-
1
-
-
0012431804
-
Report of the expert committee on the diagnosis and classification of diabetes mellitus
-
Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
-
Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2003;26:5-20
-
(2003)
Diabetes Care
, vol.26
, pp. 5-20
-
-
-
2
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
-
The Diabetes Control and Complications Trial Research Group
-
The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977-986
-
(1993)
N Engl J Med
, vol.329
, pp. 977-986
-
-
-
3
-
-
0032511583
-
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
-
UK Prospective Diabetes Study (UKPDS) Group
-
UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-853
-
(1998)
Lancet
, vol.352
, pp. 837-853
-
-
-
4
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001;414:813-820
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
5
-
-
10644259663
-
From hyperglycemia to diabetic kidney disease: The role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines
-
Schrijvers BF, De Vriese AS, Flyvbjerg A. From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines. Endocr Rev 2004;25(6):971-1010
-
(2004)
Endocr Rev
, vol.25
, Issue.6
, pp. 971-1010
-
-
Schrijvers, B.F.1
De Vriese, A.S.2
Flyvbjerg, A.3
-
6
-
-
0037327402
-
Oxidative stress and diabetic neuropathy: A new understanding of an old problem
-
Feldman EL. Oxidative stress and diabetic neuropathy: a new understanding of an old problem. J Clin Invest 2003;111:431-433
-
(2003)
J Clin Invest
, vol.111
, pp. 431-433
-
-
Feldman, E.L.1
-
7
-
-
1842526645
-
Microvascular complications of diabetes
-
He Z, King GL. Microvascular complications of diabetes. Endocrinol Metab Clin North Am 2004;33(1):215-238
-
(2004)
Endocrinol Metab Clin North Am
, vol.33
, Issue.1
, pp. 215-238
-
-
He, Z.1
King, G.L.2
-
8
-
-
0031848378
-
Effects of diabetes and level of glycemia on all-cause and cardiovascular mortality. The San Antonio Heart Study
-
Wei M, Gaskill SP, Haffner SM, Stern MP. Effects of diabetes and level of glycemia on all-cause and cardiovascular mortality. The San Antonio Heart Study. Diabetes Care 1998;7:1167-1172
-
(1998)
Diabetes Care
, vol.7
, pp. 1167-1172
-
-
Wei, M.1
Gaskill, S.P.2
Haffner, S.M.3
Stern, M.P.4
-
9
-
-
8644267972
-
Hyperglycemia-induced oxidative stress in diabetic complications
-
King GL, Loeken MR. Hyperglycemia-induced oxidative stress in diabetic complications. Histochem Cell Biol 2004;122(4):333-338
-
(2004)
Histochem Cell Biol
, vol.122
, Issue.4
, pp. 333-338
-
-
King, G.L.1
Loeken, M.R.2
-
10
-
-
0037223174
-
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
-
Mokdad AH, Ford ES, Bowman BA, Dietz WH, Vinicor F, Bales VS, Marks JS. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 2003;289(1):76-79
-
(2003)
JAMA
, vol.289
, Issue.1
, pp. 76-79
-
-
Mokdad, A.H.1
Ford, E.S.2
Bowman, B.A.3
Dietz, W.H.4
Vinicor, F.5
Bales, V.S.6
Marks, J.S.7
-
11
-
-
20044376702
-
The pathobiology of diabetic complications: A unifying mechanism
-
Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes 2005;54:1615-1625
-
(2005)
Diabetes
, vol.54
, pp. 1615-1625
-
-
Brownlee, M.1
-
12
-
-
0033857531
-
The missing link: A single unifying mechanism for diabetic complications
-
Nishikawa T, Edelstein D, Brownlee M. The missing link: a single unifying mechanism for diabetic complications. Kidney International 2000;77:26-30
-
(2000)
Kidney International
, vol.77
, pp. 26-30
-
-
Nishikawa, T.1
Edelstein, D.2
Brownlee, M.3
-
13
-
-
21044443182
-
Diabetic vascular complications: Pathophysiology, biochemical basis and potential therapeutic strategy
-
Yamagishi S, Imaizumi T. Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy. Curr Pharm Des 2005;11:2279-2299
-
(2005)
Curr Pharm Des
, vol.11
, pp. 2279-2299
-
-
Yamagishi, S.1
Imaizumi, T.2
-
14
-
-
0037184495
-
Molecular understanding of hyperglycemia's adverse effects for diabetic complications
-
Sheetz MJ, King GL. Molecular understanding of hyperglycemia's adverse effects for diabetic complications. JAMA 2002;288:2579-2588
-
(2002)
JAMA
, vol.288
, pp. 2579-2588
-
-
Sheetz, M.J.1
King, G.L.2
-
15
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
-
Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I, Brownlee M. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000;404:787-790
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
Yamagishi, S.4
Matsumura, T.5
Kaneda, Y.6
Yorek, M.A.7
Beebe, D.8
Oates, P.J.9
Hammes, H.P.10
Giardino, I.11
Brownlee, M.12
-
16
-
-
18844369302
-
Role of Aldose Reductase and Oxidative Damage in Diabetes and the Consequent Potential for Therapeutic Options
-
Srivastava SK, Ramana KV, Bhatnagar A. Role of Aldose Reductase and Oxidative Damage in Diabetes and the Consequent Potential for Therapeutic Options. Endocr Rev 2005;26:380-392
-
(2005)
Endocr Rev
, vol.26
, pp. 380-392
-
-
Srivastava, S.K.1
Ramana, K.V.2
Bhatnagar, A.3
-
17
-
-
0034122558
-
Surface oxidase and oxidative stress propagation in aging
-
Morre DM, Lenaz G, Morre DJ. Surface oxidase and oxidative stress propagation in aging. J Exp Biol 2000;203:1513-1521
-
(2000)
J Exp Biol
, vol.203
, pp. 1513-1521
-
-
Morre, D.M.1
Lenaz, G.2
Morre, D.J.3
-
18
-
-
0037046214
-
Mechanisms of increased vascular superoxide production in human diabetes mellitus: Role of NAD(P)H oxidase and endothelial nitric oxide synthase
-
Guzik TJ, Mussa S, Gastaldi D, Sadowski J, Ratnatunga C, Pillai R, Channon KM. Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation 2002;105:1656-1662
-
(2002)
Circulation
, vol.105
, pp. 1656-1662
-
-
Guzik, T.J.1
Mussa, S.2
Gastaldi, D.3
Sadowski, J.4
Ratnatunga, C.5
Pillai, R.6
Channon, K.M.7
-
20
-
-
0141534204
-
Stimulation of PAI-1 and adipokines by glucose in human adipose tissue in vitro
-
He G, Bruun JM, Lihn AS, Pedersen SB, Richelsen B. Stimulation of PAI-1 and adipokines by glucose in human adipose tissue in vitro. Biochem Biophys Res Commun 2003;310:878-883
-
(2003)
Biochem Biophys Res Commun
, vol.310
, pp. 878-883
-
-
He, G.1
Bruun, J.M.2
Lihn, A.S.3
Pedersen, S.B.4
Richelsen, B.5
-
21
-
-
3442900756
-
Inhibition of aldose reductase attenuates TNF-alpha-induced expression of adhesion molecules in endothelial cells
-
Ramana KV, Bhatnagar A, Srivastava SK. Inhibition of aldose reductase attenuates TNF-alpha-induced expression of adhesion molecules in endothelial cells. FASEB J 2004;18:1209-1218
-
(2004)
FASEB J
, vol.18
, pp. 1209-1218
-
-
Ramana, K.V.1
Bhatnagar, A.2
Srivastava, S.K.3
-
22
-
-
0037199974
-
Aldose reductase mediates mitogenic signalling in vascular smooth muscle cells
-
Ramana KV, Chandra D, Srivastava S, Bhatnagar A, Aggarwal BB, Srivastava SK. Aldose reductase mediates mitogenic signalling in vascular smooth muscle cells. J Biol Chem 2002;277:32063-32070
-
(2002)
J Biol Chem
, vol.277
, pp. 32063-32070
-
-
Ramana, K.V.1
Chandra, D.2
Srivastava, S.3
Bhatnagar, A.4
Aggarwal, B.B.5
Srivastava, S.K.6
-
23
-
-
7044247670
-
Activation of nuclear factor-kappaB by hyperglycemic in vascular smooth muscle cells is regulated by aldose reductase
-
Ramana KV, Friedrich B, Srivastava S, Bhatnagar A, Srivastava SK. Activation of nuclear factor-kappaB by hyperglycemic in vascular smooth muscle cells is regulated by aldose reductase. Diabetes 2004;53:2910-2920
-
(2004)
Diabetes
, vol.53
, pp. 2910-2920
-
-
Ramana, K.V.1
Friedrich, B.2
Srivastava, S.3
Bhatnagar, A.4
Srivastava, S.K.5
-
24
-
-
0037324789
-
Role of aldose reductase in TNF-alpha-induced apoptosis of vascular endothelial cells
-
Chandra D, Ramana KV, Friedrich B, Srivastava S, Bhatnagar A, Srivastava SK. Role of aldose reductase in TNF-alpha-induced apoptosis of vascular endothelial cells. Chem Biol Interact 2003;143-144:605-612
-
(2003)
Chem Biol Interact
-
-
Chandra, D.1
Ramana, K.V.2
Friedrich, B.3
Srivastava, S.4
Bhatnagar, A.5
Srivastava, S.K.6
-
25
-
-
0037375171
-
The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes
-
Miwa K, Nakamura J, Hamada Y, Naruse K, Nakashima E, Kato K, Kasuya Y, Yasuda Y, Kamiya H, Hotta N. The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes. Diabetes Res Clin Pract 2003;60:1-9
-
(2003)
Diabetes Res Clin Pract
, vol.60
, pp. 1-9
-
-
Miwa, K.1
Nakamura, J.2
Hamada, Y.3
Naruse, K.4
Nakashima, E.5
Kato, K.6
Kasuya, Y.7
Yasuda, Y.8
Kamiya, H.9
Hotta, N.10
-
26
-
-
0742324141
-
Polyol pathway-dependent osmotic and oxidative stresses in aldose reductase-mediated apoptosis in human lens epithelial cells: Role of AOP2
-
Kubo E, Urakami T, Fatma N, Akagi Y, Singh DP. Polyol pathway-dependent osmotic and oxidative stresses in aldose reductase-mediated apoptosis in human lens epithelial cells: role of AOP2. Biochemical and Biophysical Research Communications 2004;314:1050-1056
-
(2004)
Biochemical and Biophysical Research Communications
, vol.314
, pp. 1050-1056
-
-
Kubo, E.1
Urakami, T.2
Fatma, N.3
Akagi, Y.4
Singh, D.P.5
-
27
-
-
18244420728
-
Induction of aldose reductase in cultured human microvascular endothelial cells by advanced glycation end products
-
Nakamura N, Obayashi H, Fujii M, Fukui M, Yoshimori K, Ogata M, Hasegawa G, Shigeta H, Kitagawa Y, Yoshikawa T, Kondo M, Ohta M, Nishimura M, Nishinaka T, Nishimura CY. Induction of aldose reductase in cultured human microvascular endothelial cells by advanced glycation end products. Free Radic Biol Med 2000;29:17-25
