-
1
-
-
0033046220
-
Mechanisms of phagocytosis in macrophages
-
Aderem, A. and Underhill, D. M. (1999) Mechanisms of phagocytosis in macrophages. Annu. Rev. Immunol. 17, 593-623.
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 593-623
-
-
Aderem, A.1
Underhill, D.M.2
-
2
-
-
3142724031
-
Toll-like receptor signalling
-
Akira, S. and Takeda, K. (2004) Toll-like receptor signalling. Nat. Rev. Immunol. 4, 499-511.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
3
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira, S., Uematsu, S., and Takeuchi, O. (2006) Pathogen recognition and innate immunity. Cell 124, 783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
4
-
-
10344259136
-
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter
-
Andrejeva, J., Childs, K. S., Young, D. F., Carlos, T. S., Stock, N., et al. (2004) The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter. Proc. Natl. Acad. Sci. USA 101, 17264-17269.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 17264-17269
-
-
Andrejeva, J.1
Childs, K.S.2
Young, D.F.3
Carlos, T.S.4
Stock, N.5
-
5
-
-
3042606427
-
Cell signals transduced by complement
-
Bohana-Kashtan, O., Zipoen, L., Donin, N., Kraus, S., and Fishetson, Z. (2004) Cell signals transduced by complement. Mol. Immunol. 41, 583-597.
-
(2004)
Mol. Immunol.
, vol.41
, pp. 583-597
-
-
Bohana-Kashtan, O.1
Zipoen, L.2
Donin, N.3
Kraus, S.4
Fishetson, Z.5
-
6
-
-
0037108109
-
Current molecular models for NADPH oxidase regulation by Rac GTPase
-
Bokoch, G. M. and Diebold, B. A. (2002) Current molecular models for NADPH oxidase regulation by Rac GTPase. Blood 100, 2692-2696.
-
(2002)
Blood
, vol.100
, pp. 2692-2696
-
-
Bokoch, G.M.1
Diebold, B.A.2
-
7
-
-
33244497571
-
Dectin-1: A signalling non-TLR pattern-recognition receptor
-
Brown, G D. (2006) Dectin-1: a signalling non-TLR pattern-recognition receptor. Nat. Rev. Immunol. 6, 33-43.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 33-43
-
-
Brown, G.D.1
-
8
-
-
0028564917
-
Mapping of the C5a receptor signal transduction network in human neutrophils
-
Buhl, A. M., Avdi, N., Worthen, G S., and Johnson, G. L. (1994) Mapping of the C5a receptor signal transduction network in human neutrophils. Proc. Natl. Acad. Sci. USA 91, 9190-9194.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9190-9194
-
-
Buhl, A.M.1
Avdi, N.2
Worthen, G.S.3
Johnson, G.L.4
-
9
-
-
0032573378
-
Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases
-
Caron, E. and Hall, A. (1998) Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science 282, 1717-1721.
-
(1998)
Science
, vol.282
, pp. 1717-1721
-
-
Caron, E.1
Hall, A.2
-
10
-
-
5444259851
-
The complement system in regulation of adaptive immunity
-
Carroll, M. C. (2004) The complement system in regulation of adaptive immunity. Nat. Immunol. 5, 981-986.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 981-986
-
-
Carroll, M.C.1
-
11
-
-
0035887313
-
A WASp-VASP complex regulates actin polymerization at the plasma membrane
-
Castellano, F., Le Clainche, C., Patin, D., Carlier, M. F., and Chavrier, P. (2001) A WASp-VASP complex regulates actin polymerization at the plasma membrane. EMBO J. 20, 5603-5614.
-
(2001)
EMBO J.
