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Volumn 12, Issue 2, 2005, Pages 212-222

The next generation of diabetic nephropathy therapies: An update

Author keywords

Advanced glycation end product inhibition; Diabetic nephropathy; Novel therapies; Protein kinase C inhibition; Sulodexide, pyridoxamine

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALAGEBRIUM; ANTIDIABETIC AGENT; DANAPAROID; DERMATAN SULFATE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; PROTEIN KINASE C BETA; PROTEIN KINASE C INHIBITOR; PYRIDORIN; PYRIDOXAMINE; RUBOXISTAURIN; SULODEXIDE; UNCLASSIFIED DRUG;

EID: 16844376137     PISSN: 15485595     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ackd.2005.01.011     Document Type: Article
Times cited : (31)

References (89)
  • 2
    • 0041883730 scopus 로고    scopus 로고
    • The importance of diabetic nephropathy in current nephrological practice
    • F. Locatelli, B. Canaud, K.U. Eckardt The importance of diabetic nephropathy in current nephrological practice Nephrol Dial Transplant 8 2003 716 725
    • (2003) Nephrol Dial Transplant , vol.8 , pp. 716-725
    • Locatelli, F.1    Canaud, B.2    Eckardt, K.U.3
  • 3
    • 0038512408 scopus 로고    scopus 로고
    • The contribution of increased diabetes prevalence and improved myocardial infarction and stroke survival to the increase in treated end-stage renal disease
    • P. Muntner, J. Coresh, N.R. Power The contribution of increased diabetes prevalence and improved myocardial infarction and stroke survival to the increase in treated end-stage renal disease J Am Soc Nephrol 14 2003 1568 1577
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1568-1577
    • Muntner, P.1    Coresh, J.2    Power, N.R.3
  • 4
    • 0041344905 scopus 로고    scopus 로고
    • Annual Data Report 2001: Incidence and prevalence of ESRD
    • United States Renal Data System
    • United States Renal Data System Annual Data Report 2001 Incidence and prevalence of ESRD Am J Kidney Dis 38 suppl 2001 S37 S52
    • (2001) Am J Kidney Dis , vol.38 , Issue.SUPPL.
  • 5
    • 25444479816 scopus 로고    scopus 로고
    • Annual Data Report 2003: Incidence and prevalence of ESRD
    • United States Renal Data System
    • United States Renal Data System Annual Data Report 2003 Incidence and prevalence of ESRD Am J Kidney Dis 42 suppl 2003 S47 S60
    • (2003) Am J Kidney Dis , vol.42 , Issue.SUPPL.
  • 6
    • 14044256959 scopus 로고    scopus 로고
    • U.S. Renal Data System National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases Bethesda, MD
    • U.S. Renal Data System USRDS 2004 Annual Data Report: Atlas of End-Stage Renal Disease in the United States. 2004 National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases Bethesda, MD
    • (2004) USRDS 2004 Annual Data Report: Atlas of End-Stage Renal Disease in the United States.
