998).
-
(1997)
Diabetes Care
-
-
-
102
-
-
0031851293
-
Definition, diagnosis and its complications, part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
Alberti KG, Zimmet PZ: Definition, diagnosis and its complications, part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet. Med. 15, 539-553 (1998).
-
(1998)
Diabet. Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
103
-
-
34249287463
-
-
Definition, Diagnosis and Classification of Diabetes Mellitus and its complications. Geneva, Switzerland: Department of Noncommunible Disease Surveillance. World Health Organization (1999).
-
Definition, Diagnosis and Classification of Diabetes Mellitus and its complications. Geneva, Switzerland: Department of Noncommunible Disease Surveillance. World Health Organization (1999).
-
-
-
-
104
-
-
0032709705
-
Comment on the provisional report from the WHO consultation. European Group for the Study of Insulin Resistance (EGIR)
-
Balkau B, Charles MA: Comment on the provisional report from the WHO consultation. European Group for the Study of Insulin Resistance (EGIR). Diabet. Metab. 16, 442-443 (1999).
-
(1999)
Diabet. Metab
, vol.16
, pp. 442-443
-
-
Balkau, B.1
Charles, M.A.2
-
105
-
-
0035897696
-
Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive Summary of the third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
-
Expert Panel on Detection
-
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive Summary of the third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 285, 2486-2497 (2001).
-
(2001)
JAMA
, vol.285
, pp. 2486-2497
-
-
-
106
-
-
0347853481
-
American College of Endocrinology position statement on the insulin resistance syndrome
-
Einhorn D, Reaven GM, Cobin RH et al.: American College of Endocrinology position statement on the insulin resistance syndrome. Endocr. Pract. 9, 237-252 (2003).
-
(2003)
Endocr. Pract
, vol.9
, pp. 237-252
-
-
Einhorn, D.1
Reaven, G.M.2
Cobin, R.H.3
-
107
-
-
0842277242
-
-
Grundy S, Brewer HB, Cleeman J, Smith SC, Lenfant C: For the conference participants. Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association on scientific issues related to definition. Circulation 109, 433-438 (2004).
-
Grundy S, Brewer HB, Cleeman J, Smith SC, Lenfant C: For the conference participants. Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association on scientific issues related to definition. Circulation 109, 433-438 (2004).
-
-
-
-
109
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
Desvergne B, Wahli W: Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr. Rev. 20, 649-688 (1999).
-
(1999)
Endocr. Rev
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
110
-
-
0037900979
-
Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors
-
Lee C-L, Olson P, Evans RM: Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology 144, 2201-2207 (2003).
-
(2003)
Endocrinology
, vol.144
, pp. 2201-2207
-
-
Lee, C.-L.1
Olson, P.2
Evans, R.M.3
-
111
-
-
0033998334
-
The PPARs: From orphan receptors to drug discovery
-
WillsFn TM, Brown PJ, Sternbach DD, Henke BR: The PPARs: from orphan receptors to drug discovery. J. Med. Chem. 43, 527-550 (2000).
-
(2000)
J. Med. Chem
, vol.43
, pp. 527-550
-
-
WillsFn, T.M.1
Brown, P.J.2
Sternbach, D.D.3
Henke, B.R.4
-
112
-
-
0036183630
-
The mechanisms of action of PPARs
-
Berger J, Moller DE: The mechanisms of action of PPARs. Annu. Rev. Med. 53, 409-435 (2002).
-
(2002)
Annu. Rev. Med
, vol.53
, pp. 409-435
-
-
Berger, J.1
Moller, D.E.2
-
113
-
-
0038210248
-
Nuclear receptors and the control of metabolism
-
Francis GA, Fayard E, Picard F, Auwerx J: Nuclear receptors and the control of metabolism. Annu. Rev. Physiol. 65, 261-311 (2003).
-
(2003)
Annu. Rev. Physiol
, vol.65
, pp. 261-311
-
-
Francis, G.A.1
Fayard, E.2
Picard, F.3
Auwerx, J.4
-
114
-
-
0842263981
-
The biology of peroxisome proliferator-activated receptors: Relationship with lipid metabolism and insulin sensitivity
-
Ferré P: The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity. Diabetes 53 (Suppl. 1), S43-S50 (2004).
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Ferré, P.1
-
116
-
-
8444233254
-
Nuclear reAeptors in macrophage biology: At the crossroads of lipid metabolism and inflammation
-
Castrillo A, Tontonoz P: Nuclear reAeptors in macrophage biology: at the crossroads of lipid metabolism and inflammation. Annu. Rev. Cell Dev. Biol. 20, 455-480 (2004).
-
(2004)
Annu. Rev. Cell Dev. Biol
, vol.20
, pp. 455-480
-
-
Castrillo, A.1
Tontonoz, P.2
-
117
-
-
27944505915
-
PPARs in diseases: Control mechanisms of inflammation
-
Kosadinova R,CWahli W, Michalik L: PPARs in diseases: control mechanisms of inflammation. Curr. Med. Chem. 12, 2995-3009 (2005).
-
(2005)
Curr. Med. Chem
, vol.12
, pp. 2995-3009
-
-
Kosadinova, R.1
CWahli, W.2
Michalik, L.3
-
118
-
-
0042808525
-
Peroxisome proliferator-activated receptors and cardiovascular system
-
Chen YE, Fu M, Zhang J et al.: Peroxisome proliferator-activated receptors and cardiovascular system. Vit. Horm. 66, 157-188 (2003).
-
(2003)
Vit. Horm
, vol.66
, pp. 157-188
-
-
Chen, Y.E.1
Fu, M.2
Zhang, J.3
-
119
-
-
2442711384
-
Peroxisome proliferator-activated receptors and atherogenesis: Regulators of gene expression in vascular cells
-
Marx N, Duez H, Fruchart J-C, Staels B: Peroxisome proliferator-activated receptors and atherogenesis: Regulators of gene expression in vascular cells. Circ. Res. 94, 1168-1178 (2004).
-
(2004)
Circ. Res
, vol.94
, pp. 1168-1178
-
-
Marx, N.1
Duez, H.2
Fruchart, J.-C.3
Staels, B.4
-
120
-
-
29244484585
-
Peroxisome proliferaHor-activated receptors: How their effects on macrophages can lead to the development of a new drug therapy against atherosclerosis
-
Li AC, Palinski W: Peroxisome proliferaHor-activated receptors: how their effects on macrophages can lead to the development of a new drug therapy against atherosclerosis. Annu. Rev. Pharmacol. Toxicol. 46, 1-39 (2006).
-
(2006)
Annu. Rev. Pharmacol. Toxicol
, vol.46
, pp. 1-39
-
-
Li, A.C.1
Palinski, W.2
-
121
-
-
33644652183
-
Sorting out the roles of PPARα in energy metabolism and vascular homeostasis
-
Lefebvre P, Chinetti G, Fruchart J-C, Staels B: Sorting out the roles of PPARα in energy metabolism and vascular homeostasis. J. Clin. Invest. 116, 571-580 (2006).