, vol.20
, pp. 5603-5614
-
-
Castellano, F.1
Le Clainche, C.2
Patin, D.3
Carlier, M.F.4
Chavrier, P.5
-
12
-
-
23144449789
-
Ubiquitin signalling in the NF-kappaB pathway
-
Chen, Z. J. (2005) Ubiquitin signalling in the NF-kappaB pathway. Nat. Cell Biol. 7, 758-765.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 758-765
-
-
Chen, Z.J.1
-
13
-
-
0033555931
-
A requirement for phosphatidylinositol 3-kinase in pseudopod extension
-
Cox, D., Tseng, C. C., Bjekic, G., and Greenberg, S. (1999) A requirement for phosphatidylinositol 3-kinase in pseudopod extension. J. Biol. Chem. 274, 1240-1247.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1240-1247
-
-
Cox, D.1
Tseng, C.C.2
Bjekic, G.3
Greenberg, S.4
-
14
-
-
0030829551
-
A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages
-
Crowley, M. T., Costello, P. S., Fitzer-Attas, C. J., Turner, M., Meng, F., et al. (1997) A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages. J. Exp. Med. 186, 1027-1039.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1027-1039
-
-
Crowley, M.T.1
Costello, P.S.2
Fitzer-Attas, C.J.3
Turner, M.4
Meng, F.5
-
15
-
-
27744561393
-
Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation
-
Cusson-Hermance, N., Khurana, S., Lee, T. H., Fitzgerald, K.A., and Kelliher, M. A. (2005) Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation. J. Biol. Chem. 280, 36560-36566.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36560-36566
-
-
Cusson-Hermance, N.1
Khurana, S.2
Lee, T.H.3
Fitzgerald, K.A.4
Kelliher, M.A.5
-
16
-
-
0034644474
-
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., et al. (2000) Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 103, 351-361.
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
Yang, L.4
Braun, A.5
-
17
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in sabnonella-infected macrophages
-
Franchi, L., Amer, A., Body-Malapel, M., Kanneganti, T. D., Ozoren, N., et al. (2006) Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in sabnonella-infected macrophages. Nat. Immunol. 7, 576-582.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.D.4
Ozoren, N.5
-
18
-
-
0037067649
-
Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages
-
Gagnon, E., Duclos, S., Rondeau, C., Chevet, E., Cameron, P. H., et al. (2002) Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell 110, 119-131.
-
(2002)
Cell
, vol.110
, pp. 119-131
-
-
Gagnon, E.1
Duclos, S.2
Rondeau, C.3
Chevet, E.4
Cameron, P.H.5
-
19
-
-
0038558249
-
Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2
-
Gantner, B. N., Simmons, R. M., Canavera, S. J., Akira, S., and Underhill, D. M. (2003) Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J. Exp. Med. 197, 1107-1117.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1107-1117
-
-
Gantner, B.N.1
Simmons, R.M.2
Canavera, S.J.3
Akira, S.4
Underhill, D.M.5
-
20
-
-
17644423119
-
Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility
-
Garlanda, C., Bottazzi, B., Bastone, A., and Mantovani, A. (2005) Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility. Annu. Rev. Immunol. 23, 337-366.
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 337-366
-
-
Garlanda, C.1
Bottazzi, B.2
Bastone, A.3
Mantovani, A.4
-
21
-
-
5144222255
-
Complement: A unique innate immune sensor for danger signals
-
Gasque, P. (2004) Complement: a unique innate immune sensor for danger signals. Mol. Immunol. 41, 1089-1098.
-
(2004)
Mol. Immunol.
, vol.41
, pp. 1089-1098
-
-
Gasque, P.1
-
22
-
-
17944380130
-
CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri
-
Girardin, S. E., Tournebize, R., Mavris, M., Page, A. L., Li, X., et al. (2001) CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. EMBO Rep. 2, 736-742.
-
(2001)
EMBO Rep.
, vol.2
, pp. 736-742
-
-
Girardin, S.E.1
Tournebize, R.2
Mavris, M.3
Page, A.L.4
Li, X.5
-
23
-
-
33744791510
-
Essential role of mda-5 in type I IFN responses to polyriboinosinic: Polyribocytidylic acid and encephalomyocarditis picornavirus
-
Gitlin, L., Barchet, W., Gilfillan, S., Cella, M., Beutler, B., et al. (2006) Essential role of mda-5 in type I IFN responses to polyriboinosinic: polyribocytidylic acid and encephalomyocarditis picornavirus. Proc. Natl. Acad. Sci. USA 103, 8459-8464.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8459-8464
-
-
Gitlin, L.1
Barchet, W.2
Gilfillan, S.3
Cella, M.4
Beutler, B.5
-
24
-
-
0032753490
-
Modular components of phagocytosis
-
Greenberg, S. (1999) Modular components of phagocytosis. J. Leukoc. Biol. 66, 712-717.
-
(1999)
J. Leukoc. Biol.
, vol.66
, pp. 712-717
-
-
Greenberg, S.1
-
25
-
-
33747036397
-
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity
-
Gross, O., Gewies, A., Finger, K., Schafer, M., Sparwasser, T., et al. (2006) Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature 442, 651-656.