  • 7
    • 1542513681 scopus 로고    scopus 로고
    • The health care costs of diabetic nephropathy in the United States and the United Kingdom
    • A. Gordois, P. Scuffham, A. Shearer The health care costs of diabetic nephropathy in the United States and the United Kingdom J Diabetes Complications 18 2004 18 26
    • (2004) J Diabetes Complications , vol.18 , pp. 18-26
    • Gordois, A.1    Scuffham, P.2    Shearer, A.3
  • 8
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus N Engl J Med 329 1993 977 986
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 9
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood glucose control with sulfonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group Intensive blood glucose control with sulfonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) Lancet 352 1998 837 853
    • (1998) Lancet , vol.352 , pp. 837-853
  • 10
    • 0034071036 scopus 로고    scopus 로고
    • Long-term results of the Kumamoto study on optimal diabetes control in type 2 diabetic patients
    • M. Shichiri, H. Kishikawa, Y. Ohkubo Long-term results of the Kumamoto study on optimal diabetes control in type 2 diabetic patients Diabetes Care 23 2000 B21 B29
    • (2000) Diabetes Care , vol.23
    • Shichiri, M.1    Kishikawa, H.2    Ohkubo, Y.3
  • 11
    • 0027160570 scopus 로고
    • Effective antihypertensive treatment postpones renal insufficiency in diabetic nephropathy
    • H.H. Parving, U.M. Smidt, E. Hommel Effective antihypertensive treatment postpones renal insufficiency in diabetic nephropathy Am J Kidney Dis 22 1993 188 195
    • (1993) Am J Kidney Dis , vol.22 , pp. 188-195
    • Parving, H.H.1    Smidt, U.M.2    Hommel, E.3
  • 12
    • 0027517659 scopus 로고
    • The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy
    • E.J. Lewis, L.G. Hunsicker, R.P. Bain The effect of angiotensin- converting-enzyme inhibition on diabetic nephropathy N Engl J Med 329 1993 1456 1462
    • (1993) N Engl J Med , vol.329 , pp. 1456-1462
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3
  • 13
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • B.M. Brenner, M.E. Cooper, D. de Zeeuw Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy N Engl J Med 345 2001 861 869
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    De Zeeuw, D.3
  • 14
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • E.J. Lewis, L.G. Hunsicker, W.R. Clarke Renoprotective effect of the angiotensin receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes N Engl J Med 345 2001 851 860
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 15
    • 0029917114 scopus 로고    scopus 로고
    • The effect of dietary protein restriction on the progression of diabetic and nondiabetic renal diseases: A meta-analysis
    • M.T. Pedrini, A.S. Levey, J. Lau The effect of dietary protein restriction on the progression of diabetic and nondiabetic renal diseases A meta-analysis Ann Intern Med 124 1996 627 632
    • (1996) Ann Intern Med , vol.124 , pp. 627-632
    • Pedrini, M.T.1    Levey, A.S.2    Lau, J.3
  • 16
    • 0031779392 scopus 로고    scopus 로고
    • A meta-analysis of the effects of dietary protein restriction on the rate of decline in renal function
    • B.L. Kasiske, J.D.A. Lakatua, J.Z. Ma A meta-analysis of the effects of dietary protein restriction on the rate of decline in renal function Am J Kidney Dis 31 1998 954 961
    • (1998) Am J Kidney Dis , vol.31 , pp. 954-961
    • Kasiske, B.L.1    Lakatua, J.D.A.2    Ma, J.Z.3
  • 17
    • 0036311086 scopus 로고    scopus 로고
    • Effect of dietary protein restriction on prognosis in patients with diabetic nephropathy
    • H.P. Hansen, E. Tauber-Lassen, B.R. Jensen Effect of dietary protein restriction on prognosis in patients with diabetic nephropathy Kidney Int 62 2002 220 228
    • (2002) Kidney Int , vol.62 , pp. 220-228
    • Hansen, H.P.1    Tauber-Lassen, E.2    Jensen, B.R.3
  • 18
    • 0037472879 scopus 로고    scopus 로고
    • Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes
    • P. Gaede, P. Vedel, N. Larsen Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes N Engl J Med 348 2003 383 393
    • (2003) N Engl J Med , vol.348 , pp. 383-393
