Aldose reductase is an obligatory mediator of the late phase of ischemic preconditioning

Circulation Research

Volumn 91, Issue 3, 2002, Pages 240-246

  Shinmura, Ken ^a   Bolli, Roberto ^a   Liu, Si Qi ^a   Tang, Xian Liang ^a   Kodani, Eitaro ^a   Xuan, Yu ting ^a   Srivastava, Sanjay ^a   Bhatnagar, Aruni ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

4 Hydroxy trans 2 nonenal; Aldose reductase; Ischemic preconditioning; Myocardial infarction; Myocardial ischemia reperfusion injury

Indexed keywords

4 HYDROXYNONENAL; ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; CHELERYTHRINE; N(G) NITROARGININE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; SORBINIL; SORBITOL; TOLRESTAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HEART INFARCTION; HEART INFARCTION PREVENTION; HEART MUSCLE REPERFUSION; HEART PROTECTION; LIPID PEROXIDATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

ALDEHYDE REDUCTASE; ALDEHYDES; ANIMALS; CARDIOTONIC AGENTS; HEMODYNAMIC PROCESSES; ISCHEMIC PRECONDITIONING, MYOCARDIAL; KINETICS; L-IDITOL 2-DEHYDROGENASE; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; RABBITS; SORBITOL;

EID: 0037047696     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000029970.97247.57     Document Type: Article

References (34)

1. Comparative anatomy of the aldo-keto reductase superfamily
2. Aldose reductase, congenial and injurious profiles of an enigmatic enzyme
3. Structural and kinetic determinants of aldehyde reduction by aldose reductase
4. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
5. Free radicals and their involvement during long-term myocardial ischemia and reperfusion
6. 4-Hydroxynonenal, a novel indicator of lipid peroxidation for reperfusion injury of the myocardium
7. Cardiac reperfusion injury: Aging, lipid peroxidation, and mitochondrial dysfunction
8. Formation of 4-hydroxy-2-nonenal-modified proteins in ischemic rat heart
9. Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction
10. Genistein, a tyrosine kinase inhibitor, blocks the "second window of protection" 48 h after ischemic preconditioning in the rabbit
11. Evidence that late preconditioning against myocardial stunning in conscious rabbits is triggered by the generation of nitric oxide
12. The protective effect of late preconditioning against myocardial stunning in conscious rabbits is mediated by nitric oxide synthase. Evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning
13. Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that epsilon is the isoform involved
14. Isoform-selective activation of protein kinase C by nitric oxide in the heart of conscious rabbits: A signaling mechanism for both nitric oxide-induced and ischemia-induced preconditioning
15. The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase gene
16. Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of ischemic preconditioning in conscious rabbits
17. The late phase of preconditioning
18. Opening of mitochondrial KATP channel induces early and delayed cardioprotective effect: Role of nitric oxide
19. Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis
20. Aldose reductase induction: A novel response to oxidative stress of smooth muscle cells
21. 1 receptors: Evidence from gene-knockout mice
22. Involvement of protein kinase C in the delayed cytoprotection following sublethal ischaemia in rabbit myocardium
23. Demonstration of free radical generation in the "stunned" myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs
24. Involvement of aldose reductase in vascular smooth muscle cell growth and lesion formation after arterial injury
25. Aldose reductase inhibition protects diabetic and nondiabetic rat hearts from ischemic injury
26. Aldose reductase inhibition alone or combined with an adenosine A3 agonist reduces ischemic myocardial injury
27. Determination of aldehydes and other lipid peroxidation products in biological samples by gas chromatography-mass spectrometry
28. Metabolism of base propenals in the heart: The role of aldose reductase in detoxifying mutagenic and cytotoxic products of DNA damage
29. Cardiac metabolism of enals
30. Metabolism of the lipid peroxidation product, 4-hydroxy-trans-2-nonenal, in isolated perfused rat heart
31. Decreased SLM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays
32. Electrophysiological effects of 4-hydroxynonenal, an aldehydic product of lipid peroxidation, on isolated rat ventricular myocytes
33. Contribution of leukocyte infiltration to lipid peroxidation occurring in the non-ischemic region of the rat heart submitted to permanent left coronary artery occlusion
34. Evidence for increased lipid peroxidation products in the non-ischemic portion of the heart with coronary occlusion