-
(2006)
Nature
, vol.442
, pp. 651-656
-
-
Gross, O.1
Gewies, A.2
Finger, K.3
Schafer, M.4
Sparwasser, T.5
-
26
-
-
17644388462
-
Role of C5a in inflammatory responses
-
Guo, R. F. and Ward, P. A. (2005) Role of C5a in inflammatory responses. Annu. Rev. Immunol. 23, 821-852.
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 821-852
-
-
Guo, R.F.1
Ward, P.A.2
-
27
-
-
30544451546
-
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
-
Hacker, H., Redecke, V., Blagoev, B., Kratchmarova, I., Hsu, L. C., et al. (2006) Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 439, 204-207.
-
(2006)
Nature
, vol.439
, pp. 204-207
-
-
Hacker, H.1
Redecke, V.2
Blagoev, B.3
Kratchmarova, I.4
Hsu, L.C.5
-
28
-
-
33644990678
-
Requirements for Vav guanine nucleotide exchange factors and Rho GTPases in FcgammaR- and complement-mediated phagocytosis
-
Hall, A. B., Gakidis, M. A., Glogauer, M., Wilsbacher, J. L., Gao, S., et al. (2006) Requirements for Vav guanine nucleotide exchange factors and Rho GTPases in FcgammaR- and complement-mediated phagocytosis. Immunity 24, 305-316.
-
(2006)
Immunity
, vol.24
, pp. 305-316
-
-
Hall, A.B.1
Gakidis, M.A.2
Glogauer, M.3
Wilsbacher, J.L.4
Gao, S.5
-
29
-
-
22544471801
-
Complement and Toll-like receptors: Key regulators of adaptive immune responses
-
Hawlisch, H. and Kohl, J. (2006) Complement and Toll-like receptors: key regulators of adaptive immune responses. Mol. Immunol. 43, 13-21.
-
(2006)
Mol. Immunol.
, vol.43
, pp. 13-21
-
-
Hawlisch, H.1
Kohl, J.2
-
30
-
-
33750976374
-
5′-Triphosphate RNA is the ligand for RIG-I
-
Hornung, V., Ellegast, J., Kim, S., Brzozka, K., Jung, A., et al. (2006) 5′-Triphosphate RNA is the ligand for RIG-I. Science 314, 994-997.
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzozka, K.4
Jung, A.5
-
31
-
-
17644366913
-
NOD-LRR proteins: Role in host-microbial interactions and inflammatory disease
-
Inohara, Chamaillard, McDonald, C., and Nunez, G. (2005) NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu. Rev. Biochem. 74, 355-383.
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 355-383
-
-
Inohara1
Chamaillard2
McDonald, C.3
Nunez, G.4
-
32
-
-
29244471275
-
A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA
-
Ishii, K. J., Coban, C., Kato, H., Takahashi, K., Torii, Y., et al. (2006) A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat. Immunol. 7, 40-48.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 40-48
-
-
Ishii, K.J.1
Coban, C.2
Kato, H.3
Takahashi, K.4
Torii, Y.5
-
33
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki, A. and Medzhitov, R. (2004) Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5, 987-995.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
35
-
-
33646908228
-
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
-
Kagan, J. C. and Medzhitov, R. (2006) Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 125, 943-955.
-
(2006)
Cell
, vol.125
, pp. 943-955
-
-
Kagan, J.C.1
Medzhitov, R.2
-
36
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
Kanneganti, T. D., Ozoren, N., Body-Malapel, M., Amer, A., Park, J. H., et al. (2006) Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 440, 233-236.
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.H.5
-
37
-
-
22544455673
-
Cell type-specific involvement of RIG-I in antiviral response
-
Kato, H., Sato, S., Yoneyama, M., Yamamoto, M., Uematsu, S., et al. (2005) Cell type-specific involvement of RIG-I in antiviral response. Immunity 23, 19-28.