    • Gaede, P.1    Vedel, P.2    Larsen, N.3
  • 19
    • 15844397902 scopus 로고    scopus 로고
    • Intravenous administration of heypatocyte growth factor gene ameliorates diabetic nephropathy in mice
    • C. Dai, J. Yang, S. Bastacky Intravenous administration of heypatocyte growth factor gene ameliorates diabetic nephropathy in mice J Am Soc Nephrol 15 2004 2637 2647
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2637-2647
    • Dai, C.1    Yang, J.2    Bastacky, S.3
  • 20
    • 0142089894 scopus 로고    scopus 로고
    • Blockade of receptor for advanced glycation end products: A new target for therapeutic intervention in diabetic complications and inflammatory disorders
    • B.I. Hudson, L.G. Bucciarelli, T. Wendt Blockade of receptor for advanced glycation end products A new target for therapeutic intervention in diabetic complications and inflammatory disorders Arch Biochem Biophys 419 2003 80 88
    • (2003) Arch Biochem Biophys , vol.419 , pp. 80-88
    • Hudson, B.I.1    Bucciarelli, L.G.2    Wendt, T.3
  • 21
    • 0028283295 scopus 로고
    • Amelioration of diabetic nephropathy by treatment with monoclonal antibodies against glycated albumin
    • M.P. Cohen, E. Hud, V.-Y. Wu Amelioration of diabetic nephropathy by treatment with monoclonal antibodies against glycated albumin Kidney Int 45 1994 1673 1679
    • (1994) Kidney Int , vol.45 , pp. 1673-1679
    • Cohen, M.P.1    Hud, E.2    Wu, V.-Y.3
  • 22
    • 0142122027 scopus 로고    scopus 로고
    • Intervention strategies to prevent pathogenetic effects of glycated albumin
    • M.P. Cohen Intervention strategies to prevent pathogenetic effects of glycated albumin Arch Biochem Biophys 419 2003 25 30
    • (2003) Arch Biochem Biophys , vol.419 , pp. 25-30
    • Cohen, M.P.1
  • 23
    • 16644370226 scopus 로고    scopus 로고
    • Tranilast attenuates structural and functional aspects of renal injury in the remnant kidney model
    • D.J. Kelly, Y. Zhang, R. Gow Tranilast attenuates structural and functional aspects of renal injury in the remnant kidney model J Am Soc Nephrol 15 2004 2619 2629
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2619-2629
    • Kelly, D.J.1    Zhang, Y.2    Gow, R.3
  • 24
    • 10744223527 scopus 로고    scopus 로고
    • Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy
    • W.K. Bolton, D.C. Cattran, M.E. Williams Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy Am J Nephrol 24 2004 32 40
    • (2004) Am J Nephrol , vol.24 , pp. 32-40
    • Bolton, W.K.1    Cattran, D.C.2    Williams, M.E.3
  • 25
    • 0036014944 scopus 로고    scopus 로고
    • Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: The Di.N.A.S. randomized trial
    • G. Gambaro, I. Kinalska, A. Oksa Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: The Di.N.A.S. randomized trial J Am Soc Nephrol 13 2002 1615 1625
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1615-1625
    • Gambaro, G.1    Kinalska, I.2    Oksa, A.3
  • 26
    • 0031938089 scopus 로고    scopus 로고
    • Pharmacological actions of sulodexide
    • F.A. Ofosu Pharmacological actions of sulodexide Semin Thromb Hemost 24 1998 127 138
    • (1998) Semin Thromb Hemost , vol.24 , pp. 127-138
    • Ofosu, F.A.1
  • 27
    • 0033672331 scopus 로고    scopus 로고
    • Glycosaminoglycan therapy prevents TGF-B1 overexpression and pathologic changes in renal tissue of long-term diabetic rats
    • M. Ceol, G. Gambaro, U. Sauer Glycosaminoglycan therapy prevents TGF-B1 overexpression and pathologic changes in renal tissue of long-term diabetic rats J Am Soc Nephrol 11 2000 2324 2336
    • (2000) J Am Soc Nephrol , vol.11 , pp. 2324-2336
    • Ceol, M.1    Gambaro, G.2    Sauer, U.3
  • 28
    • 0028092966 scopus 로고
    • Treatment with glycosaminoglycan formulation ameliorates experimental diabetic nephropathy
    • G. Gambaro, A.P. Venturini, D.M. Noonan Treatment with glycosaminoglycan formulation ameliorates experimental diabetic nephropathy Kidney Int 46 1994 797 806
    • (1994) Kidney Int , vol.46 , pp. 797-806
    • Gambaro, G.1    Venturini, A.P.2    Noonan, D.M.3
  • 29
    • 0026659040 scopus 로고
    • Glycosaminoglycans prevent morphological renal alterations and albuminuria in diabetic rats