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 17-25
-
-
Nakamura, N.1
Obayashi, H.2
Fujii, M.3
Fukui, M.4
Yoshimori, K.5
Ogata, M.6
Hasegawa, G.7
Shigeta, H.8
Kitagawa, Y.9
Yoshikawa, T.10
Kondo, M.11
Ohta, M.12
Nishimura, M.13
Nishinaka, T.14
Nishimura, C.Y.15
-
29
-
-
0037336421
-
Nitric oxide regulates the polyol pathway of glucose metabolism in vascular smooth muscle cells
-
Ramana KV, Chandra D, Srivastava S, Bhatnagar A, Srivastava SK. Nitric oxide regulates the polyol pathway of glucose metabolism in vascular smooth muscle cells. FASEB J 2003;17:417-425
-
(2003)
FASEB J
, vol.17
, pp. 417-425
-
-
Ramana, K.V.1
Chandra, D.2
Srivastava, S.3
Bhatnagar, A.4
Srivastava, S.K.5
-
30
-
-
2542491269
-
Effects of angiotensin II receptor blockers, angiotensin converting enzyme inhibitors, 3-hydroxy-3-methyl glutaryl (HMG) CoA reductase inhibitors, amlodipine and epalrestat on cultured basilar artery smooth muscle cell proliferation
-
Yamaguchi T, Ida T, Hiraga M, Oishi K, Uchida MK, Echizen H. Effects of angiotensin II receptor blockers, angiotensin converting enzyme inhibitors, 3-hydroxy-3-methyl glutaryl (HMG) CoA reductase inhibitors, amlodipine and epalrestat on cultured basilar artery smooth muscle cell proliferation. Yakugaku Zasshi 2004;124:159-163
-
(2004)
Yakugaku Zasshi
, vol.124
, pp. 159-163
-
-
Yamaguchi, T.1
Ida, T.2
Hiraga, M.3
Oishi, K.4
Uchida, M.K.5
Echizen, H.6
-
31
-
-
0034869770
-
Long-term effect of epalrestat, an aldose reductase inhibitor, on the development of incipient diabetic nephropathy in Type 2 diabetic patients
-
Iso K, Tada H, Kuboki K, Inokuchi T. Long-term effect of epalrestat, an aldose reductase inhibitor, on the development of incipient diabetic nephropathy in Type 2 diabetic patients. J Diabetes Complications 2001;15:241-244
-
(2001)
J Diabetes Complications
, vol.15
, pp. 241-244
-
-
Iso, K.1
Tada, H.2
Kuboki, K.3
Inokuchi, T.4
-
32
-
-
0042975081
-
Effects of epalrestat, an aldose reductase inhibitor, on diabetic neuropathy and gastroparesis
-
Okamoto H, Nomura M, Nakaya Y, Uehara K, Saito K, Kimura M, Chikamori K, Ito S. Effects of epalrestat, an aldose reductase inhibitor, on diabetic neuropathy and gastroparesis. Intern Med 2003;42:655-664
-
(2003)
Intern Med
, vol.42
, pp. 655-664
-
-
Okamoto, H.1
Nomura, M.2
Nakaya, Y.3
Uehara, K.4
Saito, K.5
Kimura, M.6
Chikamori, K.7
Ito, S.8
-
33
-
-
0037532456
-
Effects of eparlestat on plasma levels of advanced glycation end products in patients with type 2 diabetes
-
Nakamura N, Yamazaki K, Satoh A, Urakaze M, Kobayashi M, Yamabe H, Osawa H, Shirato K, Sugawara T, Nakamura M, Tamura M, Okumura K. Effects of eparlestat on plasma levels of advanced glycation end products in patients with type 2 diabetes. In Vivo 2003;17:177-180
-
(2003)
In Vivo
, vol.17
, pp. 177-180
-
-
Nakamura, N.1
Yamazaki, K.2
Satoh, A.3
Urakaze, M.4
Kobayashi, M.5
Yamabe, H.6
Osawa, H.7
Shirato, K.8
Sugawara, T.9
Nakamura, M.10
Tamura, M.11
Okumura, K.12
-
34
-
-
8644251442
-
Fidarestat Clinical Pharmacology Study Group. Erythrocytic sorbitol contents in diabetic patients correlate with blood aldose reductase protein contents and plasma glucose levels, and are normalized by the potent aldose reductase inhibitor fidarestat (SNK-860)
-
Asano T, Saito Y, Kawakami M, Yamada N, Sekino H, Hasegawa S; Fidarestat Clinical Pharmacology Study Group. Erythrocytic sorbitol contents in diabetic patients correlate with blood aldose reductase protein contents and plasma glucose levels, and are normalized by the potent aldose reductase inhibitor fidarestat (SNK-860). J Diabetes Complications 2004;18:336-342
-
(2004)
J Diabetes Complications
, vol.18
, pp. 336-342
-
-
Asano, T.1
Saito, Y.2
Kawakami, M.3
Yamada, N.4
Sekino, H.5
Hasegawa, S.6
-
35
-
-
0036436579
-
Sorbitol dehydrogenase overexpression potentiates glucose toxicity to cultured retinal pericytes
-
Amano S, Yamagishi S, Kato N, Inagaki Y, Okamoto T, Makino M, Taniko K, Hirooka H, Jomori T, Takeuchi M. Sorbitol dehydrogenase overexpression potentiates glucose toxicity to cultured retinal pericytes. Biochem Biophys Res Commun 2002;299:183-188
-
(2002)
Biochem Biophys Res Commun
, vol.299
, pp. 183-188
-
-
Amano, S.1
Yamagishi, S.2
Kato, N.3
Inagaki, Y.4
Okamoto, T.5
Makino, M.6
Taniko, K.7
Hirooka, H.8
Jomori, T.9
Takeuchi, M.10
-
36
-
-
0142138124
-
Long-term treatment with fidarestat suppresses the development of diabetic retinopathy in STZ-induced diabetic rats
-
Kato N, Yashima S, Suzuki T, Nakayama Y, Jomori T. Long-term treatment with fidarestat suppresses the development of diabetic retinopathy in STZ-induced diabetic rats. J Diabetes Complications 2003;17:374-379
-
(2003)
J Diabetes Complications
, vol.17
, pp. 374-379
-
-
Kato, N.1
Yashima, S.2
Suzuki, T.3
Nakayama, Y.4
Jomori, T.5
-
37
-
-
0033546655
-
Effect of aldose reductase inhibition on nerve conduction and morphometry in diabetic neuropathy. Zenarestat Study Group
-
Greene DA, Arezzo JC, Brown MB. Effect of aldose reductase inhibition on nerve conduction and morphometry in diabetic neuropathy. Zenarestat Study Group. Neurology 1999;53:580-591
-
(1999)
Neurology
, vol.53
, pp. 580-591
-
-
Greene, D.A.1
Arezzo, J.C.2
Brown, M.B.3
-
38
-
-
7644241006
-
Interaction between the polyol pathway and non-enzymatic glycation on aortic smooth muscle cell migration and monocyte adhesion
-
Dan Q, Wong R, Chung SK, Chung SS, Lam KS. Interaction between the polyol pathway and non-enzymatic glycation on aortic smooth muscle cell migration and monocyte adhesion. Life Sci 2004;76:445-459
-
(2004)
Life Sci
, vol.76
, pp. 445-459
-
-
Dan, Q.1
Wong, R.2
Chung, S.K.3
Chung, S.S.4
Lam, K.S.5
-
39
-
-
2342443119
-
Pharmacological prevention of diabetic cataract
-
Kyselova Z, Stefek M, Bauer V. Pharmacological prevention of diabetic cataract. J Diab Comp 2004;18:129-140
-
(2004)
J Diab Comp
, vol.18
, pp. 129-140
-
-
Kyselova, Z.1
Stefek, M.2
Bauer, V.3
-
40
-
-
0037047696
-
Aldose reductase is an obligatory mediator of the late phase of ischemic preconditioning
-
Shinmura K, Bolli R, Liu SQ, Tang XL, Kodani E, Xuan YT, Srivastava S, Bhatnagar A. Aldose reductase is an obligatory mediator of the late phase of ischemic preconditioning. Circ Res 2002;91:240-246
-
(2002)
Circ Res
, vol.91
, pp. 240-246
-
-
Shinmura, K.1
Bolli, R.2
Liu, S.Q.3
Tang, X.L.4
Kodani, E.5
Xuan, Y.T.6
Srivastava, S.7
Bhatnagar, A.8
-
41
-
-
0141886343
-
Aldose reductase: A novel target for cardioprotective interventions
-
Ramasamy R. Aldose reductase: a novel target for cardioprotective interventions. Curr Drug Targets 2003;4:625-632
-
(2003)
Curr Drug Targets
, vol.4
, pp. 625-632
-
-
Ramasamy, R.1
-
42
-
-
0642272495
-
Sorbitol dehydrogenase: A novel target for adjunctive protection of ischemic myocardium
-
Hwang YC, Bakr S, Ellery CA, Oates PJ, Ramasamy R. Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium. FASEB J 2003;17:2331-3
-
(2003)
FASEB J
, vol.17
, pp. 2331-2333
-
-
Hwang, Y.C.1
Bakr, S.2
Ellery, C.A.3
Oates, P.J.4
Ramasamy, R.5
-
43
-
-
21544463410
-
Aldose reductase in diabetic microvascular complications
-
Chung SS, Chung SK. Aldose reductase in diabetic microvascular complications. Curr Drug Targets 2005;6:475-486
-
(2005)
Curr Drug Targets
, vol.6
, pp. 475-486
-
-
Chung, S.S.1
Chung, S.K.2
-
44
-
-
4043145689
-
Protein glycation: A firm link to endothelial cell dysfunction
-
Wautier JL, Schmidt AM. Protein glycation: a firm link to endothelial cell dysfunction. Circ Res 2004;95:233-238
-
(2004)
Circ Res
, vol.95
, pp. 233-238
-
-
Wautier, J.L.1
Schmidt, A.M.2
-
45
-
-
0034659178
-
Glycoxidation and lipoxidation in atherogenesis
-
Baynes JW, Thorpe SR. Glycoxidation and lipoxidation in atherogenesis. Free Radic Biol Med 2000;23:1708-1716
-
(2000)
Free Radic Biol Med
, vol.23
, pp. 1708-1716
-
-
Baynes, J.W.1
Thorpe, S.R.2
-
46
-
-
0036167208
-
Diabetes and advanced glycation endproducts
-
Vlassara H, Palace MR. Diabetes and advanced glycation endproducts. J Intern Med 2002;251:87-101
-
(2002)
J Intern Med
, vol.251
, pp. 87-101
-
-
Vlassara, H.1
Palace, M.R.2
-
47
-
-
0033028542
-
Differential accumulation of advanced glycation end products in the course of diabetic retinopathy
-
Hammes HP, Alt A, Niwa T, Clausen JT, Bretzel RG, Brownlee M, Schleicher ED. Differential accumulation of advanced glycation end products in the course of diabetic retinopathy. Diabetologia 1999;42:728-736
-
(1999)
Diabetologia
, vol.42
, pp. 728-736
-
-
Hammes, H.P.1
Alt, A.2
Niwa, T.3
Clausen, J.T.4
Bretzel, R.G.5
Brownlee, M.6
Schleicher, E.D.7
-
48
-
-
0033510738
-
Advanced glycation end products in children and adolescents with diabetes: Relation to glycemic control and early microvascular complications
-
Chiarelli F, de Martino M, Mezzetti A, Catino M, Morgese G, Cuccurullo F, Verrotti A. Advanced glycation end products in children and adolescents with diabetes: relation to glycemic control and early microvascular complications. J Pediatr 1999;134:486-491
-
(1999)
J Pediatr
, vol.134
, pp. 486-491
-
-
Chiarelli, F.1
de Martino, M.2
Mezzetti, A.3
Catino, M.4
Morgese, G.5
Cuccurullo, F.6
Verrotti, A.7
-
49
-
-
0035668462
-
The AGE-receptor in the pathogenesis of diabetic complications