-
(2005)
Immunity
, vol.23
, pp. 19-28
-
-
Kato, H.1
Sato, S.2
Yoneyama, M.3
Yamamoto, M.4
Uematsu, S.5
-
38
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato, H., Takeuchi, O., Sato, S., Yoneyama, M., Yamamoto, M., et al. (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441, 101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
-
39
-
-
31344461659
-
Innate immune recognition of viral infection
-
Kawai, T. and Akira, S. (2006a) Innate immune recognition of viral infection. Nat. Immunol. 7, 131-137.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 131-137
-
-
Kawai, T.1
Akira, S.2
-
41
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai, T., Takahashi, K., Sato, S., Coban, C., Kumar, H., et al. (2005) IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6, 981-988.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
-
42
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi, K. S., Chamaillard, M., Ogura, Y., Henegariu, O., Inohara, N., et al. (2005) Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307, 731-734.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
-
43
-
-
0033552215
-
CR3, FcgammaRIIA and FcgammaRIIIB induce activation of the respiratory burst in human neutrophils: The role of intracellular Ca(2+), phospholipase D and tyrosine phosphorytation
-
Lofgren, R., Serrander, L., Forsberg, M., Wilsson, A., Wasteson, A., et al. (1999) CR3, FcgammaRIIA and FcgammaRIIIB induce activation of the respiratory burst in human neutrophils: the role of intracellular Ca(2+), phospholipase D and tyrosine phosphorytation. Biochim. Biophys. Acta 1452, 46-59.
-
(1999)
Biochim. Biophys. Acta
, vol.1452
, pp. 46-59
-
-
Lofgren, R.1
Serrander, L.2
Forsberg, M.3
Wilsson, A.4
Wasteson, A.5
-
44
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., et al. (2006) Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440, 228-232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
-
45
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon, F., Petrilli, V., Mayor, A., Tardivel, A., and Tschopp, J. (2006) Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440, 237-241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
46
-
-
2542457495
-
Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
-
Martinon, F. and Tschopp, J. (2004) Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117, 561-574.
-
(2004)
Cell
, vol.117
, pp. 561-574
-
-
Martinon, F.1
Tschopp, J.2
-
47
-
-
22444433175
-
NLRs join TLRs as innate sensors of pathogens
-
Martinon, F. and Tschopp, J. (2005) NLRs join TLRs as innate sensors of pathogens. Trends Immunol. 26, 447-454.
-
(2005)
Trends Immunol.
, vol.26
, pp. 447-454
-
-
Martinon, F.1
Tschopp, J.2
-
48
-
-
0035067475
-
Phagocytosis and the actin cytoskeleton
-
May, R. C. and Machesky, L. M. (2001) Phagocytosis and the actin cytoskeleton. J. Cell Sci. 114, 1061-1077.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 1061-1077
-
-
May, R.C.1
Machesky, L.M.2
-
49
-
-
0033790639
-
Involvement of the Arp2/3 complex in phagocytosis mediated by FcgammaR or CR3
-
May, R. C., Caron, E., Hall, A., and Machesky, L. M. (2000) Involvement of the Arp2/3 complex in phagocytosis mediated by FcgammaR or CR3. Nat. Cell. Biol. 2, 246-248.
-
(2000)
Nat. Cell. Biol.
, vol.2
, pp. 246-248
-
-
May, R.C.1
Caron, E.2
Hall, A.3
Machesky, L.M.4
-
50
-
-
0037066502
-
Decoding the patterns of self and nonself by the innate immune system
-
Medzhitov, R. and Janeway, C. A., Jr. (2002) Decoding the patterns of self and nonself by the innate immune system. Science 296, 298-300.
-
(2002)
Science
, vol.296
, pp. 298-300
-
-
Medzhitov, R.1
Janeway Jr., C.A.2
-
51
-
-
2442642691
-
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation
-
Meylan, E., Burns, K., Hofmann, K., Blancheteau, V., Martinon, F., et al. (2004) RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. Nat. Immunol. 5, 503-507.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 503-507
-
-
Meylan, E.1
Burns, K.2
Hofmann, K.3
Blancheteau, V.4
Martinon, F.5
-
52
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan, E., Curran, J., Hofmann, K., Moradpour, D., Binder, M., et al. (2005) Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437, 1167-1172.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
-
53
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao, E. A., Alpuche-Aranda, C. M., Dors, M., Clark, A. E., Bader, M. W., et al. (2006) Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat. Immunol. 7, 569-575.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
-
54
-
-
33645843633
-
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
-
Molofsky, A. B., Byrne, B. G., Whitfield, N. N., Madigan, C. A., Fuse, E. T., et al. (2006) Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection. J. Exp. Med. 203, 1093-1104.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1093-1104
-
-
Molofsky, A.B.1
Byrne, B.G.2
Whitfield, N.N.3
Madigan, C.A.4
Fuse, E.T.5
-
55
-
-
28544452195
-
A role for the phagosome in cytokine secretion
-
Murray, R. Z., Kay, J. G., Sangermani, D. G., and Stow, J. L. (2005) A role for the phagosome in cytokine secretion. Science 310, 1492-1495.