    • G. Gambaro, A.O. Cavazzana, P. Luzi Glycosaminoglycans prevent morphological renal alterations and albuminuria in diabetic rats Kidney Int 42 1992 285 291
    • (1992) Kidney Int , vol.42 , pp. 285-291
    • Gambaro, G.1    Cavazzana, A.O.2    Luzi, P.3
  • 30
    • 0024319532 scopus 로고
    • Heparin stimulates the synthesis and modifies the sulfation pattern of heparan sulfate proteoglycan from endothelial cells
    • H.B. Nader, V. Buonassisi, P. Colburn Heparin stimulates the synthesis and modifies the sulfation pattern of heparan sulfate proteoglycan from endothelial cells J Cell Physiol 140 1989 305 310
    • (1989) J Cell Physiol , vol.140 , pp. 305-310
    • Nader, H.B.1    Buonassisi, V.2    Colburn, P.3
  • 31
    • 0028937724 scopus 로고
    • Heparin modulates proliferation and proteoglycan biosynthesis in murine mesangial cells: Molecular clues for its activity in nephropathy
    • C. Caenazzo, S. Garbisa, M. Ceol Heparin modulates proliferation and proteoglycan biosynthesis in murine mesangial cells Molecular clues for its activity in nephropathy Nephrol Dial Transplant 20 1995 175 184
    • (1995) Nephrol Dial Transplant , vol.20 , pp. 175-184
    • Caenazzo, C.1    Garbisa, S.2    Ceol, M.3
  • 32
    • 0029869563 scopus 로고    scopus 로고
    • Glycosaminoglycans: A new paradigm in the prevention of proteinuria and progression of glomerular disease
    • G. Gambaro, B. Baggio Glycosaminoglycans A new paradigm in the prevention of proteinuria and progression of glomerular disease Nephrol Dial Transplant 11 1996 762 764
    • (1996) Nephrol Dial Transplant , vol.11 , pp. 762-764
    • Gambaro, G.1    Baggio, B.2
  • 33
    • 0030957881 scopus 로고    scopus 로고
    • Glycosaminoglycans delay the progression of nephropathy in NIDDM
    • A. Solini, L. Vergnani, F. Ricci Glycosaminoglycans delay the progression of nephropathy in NIDDM Diabetes Care 20 1997 819 823
    • (1997) Diabetes Care , vol.20 , pp. 819-823
    • Solini, A.1    Vergnani, L.2    Ricci, F.3
  • 34
    • 0029922805 scopus 로고    scopus 로고
    • Glycosaminoglycans oral therapy reduces macroalbuminuria, blood fibrinogen levels and limb arteriopathy clinical signs in patients with non-insulin dependent diabetes mellitus
    • M. Velussi, A.M. Cernigoi, F. Dapas Glycosaminoglycans oral therapy reduces macroalbuminuria, blood fibrinogen levels and limb arteriopathy clinical signs in patients with non-insulin dependent diabetes mellitus Diabetes Nutr Metab 9 1996 53 58
    • (1996) Diabetes Nutr Metab , vol.9 , pp. 53-58
    • Velussi, M.1    Cernigoi, A.M.2    Dapas, F.3
  • 35
    • 0031408776 scopus 로고    scopus 로고
    • Effect of glycosaminoglycans on urinary albumin excretion in insulin-dependent diabetic patients with micro- or macroalbuminuria
    • A. Poplawska, M. Szelachowska, B. Topolska Effect of glycosaminoglycans on urinary albumin excretion in insulin-dependent diabetic patients with micro- or macroalbuminuria Diabetes Res Clin Pract 38 1997 109 114
    • (1997) Diabetes Res Clin Pract , vol.38 , pp. 109-114
    • Poplawska, A.1    Szelachowska, M.2    Topolska, B.3
  • 36
    • 0034003453 scopus 로고    scopus 로고
    • Advanced glycation end-products: A nephrologist's perspective
    • D.S.C. Raj, D. Choudhury, T.C. Welbourne Advanced glycation end-products A nephrologist's perspective Am J Kidney Dis 35 2000 365 380
    • (2000) Am J Kidney Dis , vol.35 , pp. 365-380
    • Raj, D.S.C.1    Choudhury, D.2    Welbourne, T.C.3
  • 37
    • 0034817423 scopus 로고    scopus 로고
    • Advanced glycation end products and the progressive course of renal disease
    • A. Heidland, K. Sebekova, R. Schinzel Advanced glycation end products and the progressive course of renal disease Am J Kidney Dis 38 suppl 1 2001 S100 S106
    • (2001) Am J Kidney Dis , vol.38 , Issue.SUPPL. 1
    • Heidland, A.1    Sebekova, K.2    Schinzel, R.3
  • 38
    • 0041364626 scopus 로고    scopus 로고
    • Role of advanced glycation end products in diabetic nephropathy
    • J.M. Forbes, M.E. Cooper, M.D. Oldfield Role of advanced glycation end products in diabetic nephropathy J Am Soc Nephrol 14 suppl 2003 S54 S58
    • (2003) J Am Soc Nephrol , vol.14 , Issue.SUPPL.
