Peroxisome proliferator-activated receptor-α activation during pregnancy attenuates glucose-stimulated insulin hypersecretion in vivo by increasing insulin sensitivity, without impairing pregnancy-induced increases in β-cell glucose sensing and responsiveness

Endocrinology

Volumn 144, Issue 1, 2003, Pages 146-153

  Sugden, Mary C ^a   Greenwood, Gemma K ^a   Smith, Nicholas D ^a   Holness, Mark J ^a,b  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HYPOINSULINEMIA; IN VIVO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN RESPONSE; INSULIN SENSITIVITY; NONHUMAN; PANCREAS ISLET CELL; PREGNANCY; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

ANIMALS; BLOOD GLUCOSE; EATING; FATTY ACIDS, NONESTERIFIED; FEMALE; FOOD; GLUCOSE; INSULIN; INSULIN RESISTANCE; ISLETS OF LANGERHANS; PREGNANCY; PREGNANCY, ANIMAL; PYRIMIDINES; RATS; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS; TRIGLYCERIDES; WEIGHT GAIN;

EID: 0037225451     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-220811     Document Type: Article

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