-
Vlassara H. The AGE-receptor in the pathogenesis of diabetic complications. Diabetes Metab Rev 2001;17:436-443
-
(2001)
Diabetes Metab Rev
, vol.17
, pp. 436-443
-
-
Vlassara, H.1
-
50
-
-
1542284166
-
Advanced glycation endproducts: Implications for accelerated atherosclerosis in diabetes
-
Basta G, Del Turco S, De Caterina R. Advanced glycation endproducts: implications for accelerated atherosclerosis in diabetes. Recenti Prog Med 2004;95:67-80
-
(2004)
Recenti Prog Med
, vol.95
, pp. 67-80
-
-
Basta, G.1
Del Turco, S.2
De Caterina, R.3
-
51
-
-
23644444151
-
Insulin resistance and type 2 diabetes in high-fat-fed mice are linked to high glycotoxin intake
-
Sandu O, Song K, Cai W, Zheng F, Uribarri J, Vlassara H, Insulin resistance and type 2 diabetes in high-fat-fed mice are linked to high glycotoxin intake. Diabetes 2005;54:2314-2319
-
(2005)
Diabetes
, vol.54
, pp. 2314-2319
-
-
Sandu, O.1
Song, K.2
Cai, W.3
Zheng, F.4
Uribarri, J.5
Vlassara, H.6
-
52
-
-
0037251741
-
Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes
-
Aronson D. Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes. J Hypertens 2003;21:3-12
-
(2003)
J Hypertens
, vol.21
, pp. 3-12
-
-
Aronson, D.1
-
53
-
-
0035143770
-
Study of Osteoporosis Features Research Group. Older women with diabetes have an increased risk of fracture: A prospective study
-
Schwartz AV, Sellmeyer DE, Ensrud KE, Cauley JA, Tabor HK, Schreiner PJ, Black DM, Cummings SR. Study of Osteoporosis Features Research Group. Older women with diabetes have an increased risk of fracture: a prospective study. J Clin Endocrinol Metab 2001;86:32-38
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 32-38
-
-
Schwartz, A.V.1
Sellmeyer, D.E.2
Ensrud, K.E.3
Cauley, J.A.4
Tabor, H.K.5
Schreiner, P.J.6
Black, D.M.7
Cummings, S.R.8
-
54
-
-
9644284528
-
Advanced Glycation End-Products Induce Connective Tissue Growth Factor-Mediated Renal Fibrosis Predominantly through Transforming Growth Factor beta-Independent Pathway
-
Zhou G, Li C, Cai L. Advanced Glycation End-Products Induce Connective Tissue Growth Factor-Mediated Renal Fibrosis Predominantly through Transforming Growth Factor beta-Independent Pathway. American Journal of Pathology 2004;165:2033-2043
-
(2004)
American Journal of Pathology
, vol.165
, pp. 2033-2043
-
-
Zhou, G.1
Li, C.2
Cai, L.3
-
55
-
-
1842639393
-
Type IV collagen is transcriptionally regulated by Smad 1 under advanced glycation end product (AGE) stimulation
-
Abe H, Matsubara T, Iehara N, Nagai K, Takahashi T, Arai H, Kita T, Doi T. Type IV collagen is transcriptionally regulated by Smad 1 under advanced glycation end product (AGE) stimulation. J Biol Chem 2004;279:14201-14206
-
(2004)
J Biol Chem
, vol.279
, pp. 14201-14206
-
-
Abe, H.1
Matsubara, T.2
Iehara, N.3
Nagai, K.4
Takahashi, T.5
Arai, H.6
Kita, T.7
Doi, T.8
-
57
-
-
1342268353
-
Advanced glycation end products activate Smad signalling via TGF-beta-dependent and independent mechanisms: Implications for diabetic renal and vascular disease
-
Li JH, Huang XR, Zhu HJ, Oldfield M, Cooper M, Truong LD, Johnson RJ, Lan HY. Advanced glycation end products activate Smad signalling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease. FASEB J 2004;18:176-178
-
(2004)
FASEB J
, vol.18
, pp. 176-178
-
-
Li, J.H.1
Huang, X.R.2
Zhu, H.J.3
Oldfield, M.4
Cooper, M.5
Truong, L.D.6
Johnson, R.J.7
Lan, H.Y.8
-
58
-
-
0036701873
-
Scavenger receptors that recognize advanced glycation end products
-
Miyazaki A, Nakayama H, Horiuchi S. Scavenger receptors that recognize advanced glycation end products. Trends Cardiovasc Med 2002;12:258-262
-
(2002)
Trends Cardiovasc Med
, vol.12
, pp. 258-262
-
-
Miyazaki, A.1
Nakayama, H.2
Horiuchi, S.3
-
59
-
-
4143087382
-
Advanced glycation endproduct (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells
-
Lu C, He JC, Cai W, Liu H, Zhu L, Vlassara H. Advanced glycation endproduct (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells. Proc Nat Acad Sci 2004;101:11767-11772
-
(2004)
Proc Nat Acad Sci
, vol.101
, pp. 11767-11772
-
-
Lu, C.1
He, J.C.2
Cai, W.3
Liu, H.4
Zhu, L.5
Vlassara, H.6
-
60
-
-
0035293890
-
Presence of diabetic complications in type 1 diabetic patients correlates with low expression of mononuclear cell AGE-receptor-1 and elevated serum AGE
-
He CJ, Koschinsky T, Buenting C, Vlassara H. Presence of diabetic complications in type 1 diabetic patients correlates with low expression of mononuclear cell AGE-receptor-1 and elevated serum AGE. Mol Med 2001;7:159-168
-
(2001)
Mol Med
, vol.7
, pp. 159-168
-
-
He, C.J.1
Koschinsky, T.2
Buenting, C.3
Vlassara, H.4
-
61
-
-
14644435056
-
Impaired retinal angiogenesis in diabetes: Role of advanced glycation end products and galectin-3
-
Stitt AW, McGoldrick C, Rice-McCaldin A, McCance DR, Glenn JV, Hsu DK, Liu FT, Thorpe SR, Gardiner TA. Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3. Diabetes 2005;54:785-794
-
(2005)
Diabetes
, vol.54
, pp. 785-794
-
-
Stitt, A.W.1
McGoldrick, C.2
Rice-McCaldin, A.3
McCance, D.R.4
Glenn, J.V.5
Hsu, D.K.6
Liu, F.T.7
Thorpe, S.R.8
Gardiner, T.A.9
-
62
-
-
23944467090
-
Development of age-dependent glomerular lesions in galectin-3 / AGEreceptor-3 knockout mice
-
Iacobini C, Oddi G, Menini S, Amadio L, Ricci C, Di Pippo C, Sorcini M, Pried F, Pugliese F, Pugliese G. Development of age-dependent glomerular lesions in galectin-3 / AGEreceptor-3 knockout mice. Am J Physiol Renal Physiol 2005;289:611-621
-
(2005)
Am J Physiol Renal Physiol
, vol.289
, pp. 611-621
-
-
Iacobini, C.1
Oddi, G.2
Menini, S.3
Amadio, L.4
Ricci, C.5
Di Pippo, C.6
Sorcini, M.7
Pried, F.8
Pugliese, F.9
Pugliese, G.10
-
63
-
-
0035918193
-
Scavenger receptor class B type I-mediated reverse cholesterol transport is inhibited by advanced glycation end products
-
Ohgami H, Nagai R, Miyazaki A, Ikemoto M, Arai H, Horiuchi S, Nakayama H. Scavenger receptor class B type I-mediated reverse cholesterol transport is inhibited by advanced glycation end products. J Biol Chem 2001;276:13348-13355
-
(2001)
J Biol Chem
, vol.276
, pp. 13348-13355
-
-
Ohgami, H.1
Nagai, R.2
Miyazaki, A.3
Ikemoto, M.4
Arai, H.5
Horiuchi, S.6
Nakayama, H.7
-
64
-
-
27744453362
-
Understanding RAGE, the receptor for advanced glycation end products
-
Bierhaus A, Humpert PM, Morcos M, Wendt T, Chavakis T, Arnold B, Stern DM, Nawroth PP. Understanding RAGE, the receptor for advanced glycation end products. J Mol Med 2005;83:876-886
-
(2005)
J Mol Med
, vol.83
, pp. 876-886
-
-
Bierhaus, A.1
Humpert, P.M.2
Morcos, M.3
Wendt, T.4
Chavakis, T.5
Arnold, B.6
Stern, D.M.7
Nawroth, P.P.8
-
65
-
-
17144430517
-
Roles of the receptor for advanced glycation endproducts in diabetes-induced vascular injury
-
Yonekura H, Yamamoto Y, Sakurai S, Watanabe T, Yamamoto H. Roles of the receptor for advanced glycation endproducts in diabetes-induced vascular injury. J Pharmacol Sci 2005;97:305-311
-
(2005)
J Pharmacol Sci
, vol.97
, pp. 305-311
-
-
Yonekura, H.1
Yamamoto, Y.2
Sakurai, S.3
Watanabe, T.4
Yamamoto, H.5
-
66
-
-
11144324314
-
Advanced glycation endproducts-role in pathology of diabetic complications
-
Ahmed N. Advanced glycation endproducts-role in pathology of diabetic complications. Diabetes Research and Clinical Practice 2005;67:3-21
-
(2005)
Diabetes Research and Clinical Practice
, vol.67
, pp. 3-21
-
-
Ahmed, N.1
-
67
-
-
23944491481
-
Bridging advanced glycation end product, receptor for advanced glycation end product and nitric oxide with hormonal replacement/estrogen therapy in healthy versus diabetic postmenopausal women: A perspective
-
Mukhopadhyay S, Mukherjee TK. Bridging advanced glycation end product, receptor for advanced glycation end product and nitric oxide with hormonal replacement/estrogen therapy in healthy versus diabetic postmenopausal women: A perspective. Biochim Biophys Acta 2005;1745:145-155
-
(2005)
Biochim Biophys Acta
, vol.1745
, pp. 145-155
-
-
Mukhopadhyay, S.1
Mukherjee, T.K.2
-
68
-
-
26444478269
-
Advanced glycation end products and RAGE: A common thread in aging, diabetes, neurodegeneration, and inflammation
-
Ramasamy R, Vannucci SJ, Yan SS, Herold K, Yan SF, Schmidt AM. Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation. Glycobiology 2005;15:16-28
-
(2005)
Glycobiology
, vol.15
, pp. 16-28
-
-
Ramasamy, R.1
Vannucci, S.J.2
Yan, S.S.3
Herold, K.4
Yan, S.F.5
Schmidt, A.M.6
-
69
-
-
85047694774
-
Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily
-
Bierhaus A, Haslbeck KM, Humpert PM, Liliensiek B, Dehmer T, Morcos M, Sayed AA, Andrassy M, Schiekofer S, Schneider JG, Schulz JB, Heuss D, Neundorfer B, Dierl S, Huber J, Tritschler H, Schmidt AM, Schwaninger M, Haering HU, Schleicher E, Kasper M, Stern DM, Arnold B, Nawroth PP. Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. J Clin Invest 2004;114:1741-1751
-
(2004)
J Clin Invest
, vol.114
, pp. 1741-1751
-
-
Bierhaus, A.1
Haslbeck, K.M.2
Humpert, P.M.3
Liliensiek, B.4
Dehmer, T.5
Morcos, M.6
Sayed, A.A.7
Andrassy, M.8
Schiekofer, S.9
Schneider, J.G.10
Schulz, J.B.11
Heuss, D.12
Neundorfer, B.13
Dierl, S.14
Huber, J.15
Tritschler, H.16
Schmidt, A.M.17
Schwaninger, M.18
Haering, H.U.19
Schleicher, E.20
Kasper, M.21
Stern, D.M.22
Arnold, B.23
Nawroth, P.P.24
more..
