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This work was generously supported by a Cancer Research Campaign (UK) program grant. E.C. was the recipient of a Training and Mobility of Researchers fellowship from the European Union. We thank B. Seed for human FcγRIIA, A. Law for CD11b and CD18, B. Wren for purified toxin B, and C D. Nobes and L. M. Machesky for their constructive help and useful discussions throughout this work.
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