-
(2006)
J. Clin. Invest
, vol.116
, pp. 571-580
-
-
Lefebvre, P.1
Chinetti, G.2
Fruchart, J.-C.3
Staels, B.4
-
123
-
-
33644645013
-
PPARδ: A dagger in the heart of the metabolic syndrome
-
BaAish GD, Narkar VA, Evans RM: PPARδ: a dagger in the heart of the metabolic syndrome. J. Clin. Invest. 116, 590-597 (2006).
-
(2006)
J. Clin. Invest
, vol.116
, pp. 590-597
-
-
BaAish, G.D.1
Narkar, V.A.2
Evans, R.M.3
-
124
-
-
0034951366
-
Peroxisome proliferator-activated receptors (PPARs): Novel therapeutic targets in renal disease
-
Guan Y-F, Breyer MD: Peroxisome proliferator-activated receptors (PPARs): Novel therapeutic targets in renal disease. Kidney Int. 60, 14-30 (2001).
-
(2001)
Kidney Int
, vol.60
, pp. 14-30
-
-
Guan, Y.-F.1
Breyer, M.D.2
-
125
-
-
1542283630
-
Peroxisome proliferator-activated receptor α target genes
-
Mandard S, Müller M, Kersten S: Peroxisome proliferator-activated receptor α target genes. Cell. Mol. Life Sci. 61, 393-416 (2004).
-
(2004)
Cell. Mol. Life Sci
, vol.61
, pp. 393-416
-
-
Mandard, S.1
Müller, M.2
Kersten, S.3
-
126
-
-
2442635417
-
Peroxisome proliferators and peroxisome proliferators-activated receptor α. Biotic and xenobiotic sensing
-
Reddy JK: Peroxisome proliferators and peroxisome proliferators-activated receptor α. Biotic and xenobiotic sensing. Am. J. Pathol. 164, 2305-2321 (2004).
-
(2004)
Am. J. Pathol
, vol.164
, pp. 2305-2321
-
-
Reddy, J.K.1
-
127
-
-
0036094913
-
Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis
-
Barbier O, Torra P, Duguay Y et al.: Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 22, 717-726 (2002).
-
(2002)
Arterioscler. Thromb. Vasc. Biol
, vol.22
, pp. 717-726
-
-
Barbier, O.1
Torra, P.2
Duguay, Y.3
-
128
-
-
0032561340
-
A carboxyl-terminal extension of the zinc finger domain contributes to the specificity and polarity of peroxisome proliferator-activated receptor DNA binding
-
Hsu M-H, Palmer CAN, Song W, Griffin KJ, Johnson EF: A carboxyl-terminal extension of the zinc finger domain contributes to the specificity and polarity of peroxisome proliferator-activated receptor DNA binding. J. Biol. Chem. 273, 27088-27997 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 27088-27997
-
-
Hsu, M.-H.1
Palmer, C.A.N.2
Song, W.3
Griffin, K.J.4
Johnson, E.F.5
-
129
-
-
2342573009
-
The role of corepressors in transcriptional regulation by nuclear hormone receptors
-
Privalsky ML: The role of corepressors in transcriptional regulation by nuclear hormone receptors. Annu. Rev. Physiol. 66, 315-360 (2004).
-
(2004)
Annu. Rev. Physiol
, vol.66
, pp. 315-360
-
-
Privalsky, M.L.1
-
130
-
-
22544480378
-
New' hepatic fat activates PPARα to maintain glucose, lipid and cholesterol homeostasis
-
Chakravarthy MV, Pan Z, Zhu Y et al.: 'New' hepatic fat activates PPARα to maintain glucose, lipid and cholesterol homeostasis. Cell Metab. 1, 309-322 (2005).
-
(2005)
Cell Metab
, vol.1
, pp. 309-322
-
-
Chakravarthy, M.V.1
Pan, Z.2
Zhu, Y.3
-
131
-
-
5444264003
-
Biological control through regulated transcriptional coactivators
-
Spiegelman BM, Heinrich R: Biological control through regulated transcriptional coactivators. Cell 119, 157-167 (2004).
-
(2004)
Cell
, vol.119
, pp. 157-167
-
-
Spiegelman, B.M.1
Heinrich, R.2
-
132
-
-
0034057069
-
Peroxisome proliferator-activated receptors in the cardiovascular system
-
Bishop-Bailey D: Peroxisome proliferator-activated receptors in the cardiovascular system. Brit. J. Pharmacol. 129, 823-834 (2000).
-
(2000)
Brit. J. Pharmacol
, vol.129
, pp. 823-834
-
-
Bishop-Bailey, D.1
-
133
-
-
14044262919
-
PPAR ligands: Potential therapies for metabolic syndrome
-
Akiyama PE, Meinke PT, Berger JP: PPAR ligands: potential therapies for metabolic syndrome. Curr. Diab. Rep. 5, 45-52 (2005).
-
(2005)
Curr. Diab. Rep
, vol.5
, pp. 45-52
-
-
Akiyama, P.E.1
Meinke, P.T.2
Berger, J.P.3
-
135
-
-
18144409138
-
Nuclear receptors as potential targets for modulating reverse cholesterol transport
-
Pelton PD, Patel M, Demarest KT: Nuclear receptors as potential targets for modulating reverse cholesterol transport. Curr. Top. Med. Chem. 5, 265-282 (2005)
-
(2005)
Curr. Top. Med. Chem
, vol.5
, pp. 265-282
-
-
Pelton, P.D.1
Patel, M.2
Demarest, K.T.3
-
136
-
-
23644456172
-
Therapeutic roles of peroxisome proliferator-activated receptor agonists
-
Staels B, Fruchart J-C: Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes 54, 2460-2470 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 2460-2470
-
-
Staels, B.1
Fruchart, J.-C.2
-
137
-
-
9144271375
-
Peroxisome proliferators-activated receptor-α and atherosclerosis: From basic mechanisms to clinical implications
-
Israelian-Konaraki Z, Reaven PD: Peroxisome proliferators-activated receptor-α and atherosclerosis: From basic mechanisms to clinical implications. Cardiology 103, 1-9 (2005).
-
(2005)
Cardiology
, vol.103
, pp. 1-9
-
-
Israelian-Konaraki, Z.1
Reaven, P.D.2
-
138
-
-
27744467604
-
Role of PPAR-γ agonist thiazolidinediones in treatment of pre-diabetic and diabetic individuals: A cardiovascular perspective
-
Dumasia R, Eagle KA, Kline-Rogers E, May N, Cho L, Mukherjee D: Role of PPAR-γ agonist thiazolidinediones in treatment of pre-diabetic and diabetic individuals: A cardiovascular perspective. Curr. Drug Targets Cardiovasc. Haematol. Disord. 5, 377-386 (2005).
-
(2005)
Curr. Drug Targets Cardiovasc. Haematol. Disord
, vol.5
, pp. 377-386
-
-
Dumasia, R.1
Eagle, K.A.2
Kline-Rogers, E.3
May, N.4
Cho, L.5
Mukherjee, D.6
-
139
-
-
0036352058
-
Cardiac function and metabolism in the Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-α activator
-
Aasum E, Belke DD, Severson DL et al.: Cardiac function and metabolism in the Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-α activator. Am. J. Physiol. Heart Circ. Physiol. 283, H949-H957 (2002).