-
70
-
-
24644508501
-
The RAGE Axis in Early Diabetic Retinopathy
-
Barile GR, Pachydaki SI, Tari SR, Lee SE, Donmoyer CM, Ma W, Rong LL, Buciarelli LG, Wendt T, Horig H, Hudson BI, Qu W, Weinberg AD, Yan SF, Schmidt AM. The RAGE Axis in Early Diabetic Retinopathy. Invest Ophthalmol Vis Sci 2005;46:2916-2924
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 2916-2924
-
-
Barile, G.R.1
Pachydaki, S.I.2
Tari, S.R.3
Lee, S.E.4
Donmoyer, C.M.5
Ma, W.6
Rong, L.L.7
Buciarelli, L.G.8
Wendt, T.9
Horig, H.10
Hudson, B.I.11
Qu, W.12
Weinberg, A.D.13
Yan, S.F.14
Schmidt, A.M.15
-
71
-
-
0037377697
-
RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy
-
Wendt TM, Tanji N, Guo J, Kislinger TR, Qu W, Lu Y, Bucciarelli LG, Rong LL, Moser B, Markowitz GS, Stein G, Bierhaus A, Liliensiek B, Arnold B, Nawroth PP, Stern DM, D'Agati VD, Schmidt AM. RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy. Am J Pathol 2003;162:1123-1137
-
(2003)
Am J Pathol
, vol.162
, pp. 1123-1137
-
-
Wendt, T.M.1
Tanji, N.2
Guo, J.3
Kislinger, T.R.4
Qu, W.5
Lu, Y.6
Bucciarelli, L.G.7
Rong, L.L.8
Moser, B.9
Markowitz, G.S.10
Stein, G.11
Bierhaus, A.12
Liliensiek, B.13
Arnold, B.14
Nawroth, P.P.15
Stern, D.M.16
D'Agati, V.D.17
Schmidt, A.M.18
-
72
-
-
0034947508
-
Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice
-
Yamamoto Y, Kato I, Doi T, Yonekura H, Ohashi S, Takeuchi M, Watanabe T, Yamagishi S, Sakurai S, Takasawa S, Okamoto H, Yamamoto H. Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice. J Clin Invest 2001;108:261-268
-
(2001)
J Clin Invest
, vol.108
, pp. 261-268
-
-
Yamamoto, Y.1
Kato, I.2
Doi, T.3
Yonekura, H.4
Ohashi, S.5
Takeuchi, M.6
Watanabe, T.7
Yamagishi, S.8
Sakurai, S.9
Takasawa, S.10
Okamoto, H.11
Yamamoto, H.12
-
73
-
-
9444266461
-
RAGE-and TGF-beta receptor-mediated signals converge on STAT5 and p21waf to control cell-cycle progression of mesangial cells: A possible role in the development and progression of diabetic nephropathy
-
Brizzi MF, Dentelli P, Rosso A, Calvi C, Gambino R, Cassader M, Salvidio G, Deferrari G, Camussi G, Pegoraro L, Pagano G, Cavallo-Perin P. RAGE-and TGF-beta receptor-mediated signals converge on STAT5 and p21waf to control cell-cycle progression of mesangial cells: a possible role in the development and progression of diabetic nephropathy. FASEB J 2004;18:1249-1251
-
(2004)
FASEB J
, vol.18
, pp. 1249-1251
-
-
Brizzi, M.F.1
Dentelli, P.2
Rosso, A.3
Calvi, C.4
Gambino, R.5
Cassader, M.6
Salvidio, G.7
Deferrari, G.8
Camussi, G.9
Pegoraro, L.10
Pagano, G.11
Cavallo-Perin, P.12
-
74
-
-
16844382710
-
Advanced glycation end products enhance expression of pro-apoptotic genes and stimulate fibroblast apoptosis through cytoplasmic and mitochondrial pathways
-
Alikhani Z, Alikhani M, Boyd CM, Nagao K, Trackman PC, Graves DT. Advanced glycation end products enhance expression of pro-apoptotic genes and stimulate fibroblast apoptosis through cytoplasmic and mitochondrial pathways. J Biol Chem 2005;280:12087-12095
-
(2005)
J Biol Chem
, vol.280
, pp. 12087-12095
-
-
Alikhani, Z.1
Alikhani, M.2
Boyd, C.M.3
Nagao, K.4
Trackman, P.C.5
Graves, D.T.6
-
75
-
-
1542721873
-
Advanced glycation endproduct crosslinking in the cardiovascular system: Potential therapeutic target for cardiovascular disease
-
Zieman SJ, Kass DA. Advanced glycation endproduct crosslinking in the cardiovascular system: potential therapeutic target for cardiovascular disease. Drugs 2004;64:459-470
-
(2004)
Drugs
, vol.64
, pp. 459-470
-
-
Zieman, S.J.1
Kass, D.A.2
-
77
-
-
22344442393
-
Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation
-
Rosca MG, Mustata TG, Kinter MT, Ozdemir AM, Kern TS, Szweda LI, Brownlee M, Monnier VM, Weiss MF. Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation. Am J Physiol Renal Physiol 2005;289:F420-F430
-
(2005)
Am J Physiol Renal Physiol
, vol.289
-
-
Rosca, M.G.1
Mustata, T.G.2
Kinter, M.T.3
Ozdemir, A.M.4
Kern, T.S.5
Szweda, L.I.6
Brownlee, M.7
Monnier, V.M.8
Weiss, M.F.9
-
78
-
-
10744223527
-
Investigator Group. Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy
-
Bolton WK, Cattran DC, Williams ME, Adler SG, Appel GB, Cartwright K, Foiles PG, Freedman BI, Raskin P, Ratner RE, Spinowitz BS, Whittier FC, Wuerth JP ACTION I Investigator Group. Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy. Am J Nephrol 2004;24:32-4079.
-
(2004)
Am J Nephrol
, vol.24
, pp. 32-4079
-
-
Bolton, W.K.1
Cattran, D.C.2
Williams, M.E.3
Adler, S.G.4
Appel, G.B.5
Cartwright, K.6
Foiles, P.G.7
Freedman, B.I.8
Raskin, P.9
Ratner, R.E.10
Spinowitz, B.S.11
Whittier, F.C.12
Wuerth, J.A.I.13
-
79
-
-
0037379212
-
Glycated collagen cross-linking alters cardiac mechanics in volume-overload hypertrophy
-
Herrmann KL, McCulloch AD, Omens JH. Glycated collagen cross-linking alters cardiac mechanics in volume-overload hypertrophy. Am J Physiol Heart Circ Physiol 2003;284:H1277-H1284
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
-
-
Herrmann, K.L.1
McCulloch, A.D.2
Omens, J.H.3
-
80
-
-
0038152985
-
Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice
-
Tamarat R, Silvestre JS, Huijberts M, Benessiano J, Ebrahimian TG, Duriez M, Wautier MP, Wautier JL, Levy BI. Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice. Proc Natl Acad Sci 2003;100:8555-8560
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 8555-8560
-
-
Tamarat, R.1
Silvestre, J.S.2
Huijberts, M.3
Benessiano, J.4
Ebrahimian, T.G.5
Duriez, M.6
Wautier, M.P.7
Wautier, J.L.8
Levy, B.I.9
-
81
-
-
0036183727
-
Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocindiabetic rat
-
Degenhardt TP, Alderson NL, Arrington DD, Beattie RJ, Basgen JM, Steffes MW, Thorpe SR, Baynes JW. Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocindiabetic rat. Kidney Int 2002;61:939-950
-
(2002)
Kidney Int
, vol.61
, pp. 939-950
-
-
Degenhardt, T.P.1
Alderson, N.L.2
Arrington, D.D.3
Beattie, R.J.4
Basgen, J.M.5
Steffes, M.W.6
Thorpe, S.R.7
Baynes, J.W.8
-
82
-
-
0036723821
-
-
Stitt A, Gardiner TA, Alderson NL, Canning P, Frizzetl N, Duffy N, Boyle C, Januszewski AS, Chachich M, Baynes JW, Thorpe SR. The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes 2002;51:2826-2832 Erratum in: Diabetes 2003;52:223 Anderson NLcorrected to Alderson NL
-
Stitt A, Gardiner TA, Alderson NL, Canning P, Frizzetl N, Duffy N, Boyle C, Januszewski AS, Chachich M, Baynes JW, Thorpe SR. The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes 2002;51:2826-2832 Erratum in: Diabetes 2003;52:223 Anderson NLcorrected to Alderson NL
-
-
-
-
83
-
-
0141483457
-
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes
-
Forbes JM, Thallas V, Thomas MC, Founds HW, Burns WC, Jerums G, Cooper ME. The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes. FASEB J 2003;17:1762-1764
-
(2003)
FASEB J
, vol.17
, pp. 1762-1764
-
-
Forbes, J.M.1
Thallas, V.2
Thomas, M.C.3
Founds, H.W.4
Burns, W.C.5
Jerums, G.6
Cooper, M.E.7
-
84
-
-
10644246127
-
Advanced glycation end-product cross-link breakers. A novel approach to cardiovascular pathologies related to the aging process
-
Bakris GL, Bank AJ, Kass DA, Neutel JM, Preston RA, Oparil S. Advanced glycation end-product cross-link breakers. A novel approach to cardiovascular pathologies related to the aging process. Am J Hypertens 2004;17:23S-30S
-
(2004)
Am J Hypertens
, vol.17
-
-
Bakris, G.L.1
Bank, A.J.2
Kass, D.A.3
Neutel, J.M.4
Preston, R.A.5
Oparil, S.6
-
85
-
-
33645219720
-
Renal effects of a neutralising RAGE-antibody in long-term streptozotocin- diabetic mice
-
Jensen LJ, Denner L, Schrijvers BF, Tilton RG, Rasch R, Flyvbjerg A. Renal effects of a neutralising RAGE-antibody in long-term streptozotocin- diabetic mice. J Endocrinol. 2006;188:493-501
-
(2006)
J Endocrinol
, vol.188
, pp. 493-501
-
-
Jensen, L.J.1
Denner, L.2
Schrijvers, B.F.3
Tilton, R.G.4
Rasch, R.5
Flyvbjerg, A.6
-
86
-
-
0032104245
-
The extended protein kinase C superfamily
-
Mellor H, Parker PJ. The extended protein kinase C superfamily. Biochem J 1998;332:281-292
-
(1998)
Biochem J
, vol.332
, pp. 281-292
-
-
Mellor, H.1
Parker, P.J.2
-
87
-
-
0034852862
-
Protein kinase C activation: Isozyme-specific effects on metabolism and cardiovascular complications in diabetes
-
Idris I, Gray S, Donnelly R. Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes. Diabetologia 2001;44:659-673
-
(2001)
Diabetologia
, vol.44
, pp. 659-673
-
-
Idris, I.1
Gray, S.2
Donnelly, R.3