-
(2005)
Science
, vol.310
, pp. 1492-1495
-
-
Murray, R.Z.1
Kay, J.G.2
Sangermani, D.G.3
Stow, J.L.4
-
56
-
-
3142514390
-
Signaling and membrane dynamics during phagocytosis: Many roads lead to the phagos(R)ome
-
Niedergang, F. and Chavrier, P. (2004) Signaling and membrane dynamics during phagocytosis: many roads lead to the phagos(R)ome. Curr. Opin. Cell Biol. 16, 422-428.
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 422-428
-
-
Niedergang, F.1
Chavrier, P.2
-
57
-
-
30544447047
-
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
-
Oganesyan, G., Saha, S. K., Guo, B., He, J. Q., Shahangian, A., et al. (2006) Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature 439, 208-211.
-
(2006)
Nature
, vol.439
, pp. 208-211
-
-
Oganesyan, G.1
Saha, S.K.2
Guo, B.3
He, J.Q.4
Shahangian, A.5
-
58
-
-
0036151650
-
C5a delays apoptosis of human neutrophils by a phosphatidylinositol 3-kinase-signaling pathway
-
Perianayagam, M. C., Balakrishnan, V. S., King, A. J., Pereira, B. J., and Jaber, B. L. (2002). C5a delays apoptosis of human neutrophils by a phosphatidylinositol 3-kinase-signaling pathway. Kidney Int. 61, 456-463.
-
(2002)
Kidney Int.
, vol.61
, pp. 456-463
-
-
Perianayagam, M.C.1
Balakrishnan, V.S.2
King, A.J.3
Pereira, B.J.4
Jaber, B.L.5
-
59
-
-
1242292337
-
C5a delays apoptosis of human neutrophils via an extracellular signal-regulated kinase and Bad-mediated signalling pathway
-
Perianayagam, M. C., Balakrishnan, V. S., Pereira, B. J., and Jaber, B. L. (2004) C5a delays apoptosis of human neutrophils via an extracellular signal-regulated kinase and Bad-mediated signalling pathway. Eur. J. Clin. Invest. 34, 50-56.
-
(2004)
Eur. J. Clin. Invest.
, vol.34
, pp. 50-56
-
-
Perianayagam, M.C.1
Balakrishnan, V.S.2
Pereira, B.J.3
Jaber, B.L.4
-
60
-
-
33645888404
-
CREB transcription factor modulates Bcl2 transcription in response to C5a in HL-60-derived neutrophils
-
Perianayagam, M. C., Madias, N. E., Pereira, B. J., and Jaber, B. L. (2006) CREB transcription factor modulates Bcl2 transcription in response to C5a in HL-60-derived neutrophils. Eur. J. Clin. Invest. 36, 353-361.
-
(2006)
Eur. J. Clin. Invest.
, vol.36
, pp. 353-361
-
-
Perianayagam, M.C.1
Madias, N.E.2
Pereira, B.J.3
Jaber, B.L.4
-
61
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates
-
Pichlmair, A., Schulz, O., Tan, C. P., Naslund, T. I., Liljestrom, P., et al. (2006) RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates. Science 314, 997-1001.
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Naslund, T.I.4
Liljestrom, P.5
-
62
-
-
32944478316
-
Translating innate immunity into immunological memory: Implications for vaccine development
-
Pulendran, B. and Ahmed, R. (2006) Translating innate immunity into immunological memory: implications for vaccine development. Cell 124, 849-863.
-
(2006)
Cell
, vol.124
, pp. 849-863
-
-
Pulendran, B.1
Ahmed, R.2
-
63
-
-
33645791082
-
Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity
-
Ren, T., Zamboni, D. S., Roy, C. R., Dietrich, W. F., and Vance, R. E. (2006) Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity. PLoS Pathog. 2, e18.
-
(2006)
PLoS Pathog
, vol.2
-
-
Ren, T.1
Zamboni, D.S.2
Roy, C.R.3
Dietrich, W.F.4
Vance, R.E.5
-
64
-
-
20244363662
-
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins
-
Rogers, N. C., Stack, E. C., Edwards, A. D., Nolte, M. A., Schulz, O., et al. (2005) Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity 22, 507-517.