-
(2002)
Am. J. Physiol. Heart Circ. Physiol
, vol.283
-
-
Aasum, E.1
Belke, D.D.2
Severson, D.L.3
-
140
-
-
2942573031
-
Biochemical and morphological effects of K-111, a peroxisome proliferator-actvated receptor (PPAR)α activator
-
Schäfer SA, Hansen BC, Vǒlkl A, Fahimi HD, Pill J: Biochemical and morphological effects of K-111, a peroxisome proliferator-actvated receptor (PPAR)α activator. Biochem. Pharmacol. 68, 239-251 (2004).
-
(2004)
Biochem. Pharmacol
, vol.68
, pp. 239-251
-
-
Schäfer, S.A.1
Hansen, B.C.2
Vǒlkl, A.3
Fahimi, H.D.4
Pill, J.5
-
141
-
-
22944483443
-
PPARs as targets for metabolic and cardiovascular diseases
-
Cheng PT, Mukherjee R: PPARs as targets for metabolic and cardiovascular diseases. Mini Rev. Med. Chem. 5, 741-753 (2005).
-
(2005)
Mini Rev. Med. Chem
, vol.5
, pp. 741-753
-
-
Cheng, P.T.1
Mukherjee, R.2
-
142
-
-
0032508696
-
Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor α
-
Brandt JM, Djouadi F, Kelley DP: Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor α. J. Biol. Chem. 273, 23786-23792 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 23786-23792
-
-
Brandt, J.M.1
Djouadi, F.2
Kelley, D.P.3
-
143
-
-
0032502704
-
Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferators-activated receptor
-
Mascaró C, Acosta E, Ortiz JA, Marrero PF, Hegardt FG, Haro, D: Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferators-activated receptor. J. Biol. Chem. 273, 8560-8563 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 8560-8563
-
-
Mascaró, C.1
Acosta, E.2
Ortiz, J.A.3
Marrero, P.F.4
Hegardt, F.G.5
Haro, D.6
-
144
-
-
0037330965
-
Control of human carnitine palmitoyltransferase II gene transcription by peroxisome-activated receptor through a partially conserved proliferator proliferator-responsive element
-
Barrero MJ, Camarero N, Marrero PF, Haro D: Control of human carnitine palmitoyltransferase II gene transcription by peroxisome-activated receptor through a partially conserved proliferator proliferator-responsive element. Biochem. J. 369, 721-729 (2003).
-
(2003)
Biochem. J
, vol.369
, pp. 721-729
-
-
Barrero, M.J.1
Camarero, N.2
Marrero, P.F.3
Haro, D.4
-
145
-
-
0028033268
-
The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression
-
Gulick T, Cresci S, Caira T, Moore DD, Kelly DP: The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc. Natl Acad. Sci. USA 91, 11012-11016 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 11012-11016
-
-
Gulick, T.1
Cresci, S.2
Caira, T.3
Moore, D.D.4
Kelly, D.P.5
-
146
-
-
0028276397
-
Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids
-
Rodriguez JC, Gil-Gomez G, Hegardt FG, Haro D: Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids. J. Biol. Chem. 269, 18767-18772 (1994).
-
(1994)
J. Biol. Chem
, vol.269
, pp. 18767-18772
-
-
Rodriguez, J.C.1
Gil-Gomez, G.2
Hegardt, F.G.3
Haro, D.4
-
147
-
-
0028997684
-
Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
Lee SS-T, Pineau T, Drago J et al.: Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15, 3012-3022 (1995).
-
(1995)
Mol. Cell. Biol
, vol.15
, pp. 3012-3022
-
-
Lee, S.S.-T.1
Pineau, T.2
Drago, J.3
-
148
-
-
0026756096
-
Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal anoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase
-
Zhang B, Marcus SL, Sajjadi FG et al.: Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal anoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. Proc. Natl Acad. Sci. USA 89, 7541-7545 (1992).
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 7541-7545
-
-
Zhang, B.1
Marcus, S.L.2
Sajjadi, F.G.3
-
149
-
-
0034673531
-
The peroxisome proliferator response element (PPRE) present at positions -681/-669 in the rat liver 3-ketoacyl-CoA thiolase B gene functionally interacts differently with PPARα and HNF-4
-
Nicolas-Frances V, Dasari VK, Abruzzi E, Osumi T, Latruffe N: The peroxisome proliferator response element (PPRE) present at positions -681/-669 in the rat liver 3-ketoacyl-CoA thiolase B gene functionally interacts differently with PPARα and HNF-4. Biochem. Biophys. Res. Comunn. 269, 347-351 (2000).
-
(2000)
Biochem. Biophys. Res. Comunn
, vol.269
, pp. 347-351
-
-
Nicolas-Frances, V.1
Dasari, V.K.2
Abruzzi, E.3
Osumi, T.4
Latruffe, N.5
-
150
-
-
0028953133
-
Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription
-
Aldridge TC, Tungwood JD, Green S: Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription. Biochem. J. 306, 473-479 (1995).
-
(1995)
Biochem. J
, vol.306
, pp. 473-479
-
-
Aldridge, T.C.1
Tungwood, J.D.2
Green, S.3
-
151
-
-
0030766476
-
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice
-
Peters JM, Hennuyer N, Staels B et al.: Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice. J. Biol. Chem. 272, 27307-27312 (1997).
-
(1997)
J. Biol. Chem
, vol.272
, pp. 27307-27312
-
-
Peters, J.M.1
Hennuyer, N.2
Staels, B.3
-
152
-
-
0032489437
-
Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα,)
-
Aoyama T, Peters JM, Iritani N et al.: Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα,). J. Biol. Chem. 273, 5678-5684 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 5678-5684
-
-
Aoyama, T.1
Peters, J.M.2
Iritani, N.3
-
153
-
-
0032491614
-
Peroxisome proliferator-activated receptor α-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis
-
Costet P, Legerdre C, More J, Edger A, Galtier P, Pineau T: Peroxisome proliferator-activated receptor α-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis. J. Biol. Chem. 273, 29577-29585 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 29577-29585
-
-
Costet, P.1
Legerdre, C.2
More, J.3
Edger, A.4
Galtier, P.5
Pineau, T.6
-
154
-
-
0026541591
-
The mouse peroxisome, proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene
-
Tugwood JD, Issemann I, Anderson RG, Bundell KR, McPheat WL, Green S: The mouse peroxisome, proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene. EMBO J. 11, 433-439 (1992).
-
(1992)
EMBO J
, vol.11
, pp. 433-439
-
-
Tugwood, J.D.1
Issemann, I.2
Anderson, R.G.3
Bundell, K.R.4
McPheat, W.L.5
Green, S.6
-
155
-
-
0032699670
-
Peroxisome proliferator-activated receptor α mediates the adaptive response to fasting
-
Kersten S, Seydoux J, Petes JM, Gonzalez FJ, Desvergne B, Wahli W: Peroxisome proliferator-activated receptor α mediates the adaptive response to fasting. J. Clin. Invest. 103, 1489-1498 (1999).
-
(1999)
J. Clin. Invest
, vol.103
, pp. 1489-1498
-
-
Kersten, S.1
Seydoux, J.2
Petes, J.M.3
Gonzalez, F.J.4
Desvergne, B.5
Wahli, W.6
-
156
-
-
0033594980
-
A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders
-
Leone TC, Weinheimer CJ, Kelly DP: A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders. Proc. Natl Acad. Sci. USA 96, 7473-7478 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 7473-7478
-
-
Leone, T.C.1
Weinheimer, C.J.2
Kelly, D.P.3
-
157
-
-
4644231528
-
Nuclear receptor signaling and cardiac energetics
-
Huss JM, Kelly DP: Nuclear receptor signaling and cardiac energetics. Circ. Res. 95, 568-578 (2004).