    • Forbes, J.M.1    Cooper, M.E.2    Oldfield, M.D.3
  • 39
    • 0037374652 scopus 로고    scopus 로고
    • New therapies for advanced glycation end product nephrotoxicity: Current challenges
    • M.E. Williams New therapies for advanced glycation end product nephrotoxicity Current challenges Am J Kidney Dis 41 suppl 1 2003 S42 S47
    • (2003) Am J Kidney Dis , vol.41 , Issue.SUPPL. 1
    • Williams, M.E.1
  • 40
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 414 2001 813 820
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 41
    • 3042668028 scopus 로고    scopus 로고
    • Enhanced expression of receptor for advanced glycation end products in chronic kidney disease
    • F.F. Hou, H. Ren, W.F. Owen Enhanced expression of receptor for advanced glycation end products in chronic kidney disease J Am Soc Nephrol 15 2004 1889 1896
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1889-1896
    • Hou, F.F.1    Ren, H.2    Owen, W.F.3
  • 42
    • 4143087382 scopus 로고    scopus 로고
    • Advanced glycation end product (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells
    • C. Lu, J.C. He, W. Cai Advanced glycation end product (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells Proc Natl Acad Sci USA 101 2004 11767 11772
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11767-11772
    • Lu, C.1    He, J.C.2    Cai, W.3
  • 43
    • 0142089900 scopus 로고    scopus 로고
    • Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease
    • G. Jerums, S. Panagiotopoulos, J. Forbes Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease Arch Biochem Biophysics 419 2003 55 62
    • (2003) Arch Biochem Biophysics , vol.419 , pp. 55-62
    • Jerums, G.1    Panagiotopoulos, S.2    Forbes, J.3
  • 44
    • 0026615956 scopus 로고
    • Early glycosylation products induce glomerular hyperfiltration in normal rats
    • M. Sabbatini, G. Sansone, F. Uccello Early glycosylation products induce glomerular hyperfiltration in normal rats Kidney Int 42 1992 875 881
    • (1992) Kidney Int , vol.42 , pp. 875-881
    • Sabbatini, M.1    Sansone, G.2    Uccello, F.3
  • 45
    • 0031823456 scopus 로고    scopus 로고
    • Immunocytochemical detectin of advanced glycated end products in rat renal tissue as a function of age and diabetes
    • M. Bendayan Immunocytochemical detectin of advanced glycated end products in rat renal tissue as a function of age and diabetes Kidney Int 54 1998 438 447
    • (1998) Kidney Int , vol.54 , pp. 438-447
    • Bendayan, M.1
  • 46
    • 0009770755 scopus 로고    scopus 로고
    • Effect of diabetes and aminoguanidine therapy on renal advanced glycation end-product binding
    • S. Youssef, D.T. Nguyen, T. Soulis Effect of diabetes and aminoguanidine therapy on renal advanced glycation end-product binding Kidney Int 55 1999 907 916
    • (1999) Kidney Int , vol.55 , pp. 907-916
    • Youssef, S.1    Nguyen, D.T.2    Soulis, T.3
  • 47
  • 48
    • 12144257117 scopus 로고    scopus 로고
    • Clinical studies of advanced glycation end-product inhibitors and diabetic kidney disease
    • M.E. Williams Clinical studies of advanced glycation end-product inhibitors and diabetic kidney disease Curr Diabetes Rep 4 2004 441 446
    • (2004) Curr Diabetes Rep , vol.4 , pp. 441-446
    • Williams, M.E.1
  • 49
    • 0442277569 scopus 로고    scopus 로고
    • Advanced glycation end products in clinical nephrology
    • M. Kalousova, T. Zima, V. Vesai Advanced glycation end products in clinical nephrology Kidney Blood Press Res 27 2004 18 28
    • (2004) Kidney Blood Press Res , vol.27 , pp. 18-28