-
88
-
-
14644419622
-
Proatherosclerotic mechanisms involving protein kinase C in diabetes and insulin resistance
-
Rask-Madsen C, King GL. Proatherosclerotic mechanisms involving protein kinase C in diabetes and insulin resistance. Arterioscler Thromb Vasc Biol 2005;25:487-496
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 487-496
-
-
Rask-Madsen, C.1
King, G.L.2
-
89
-
-
0031860340
-
Protein kinase C activation and the development of diabetic complications
-
Koya D, King G. Protein kinase C activation and the development of diabetic complications. Diabetes 1998;47:859-866
-
(1998)
Diabetes
, vol.47
, pp. 859-866
-
-
Koya, D.1
King, G.2
-
90
-
-
0034750946
-
Molecular biology of protein kinase C signalling in cardiac myocytes
-
Malhotra A, Kang BP, Opawumi D, Belizaire W, Meggs LG. Molecular biology of protein kinase C signalling in cardiac myocytes. Mol Cell Biochem 2001;225:97-107
-
(2001)
Mol Cell Biochem
, vol.225
, pp. 97-107
-
-
Malhotra, A.1
Kang, B.P.2
Opawumi, D.3
Belizaire, W.4
Meggs, L.G.5
-
91
-
-
0033765672
-
High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells
-
Inoguchi T, Li P, Umeda F, Yu HY, Kakimoto M, Imamura M, Aoki T, Etoh T, Hashimoto T, Naruse M, Sano H, Utsumi H, Nawata H. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes 2000;49:1939-1945
-
(2000)
Diabetes
, vol.49
, pp. 1939-1945
-
-
Inoguchi, T.1
Li, P.2
Umeda, F.3
Yu, H.Y.4
Kakimoto, M.5
Imamura, M.6
Aoki, T.7
Etoh, T.8
Hashimoto, T.9
Naruse, M.10
Sano, H.11
Utsumi, H.12
Nawata, H.13
-
92
-
-
0035793616
-
Mechanisms underlying endothelial dysfunction in diabetes mellitus
-
Hink U, Li H, Mollnau H, Oelze M, Matheis E, Hartmann M, Skatchkov M, Thaiss F, Stahl RA, Warnholtz A, Meinertz T, Griendling K, Harrison DG, Forstermann U, Munzel T. Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res 2001;88:E14-E22
-
(2001)
Circ Res
, vol.88
-
-
Hink, U.1
Li, H.2
Mollnau, H.3
Oelze, M.4
Matheis, E.5
Hartmann, M.6
Skatchkov, M.7
Thaiss, F.8
Stahl, R.A.9
Warnholtz, A.10
Meinertz, T.11
Griendling, K.12
Harrison, D.G.13
Forstermann, U.14
Munzel, T.15
-
93
-
-
0037465359
-
High glucose causes upregulation of cydooxygenase-2 and alters prostanoid profile in human endothelial cells: Role of protein kinase C and reactive oxygen species
-
Cosentino F, Eto M, De Paolis P, van der Loo B, Bachschmid M, Ullrich V, Kouroedov A, Delli Gatti C, Joch H, Volpe M, Luscher TF. High glucose causes upregulation of cydooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species. Circulation 2003;107:1017-1023
-
(2003)
Circulation
, vol.107
, pp. 1017-1023
-
-
Cosentino, F.1
Eto, M.2
De Paolis, P.3
van der Loo, B.4
Bachschmid, M.5
Ullrich, V.6
Kouroedov, A.7
Delli Gatti, C.8
Joch, H.9
Volpe, M.10
Luscher, T.F.11
-
94
-
-
0141730235
-
-
Luscher TF, Creager MA, Beckman JA, Cosentino F. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy. Part II. Circulation 2003;108:1655-1661
-
Luscher TF, Creager MA, Beckman JA, Cosentino F. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy. Part II. Circulation 2003;108:1655-1661
-
-
-
-
95
-
-
0033949316
-
Induction of endothelin-1 expression by glucose: An effect of protein kinase C activation
-
Park JY, Takahara N, Gabriele A, Chou E, Naruse K, Suzuma K, Yamauchi T, Ha SW, Meier M, Rhodes CJ, King GL. Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation. Diabetes 2000;49:1239-1248
-
(2000)
Diabetes
, vol.49
, pp. 1239-1248
-
-
Park, J.Y.1
Takahara, N.2
Gabriele, A.3
Chou, E.4
Naruse, K.5
Suzuma, K.6
Yamauchi, T.7
Ha, S.W.8
Meier, M.9
Rhodes, C.J.10
King, G.L.11
-
96
-
-
0037154156
-
Characterization of protein kinase C β isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization
-
Suzuma K, Takahara N, Suzuma I, Isshiki K, Ueki K, Leitges M, Aiello LP, King GL. Characterization of protein kinase C β isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization. Proc Natl Acad Sci 2002;99:721-726
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 721-726
-
-
Suzuma, K.1
Takahara, N.2
Suzuma, I.3
Isshiki, K.4
Ueki, K.5
Leitges, M.6
Aiello, L.P.7
King, G.L.8
-
97
-
-
0033797262
-
Diabetes mellitus increases endothelin-1 gene transcription in rat kidney
-
Hargrove GM, Dufresne J, Whiteside CI, Muruve DA, Wong NCW. Diabetes mellitus increases endothelin-1 gene transcription in rat kidney. Kidney Int 2000;58:534-1545
-
(2000)
Kidney Int
, vol.58
, pp. 534-1545
-
-
Hargrove, G.M.1
Dufresne, J.2
Whiteside, C.I.3
Muruve, D.A.4
Wong, N.C.W.5
-
98
-
-
0037408533
-
Overview of glucose signaling in mesangial cells in diabetic nephropathy
-
Haneda M, Koya D, Isono M, Kikkawa R. Overview of glucose signaling in mesangial cells in diabetic nephropathy. J Am Soc Nephrol 2003;14:1374-1382
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1374-1382
-
-
Haneda, M.1
Koya, D.2
Isono, M.3
Kikkawa, R.4
-
99
-
-
0035489474
-
High Glucose-Enhanced Mesangial Cell Extracellular Signal-Regulated Protein Kinase Activation and 1(IV) Collagen Expression in Response to Endothelin-1 Role of Specific Protein Kinase C Isozymes
-
Hua H, Goldberg HJ, Fantus IG, Whiteside CI. High Glucose-Enhanced Mesangial Cell Extracellular Signal-Regulated Protein Kinase Activation and 1(IV) Collagen Expression in Response to Endothelin-1 Role of Specific Protein Kinase C Isozymes, Diabetes 2001;50:2376-2383
-
(2001)
Diabetes
, vol.50
, pp. 2376-2383
-
-
Hua, H.1
Goldberg, H.J.2
Fantus, I.G.3
Whiteside, C.I.4
-
100
-
-
0035211205
-
Neuropathy in diabetic mice overexpressing human aldose reductase and effects of aldose reductase inhibitor
-
Yagihashi S, Yamagishi SI, Wada Ri R, Baba M, Hohman TC, Yabe-Nishimura C, Kokai Y. Neuropathy in diabetic mice overexpressing human aldose reductase and effects of aldose reductase inhibitor. Brain 2001;124:2448-2458
-
(2001)
Brain
, vol.124
, pp. 2448-2458
-
-
Yagihashi, S.1
Yamagishi, S.I.2
Wada, R.R.3
Baba, M.4
Hohman, T.C.5
Yabe-Nishimura, C.6
Kokai, Y.7
-
101
-
-
12344252770
-
The acute effects of glycemic control on nerve conduction in human diabetics
-
Kikkawa Y, Kuwabara S, Misawa S, Tamura N, Kitano Y, Ogawara K, Hattori T. The acute effects of glycemic control on nerve conduction in human diabetics. Clin Neurophysiol 2005;116:270-274
-
(2005)
Clin Neurophysiol
, vol.116
, pp. 270-274
-
-
Kikkawa, Y.1
Kuwabara, S.2
Misawa, S.3
Tamura, N.4
Kitano, Y.5
Ogawara, K.6
Hattori, T.7
-
102
-
-
0037359304
-
Polyol pathway and protein kinase C activity of rat Schwannoma cells
-
Kamiya H, Nakamura J, Hamada Y, Nakashima E, Naruse K, Kato K, Yasuda Y, Hotta N. Polyol pathway and protein kinase C activity of rat Schwannoma cells. Diabetes Metab Res Rev 2003;19:131-139
-
(2003)
Diabetes Metab Res Rev
, vol.19
, pp. 131-139
-
-
Kamiya, H.1
Nakamura, J.2
Hamada, Y.3
Nakashima, E.4
Naruse, K.5
Kato, K.6
Yasuda, Y.7
Hotta, N.8
-
103
-
-
0141884368
-
Differential influence of increased polyol pathway on protein kinase C expressions between endoneurial and epineurial tissues in diabetic mice
-
Yamagishi S, Uehara K, Otsuki S, Yagihashi S. Differential influence of increased polyol pathway on protein kinase C expressions between endoneurial and epineurial tissues in diabetic mice. J Neurochem 2003;87:497-507
-
(2003)
J Neurochem
, vol.87
, pp. 497-507
-
-
Yamagishi, S.1
Uehara, K.2
Otsuki, S.3
Yagihashi, S.4
-
104
-
-
0033830338
-
Protein kinase C isozymes and the regulation of diverse cell responses
-
Dempsey EC, Newton AC, Mochly-Rosen D, Fields AP, Reyland ME, Insel PA, Messing RO. Protein kinase C isozymes and the regulation of diverse cell responses. Am J Physiol Lung Cell Mol Physiol 2000;279:L429-L438
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.279
-
-
Dempsey, E.C.1
Newton, A.C.2
Mochly-Rosen, D.3
Fields, A.P.4
Reyland, M.E.5
Insel, P.A.6
Messing, R.O.7
-
105
-
-
0037072740
-
The hexosamine pathway regulates the plasminogen activator inhibitor-1 gene promoter and Sp1 transcriptional activation through protein kinase C-beta I and delta
-
Goldberg HJ, Whiteside CI, Fantus IG. The hexosamine pathway regulates the plasminogen activator inhibitor-1 gene promoter and Sp1 transcriptional activation through protein kinase C-beta I and delta. J Biol Chem 2002;277:33833-33841
-
(2002)
J Biol Chem
, vol.277
, pp. 33833-33841
-
-
Goldberg, H.J.1
Whiteside, C.I.2
Fantus, I.G.3
-
106
-
-
33644802450
-
Can Protein Kinase C β-Selective Inhibitor, Ruboxistaurin, Stop Vascular Complications in Diabetic Patients?