-
(2004)
Circ. Res
, vol.95
, pp. 568-578
-
-
Huss, J.M.1
Kelly, D.P.2
-
159
-
-
0016228177
-
Effect of dietary fats and fatty acids on the liver lipid accumulation induced by feeding a protein-repletion diet containing fructose to protein-depleted rats
-
Aoyama Y, Yoshida A, Ashida K: Effect of dietary fats and fatty acids on the liver lipid accumulation induced by feeding a protein-repletion diet containing fructose to protein-depleted rats. J. Nutr. 104, 741-746 (1974).
-
(1974)
J. Nutr
, vol.104
, pp. 741-746
-
-
Aoyama, Y.1
Yoshida, A.2
Ashida, K.3
-
160
-
-
29744433021
-
Consuming fructose-sweetened beverages increases body adiposity in mice
-
Jurgens H, Hass W, Castaneda TR et al.: Consuming fructose-sweetened beverages increases body adiposity in mice. Obes. Res. 13, 1146-1156 (2005).
-
(2005)
Obes. Res
, vol.13
, pp. 1146-1156
-
-
Jurgens, H.1
Hass, W.2
Castaneda, T.R.3
-
161
-
-
0036084269
-
Amelioration of high fructose-induced metabolic derangements by activation of PPARα
-
Nagai Y, Nishio Y, Nakamura T, Maegawa H, Kikkawa R, Kashiwagi A: Amelioration of high fructose-induced metabolic derangements by activation of PPARα. Am. J. Physiol. Endocrinol. Metab. 282, E1180-E1190 (2002).
-
(2002)
Am. J. Physiol. Endocrinol. Metab
, vol.282
-
-
Nagai, Y.1
Nishio, Y.2
Nakamura, T.3
Maegawa, H.4
Kikkawa, R.5
Kashiwagi, A.6
-
162
-
-
0842291584
-
High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation
-
Kelley GL, Allan G, Azhar S: High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation. Endocrinology 145, 548-555 (2004).
-
(2004)
Endocrinology
, vol.145
, pp. 548-555
-
-
Kelley, G.L.1
Allan, G.2
Azhar, S.3
-
163
-
-
22144481333
-
Fructose selectively modulates c-jun N-terminal kinase activity and insulin signaling in rat primary hepatocytes
-
Wei Y, Wang D, Pagliassotti MJ: Fructose selectively modulates c-jun N-terminal kinase activity and insulin signaling in rat primary hepatocytes. J. Nutr. 135, 1642-1646 (2005).
-
(2005)
J. Nutr
, vol.135
, pp. 1642-1646
-
-
Wei, Y.1
Wang, D.2
Pagliassotti, M.J.3
-
164
-
-
15744394674
-
Fructose, insulin resistance, and metabolic dyslipidemia
-
Basciano H, Federico L, Adeli K: Fructose, insulin resistance, and metabolic dyslipidemia. Nutr. Metab. (Lond.). 2, 5 (2005).
-
(2005)
Nutr. Metab. (Lond.)
, vol.2
, pp. 5
-
-
Basciano, H.1
Federico, L.2
Adeli, K.3
-
165
-
-
0034467428
-
PPAR signaling in the control of cardiac energy metabolism
-
Berger PM, Kelly DP: PPAR signaling in the control of cardiac energy metabolism. Trends Cardiovasc. Med. 10, 238-245 (2000).
-
(2000)
Trends Cardiovasc. Med
, vol.10
, pp. 238-245
-
-
Berger, P.M.1
Kelly, D.P.2
-
166
-
-
0032771096
-
The role of the peroxisome proliferator-activated receptor α (PPARα) in the control of cardiac lipid metabolism
-
Djouadi F, Brandt J, Weinheimer CJ, Leone TC, Gonzalez FJ, Kelley DP: The role of the peroxisome proliferator-activated receptor α (PPARα) in the control of cardiac lipid metabolism. Prostaglandins Leukot. Essent. Fatty Acids 60, 339-343 (1999).
-
(1999)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.60
, pp. 339-343
-
-
Djouadi, F.1
Brandt, J.2
Weinheimer, C.J.3
Leone, T.C.4
Gonzalez, F.J.5
Kelley, D.P.6
-
167
-
-
0034698051
-
Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor α associated with age-dependent cardiac toxicity
-
Watanabe K, Fujii H, Takahashi T et al.: Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor α associated with age-dependent cardiac toxicity. J. Biol. Chem. 275, 22293-22299 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 22293-22299
-
-
Watanabe, K.1
Fujii, H.2
Takahashi, T.3
-
168
-
-
0037040203
-
A role for PPARa° in the control of cardiac malonyl-CoA levels: Reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARα are associated with higher concentrations of malonyl-CoA and reduced expression of malonyl-CoA decarboxylase
-
Campbell FM, Kozak R, Wagner A et al.: A role for PPARa° in the control of cardiac malonyl-CoA levels: Reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARα are associated with higher concentrations of malonyl-CoA and reduced expression of malonyl-CoA decarboxylase. J. Biol. Chem. 277, 4098-4103 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 4098-4103
-
-
Campbell, F.M.1
Kozak, R.2
Wagner, A.3
-
169
-
-
0033594980
-
A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders
-
Leone TC, Weinheimer CJ, Kelly DP: A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders. Proc. Natl Acad. Sci. USA 96, 7473-7478 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 7473-7478
-
-
Leone, T.C.1
Weinheimer, C.J.2
Kelly, D.P.3
-
170
-
-
0036143320
-
The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus
-
Finck BN, Lehman JJ, Leone TC et al.: The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus. J. Clin. Invest. 109, 121-130 (2002).
-
(2002)
J. Clin. Invest
, vol.109
, pp. 121-130
-
-
Finck, B.N.1
Lehman, J.J.2
Leone, T.C.3
-
171
-
-
0037417725
-
A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
-
Finck BN, Han X, Courtois M et al.: A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content. Proc. Natl Acad. Sci. USA 100, 1226-1231 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 1226-1231
-
-
Finck, B.N.1
Han, X.2
Courtois, M.3
-
172
-
-
24144490615
-
Cardiac-specific overexpression of peroxisome proliferator-activated receptor-α causes insulin resistance in heart and liver
-
Park S-Y, Cho Y-R, Fink BN et al.: Cardiac-specific overexpression of peroxisome proliferator-activated receptor-α causes insulin resistance in heart and liver. Diabetes 54, 2514-2524 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 2514-2524
-
-
Park, S.-Y.1
Cho, Y.-R.2
Fink, B.N.3
-
173
-
-
0033933236
-
Deactivation of peroxisome proliferator-activated receptor-α during cardiac hypertrophic growth
-
Barger PM, Brandt JM, Leone TC, Weinheimer CJ, Kelly DP: Deactivation of peroxisome proliferator-activated receptor-α during cardiac hypertrophic growth. J. Clin. Invest. 105, 1723-1730 (2000).