    • Kalousova, M.1    Zima, T.2    Vesai, V.3
  • 50
    • 0026575313 scopus 로고
    • Mechanistic studies of advanced glycosylation end product inhibition by aminoguanidine
    • D. Edelstein, M. Brownlee Mechanistic studies of advanced glycosylation end product inhibition by aminoguanidine Diabetes 41 1992 26 29
    • (1992) Diabetes , vol.41 , pp. 26-29
    • Edelstein, D.1    Brownlee, M.2
  • 51
    • 0142058743 scopus 로고    scopus 로고
    • Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: A novel therapy for treatment of diabetic complications
    • T.O. Metz, N.L. Alderson, S.R. Thorpe Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions A novel therapy for treatment of diabetic complications Arch Biochem Biophys 419 2003 41 49
    • (2003) Arch Biochem Biophys , vol.419 , pp. 41-49
    • Metz, T.O.1    Alderson, N.L.2    Thorpe, S.R.3
  • 52
    • 0038527321 scopus 로고    scopus 로고
    • The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats
    • N.L. Alderson, M.E. Chachich, N.Y. Youssef The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats Kidney Int 63 2003 2123 2133
    • (2003) Kidney Int , vol.63 , pp. 2123-2133
    • Alderson, N.L.1    Chachich, M.E.2    Youssef, N.Y.3
  • 53
    • 0036183727 scopus 로고    scopus 로고
    • Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat
    • T.P. Degenhardt, N.L. Alderson, D.D. Arrington Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat Kidney Int 61 2000 939 950
    • (2000) Kidney Int , vol.61 , pp. 939-950
    • Degenhardt, T.P.1    Alderson, N.L.2    Arrington, D.D.3
  • 54
    • 0036723821 scopus 로고    scopus 로고
    • The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes
    • A. Stitt, T.A. Gardiner, N.L. Anderson The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes Diabetes 51 2002 2826 2832
    • (2002) Diabetes , vol.51 , pp. 2826-2832
    • Stitt, A.1    Gardiner, T.A.2    Anderson, N.L.3
  • 55
    • 12144263911 scopus 로고    scopus 로고
    • A phase 2 clinical trial of pyridoxamine (Pyridorin) in type 2 and type 2 diabetic patients with overt nephropathy (PYR-206)
    • M.E. Williams, W.K. Bolton, T.P. Degenhardt A phase 2 clinical trial of pyridoxamine (Pyridorin) in type 2 and type 2 diabetic patients with overt nephropathy (PYR-206) J Am Soc Nephrol 14 2003 7A
    • (2003) J Am Soc Nephrol , vol.14
    • Williams, M.E.1    Bolton, W.K.2    Degenhardt, T.P.3
  • 56
    • 0020592458 scopus 로고
    • Sensory neuropathy from pyridoxine abuse: A new megavitamin syndrome
    • H. Schaumburg, J. Kaplan, A. Windebakn Sensory neuropathy from pyridoxine abuse A new megavitamin syndrome N Engl J Med 309 1983 445 448
    • (1983) N Engl J Med , vol.309 , pp. 445-448
    • Schaumburg, H.1    Kaplan, J.2    Windebakn, A.3
  • 57
    • 0036786046 scopus 로고    scopus 로고
    • Angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors lower in vitro the formation of advanced glycation end products: Biochemical mechanisms
    • T. Miiyata, C. Van Ypersele de Strihou, Y. Euda Angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors lower in vitro the formation of advanced glycation end products Biochemical mechanisms J Am Soc Nephrol 13 2002 2478 2487
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2478-2487
    • Miiyata, T.1    Vanyperselede Strihou, C.2    Euda, Y.3
  • 58
    • 16844366468 scopus 로고    scopus 로고
    • A phase 2 clinical investigation of pyridoxamine (Pyridorine) in type 1 and type 2 diabetic patients with overt diabetic nephropathy (PYR 205-207)