-
(2005)
Immunity
, vol.22
, pp. 507-517
-
-
Rogers, N.C.1
Stack, E.C.2
Edwards, A.D.3
Nolte, M.A.4
Schulz, O.5
-
65
-
-
28544443670
-
Alphavbeta3 and macrophage colony-stimulating factor: Partners in osteoclast biology
-
Ross, F. P. and Teitelbaum, S. L. (2005) alphavbeta3 and macrophage colony-stimulating factor: partners in osteoclast biology. Immunol. Rev. 208, 88-105.
-
(2005)
Immunol. Rev.
, vol.208
, pp. 88-105
-
-
Ross, F.P.1
Teitelbaum, S.L.2
-
66
-
-
33646567507
-
The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction
-
Rowe, D. C., McGettrick, A. F., Latz, E., Monks, B. G., Gay, N. J., et al. (2006) The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction. Proc. Natl. Acad. Sci. USA 103, 6299-6304.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 6299-6304
-
-
Rowe, D.C.1
McGettrick, A.F.2
Latz, E.3
Monks, B.G.4
Gay, N.J.5
-
67
-
-
33746479050
-
Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif
-
Saha, S. K., Pietras, E. M., He, J. Q., Kang, J. R., Liu, S. Y., et al. (2006) Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif. EMBO J. 25, 3257-3263.
-
(2006)
EMBO J.
, vol.25
, pp. 3257-3263
-
-
Saha, S.K.1
Pietras, E.M.2
He, J.Q.3
Kang, J.R.4
Liu, S.Y.5
-
68
-
-
33846963844
-
Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans
-
Saijo, S., Fujikado, N., Furuta, T., Chung, S. H., Kotaki, H., et al. (2007) Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans. Nat. Immunol. 8, 39-46.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 39-46
-
-
Saijo, S.1
Fujikado, N.2
Furuta, T.3
Chung, S.H.4
Kotaki, H.5
-
69
-
-
27544434183
-
Essential function for the kinase TAK1 in innate and adaptive immune responses
-
Sato, S., Sanjo, H., Takeda, K., Ninomiya-Tsuji, J., Yamamoto, M., et al. (2005) Essential function for the kinase TAK1 in innate and adaptive immune responses. Nat. Immunol. 6, 1087-1095.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1087-1095
-
-
Sato, S.1
Sanjo, H.2
Takeda, K.3
Ninomiya-Tsuji, J.4
Yamamoto, M.5
-
70
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth, R. B., Sun, L., Ea, C. K., and Chen, Z. J. (2005) Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122, 669-682.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
71
-
-
0031657551
-
How cells respond to interferons
-
Stark, G. R., Kerr, I. M., Williams, B. R., Silverman, R. H., and Schreiber, R. D. (1998) How cells respond to interferons. Annu. Rev. Biochem. 67, 227-264.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
72
-
-
33244472793
-
Signalling pathways and molecular interactions of NOD1 and NOD2
-
Strober, W., Murray, P. J., Kitani, A., and Watanabe, T. (2006) Signalling pathways and molecular interactions of NOD1 and NOD2. Nat. Rev. Immunol. 6, 9-20.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 9-20
-
-
Strober, W.1
Murray, P.J.2
Kitani, A.3
Watanabe, T.4
-
73
-
-
33646592188
-
The specific and essential role of MAVS in antiviral innate immune responses
-
Sun, Q., Sun, L., Liu, H. H., Chen, X., Seth, R. B., et al. (2006) The specific and essential role of MAVS in antiviral innate immune responses. Immunity 24, 633-642.
-
(2006)
Immunity
, vol.24
, pp. 633-642
-
-
Sun, Q.1
Sun, L.2
Liu, H.H.3
Chen, X.4
Seth, R.B.5
-
74
-
-
10044234242
-
The coordination of signaling during Fc receptor-mediated phagocytosis
-
Swanson, J. A. and Hoppe, A. D. (2004) The coordination of signaling during Fc receptor-mediated phagocytosis. J. Leukoc. Biol. 76, 1093-1103.
-
(2004)
J. Leukoc. Biol.
, vol.76
, pp. 1093-1103
-
-
Swanson, J.A.1
Hoppe, A.D.2
-
75
-
-
15044345461
-
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
-
Takaoka, A., Yanai, H., Kondo, S., Duncan, G., Negishi, H., et al. (2005) Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 434, 243-249.
