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Volumn 52, Issue 9, 2003, Pages 2331-2337

Peroxisome proliferator-activated receptor (PPAR)-α activation prevents diabetes in OLETF rats: Comparison with PPAR-γ activation

Author keywords

[No Author keywords available]

Indexed keywords

FENOFIBRATE; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; ROSIGLITAZONE; TRIACYLGLYCEROL;

EID: 0042822095     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.9.2331     Document Type: Article
Times cited : (137)

References (36)
  • 1
    • 0035345532 scopus 로고    scopus 로고
    • Skeletal muscle triglyceride: An aspect of regional adiposity and insulin resistance
    • Kelley DE, Goodpaster BH: Skeletal muscle triglyceride: an aspect of regional adiposity and insulin resistance. Diabetes Care 24:933-941, 2001
    • (2001) Diabetes Care , vol.24 , pp. 933-941
    • Kelley, D.E.1    Goodpaster, B.H.2
  • 2
    • 0035125917 scopus 로고    scopus 로고
    • Lipotoxicity of β-cells in obesity and in other causes of fatty acid spillover
    • Unger RH, Zhou YT: Lipotoxicity of β-cells in obesity and in other causes of fatty acid spillover. Diabetes 50:S118-S121, 2001
    • (2001) Diabetes , vol.50
    • Unger, R.H.1    Zhou, Y.T.2
  • 3
    • 0033615353 scopus 로고    scopus 로고
    • PPAR γ: An essential regulator of adipogenesis and modulator of fat cell function
    • Lowell BB: PPAR γ: an essential regulator of adipogenesis and modulator of fat cell function. Cell 99:239-242, 1999
    • (1999) Cell , vol.99 , pp. 239-242
    • Lowell, B.B.1
  • 4
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPARgamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPARgamma). J Biol Chem 270:12953-12956, 1995
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 5
    • 0035141142 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR)-α activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: Comparison with PPAR-α activation
    • Ye JM, Doyle PJ, Iglesias MA, Watson DG, Cooney GJ, Kraegen EW: Peroxisome proliferator-activated receptor (PPAR)-α activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-α activation. Diabetes 50:411-417, 2001
    • (2001) Diabetes , vol.50 , pp. 411-417
    • Ye, J.M.1    Doyle, P.J.2    Iglesias, M.A.3    Watson, D.G.4    Cooney, G.J.5    Kraegen, E.W.6
  • 6
    • 0032488968 scopus 로고    scopus 로고
    • Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats
    • Shimabukuro M, Zhou YT, Lee Y, Unger RH: Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats. J Biol Chem 273:3547-3550, 1998
    • (1998) J Biol Chem , vol.273 , pp. 3547-3550
    • Shimabukuro, M.1    Zhou, Y.T.2    Lee, Y.3    Unger, R.H.4
  • 7
    • 0030747895 scopus 로고    scopus 로고
    • Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-α in humans: No alteration in adipose tissue of obese and NIDDM patients
    • Auboeuf D, Rieusset J, Fajas L, Vallier P, Frering V, Riou JP, Staels B, Auwerx J, Laville M, Vidal H: Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-α in humans: no alteration in adipose tissue of obese and NIDDM patients. Diabetes 46:1319-1327, 1997
    • (1997) Diabetes , vol.46 , pp. 1319-1327
    • Auboeuf, D.1    Rieusset, J.2    Fajas, L.3    Vallier, P.4    Frering, V.5    Riou, J.P.6    Staels, B.7    Auwerx, J.8    Laville, M.9    Vidal, H.10
  • 8
    • 0036381966 scopus 로고    scopus 로고
    • Thiazolidinediones: Metabolic actions in vitro
    • Furnsinn C, Waldhausl W: Thiazolidinediones: metabolic actions in vitro. Diabetologia 45:1211-1223, 2002
    • (2002) Diabetologia , vol.45 , pp. 1211-1223
    • Furnsinn, C.1    Waldhausl, W.2
  • 9
    • 0036789137 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
    • Yu JG, Javorschi S, Hevener AL, Kruszynska YT, Norman RA, Sinha M, Olefsky JM: The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 51:2698-2674, 2002
    • (2002) Diabetes , vol.51 , pp. 2698-2674
    • Yu, J.G.1    Javorschi, S.2    Hevener, A.L.3    Kruszynska, Y.T.4    Norman, R.A.5    Sinha, M.6    Olefsky, J.M.7
  • 11
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
    • Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W: Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137:354-366, 1996