-
(2000)
J. Clin. Invest
, vol.105
, pp. 1723-1730
-
-
Barger, P.M.1
Brandt, J.M.2
Leone, T.C.3
Weinheimer, C.J.4
Kelly, D.P.5
-
174
-
-
0035976932
-
Reactivation of peroxisome proliferator-activated receptor α is associated with contractile dysfunction in hypertrophied rat heart
-
Young ME, Laws FA, Goodwin GW, Taegtmeyer H: Reactivation of peroxisome proliferator-activated receptor α is associated with contractile dysfunction in hypertrophied rat heart. J. Biol. Chem. 276, 44390-44395 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 44390-44395
-
-
Young, M.E.1
Laws, F.A.2
Goodwin, G.W.3
Taegtmeyer, H.4
-
175
-
-
34249279594
-
Hypoxia inhibits the PPARα/RXR gene regulatory pathway in cardiac myocytes
-
Huss JM, Levy FH, Kelly DP: Hypoxia inhibits the PPARα/RXR gene regulatory pathway in cardiac myocytes. J. Biol. Chem. 276, 44390-44395 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 44390-44395
-
-
Huss, J.M.1
Levy, F.H.2
Kelly, D.P.3
-
176
-
-
0035860177
-
Hypoxia in vivo decreases peroxisome proliferator-activated receptor α-regulated gene expression in rat heart
-
Razeghi P, Young ME, Abbasi S, Taegtmeyer H: Hypoxia in vivo decreases peroxisome proliferator-activated receptor α-regulated gene expression in rat heart. Biochem. Biophys. Res. Commun. 287, 5-10 (2001).
-
(2001)
Biochem. Biophys. Res. Commun
, vol.287
, pp. 5-10
-
-
Razeghi, P.1
Young, M.E.2
Abbasi, S.3
Taegtmeyer, H.4
-
177
-
-
0037459356
-
PPATs of the heart: There is a crowd
-
Kelley DP: PPATs of the heart: there is a crowd. Circ. Res. 92, 482-484 (2003).
-
(2003)
Circ. Res
, vol.92
, pp. 482-484
-
-
Kelley, D.P.1
-
178
-
-
0032479423
-
Expression of putative fatty acid transport genes are regulated by peroxisome proliferator-activated receptor α and γ activators in a tissue- and inducer-specific manner
-
Motojima K, Passilly P, Peters JM, Gonzalez FJ, Latruffe N: Expression of putative fatty acid transport genes are regulated by peroxisome proliferator-activated receptor α and γ activators in a tissue- and inducer-specific manner. J. Biol. Chem. 273, 16710-16714 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 16710-16714
-
-
Motojima, K.1
Passilly, P.2
Peters, J.M.3
Gonzalez, F.J.4
Latruffe, N.5
-
179
-
-
0036349314
-
Adenoviral overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice
-
van der Vliet HN, Schaap FG, Levels JH et al: Adenoviral overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice. Biochem. Biophys. Res. Commun. 295, 1156-1159 (2002).
-
(2002)
Biochem. Biophys. Res. Commun
, vol.295
, pp. 1156-1159
-
-
van der Vliet, H.N.1
Schaap, F.G.2
Levels, J.H.3
-
180
-
-
23244459004
-
Administration of PPARα agonist increases serum apolipoprotein A-V levels and the apolipoprotein A-V/apolipoprotein C-III ratio
-
Schultze A, Alborn WE, Mewton RK, Konrad RJ: Administration of PPARα agonist increases serum apolipoprotein A-V levels and the apolipoprotein A-V/apolipoprotein C-III ratio. J. Lipid Res. 46, 1591-1595 (2005).
-
(2005)
J. Lipid Res
, vol.46
, pp. 1591-1595
-
-
Schultze, A.1
Alborn, W.E.2
Mewton, R.K.3
Konrad, R.J.4
-
181
-
-
28144436041
-
Hepatocyte nuclear factar-4α regulates the human apolipoprotem AV gene: Identification of a novel response element and involvement in the control by peroxisome proliferator-activated receptor-γ coactivator-1a, AMP-activated protein kinase, and mitogen-activated protein kinase pathway
-
Prieur X, Schapp FG, Coste H, Rodríguez JC: Hepatocyte nuclear factar-4α regulates the human apolipoprotem AV gene: Identification of a novel response element and involvement in the control by peroxisome proliferator-activated receptor-γ coactivator-1a, AMP-activated protein kinase, and mitogen-activated protein kinase pathway. Mol. Endocrinol. 19, 3107-3125 (2005).
-
(2005)
Mol. Endocrinol
, vol.19
, pp. 3107-3125
-
-
Prieur, X.1
Schapp, F.G.2
Coste, H.3
Rodríguez, J.C.4
-
182
-
-
23044515047
-
Thyroid hormone regulates the hypotriglyceridemic gene APOA5
-
Prieur X, Huby T, Coste H, Schaap FG, Chapman MJ, Rodríguez JC: Thyroid hormone regulates the hypotriglyceridemic gene APOA5. J. Biol. Chem. 260, 27533-27543 (2005).
-
(2005)
J. Biol. Chem
, vol.260
, pp. 27533-27543
-
-
Prieur, X.1
Huby, T.2
Coste, H.3
Schaap, F.G.4
Chapman, M.J.5
Rodríguez, J.C.6
-
183
-
-
0032102146
-
A fatty acid-dependent step is critically important for both glucose- and non-glucose-stimulated Insulin secretion
-
Dobbins RL, Chester MW, Stevenson BE, Daniels MB, Stein DT, McGarry JD: A fatty acid-dependent step is critically important for both glucose- and non-glucose-stimulated Insulin secretion. J. Clin. Invest. 101, 2370-2376 (1998).
-
(1998)
J. Clin. Invest
, vol.101
, pp. 2370-2376
-
-
Dobbins, R.L.1
Chester, M.W.2
Stevenson, B.E.3
Daniels, M.B.4
Stein, D.T.5
McGarry, J.D.6
-
184
-
-
0036311080
-
β-cell mitochondria and insulin secretion: Messenger role of nucleotides and metabolites
-
Wollheim CB, Maechler P: β-cell mitochondria and insulin secretion: messenger role of nucleotides and metabolites. Diabetes 51(Suppl. 1), S37-S42 (2002).
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 1
-
-
Wollheim, C.B.1
Maechler, P.2
-
185
-
-
0142093526
-
Fatty acid metabolism and insulin secretion in pancreatic β cells
-
Yaney GC, Corkey BE: Fatty acid metabolism and insulin secretion in pancreatic β cells. Diabetologia 46, 1297-1312 (2003).
-
(2003)
Diabetologia
, vol.46
, pp. 1297-1312
-
-
Yaney, G.C.1
Corkey, B.E.2
-
186
-
-
0842285629
-
Potential role of peroxisome proliferator-activated receptor-α in the modulation of glucose-stimulated insulin secretion
-
Sugden MC, Holmes MJ: Potential role of peroxisome proliferator-activated receptor-α in the modulation of glucose-stimulated insulin secretion. Diabetes 53 (Suppl. 1), S71-S81 (2004).