-
(2005)
Nature
, vol.434
, pp. 243-249
-
-
Takaoka, A.1
Yanai, H.2
Kondo, S.3
Duncan, G.4
Negishi, H.5
-
76
-
-
11844254888
-
Macrophage receptors and immune recognition
-
Taylor, P. R., Martinez-Pomares, L., Stacey, M., Lin, H. H., Brown, G. D., et al. (2005) Macrophage receptors and immune recognition. Annu. Rev. Immunol. 23, 901-944.
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 901-944
-
-
Taylor, P.R.1
Martinez-Pomares, L.2
Stacey, M.3
Lin, H.H.4
Brown, G.D.5
-
77
-
-
33846962860
-
Dectin-1 is required for beta-glucan recognition and control of fungal infection
-
Taylor, P. R., Tsoni, S. V. Willment, J. A., Dennehy, K. M. Rosas, M., et al. (2007) Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat. Immunol. 8, 31-38.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 31-38
-
-
Taylor, P.R.1
Tsoni, S.V.2
Willment, J.A.3
Dennehy, K.M.4
Rosas, M.5
-
78
-
-
33344476398
-
CATERPILLERs, pyrin and hereditary immunological disorders
-
Ting, J. P., Kastner, D. L., and Hoffman, H. M. (2006) CATERPILLERs, pyrin and hereditary immunological disorders. Nat. Rev. Immunol. 6, 183-195.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 183-195
-
-
Ting, J.P.1
Kastner, D.L.2
Hoffman, H.M.3
-
79
-
-
26244461724
-
Quantitative and dynamic assessment of the contribution of the ER to phagosome formation
-
Touret, N., Paroutis, P., Terebiznik M., Harrison, R. E., Trombetta, S., et al. (2005) Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell 123, 157-170.
-
(2005)
Cell
, vol.123
, pp. 157-170
-
-
Touret, N.1
Paroutis, P.2
Terebiznik, M.3
Harrison, R.E.4
Trombetta, S.5
-
80
-
-
0037312509
-
NALPs: A novel protein family involved in inflammation
-
Tschopp, J., Martinon, F., and Burns, K. (2003) NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol. 4, 95-104.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 95-104
-
-
Tschopp, J.1
Martinon, F.2
Burns, K.3
-
81
-
-
0036216769
-
Phagocytosis of microbes: Complexity in action
-
Underhill, D. M. and Ozinsky, A. (2002) Phagocytosis of microbes: complexity in action. Annu. Rev. Immunol. 20, 825-852.
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 825-852
-
-
Underhill, D.M.1
Ozinsky, A.2
-
82
-
-
27144521657
-
Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production
-
Underhill, D. M., Rossnagle, E., Lowell, C. A., and Simmons, R. M. (2005) Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. Blood 106, 2543-2550.
-
(2005)
Blood
, vol.106
, pp. 2543-2550
-
-
Underhill, D.M.1
Rossnagle, E.2
Lowell, C.A.3
Simmons, R.M.4
-
83
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang, C., Deng, L., Hong, M., Akkaraju, G R., Inoue, J., et al. (2001) TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412, 346-351.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.5
-
84
-
-
33645958613
-
TIR, CARD and PYRIN: Three domains for an antimicrobial triad
-
Werts, C., Girardin, S. E., and Philpott, D. J. (2006) TIR, CARD and PYRIN: three domains for an antimicrobial triad. Cell Death Differ. 13, 798-815.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 798-815
-
-
Werts, C.1
Girardin, S.E.2
Philpott, D.J.3
-
85
-
-
33645845142
-
Phosphatidylserine recognition by phagocytes: A view to a kill
-
Wu, Y., Tibrewal, N., and Birge, R. B. (2006) Phosphatidylserine recognition by phagocytes: a view to a kill. Trends Cell Biol. 16, 189-197.
-
(2006)
Trends Cell Biol.
, vol.16
, pp. 189-197
-
-
Wu, Y.1
Tibrewal, N.2
Birge, R.B.3
-
86
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-beta signaling
-
Xu, L. G., Wang, Y. Y., Han, K. J., Li, L. Y., Zhai, Z., et al. (2005) VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol. Cells 19, 727-740.
-
(2005)
Mol. Cells
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
Wang, Y.Y.2
Han, K.J.3
Li, L.Y.4
Zhai, Z.5
-
87
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama, M., Kikuchi, M., Natsukawa, T., Shinobu, N., Imaizumi, T., et al. (2004) The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5, 730-737.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
|