-
He Z, King GL. Can Protein Kinase C β-Selective Inhibitor, Ruboxistaurin, Stop Vascular Complications in Diabetic Patients? Diabetes Care 2005;28:2803-2805
-
(2005)
Diabetes Care
, vol.28
, pp. 2803-2805
-
-
He, Z.1
King, G.L.2
-
107
-
-
0034053336
-
Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes
-
Koya D, Haneda M, Nakagawa H, Isshiki K, Sato H, Maeda S, Sugimoto T, Yasuda H, Kashiwagi A, Ways DK, King GL, Kikkawa R. Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes. FASEB J 2000;14:439-447
-
(2000)
FASEB J
, vol.14
, pp. 439-447
-
-
Koya, D.1
Haneda, M.2
Nakagawa, H.3
Isshiki, K.4
Sato, H.5
Maeda, S.6
Sugimoto, T.7
Yasuda, H.8
Kashiwagi, A.9
Ways, D.K.10
King, G.L.11
Kikkawa, R.12
-
108
-
-
33644842187
-
Inhibition of PKC beta by oral administration of ruboxistaurin is well tolerated and ameliorates diabetes-induced retinal hemodynamic abnormalities in patients
-
Aiello LP, Clermont A, Arora V, Davis MD, Sheetz MJ, Bursell SE. Inhibition of PKC beta by oral administration of ruboxistaurin is well tolerated and ameliorates diabetes-induced retinal hemodynamic abnormalities in patients. Invest Ophthalmol Vis Sci 2006;47:86-92
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 86-92
-
-
Aiello, L.P.1
Clermont, A.2
Arora, V.3
Davis, M.D.4
Sheetz, M.J.5
Bursell, S.E.6
-
110
-
-
5744224686
-
Therapeutic potential of natural compounds that regulate the activity of protein kinase C
-
Carter CA, Kane CJ. Therapeutic potential of natural compounds that regulate the activity of protein kinase C. Curr Med Chem 2004;11:2883-2902
-
(2004)
Curr Med Chem
, vol.11
, pp. 2883-2902
-
-
Carter, C.A.1
Kane, C.J.2
-
111
-
-
0037013983
-
Glucosamine-6-phosphate synthase-the multi-facets enzyme
-
Milewski S. Glucosamine-6-phosphate synthase-the multi-facets enzyme. Biochim Biophys Acta 2002;1597:173-192
-
(2002)
Biochim Biophys Acta
, vol.1597
, pp. 173-192
-
-
Milewski, S.1
-
112
-
-
5444269110
-
The Cellular Fate of Glucose and Its Relevance in Type 2 Diabetes
-
Bouche C, Serdy S, Kahn CR, Goldfine AB. The Cellular Fate of Glucose and Its Relevance in Type 2 Diabetes, Endocr Rev 2004;25:807-830
-
(2004)
Endocr Rev
, vol.25
, pp. 807-830
-
-
Bouche, C.1
Serdy, S.2
Kahn, C.R.3
Goldfine, A.B.4
-
113
-
-
0038574568
-
Glutamine: Fructose-6-phosphate aminotransferase enzyme activity is necessary for the induction of TGF-beta1 and fibronectin expression in mesangial cells
-
Weigert C, Friess U, Brodbeck K, Haring HU, Schleicher ED. Glutamine: fructose-6-phosphate aminotransferase enzyme activity is necessary for the induction of TGF-beta1 and fibronectin expression in mesangial cells. Diabetologia 2003;46:852-855
-
(2003)
Diabetologia
, vol.46
, pp. 852-855
-
-
Weigert, C.1
Friess, U.2
Brodbeck, K.3
Haring, H.U.4
Schleicher, E.D.5
-
114
-
-
0034710891
-
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
-
Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, Wu J, Brownlee M. Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci 2000;97:12222-12226
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 12222-12226
-
-
XL, D.1
Edelstein, D.2
Rossetti, L.3
Fantus, I.G.4
Goldberg, H.5
Ziyadeh, F.6
Wu, J.7
Brownlee, M.8
-
115
-
-
0035180299
-
Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site
-
Du XL, Edelstein D, Dimmeler S, Ju Q, Sui C, Brownlee M. Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site. J Clin Invest 2001;108:1341-1348
-
(2001)
J Clin Invest
, vol.108
, pp. 1341-1348
-
-
XL, D.1
Edelstein, D.2
Dimmeler, S.3
Ju, Q.4
Sui, C.5
Brownlee, M.6
-
116
-
-
0034083716
-
Glucosamine Activates the Plasminogen Activator Inhibitor 1 Gene Promoter Through Sp1 DNA Binding Sites in Glomerular Mesangial Cells
-
Goldberg HJ, Scholey J, Fantus IG. Glucosamine Activates the Plasminogen Activator Inhibitor 1 Gene Promoter Through Sp1 DNA Binding Sites in Glomerular Mesangial Cells. Diabetes 2000;49:863-871
-
(2000)
Diabetes
, vol.49
, pp. 863-871
-
-
Goldberg, H.J.1
Scholey, J.2
Fantus, I.G.3
-
117
-
-
1942469517
-
Upstream stimulatory factor (USF) proteins induce human TGF-beta 1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: Upregulation of USF activity by the hexosamine biosynthetic pathway
-
Weigert C, Brodbeck K, Sawadogo M, Haring HU, Schleicher ED. Upstream stimulatory factor (USF) proteins induce human TGF-beta 1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: upregulation of USF activity by the hexosamine biosynthetic pathway. J Biol Chem 2004;279:15908-15915
-
(2004)
J Biol Chem
, vol.279
, pp. 15908-15915
-
-
Weigert, C.1
Brodbeck, K.2
Sawadogo, M.3
Haring, H.U.4
Schleicher, E.D.5
-
118
-
-
0036145255
-
Hyperglycemia induces PAI-1 gene expression in adipose tissue by activation of the hexosamine biosynthetic pathway
-
Gabriely I, Yang XM, Cases JA, Ma XH, Rossetti L, Barzilai N. Hyperglycemia induces PAI-1 gene expression in adipose tissue by activation of the hexosamine biosynthetic pathway. Atherosclerosis 2002;160:115-122
-
(2002)
Atherosclerosis
, vol.160
, pp. 115-122
-
-
Gabriely, I.1
Yang, X.M.2
Cases, J.A.3
Ma, X.H.4
Rossetti, L.5
Barzilai, N.6
-
119
-
-
6344261703
-
Role of hexosamines in insulin resistance and nutrient sensing in human adipose and muscle tissue
-
Pouwels MJ, Tack CJ, Span PN, Olthaar AJ, Sweep CG, Huvers FC, Lutterman JA, Hermus AR. Role of hexosamines in insulin resistance and nutrient sensing in human adipose and muscle tissue. J Clin Endocrinol Metab 2004;89:5132-5137
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5132-5137
-
-
Pouwels, M.J.1
Tack, C.J.2
Span, P.N.3
Olthaar, A.J.4
Sweep, C.G.5
Huvers, F.C.6
Lutterman, J.A.7
Hermus, A.R.8
-
120
-
-
4143074732
-
Dynamic actions of glucose and glucosamine on hexosamine biosynthesis in isolated adipocytes: Differential effects on glucosamine 6-phosphate, UDP-N-acetylglucosamine, and ATP levels
-
Marshall S, Nadeau O, Yamasaki K. Dynamic actions of glucose and glucosamine on hexosamine biosynthesis in isolated adipocytes: differential effects on glucosamine 6-phosphate, UDP-N-acetylglucosamine, and ATP levels. J Biol Chem 2004;279:35313-35319
-
(2004)
J Biol Chem
, vol.279
, pp. 35313-35319
-
-
Marshall, S.1
Nadeau, O.2
Yamasaki, K.3
-
121
-
-
0036399745
-
The hexosamine biosynthesis pathway regulates insulin secretion via protein glycosylation in mouse islets
-
Zraika S, Dunlop M, Proietto J, Andrikopoulos S. The hexosamine biosynthesis pathway regulates insulin secretion via protein glycosylation in mouse islets. Arch Biochem Biophys 2002;405:275-279
-
(2002)
Arch Biochem Biophys
, vol.405
, pp. 275-279
-
-
Zraika, S.1
Dunlop, M.2
Proietto, J.3
Andrikopoulos, S.4
-
122
-
-
0035903192
-
Activation of the hexosamine pathway leads to deterioration of pancreatic beta-cell function through the induction of oxidative stress
-
Kaneto H, Xu G, Song KH, Suzuma K, Bonner-Weir S, Sharma A, Weir GC. Activation of the hexosamine pathway leads to deterioration of pancreatic beta-cell function through the induction of oxidative stress. J Biol Chem 2001;276:31099-310104
-
(2001)
J Biol Chem
, vol.276
, pp. 31099-310104
-
-
Kaneto, H.1
Xu, G.2
Song, K.H.3
Suzuma, K.4
Bonner-Weir, S.5
Sharma, A.6
Weir, G.C.7
-
123
-
-
0035099711
-
Glucose-induced insulin resistance of phosphatidylinositol 3′-OH kinase and AKT/PKB is mediated by the hexosamine biosynthesis pathway
-
Singh LP, Gennerette D, Simmons S, Crook ED. Glucose-induced insulin resistance of phosphatidylinositol 3′-OH kinase and AKT/PKB is mediated by the hexosamine biosynthesis pathway. J Diabetes Complications 2001;15:88-96
-
(2001)
J Diabetes Complications
, vol.15
, pp. 88-96
-
-
Singh, L.P.1
Gennerette, D.2
Simmons, S.3
Crook, E.D.4
-
124
-
-
17444381142
-
Adipocytes with increased hexosamine flux exhibit insulin resistance, increased glucose uptake, and increased synthesis and storage of lipid
-
McClain DA, Hazel M, Parker G, Cooksey RC. Adipocytes with increased hexosamine flux exhibit insulin resistance, increased glucose uptake, and increased synthesis and storage of lipid. Am J Physiol Endocrinol Metab 2005;288:E97397-E97399
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
McClain, D.A.1
Hazel, M.2
Parker, G.3
Cooksey, R.C.4
-
125
-
-
0037117511
-
Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes
-
Vosseller K, Wells L, Lane MD, Hart GW. Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes. Proc Natl Acad Sci 2002;99:5313-5318
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 5313-5318
-
-
Vosseller, K.1
Wells, L.2
Lane, M.D.3
Hart, G.W.4
-
126
-
-
0037339778
-
The response of antioxidant genes to hyperglycemia is abnormal in patients with type 1 diabetes and diabetic nephropathy
-
Hodgkinson AD, Bartlett T, Oates PJ, Millward BA, Demaine AG. The response of antioxidant genes to hyperglycemia is abnormal in patients with type 1 diabetes and diabetic nephropathy. Diabetes 2003;52:846-851
-
(2003)
Diabetes
, vol.52
, pp. 846-851
-
-
Hodgkinson, A.D.1
Bartlett, T.2
Oates, P.J.3
Millward, B.A.4
Demaine, A.G.5
-
127
-
-
0345303816
-
Oral antioxidant therapy improves endothelial function in Type 1 but not Type 2 diabetes mellitus
-
Beckman JA, Goldfine AB, Gordon MB, Garrett LA, Keaney JF Jr, Creager MA. Oral antioxidant therapy improves endothelial function in Type 1 but not Type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol 2003;285:H2392-H2398
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
-
-
Beckman, J.A.1
Goldfine, A.B.2
Gordon, M.B.3
Garrett, L.A.4
Keaney Jr, J.F.5
Creager, M.A.6
-
129
-
-
13844309278
-
Aspects of oxidative stress in children with type 1 diabetes mellitus
-
Dec;
-
Varvarovska J, Racek J, Stetina R, Sykora J, Pomahacova R, Rusavy Z, Lacigova S, Trefil L, Siala K, Stozicky F. Aspects of oxidative stress in children with type 1 diabetes mellitus. Biomed Pharmacother 2004 Dec;58:539-545
-
(2004)
Biomed Pharmacother
, vol.58
, pp. 539-545
-
-
Varvarovska, J.1
Racek, J.2
Stetina, R.3
Sykora, J.4
Pomahacova, R.5
Rusavy, Z.6
Lacigova, S.7
Trefil, L.8
Siala, K.9
Stozicky, F.10
-
130
-
-
0034764681
-
BMCP1: A mitochondrial uncoupling protein in neurons which regulates mitochondrial function and oxidant production
-
Kim-Han JS, Reichert SA, Quick KL, Dugan LL. BMCP1: a mitochondrial uncoupling protein in neurons which regulates mitochondrial function and oxidant production. J Neurochem 2001;79:658-668
-
(2001)
J Neurochem
, vol.79
, pp. 658-668
-
-
Kim-Han, J.S.1
Reichert, S.A.2
Quick, K.L.3
Dugan, L.L.4
-
131
-
-
85047691537
-
Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells
-
Du X, Matsumura T, Edelstein D, Rossetti L, Zsengeller Z, Szabo C, Brownlee M. Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J Clin Invest 2003;112:1049-1057
-
(2003)
J Clin Invest
, vol.112
, pp. 1049-1057
-
-
Du, X.1
Matsumura, T.2
Edelstein, D.3
Rossetti, L.4
Zsengeller, Z.5
Szabo, C.6
Brownlee, M.7
-
132
-
-
4444314280
-
Glycated Albumin Induces Superoxide Generation in Mesangial Cells
-
Yoo CW, Song CY, Kim BC, Hong HK, Lee HS. Glycated Albumin Induces Superoxide Generation in Mesangial Cells. Cell Physiol Biochem 2004;14:361-368
-
(2004)
Cell Physiol Biochem
, vol.14
, pp. 361-368
-
-
Yoo, C.W.1
Song, C.Y.2
Kim, B.C.3
Hong, H.K.4
Lee, H.S.5
-
133
-
-
0141755311
-
Translocation of glomerular p47phox and p67phox by protein kinase C-β activation is required for oxidative stress in diabetic nephropathy
-
Kitada M, Koya D, Sugimoto T, Isono M, Araki S, Kashiwagi A, Haneda M. Translocation of glomerular p47phox and p67phox by protein kinase C-β activation is required for oxidative stress in diabetic nephropathy. Diabetes 2003;52:2603-2614
-
(2003)
Diabetes
, vol.52
, pp. 2603-2614
-
-
Kitada, M.1
Koya, D.2
Sugimoto, T.3
Isono, M.4
Araki, S.5
Kashiwagi, A.6
Haneda, M.7
-
134
-
-
17744364508
-
Effect of NAD(P)H oxidase inhibitor in diabetic nephropathy
-
Asaba K, Tojo A, Onozato ML, Goto A, Quinn MT, Fujita T, Wilcox CS. Effect of NAD(P)H oxidase inhibitor in diabetic nephropathy. Kidney International 2005;67:1890-1898
-
(2005)
Kidney International
, vol.67
, pp. 1890-1898
-
-
Asaba, K.1
Tojo, A.2
Onozato, M.L.3
Goto, A.4
Quinn, M.T.5
Fujita, T.6