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Sugden, M.C.1
Holmes, M.J.2
-
187
-
-
0032555148
-
Role of peroxisome proliferator-activated receptor α in disease of pancreatic β-cells
-
Zhou Y-T, Shimabukuro M, Wang M-Y et al.: Role of peroxisome proliferator-activated receptor α in disease of pancreatic β-cells. Proc. Natl Acad. Sci. USA 95, 8898-8903 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 8898-8903
-
-
Zhou, Y.-T.1
Shimabukuro, M.2
Wang, M.-Y.3
-
188
-
-
0034680797
-
Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-1 gene in the pancreatic β-cell
-
Roduit R, Morin J, Massé F et al.: Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-1 gene in the pancreatic β-cell. J. Biol. Chem. 275, 35799-35806 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 35799-35806
-
-
Roduit, R.1
Morin, J.2
Massé, F.3
-
189
-
-
19944367869
-
Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor α transcription up-regulation of fatty acid oxidation
-
Gremlich S, Nolan C, Roduit R et al.: Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor α transcription up-regulation of fatty acid oxidation. Endocrinology 146, 375-382 (2005).
-
(2005)
Endocrinology
, vol.146
, pp. 375-382
-
-
Gremlich, S.1
Nolan, C.2
Roduit, R.3
-
190
-
-
23044478417
-
Peroxisome proliferator-activated receptor α (PPARα) potentiates, whereas PPARγ attenuates, glucose-stimulated insulin secretion in pancreatic β-cells
-
Ravnskjaer K, Boergesen M, Rubi B et al.: Peroxisome proliferator-activated receptor α (PPARα) potentiates, whereas PPARγ attenuates, glucose-stimulated insulin secretion in pancreatic β-cells. Endocrinology 146, 3266-3276 (2005).
-
(2005)
Endocrinology
, vol.146
, pp. 3266-3276
-
-
Ravnskjaer, K.1
Boergesen, M.2
Rubi, B.3
-
191
-
-
0034595980
-
Peroxisome proliferator-activated receptor α activators improve insulin sensitivity and reduce adiposity
-
Guerre-Millo M, Gervois P, Raspe E et al.: Peroxisome proliferator-activated receptor α activators improve insulin sensitivity and reduce adiposity. J. Biol. Chem. 275, 16638-16642 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 16638-16642
-
-
Guerre-Millo, M.1
Gervois, P.2
Raspe, E.3
-
192
-
-
0036606670
-
Peroxiosme-proliferator-activated receptor-α (PPARα) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin
-
Sugden MC, Bulmer K, Gibbons GF, Knight BL, Holness MJ: Peroxiosme-proliferator-activated receptor-α (PPARα) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin. Biochem. J. 364, 361-368 (2002).
-
(2002)
Biochem. J
, vol.364
, pp. 361-368
-
-
Sugden, M.C.1
Bulmer, K.2
Gibbons, G.F.3
Knight, B.L.4
Holness, M.J.5
-
193
-
-
0035141142
-
Peroxisome proliferator-activated receptor (PPAR)α activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: Comparison with PPAR γ activation
-
Ye J-M, Doyle PJ, Iglesias MA, Watson DG, Cooney GJ, Kraegen EW: Peroxisome proliferator-activated receptor (PPAR)α activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR γ activation. Diabetes 50, 411-417 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 411-417
-
-
Ye, J.-M.1
Doyle, P.J.2
Iglesias, M.A.3
Watson, D.G.4
Cooney, G.J.5
Kraegen, E.W.6
-
194
-
-
0037025390
-
WY14,643, a peroxisome proliferator-activated receptor α (PPARα) agonist, improves hepatic and muscle steatosis and reverses insulin resistance in lipoatropic A-ZIP/F-1 mice
-
Chou CJ, Haluzik M, Gregory C et al.: WY14,643, a peroxisome proliferator-activated receptor α (PPARα) agonist, improves hepatic and muscle steatosis and reverses insulin resistance in lipoatropic A-ZIP/F-1 mice. J. Biol. Chem. 277, 24484-24489 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 24484-24489
-
-
Chou, C.J.1
Haluzik, M.2
Gregory, C.3
-
195
-
-
0042822095
-
Peroxisome proliferator-activated receptor (PPAR)-α activation prevents diabetes in OLETF rats: Comparison with PPAR-γ activation
-
Koh EH, Kim MS, Park JY et al.: Peroxisome proliferator-activated receptor (PPAR)-α activation prevents diabetes in OLETF rats: comparison with PPAR-γ activation. Diabetes 52, 2331-2337 (2003).
-
(2003)
Diabetes
, vol.52
, pp. 2331-2337
-
-
Koh, E.H.1
Kim, M.S.2
Park, J.Y.3
-
196
-
-
16644377741
-
Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome
-
Guan Y: Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome. J. Am. Soc. Nephrol. 15, 2801-2815 (2004).
-
(2004)
J. Am. Soc. Nephrol
, vol.15
, pp. 2801-2815
-
-
Guan, Y.1
-
197
-
-
85047693466
-
Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ
-
Li AC, Binder C, Gutierrez A et al.: Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ. J. Clin. Invest. 114, 1564-1576 (2004).
-
(2004)
J. Clin. Invest
, vol.114
, pp. 1564-1576
-
-
Li, A.C.1
Binder, C.2
Gutierrez, A.3
-
198
-
-
33646192257
-
Peroxisome proliferator-activated receptor-α selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice
-
Srivastava RA, Jahagirdar R, Azhar S, Sharma S, Bisgaier CL: Peroxisome proliferator-activated receptor-α selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice. Mol. Cell. Biochem. 285, 35-50 (2006).
-
(2006)
Mol. Cell. Biochem
, vol.285
, pp. 35-50
-
-
Srivastava, R.A.1
Jahagirdar, R.2
Azhar, S.3
Sharma, S.4
Bisgaier, C.L.5
-
199
-
-
0037225451
-
Peroxisome proliferator-activated receptor-α activation during pregnancy attenuates glucose-stimulated insulin hypersecretion in vivo by increasing insulin sensitivity, without impairing pregnancy-induced increases in β-cell glucose sensing and responsiveness
-
Sugden MC, Greenwood GK, Smith ND, Holness MJ: Peroxisome proliferator-activated receptor-α activation during pregnancy attenuates glucose-stimulated insulin hypersecretion in vivo by increasing insulin sensitivity, without impairing pregnancy-induced increases in β-cell glucose sensing and responsiveness. Endocrinology 144, 146-153 (2003).
-
(2003)
Endocrinology
, vol.144
, pp. 146-153
-
-
Sugden, M.C.1
Greenwood, G.K.2
Smith, N.D.3
Holness, M.J.4
-
200
-
-
0141611975
-
The potential role of peroxisome proliferator-activated receptors on inflammation in Type 2 diabetes mellitus and atherosclerosis
-
Plutzky J: The potential role of peroxisome proliferator-activated receptors on inflammation in Type 2 diabetes mellitus and atherosclerosis. Am. J. Cardiol. 92, 34-41 (2003).
-
(2003)
Am. J. Cardiol
, vol.92
, pp. 34-41
-
-
Plutzky, J.1
-
201
-
-
24144461233
-
Inflammation, atherosclerosis, and aspects of insulin action
-
Bloomgarden ZT: Inflammation, atherosclerosis, and aspects of insulin action. Diabetes Care 28, 2312-2319 (2005).