    • J.B. McGill, M.E. Williams, T.P. Degenhardt A phase 2 clinical investigation of pyridoxamine (Pyridorine) in type 1 and type 2 diabetic patients with overt diabetic nephropathy (PYR 205-207) J Am Soc Nephrol 15 2004 565A
    • (2004) J Am Soc Nephrol , vol.15
    • McGill, J.B.1    Williams, M.E.2    Degenhardt, T.P.3
  • 59
    • 0142121508 scopus 로고    scopus 로고
    • Therapeutic potential of breakers of advanced glycation end product-protein crosslinks
    • S. Vasan, P. Foiles, H. Founds Therapeutic potential of breakers of advanced glycation end product-protein crosslinks Arch Biochem Biophys 419 2003 89 96
    • (2003) Arch Biochem Biophys , vol.419 , pp. 89-96
    • Vasan, S.1    Foiles, P.2    Founds, H.3
  • 60
    • 0142029114 scopus 로고    scopus 로고
    • Novel inhibitors of advanced glycation end products
    • S. Rahbar, J.L. Figarola Novel inhibitors of advanced glycation end products Arch Biochem Biophys 419 2003 63 79
    • (2003) Arch Biochem Biophys , vol.419 , pp. 63-79
    • Rahbar, S.1    Figarola, J.L.2
  • 61
    • 0032401898 scopus 로고    scopus 로고
    • Mechanisms of maturation of ageing of collagen
    • A.J. Bailey, R.G. Paul, L. Knott Mechanisms of maturation of ageing of collagen Mech Ageing Dev 106 1998 1 56
    • (1998) Mech Ageing Dev , vol.106 , pp. 1-56
    • Bailey, A.J.1    Paul, R.G.2    Knott, L.3
  • 62
    • 0035135246 scopus 로고    scopus 로고
    • Advanced glycation end-products: A review
    • R. Singh, A. Barden, T. Mori Advanced glycation end-products A review Diabetologia 44 2001 129 146
    • (2001) Diabetologia , vol.44 , pp. 129-146
    • Singh, R.1    Barden, A.2    Mori, T.3
  • 63
    • 0027291535 scopus 로고
    • Aminoguanidine treatment increases elasticity and decreases fluid filtration of large arteries from diabetic rats
    • M.S.P. Huijberts, B.H.R. Wolffenbuttel, H. Boudier Aminoguanidine treatment increases elasticity and decreases fluid filtration of large arteries from diabetic rats J Clin Invest 92 1993 1407 1411
    • (1993) J Clin Invest , vol.92 , pp. 1407-1411
    • Huijberts, M.S.P.1    Wolffenbuttel, B.H.R.2    Boudier, H.3
  • 64
    • 0022644227 scopus 로고
    • Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking
    • M. Brownlee, H. Vlassara, A. Kooney Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking Science 232 1986 1629 1632
    • (1986) Science , vol.232 , pp. 1629-1632
    • Brownlee, M.1    Vlassara, H.2    Kooney, A.3
  • 65
    • 15844425230 scopus 로고    scopus 로고
    • An agent cleaving glucose-derived protein crosslinks in vitro and in vivo
    • S. Vasan, X. Zhang, X. Zhang An agent cleaving glucose-derived protein crosslinks in vitro and in vivo Nature 382 1996 275 278
    • (1996) Nature , vol.382 , pp. 275-278
    • Vasan, S.1    Zhang, X.2    Zhang, X.3
  • 66
    • 7044231909 scopus 로고    scopus 로고
    • Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711, a protein kinase C-alpha-dependent pathway
    • V. Tallas-Bonke, C. Lindschau, B. Rizkalla Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711, a protein kinase C-alpha-dependent pathway Diabetes 53 2004 2921 2930
    • (2004) Diabetes , vol.53 , pp. 2921-2930
    • Tallas-Bonke, V.1    Lindschau, C.2    Rizkalla, B.3
  • 67
    • 1842510005 scopus 로고    scopus 로고
    • Cardiovascular and renal effects of a collagen cross-link breaker (ALT-711) in adult and aged spontaneously hypertensive rats
    • D. Susic, J. Varagic, J. Ahn Cardiovascular and renal effects of a collagen cross-link breaker (ALT-711) in adult and aged spontaneously hypertensive rats AJH 17 2004 328 333
    • (2004) AJH , vol.17 , pp. 328-333
    • Susic, D.1    Varagic, J.2    Ahn, J.3