Wilcox, C.S.7
-
135
-
-
0141755317
-
Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: Potential role in diabetic nephropathy
-
Kiritoshi S, Nishikawa T, Sonoda K, Kukidome D, Senokuchi T, Matsuo T, Matsumura T, Tokunaga H, Brownlee M, Araki E. Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy. Diabetes 2003;52:2570-2577
-
(2003)
Diabetes
, vol.52
, pp. 2570-2577
-
-
Kiritoshi, S.1
Nishikawa, T.2
Sonoda, K.3
Kukidome, D.4
Senokuchi, T.5
Matsuo, T.6
Matsumura, T.7
Tokunaga, H.8
Brownlee, M.9
Araki, E.10
-
136
-
-
0036845661
-
High glucose-induced oxidative stress and mitochondrial dysfunction in neurons
-
Russell JW, Golovoy D, Vincent AM, Mahendru P, Olzmann JA, Mentzer A, Feldman EL. High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB J 2002;16:1738-1748
-
(2002)
FASEB J
, vol.16
, pp. 1738-1748
-
-
Russell, J.W.1
Golovoy, D.2
Vincent, A.M.3
Mahendru, P.4
Olzmann, J.A.5
Mentzer, A.6
Feldman, E.L.7
-
137
-
-
0344012015
-
Hyperglycemia increases mitochondrial superoxide in retina and retinal cells
-
Du Y, Miller C, Kern T. Hyperglycemia increases mitochondrial superoxide in retina and retinal cells. Free Radic Biol Med 2003;35:1491-1499
-
(2003)
Free Radic Biol Med
, vol.35
, pp. 1491-1499
-
-
Du, Y.1
Miller, C.2
Kern, T.3
-
138
-
-
0034993177
-
Hyperglycemia Potentiates Collagen-Induced Platelet Activation Through Mitochondrial Superoxide Overproduction
-
Yamagishi SI, Edelstein D, Du XL, Brownlee M. Hyperglycemia Potentiates Collagen-Induced Platelet Activation Through Mitochondrial Superoxide Overproduction. Diabetes 2001;50:1491-1494
-
(2001)
Diabetes
, vol.50
, pp. 1491-1494
-
-
Yamagishi, S.I.1
Edelstein, D.2
Du, X.L.3
Brownlee, M.4
-
139
-
-
0037180517
-
Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures
-
Tepper OM, Galiano RD, Capla JM, Kalka C, Gagne PJ, Jacobowitz GR, Levine JP, Gurtner GC. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 2002;106:2781-2786
-
(2002)
Circulation
, vol.106
, pp. 2781-2786
-
-
Tepper, O.M.1
Galiano, R.D.2
Capla, J.M.3
Kalka, C.4
Gagne, P.J.5
Jacobowitz, G.R.6
Levine, J.P.7
Gurtner, G.C.8
-
140
-
-
0036276672
-
Regulation of endothelial nitric oxide synthase activity and gene expression
-
Wu KK. Regulation of endothelial nitric oxide synthase activity and gene expression. Ann N Y Acad Sci 2002;962:122-130
-
(2002)
Ann N Y Acad Sci
, vol.962
, pp. 122-130
-
-
Wu, K.K.1
-
141
-
-
11144262141
-
Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells
-
Srinivasan S, Hatley ME, Bolick DT, Palmer LA, Edelstein D, Brownlee M, Hedrick CC. Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells. Diabetologia 2004;47:1727-1734
-
(2004)
Diabetologia
, vol.47
, pp. 1727-1734
-
-
Srinivasan, S.1
Hatley, M.E.2
Bolick, D.T.3
Palmer, L.A.4
Edelstein, D.5
Brownlee, M.6
Hedrick, C.C.7
-
142
-
-
0033867239
-
Effects of simulated hyperglycemia, insulin and glucagon on endothelial nitric oxide synthase expression
-
Ding Y, Vaziri ND, Coulson R, Kamanna VS, Roh DD. Effects of simulated hyperglycemia, insulin and glucagon on endothelial nitric oxide synthase expression. Am J Physiol Endocrinol Metab 2000;279:E11-E17
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Ding, Y.1
Vaziri, N.D.2
Coulson, R.3
Kamanna, V.S.4
Roh, D.D.5
-
143
-
-
0036637538
-
Homeostasis model assessment of insulin resistance in relation to the incidence of cardiovascular disease: The San Antonio Heart Study
-
Hanley AJ, Williams K, Stern MP, Haffner SM. Homeostasis model assessment of insulin resistance in relation to the incidence of cardiovascular disease: the San Antonio Heart Study. Diabetes Care 2002;25:1177-1184
-
(2002)
Diabetes Care
, vol.25
, pp. 1177-1184
-
-
Hanley, A.J.1
Williams, K.2
Stern, M.P.3
Haffner, S.M.4
-
144
-
-
0035814951
-
Endothelial regulation of vasomotion in apoE-deficient mice: Implications for interactions between peroxynitrite and tetrahydrobiopterin
-
Laursen JB, Somers M, Kurz S, McCann L, Warnholtz A, Freeman BA, Tarpey M, Fukai T, Harrison DG. Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin. Circulation 2001;103:1282-1288
-
(2001)
Circulation
, vol.103
, pp. 1282-1288
-
-
Laursen, J.B.1
Somers, M.2
Kurz, S.3
McCann, L.4
Warnholtz, A.5
Freeman, B.A.6
Tarpey, M.7
Fukai, T.8
Harrison, D.G.9
-
145
-
-
21644484482
-
Role of Nitrosative Stress and Poly(ADP-ribose) Polymerase Activation in Diabetic Vascular Dysfunction
-
Mabley JG, Soriano FG. Role of Nitrosative Stress and Poly(ADP-ribose) Polymerase Activation in Diabetic Vascular Dysfunction. Curr Vasc Pharmacol 2005;3:247-252
-
(2005)
Curr Vasc Pharmacol
, vol.3
, pp. 247-252
-
-
Mabley, J.G.1
Soriano, F.G.2
-
146
-
-
0034814670
-
Physiology and pathophysiology of poly(ADP-ribosyl)ation
-
Burkle A. Physiology and pathophysiology of poly(ADP-ribosyl)ation. Bioessays 2001;23:795-806
-
(2001)
Bioessays
, vol.23
, pp. 795-806
-
-
Burkle, A.1
-
147
-
-
0036710459
-
The functional role of poly(ADPribose) polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders
-
Hassa PO, Hottiger MO. The functional role of poly(ADPribose) polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders. Cell Mol Life Sci 2002;59:1534-1553
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 1534-1553
-
-
Hassa, P.O.1
Hottiger, M.O.2
-
148
-
-
0035796025
-
Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death
-
Herceg Z, Wang ZQ. Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutat Res 2001;477:97-110
-
(2001)
Mutat Res
, vol.477
, pp. 97-110
-
-
Herceg, Z.1
Wang, Z.Q.2
-
149
-
-
19444377566
-
Roles of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications
-
Szabo C. Roles of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications. Pharmacol Res 2005;52:60-71
-
(2005)
Pharmacol Res
, vol.52
, pp. 60-71
-
-
Szabo, C.1
-
150
-
-
0346093889
-
A radical explanation for glucose-induced beta cell dysfunction
-
Brownlee M. A radical explanation for glucose-induced beta cell dysfunction. J Clin Invest 2003;112:1788-1790
-
(2003)
J Clin Invest
, vol.112
, pp. 1788-1790
-
-
Brownlee, M.1
-
151
-
-
0142087597
-
-
Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study. JAMA 2003;290:2159-2167
-
Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study. JAMA 2003;290:2159-2167
-
-
-
-
152
-
-
0029147687
-
Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: A randomized prospective 6-year study
-
Ohkubo Y, Kishikawa H, Araki E, Miyata T, Isami S, Motoyoshi S, Kojima Y, Furuyoshi N, Shichiri M. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study. Diabetes Res Clin Pract 1995;28:103-117
-
(1995)
Diabetes Res Clin Pract
, vol.28
, pp. 103-117
-
-
Ohkubo, Y.1
Kishikawa, H.2
Araki, E.3
Miyata, T.4
Isami, S.5
Motoyoshi, S.6
Kojima, Y.7
Furuyoshi, N.8
Shichiri, M.9
-
153
-
-
85136423628
-
-
Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Effect of intensive therapy on the Microvascular complications of type 1 diabetes mellitus. JAMA 2002;287;2563-2569
-
Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Effect of intensive therapy on the Microvascular complications of type 1 diabetes mellitus. JAMA 2002;287;2563-2569
-
-
-
-
154
-
-
18844405709
-
Effect of intensive glycemic control on levels of markers of inflammation in type 1 diabetes mellitus in the diabetes control and complications trial
-
Schaumberg DA, Glynn RJ, Jenkins AJ, Lyons TJ, Rifai N, Manson JE, Ridker PM, Nathan DM. Effect of intensive glycemic control on levels of markers of inflammation in type 1 diabetes mellitus in the diabetes control and complications trial. Circulation 2005;111:2446-2453
-
(2005)
Circulation
, vol.111
, pp. 2446-2453
-
-
Schaumberg, D.A.1
Glynn, R.J.2
Jenkins, A.J.3
Lyons, T.J.4
Rifai, N.5
Manson, J.E.6
Ridker, P.M.7
Nathan, D.M.8
-
155
-
-
0032511566
-
-
UK Prospective Diabetes Study (UKPDS) Group: Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 1998;352(9131):854-865 Erratum in: Lancet 1998;352:1558
-
UK Prospective Diabetes Study (UKPDS) Group: Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 1998;352(9131):854-865 Erratum in: Lancet 1998;352:1558
-
-
-
-
156
-
-
0034628425
-
-
The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group: Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. N Engl J Med 2000;342:381-389
-
The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group: Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. N Engl J Med 2000;342:381-389
-
-
-
-
157
-
-
29144453326
-
Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes
-
Nathan DM, Cleary PA, Backlund JY, Genuth SM, Lachin JM, Orchard TJ, Raskin P, Zinman B. Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med 2005;353:2643-2653
-
(2005)
N Engl J Med
, vol.353
, pp. 2643-2653
-
-
Nathan, D.M.1
Cleary, P.A.2
Backlund, J.Y.3
Genuth, S.M.4
Lachin, J.M.5
Orchard, T.J.6
Raskin, P.7
Zinman, B.8
-
158
-
-
0031895701
-
The effect of intensive diabetes therapy on measures of autonomic nervous system function in the Diabetes Control and Complications Trial (DCCT)
-
Diabetes Control and Complications Trial Research Group
-
Diabetes Control and Complications Trial Research Group. The effect of intensive diabetes therapy on measures of autonomic nervous system function in the Diabetes Control and Complications Trial (DCCT). Diabetologia 1998;41:416-423
-
(1998)
Diabetologia
, vol.41
, pp. 416-423
-
-
-
159
-
-
85136439656
-
-
Diabetes Control and Complications Trial Research Group. Lifetime benefits of intensive therapy as practiced in the Diabetes Control and Complications Trial. JAMA 1996;276:1409-1415 Erratum in: JAMA 1997;278:25
-
Diabetes Control and Complications Trial Research Group. Lifetime benefits of intensive therapy as practiced in the Diabetes Control and Complications Trial. JAMA 1996;276:1409-1415 Erratum in: JAMA 1997;278:25
-
-
-
-
160
-
-
0037986208
-
Diabetes Control and Complications Trial; Epidemiology of Diabetes Interventions and Complications Research Group. Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus
-
Nathan DM, Lachin J, Cleary P, Orchard T, Brillon DJ, Backlund JY, O'Leary DH, Genuth S; Diabetes Control and Complications Trial; Epidemiology of Diabetes Interventions and Complications Research Group. Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus. N Engl J Med 2003;348:2294-22903
-
(2003)
N Engl J Med
, vol.348
, pp. 2294-22903
-
-
Nathan, D.M.1
Lachin, J.2
Cleary, P.3
Orchard, T.4
Brillon, D.J.5
Backlund, J.Y.6
O'Leary, D.H.7
Genuth, S.8
-
161
-
-
0037715390
-
The management of the obese diabetic patient
-
Albu J, Raja-Khan N. The management of the obese diabetic patient. Prim Care 2003;30:465-491
-
(2003)
Prim Care
, vol.30
, pp. 465-491
-
-
Albu, J.1
Raja-Khan, N.2
-
162
-
-
32144448938
-
Standards of Medical Care in Diabetes-2006
-
American diabetes Association
-
American diabetes Association. Standards of Medical Care in Diabetes-2006. Diabetes Care 2006;29:4-42
-
(2006)
Diabetes Care
, vol.29
, pp. 4-42
-
-
-
163
-
-
0036021977
-
Postprandial peaks as a risk factor for cardiovascular disease: Epidemiological perspectives
-
Bonora E. Postprandial peaks as a risk factor for cardiovascular disease: epidemiological perspectives. Int J Clin Pract Suppl 2002;129:5-11
-
(2002)
Int J Clin Pract Suppl
, vol.129
, pp. 5-11
-
-
Bonora, E.1
-
164
-
-
0035814611
-
Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of European prospective investigation of cancer and nutrition (EPIC-Norfolk)
-
Khaw KT, Wareham N, Luben R, Bingham S, Oakes S, Welch A, Day N. Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of European prospective investigation of cancer and nutrition (EPIC-Norfolk). BMJ 2001;322:15-18
-
(2001)
BMJ
, vol.322
, pp. 15-18
-
-
Khaw, K.T.1
Wareham, N.2
Luben, R.3
Bingham, S.4
Oakes, S.5
Welch, A.6
Day, N.7
-
165
-
-
0347133334
-
Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes
-
Saydah SH, Fradkin J, Cowie CC. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA 2004;291:335-342
-
(2004)
JAMA
, vol.291
, pp. 335-342
-
-
Saydah, S.H.1
Fradkin, J.2
Cowie, C.C.3
-
166
-
-
18144415490
-
Should minimal blood glucose variability become the gold standard of glycemic control?