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 12
    • 0028033268 scopus 로고
    • The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression
    • Gulick T, Cresci S, Caira T, Moore DD, Kelly DP: The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc Natl Acad Sci U S A 91:11012-11016, 1994
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 11012-11016
    • Gulick, T.1    Cresci, S.2    Caira, T.3    Moore, D.D.4    Kelly, D.P.5
  • 13
  • 16
    • 0030469854 scopus 로고    scopus 로고
    • A method for estimating number and mass of islets transplanted within a membrane device
    • Suzuki K, Bonner-Weir S, Hollister J, Weir GC: A method for estimating number and mass of islets transplanted within a membrane device. Cell Transplant 5:613-625, 1996
    • (1996) Cell Transplant , vol.5 , pp. 613-625
    • Suzuki, K.1    Bonner-Weir, S.2    Hollister, J.3    Weir, G.C.4
  • 17
    • 0025729965 scopus 로고
    • Adipose tissue volume measured by magnetic resonance imaging and computerized tomography in rats
    • Ross R, Leger L, Guardo R, De Guise J, Pike BG: Adipose tissue volume measured by magnetic resonance imaging and computerized tomography in rats. J Appl Physiol 70:2164-2172, 1991
    • (1991) J Appl Physiol , vol.70 , pp. 2164-2172
    • Ross, R.1    Leger, L.2    Guardo, R.3    De Guise, J.4    Pike, B.G.5
  • 19
    • 0028327182 scopus 로고
    • Time courses of changes in hepatic and skeletal muscle insulin action and GLUT4 protein in skeletal muscle after STZ injection
    • Youn JH, Kim JK, Buchanan TA: Time courses of changes in hepatic and skeletal muscle insulin action and GLUT4 protein in skeletal muscle after STZ injection. Diabetes 43:564-571, 1994
    • (1994) Diabetes , vol.43 , pp. 564-571
    • Youn, J.H.1    Kim, J.K.2    Buchanan, T.A.3
  • 20
    • 0022036226 scopus 로고
    • Dose response curve for in vitro insulin sensitivity in individual tissues in rats
    • Kraegen EW, James DE, Jenkins AB, Chisholm DJ: Dose response curve for in vitro insulin sensitivity in individual tissues in rats. Am J Physiol 248:E353-E362, 1985
    • (1985) Am J Physiol , vol.248
    • Kraegen, E.W.1    James, D.E.2    Jenkins, A.B.3    Chisholm, D.J.4
  • 21
    • 0017159024 scopus 로고
    • A rapid method for the determination of glycogen content and radioactivity in small quantities of tissue or isolated hepatocytes
    • Chan TM, Exton JH: A rapid method for the determination of glycogen content and radioactivity in small quantities of tissue or isolated hepatocytes. Anal Biochem 71:96-105, 1976
    • (1976) Anal Biochem , vol.71 , pp. 96-105
    • Chan, T.M.1    Exton, J.H.2
  • 23
    • 0023224147 scopus 로고
    • Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection
    • Gotoh M, Maki T, Satomi S, Porter J, Bonner-Weir S, O'Hara CJ, Monaco AP: Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection. Transplantation 43:725-730, 1987
    • (1987) Transplantation , vol.43 , pp. 725-730
    • Gotoh, M.1    Maki, T.2    Satomi, S.3    Porter, J.4    Bonner-Weir, S.5    O'Hara, C.J.6    Monaco, A.P.7
  • 24
    • 0035145780 scopus 로고    scopus 로고
    • Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids
    • Briaud I, Harmon JS, Kelpe CL, Segu VB, Poitout V: Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids. Diabetes 50:315-321, 2001
    • (2001) Diabetes , vol.50 , pp. 315-321
    • Briaud, I.1    Harmon, J.S.2    Kelpe, C.L.3    Segu, V.B.4    Poitout, V.5
  • 25
    • 0030811602 scopus 로고    scopus 로고
    • The insulin sensitizer, BRL 49653, reduces systemic fatty acid supply and utilization and tissue lipid availability in the rat
    • Oakes ND, Camilleri S, Furler SM, Chisholm DJ, Kraegen EW: The insulin sensitizer, BRL 49653, reduces systemic fatty acid supply and utilization and tissue lipid availability in the rat. Metabolism 46:935-942, 1997
    • (1997) Metabolism , vol.46 , pp. 935-942
    • Oakes, N.D.1    Camilleri, S.2    Furler, S.M.3    Chisholm, D.J.4    Kraegen, E.W.5
  • 26
    • 7844236780 scopus 로고    scopus 로고