-
(2005)
Diabetes Care
, vol.28
, pp. 2312-2319
-
-
Bloomgarden, Z.T.1
-
202
-
-
0034648768
-
Atherosclerosis
-
Lusis AJ: Atherosclerosis. Nature 407, 233-241 (2000).
-
(2000)
Nature
, vol.407
, pp. 233-241
-
-
Lusis, A.J.1
-
203
-
-
17644412023
-
Inflammation, atherosclerosis, and coronary artery disease
-
Hansson GK: Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 352, 1685-1695 (2005).
-
(2005)
N. Engl. J. Med
, vol.352
, pp. 1685-1695
-
-
Hansson, G.K.1
-
204
-
-
32944473282
-
Nuclear reTeptors in lipid metabolism: Targeting the heart of dyslipidemia
-
Beaven SW, Tontonoz P: Nuclear reTeptors in lipid metabolism: targeting the heart of dyslipidemia. Annu. Rev. Med. 57, 313-329 (2006).
-
(2006)
Annu. Rev. Med
, vol.57
, pp. 313-329
-
-
Beaven, S.W.1
Tontonoz, P.2
-
205
-
-
33644828263
-
Obesity, peroxisome proliferator activated receptor, and atherosclerosis in Type 2 diabetes
-
Blaschke F, Takata Y, Caglayan E et al.: Obesity, peroxisome proliferator activated receptor, and atherosclerosis in Type 2 diabetes. Arterioscler. Thromb. Vasc. Biol. 26, 28-40 (2005).
-
(2005)
Arterioscler. Thromb. Vasc. Biol
, vol.26
, pp. 28-40
-
-
Blaschke, F.1
Takata, Y.2
Caglayan, E.3
-
206
-
-
0037071843
-
Subendothelial retention of atherogenic lipoproteins in early atherosclerosis
-
Skalen K, Gustafsson M, Rydberg EK et al.: Subendothelial retention of atherogenic lipoproteins in early atherosclerosis. Nature 417, 750-754 (2002).
-
(2002)
Nature
, vol.417
, pp. 750-754
-
-
Skalen, K.1
Gustafsson, M.2
Rydberg, E.K.3
-
207
-
-
0032546485
-
Expression of peroxisome proliferator-activated receptor α (PPARα) in primary cultures of human vascular endothelial cells
-
Inoue I, Shino K, Awata T, Katayama S: Expression of peroxisome proliferator-activated receptor α (PPARα) in primary cultures of human vascular endothelial cells. Biochem. Biophys. Res. Commun. 246, 370-374 (1998).
-
(1998)
Biochem. Biophys. Res. Commun
, vol.246
, pp. 370-374
-
-
Inoue, I.1
Shino, K.2
Awata, T.3
Katayama, S.4
-
208
-
-
0032565868
-
Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators
-
Staels B, Koening W, Habib A, Merval R, Lebret M, Torra IP: Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators. Nature 393, 790-793 (1998).
-
(1998)
Nature
, vol.393
, pp. 790-793
-
-
Staels, B.1
Koening, W.2
Habib, A.3
Merval, R.4
Lebret, M.5
Torra, I.P.6
-
209
-
-
0032475922
-
Activation of proliferator-activated receptor α and γ induces apoptosis of human monocyte-derived macrophages
-
Chinetti G, Griglio S, Antonucci M, Torra IP, Delerive P, Majd Z: Activation of proliferator-activated receptor α and γ induces apoptosis of human monocyte-derived macrophages. J. Biol. Chem. 273, 25573-25580 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 25573-25580
-
-
Chinetti, G.1
Griglio, S.2
Antonucci, M.3
Torra, I.P.4
Delerive, P.5
Majd, Z.6
-
210
-
-
0034705071
-
CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors
-
Chinetti G, Gbaguidi FG, Griglio S, Mallat Z, Antonucci M, Poulain P: CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors. Circulation 101, 2411-2417 (2000).
-
(2000)
Circulation
, vol.101
, pp. 2411-2417
-
-
Chinetti, G.1
Gbaguidi, F.G.2
Griglio, S.3
Mallat, Z.4
Antonucci, M.5
Poulain, P.6
-
211
-
-
0032827327
-
9-Cis retinoic acid induces monocyte chemoattractant protein-1 secretion in human monocytic THP-1 cells
-
Zhu L, Bisgaier CL, Aviram M, Newton RS: 9-Cis retinoic acid induces monocyte chemoattractant protein-1 secretion in human monocytic THP-1 cells. Arterioscler. Thromb. Vasc. Biol. 19, 2105-2111 (1999).
-
(1999)
Arterioscler. Thromb. Vasc. Biol
, vol.19
, pp. 2105-2111
-
-
Zhu, L.1
Bisgaier, C.L.2
Aviram, M.3
Newton, R.S.4
-
212
-
-
0033520304
-
Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway
-
Delerive P, Martin-Nizard F, Chinetti G et al.: Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway. Circ. Res. 85, 394-402 (1999).
-
(1999)
Circ. Res
, vol.85
, pp. 394-402
-
-
Delerive, P.1
Martin-Nizard, F.2
Chinetti, G.3
-
213
-
-
0032847680
-
Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction
-
Jackson SM, Parhami F, Xi XP et al.: Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction. Arterioscler. Thromb. Vasc. Biol. 19, 2094-2104 (1999).
-
(1999)
Arterioscler. Thromb. Vasc. Biol
, vol.19
, pp. 2094-2104
-
-
Jackson, S.M.1
Parhami, F.2
Xi, X.P.3
-
214
-
-
0033594810
-
PPARα activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells
-
Marx N, Sukhova GK, Collins T, Libby P, Plutzky J: PPARα activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation 99, 3125-3131 (1999).
-
(1999)
Circulation
, vol.99
, pp. 3125-3131
-
-
Marx, N.1
Sukhova, G.K.2
Collins, T.3
Libby, P.4
Plutzky, J.5
-
215
-
-
0034614270
-
Activation of PPARα or γ reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells
-
Shu H, Wong B, Zhou G et al.: Activation of PPARα or γ reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells. Biochem. Biophys. Res. Commun. 267, 345-349 (2000).
-
(2000)
Biochem. Biophys. Res. Commun
, vol.267
, pp. 345-349
-
-
Shu, H.1
Wong, B.2
Zhou, G.3
-
216
-
-
0035138625
-
PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
-
Chinetti G, Lestavel S, Bocher V et al.: PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat. Med. 7, 53-58 (2001).
-
(2001)
Nat. Med
, vol.7
, pp. 53-58
-
-
Chinetti, G.1
Lestavel, S.2
Bocher, V.3
-
217
-
-
0035895313
-
PPARα agonists inhibit tissue factor expression in human monocytes and macrophages
-
Neve BP, Corseaux D, Chinetti G et al.: PPARα agonists inhibit tissue factor expression in human monocytes and macrophages. Circulation 103, 207-212 (2001).
-
(2001)
Circulation
, vol.103
, pp. 207-212
-
-
Neve, B.P.1
Corseaux, D.2
Chinetti, G.3
-
218
-
-
0035895326
-
PPARα activators inhibit tissue factor expression and activity in human monocytes
-
Marx N, Mackman N, Schonbeck U et al.: PPARα activators inhibit tissue factor expression and activity in human monocytes. Circulation 103, 213-219 (2001).