-
Hirsch I, Brownlee M. Should minimal blood glucose variability become the gold standard of glycemic control? J Diabetes Complications 2005;19:178-181
-
(2005)
J Diabetes Complications
, vol.19
, pp. 178-181
-
-
Hirsch, I.1
Brownlee, M.2
-
167
-
-
0036021738
-
Nitrotyrosine: New findings as a marker of postprandial oxidative stress
-
Ceriello A. Nitrotyrosine: new findings as a marker of postprandial oxidative stress. Int J Clin Pract Suppl 2002;129:51-58
-
(2002)
Int J Clin Pract Suppl
, vol.129
, pp. 51-58
-
-
Ceriello, A.1
-
168
-
-
16844376137
-
The next generation of diabetic nephropathy therapies: An update
-
Williams ME, Tuttle KR. The next generation of diabetic nephropathy therapies: An update. Adv Chronic Kidney Dis 2005;12:212-222
-
(2005)
Adv Chronic Kidney Dis
, vol.12
, pp. 212-222
-
-
Williams, M.E.1
Tuttle, K.R.2
-
169
-
-
0034619027
-
Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): Randomised placebo controlled trial
-
Boaz M, Smetana S, Weinstein T, Matas Z, Gafter U, Iaina A, Knecht A, Weissgarten Y, Brunner D, Fainaru M, Green MS. Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo controlled trial. Lancet 2000;356: 1213-1218
-
(2000)
Lancet
, vol.356
, pp. 1213-1218
-
-
Boaz, M.1
Smetana, S.2
Weinstein, T.3
Matas, Z.4
Gafter, U.5
Iaina, A.6
Knecht, A.7
Weissgarten, Y.8
Brunner, D.9
Fainaru, M.10
Green, M.S.11
-
170
-
-
0034939115
-
The role of oxidative stress in the onset and progression of diabetes and its complications: A summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society
-
Rosen P, Nawroth PP, King G, Moller W, Tritschler HJ, Packer L. The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society. Diabetes Metab Res Rev 2001;17:189-212
-
(2001)
Diabetes Metab Res Rev
, vol.17
, pp. 189-212
-
-
Rosen, P.1
Nawroth, P.P.2
King, G.3
Moller, W.4
Tritschler, H.J.5
Packer, L.6
-
171
-
-
0035957267
-
Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans
-
Beckman JA, Goldfine AB, Gordon MB, Creager MA. Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans. Circulation 2001;103:1618-1623
-
(2001)
Circulation
, vol.103
, pp. 1618-1623
-
-
Beckman, J.A.1
Goldfine, A.B.2
Gordon, M.B.3
Creager, M.A.4
-
172
-
-
0032813888
-
High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes
-
Bursell SE, Clermont AC, Aiello LP, Aiello LM, Schlossman DK, Feener EP, Laffel L, King GL. High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes. Diabetes Care 1999;22:1245-1251
-
(1999)
Diabetes Care
, vol.22
, pp. 1245-1251
-
-
Bursell, S.E.1
Clermont, A.C.2
Aiello, L.P.3
Aiello, L.M.4
Schlossman, D.K.5
Feener, E.P.6
Laffel, L.7
King, G.L.8
-
173
-
-
0034700790
-
Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: Results of the HOPE study and MICRO-HOPE substudy
-
Heart Outcomes Prevention Evaluation Study Investigators
-
Heart Outcomes Prevention Evaluation Study Investigators. Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Lancet 2000;355:253-259
-
(2000)
Lancet
, vol.355
, pp. 253-259
-
-
-
174
-
-
0034773628
-
Molecular aspects of lipoic acid in the prevention of diabetes complications
-
Packer L, Kraemer K, Rimbach G. Molecular aspects of lipoic acid in the prevention of diabetes complications. Nutrition 2001;17:888-895
-
(2001)
Nutrition
, vol.17
, pp. 888-895
-
-
Packer, L.1
Kraemer, K.2
Rimbach, G.3
-
175
-
-
33646413409
-
Effect of R-(+)-alpha-lipoic acid on experimental diabetic retinopathy
-
Lin J, Bierhaus A, Bugert P, Dietrich N, Feng Y, Vom Hagen F, Nawroth P, Brownlee M, Hammes HP. Effect of R-(+)-alpha-lipoic acid on experimental diabetic retinopathy. Diabetologia 2006;49:1089-1096
-
(2006)
Diabetologia
, vol.49
, pp. 1089-1096
-
-
Lin, J.1
Bierhaus, A.2
Bugert, P.3
Dietrich, N.4
Feng, Y.5
Vom Hagen, F.6
Nawroth, P.7
Brownlee, M.8
Hammes, H.P.9
-
176
-
-
0034987312
-
The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: Potential role of p38 mitogen-activated protein kinase in GLUT4 activation
-
Konrad D, Somwar R, Sweeney G, Yaworsky K, Hayashi M, Ramlal T, Klip A. The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: Potential role of p38 mitogen-activated protein kinase in GLUT4 activation. Diabetes 2001;50:1464-1471
-
(2001)
Diabetes
, vol.50
, pp. 1464-1471
-
-
Konrad, D.1
Somwar, R.2
Sweeney, G.3
Yaworsky, K.4
Hayashi, M.5
Ramlal, T.6
Klip, A.7
-
177
-
-
0032788081
-
Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: A 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy
-
Ziegler D, Hanefeld M, Ruhnau KJ, Hasche H, Lobisch M, Schutte K, Kerum G, Malessa R. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy. Diabetes Care 1999;22:1296-1301
-
(1999)
Diabetes Care
, vol.22
, pp. 1296-1301
-
-
Ziegler, D.1
Hanefeld, M.2
Ruhnau, K.J.3
Hasche, H.4
Lobisch, M.5
Schutte, K.6
Kerum, G.7
Malessa, R.8
-
178
-
-
0031028636
-
Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie
-
Ziegler D, Schatz H, Conrad F, Gries FA, Ulrich H, Reichel G. Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie Diabetes Care 1997;20:369-373
-
(1997)
Diabetes Care
, vol.20
, pp. 369-373
-
-
Ziegler, D.1
Schatz, H.2
Conrad, F.3
Gries, F.A.4
Ulrich, H.5
Reichel, G.6
-
179
-
-
0030884244
-
Alpha-lipoic acid in the treatment of diabetic peripheral and cardiac autonomic neuropathy
-
Ziegler D, Gries FA. Alpha-lipoic acid in the treatment of diabetic peripheral and cardiac autonomic neuropathy. Diabetes 1997;46:S62-66
-
(1997)
Diabetes
, vol.46
-
-
Ziegler, D.1
Gries, F.A.2
-
180
-
-
0344837347
-
Benfotiamine blocks three major pathways of hyperglycaemic damage and prevents experimental diabetic retinopathy
-
Hammes HP, Du X, Edelstein D, Taguchi T, Matsumura T, Ju Q, Lin J, Bierhaus A, Nawroth P, Hannak D, Neumaier M, Bergfeld R, Giardino I, Brownlee M. Benfotiamine blocks three major pathways of hyperglycaemic damage and prevents experimental diabetic retinopathy. Nat Med 2003;9:294-299
-
(2003)
Nat Med
, vol.9
, pp. 294-299
-
-
Hammes, H.P.1
Du, X.2
Edelstein, D.3
Taguchi, T.4
Matsumura, T.5
Ju, Q.6
Lin, J.7
Bierhaus, A.8
Nawroth, P.9
Hannak, D.10
Neumaier, M.11
Bergfeld, R.12
Giardino, I.13
Brownlee, M.14
-
181
-
-
4344710760
-
Antihypertensive treatment and renal damage: Amlodipine exerts protective effect through the polyol pathway
-
Bernobich E, Cosenzi A, Campa C, Zennaro C, Sasso F, Paoletti S, Bellini G. Antihypertensive treatment and renal damage: amlodipine exerts protective effect through the polyol pathway. Cardiovasc Pharmacol 2004;44:401-406
-
(2004)
Cardiovasc Pharmacol
, vol.44
, pp. 401-406
-
-
Bernobich, E.1
Cosenzi, A.2
Campa, C.3
Zennaro, C.4
Sasso, F.5
Paoletti, S.6
Bellini, G.7
-
182
-
-
0343048978
-
Improvement of nitric oxide-dependent vasodilation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation
-
Wagner AH, Kohler T, Ruckschloss U, Just I, Hecker M. Improvement of nitric oxide-dependent vasodilation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation. Arterioscler Thromb Vasc Biol 2000;20:61-69
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 61-69
-
-
Wagner, A.H.1
Kohler, T.2
Ruckschloss, U.3
Just, I.4
Hecker, M.5
-
183
-
-
0037178764
-
Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice
-
Vecchione C, Brandes RP. Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice. Circ Res 2002;91:173-179
-
(2002)
Circ Res
, vol.91
, pp. 173-179
-
-
Vecchione, C.1
Brandes, R.P.2
-
184
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Brenner BM, Cooper ME, de Zeeuw D, Keane WF, Mitch WE, Parving HH, Remuzzi G, Snapinn SM, Zhang Z, Shahinfar SN. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001;345:861-869
-
(2001)
N Engl J Med
, vol.345
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
de Zeeuw, D.3
Keane, W.F.4
Mitch, W.E.5
Parving, H.H.6
Remuzzi, G.7
Snapinn, S.M.8
Zhang, Z.9
Shahinfar, S.N.10
-
185
-
-
33644749330
-
Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells
-
Kukidome D, Nishikawa T, Sonoda K, Imoto K, Fujisawa K, Yano M, Motoshima H, Taguchi T, Matsumura T, Araki E. Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells. Diabetes 2006;55:120-127
-
(2006)
Diabetes
, vol.55
, pp. 120-127
-
-
Kukidome, D.1
Nishikawa, T.2
Sonoda, K.3
Imoto, K.4
Fujisawa, K.5
Yano, M.6
Motoshima, H.7
Taguchi, T.8
Matsumura, T.9
Araki, E.10
|