    • Troglitazone monotherapy improves glycemic control in patients with type 2 diabetes mellitus: A randomized, controlled study: The Troglitazone Study Group
    • Fonseca VA, Valiquett TR, Huang SM, Ghazzi MN, Whitcomb RW: Troglitazone monotherapy improves glycemic control in patients with type 2 diabetes mellitus: a randomized, controlled study: the Troglitazone Study Group. J Clin Endocrinol Metab 83:3169-3176, 1998
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3169-3176
    • Fonseca, V.A.1    Valiquett, T.R.2    Huang, S.M.3    Ghazzi, M.N.4    Whitcomb, R.W.5
  • 27
    • 0035029876 scopus 로고    scopus 로고
    • Thiazolidinediones increase plasma-adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability
    • Oakes ND, Thalen PG, Jacinto SM, Ljung B: Thiazolidinediones increase plasma-adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability. Diabetes 50:1158-1165, 2001
    • (2001) Diabetes , vol.50 , pp. 1158-1165
    • Oakes, N.D.1    Thalen, P.G.2    Jacinto, S.M.3    Ljung, B.4
  • 28
    • 0035054634 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR) gamma and retinoid X receptor (RXR) agonists have complementary effects on glucose and lipid metabolism in human skeletal muscle
    • Cha BS, Ciaraldi TP, Carter L: Peroxisome proliferator-activated receptor (PPAR) gamma and retinoid X receptor (RXR) agonists have complementary effects on glucose and lipid metabolism in human skeletal muscle. Diabetologia 44:444-452, 2001
    • (2001) Diabetologia , vol.44 , pp. 444-452
    • Cha, B.S.1    Ciaraldi, T.P.2    Carter, L.3
  • 29
  • 31
    • 15444348663 scopus 로고    scopus 로고
    • Impaired β-cell function and deposition of fat droplets in the pancreas as a consequence of hypertriglyceridemia in OLETF rat, a model of spontaneous NIDDM
    • Man ZW, Zhu M, Noma Y, Toide K, Sato T, Asahi Y, Hirashima T, Mori S, Kawano K, Mizuno A, Sano T, Shima K: Impaired β-cell function and deposition of fat droplets in the pancreas as a consequence of hypertriglyceridemia in OLETF rat, a model of spontaneous NIDDM. Diabetes 46:1718-1724, 1997
    • (1997) Diabetes , vol.46 , pp. 1718-1724
    • Man, Z.W.1    Zhu, M.2    Noma, Y.3    Toide, K.4    Sato, T.5    Asahi, Y.6    Hirashima, T.7    Mori, S.8    Kawano, K.9    Mizuno, A.10    Sano, T.11    Shima, K.12
  • 32
    • 0033549840 scopus 로고    scopus 로고
    • Drug treatment of lipid disorders
    • Knopp RH: Drug treatment of lipid disorders. N Engl J Med 341:498-511, 1999
    • (1999) N Engl J Med , vol.341 , pp. 498-511
    • Knopp, R.H.1
  • 33
    • 0035943681 scopus 로고    scopus 로고
    • Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha: PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expression
    • Lawrence JW, Li Y, Chen S, DeLuca JG: Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha: PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expression. J Biol Chem 276:31521-31527, 2001
    • (2001) J Biol Chem , vol.276 , pp. 31521-31527
    • Lawrence, J.W.1    Li, Y.2    Chen, S.3    DeLuca, J.G.4
  • 35
    • 0029007068 scopus 로고
    • Decreasing triglyceride by gemfibrozil therapy does not affect the glucoregulatory or antilipolytic effect of insulin in nondiabetic subjects with mild hypertriglyceridemia
    • Sane T, Knudsen P, Vuorinen-Markkola H, Yki-Jarvinen H, Taskinen MR: Decreasing triglyceride by gemfibrozil therapy does not affect the glucoregulatory or antilipolytic effect of insulin in nondiabetic subjects with mild hypertriglyceridemia. Metabolism 44:589-596, 1995
    • (1995) Metabolism , vol.44 , pp. 589-596
    • Sane, T.1    Knudsen, P.2    Vuorinen-Markkola, H.3    Yki-Jarvinen, H.4    Taskinen, M.R.5
  • 36
    • 0029910102 scopus 로고    scopus 로고
    • Effects of gemfibrozil therapy on glucose tolerance, insulin sensitivity and plasma plasminogen activator inhibitor activity in hypertriglyceridaemia
    • Asplund-Carlson A: Effects of gemfibrozil therapy on glucose tolerance, insulin sensitivity and plasma plasminogen activator inhibitor activity in hypertriglyceridaemia. J Cardiovasc Risk 3:385-390, 1996
    • (1996) J Cardiovasc Risk , vol.3 , pp. 385-390
    • Asplund-Carlson, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.