-
(2001)
Circulation
, vol.103
, pp. 213-219
-
-
Marx, N.1
Mackman, N.2
Schonbeck, U.3
-
219
-
-
0036255486
-
DNA binding-independent induction of IκBα gene transcription by PPARα
-
Delerive P, De Bosscher K, Vanden-Berghe W, Fruchart JC, Haegeman G, Staels B: DNA binding-independent induction of IκBα gene transcription by PPARα. Mol. Endocrinol. 16, 1029-1039 (2002).
-
(2002)
Mol. Endocrinol
, vol.16
, pp. 1029-1039
-
-
Delerive, P.1
De Bosscher, K.2
Vanden-Berghe, W.3
Fruchart, J.C.4
Haegeman, G.5
Staels, B.6
-
220
-
-
0033527569
-
Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1
-
Delerive P, De Bosscher K, Besnard S, Vanden-Berghe W, Peters JM, Gonzalez FJ: Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1. J. Biol. Chem. 274, 32048-32054 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 32048-32054
-
-
Delerive, P.1
De Bosscher, K.2
Besnard, S.3
Vanden-Berghe, W.4
Peters, J.M.5
Gonzalez, F.J.6
-
221
-
-
0032484123
-
Peroxisome proliferator-activated receptor α activation modulates cellular redox status, represses nuclear factor-κB signaling, and reduces inflammatory cytokine production in aging
-
Poynter ME, Daynes RA: Peroxisome proliferator-activated receptor α activation modulates cellular redox status, represses nuclear factor-κB signaling, and reduces inflammatory cytokine production in aging. J. Biol. Chem. 273, 32833-32841 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 32833-32841
-
-
Poynter, M.E.1
Daynes, R.A.2
-
222
-
-
0031813989
-
Effects of fenofibrate on plasma cytokine concentrations in patients with atherosclerosis and hyperlipoproteinemia IIB
-
Madej A, Okopien B, Kowalski J, Zielinski M, Wysocki J, Szygula B: Effects of fenofibrate on plasma cytokine concentrations in patients with atherosclerosis and hyperlipoproteinemia IIB. Int. J. Clin. Pharmacol. Ther. 36, 345-349 (1998).
-
(1998)
Int. J. Clin. Pharmacol. Ther
, vol.36
, pp. 345-349
-
-
Madej, A.1
Okopien, B.2
Kowalski, J.3
Zielinski, M.4
Wysocki, J.5
Szygula, B.6
-
223
-
-
11144355198
-
Peroxisome proliferator-activated receptor a agonists increase nitric oxide synthase expression in vascular endothelial cells
-
Goya K, Sumitani S, Xu X, Kitamura T, Yamamoto H, Kurebayashi S: Peroxisome proliferator-activated receptor a agonists increase nitric oxide synthase expression in vascular endothelial cells. Arterioscler. Thromb. Vasc. Biol. 24, 658-663 (2004).
-
(2004)
Arterioscler. Thromb. Vasc. Biol
, vol.24
, pp. 658-663
-
-
Goya, K.1
Sumitani, S.2
Xu, X.3
Kitamura, T.4
Yamamoto, H.5
Kurebayashi, S.6
-
224
-
-
0029009534
-
Nitric oxide and vascular tone
-
Loscalzo J: Nitric oxide and vascular tone. N. Engl. J. Med. 333, 251-253 (1995).
-
(1995)
N. Engl. J. Med
, vol.333
, pp. 251-253
-
-
Loscalzo, J.1
-
225
-
-
0029159779
-
Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
-
De Caterina R, Libby P, Peng HB et al.: Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J. Clin. Invest. 96, 60-68 (1995).
-
(1995)
J. Clin. Invest
, vol.96
, pp. 60-68
-
-
De Caterina, R.1
Libby, P.2
Peng, H.B.3
-
226
-
-
10044223533
-
PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis
-
Li AC, Glass CG: PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis. J. Lipid Res. 45, 2161-2173 (2004).
-
(2004)
J. Lipid Res
, vol.45
, pp. 2161-2173
-
-
Li, A.C.1
Glass, C.G.2
-
227
-
-
34249310015
-
The PPARα-leukotriene B4 pathway to inflammation
-
Devchand PR, Keller H, Peters JM, Vasquez M, Gonzalez FJ, Wahli W: The PPARα-leukotriene B4 pathway to inflammation. Nature 384, 23-24 (1996).
-
(1996)
Nature
, vol.384
, pp. 23-24
-
-
Devchand, P.R.1
Keller, H.2
Peters, J.M.3
Vasquez, M.4
Gonzalez, F.J.5
Wahli, W.6
-
228
-
-
33745309774
-
The role of the peroxisome proliferators-activated receptor-α (PPAR-α) in the regulation of acute inflammation
-
Cuzzocrea S, Mazzon E, Di Paola R et al.: The role of the peroxisome proliferators-activated receptor-α (PPAR-α) in the regulation of acute inflammation. J. Leukoc. Biol. 79, 999-1010 (2006).
-
(2006)
J. Leukoc. Biol
, vol.79
, pp. 999-1010
-
-
Cuzzocrea, S.1
Mazzon, E.2
Di Paola, R.3
-
229
-
-
0034744590
-
PPARα deficiency reduces insulin resistance and atherosclerosis in apoE-null mice
-
Tordjman K, Bernal-Mizrachi C, Zemany L et al.: PPARα deficiency reduces insulin resistance and atherosclerosis in apoE-null mice. J. Clin. Invest. 107, 1025-1034 (2001).
-
(2001)
J. Clin. Invest
, vol.107
, pp. 1025-1034
-
-
Tordjman, K.1
Bernal-Mizrachi, C.2
Zemany, L.3
-
230
-
-
0042568979
-
The peroxisome proliferator-activated receptor α against ciprofibrate severely aggravates hypercholesterolaemia and accelerates the development of atherosclerosis in mice lacking apolipoprotein E
-
Fu T, Kashireddy P, Borensztajn J: The peroxisome proliferator-activated receptor α against ciprofibrate severely aggravates hypercholesterolaemia and accelerates the development of atherosclerosis in mice lacking apolipoprotein E. Biochem. J. 373, 941-947 (2003).
-
(2003)
Biochem. J
, vol.373
, pp. 941-947
-
-
Fu, T.1
Kashireddy, P.2
Borensztajn, J.3
-
231
-
-
0035957006
-
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor
-
Claudel T, Leibowitz MD, Fievet C et al.: Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor. Proc. Natl Acad. Sci. USA 98, 2610-2615 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 2610-2615
-
-
Claudel, T.1
Leibowitz, M.D.2
Fievet, C.3
-
232
-
-
2242436246
-
Reduction of atherosclerosis by the peroxisome proliferator-activated receptor α agonist fenofibrate in mice
-
Duez H, Chao YS, Hernandez G et al.: Reduction of atherosclerosis by the peroxisome proliferator-activated receptor α agonist fenofibrate in mice. J. Biol. Chem. 277, 48051-48057 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 48051-48057
-
-
Duez, H.1
Chao, Y.S.2
Hernandez, G.3
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