  • 68
    • 0035949502 scopus 로고    scopus 로고
    • Improved arterial compliance by a novel advanced glycation end-product crosslink breaker
    • D.A. Kass, E.P. Shapiro, M. Kawaguchi Improved arterial compliance by a novel advanced glycation end-product crosslink breaker Circulation 104 2001 1464 1470
    • (2001) Circulation , vol.104 , pp. 1464-1470
    • Kass, D.A.1    Shapiro, E.P.2    Kawaguchi, M.3
  • 69
    • 3142775652 scopus 로고    scopus 로고
    • Crosslink breakers: A new approach to cardiovascular therapy
    • D. Susic, J. Varagic, J. Ahn Crosslink breakers A new approach to cardiovascular therapy Curr Opin Cardiol 19 2004 336 340
    • (2004) Curr Opin Cardiol , vol.19 , pp. 336-340
    • Susic, D.1    Varagic, J.2    Ahn, J.3
  • 70
    • 0041358574 scopus 로고    scopus 로고
    • A novel potential therapy for diabetic nephropathy and vascular complications: Protein kinase C beta inhibition
    • K.R. Tuttle, P.W. Anderson A novel potential therapy for diabetic nephropathy and vascular complications Protein kinase C beta inhibition Am J Kidney Dis 42 2003 456 465
    • (2003) Am J Kidney Dis , vol.42 , pp. 456-465
    • Tuttle, K.R.1    Anderson, P.W.2
  • 71
    • 0024563795 scopus 로고
    • Protein kinase C is activated in glomeruli from streptozotocin diabetic rats: Possible mediation by glucose
    • P.A. Craven, F.R. DeRubertis Protein kinase C is activated in glomeruli from streptozotocin diabetic rats Possible mediation by glucose J Clin Invest 83 1989 1667 1675
    • (1989) J Clin Invest , vol.83 , pp. 1667-1675
    • Craven, P.A.1    Derubertis, F.R.2
  • 72
    • 0025990146 scopus 로고
    • High glucose increases diacylglycerol mass and activates protein kinase C in mesangial cell cultures
    • S.H. Ayo, R. Radnik, J.A. Garoni High glucose increases diacylglycerol mass and activates protein kinase C in mesangial cell cultures Am J Physiol 261 1991 F571 F577
    • (1991) Am J Physiol , vol.261
    • Ayo, S.H.1    Radnik, R.2    Garoni, J.A.3
  • 73
    • 0028105717 scopus 로고
    • Activation of protein kinase C in glomerular cells in diabetes: Mechanisms and potential links to the pathogenesis of diabetic glomerulopathy
    • F.R. DeRubertis, P.A. Craven Activation of protein kinase C in glomerular cells in diabetes Mechanisms and potential links to the pathogenesis of diabetic glomerulopathy Diabetes 43 1994 1 8
    • (1994) Diabetes , vol.43 , pp. 1-8
    • Derubertis, F.R.1    Craven, P.A.2
  • 74
    • 18144447696 scopus 로고    scopus 로고
    • Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: Role of vascular NAD(P)H oxidase
    • T. Inoguchi, T. Sonta, H. Tsubouchi Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes Role of vascular NAD(P)H oxidase J Am Soc Nephrol 14 suppl 2003 S227 S232
    • (2003) J Am Soc Nephrol , vol.14 , Issue.SUPPL.
    • Inoguchi, T.1    Sonta, T.2    Tsubouchi, H.3
  • 75
    • 16844369727 scopus 로고    scopus 로고
    • Amino acids injure mesangial cells by advanced glycation end products, oxidative stress, and protein kinase C
    • K.R. Tuttle, E.C. Johnson, S.K. Cooney Amino acids injure mesangial cells by advanced glycation end products, oxidative stress, and protein kinase C Kidney Int 67 2005 953 968
    • (2005) Kidney Int , vol.67 , pp. 953-968
    • Tuttle, K.R.1    Johnson, E.C.2    Cooney, S.K.3
  • 76
    • 0026489335 scopus 로고
    • Preferential elevation of protein kinase C isoform βiI and diacylglycerol levels in the aorta and heart of diabetic rats: Differential reversibility to glycemic control by islet cell transplantation
    • T. Inoguchi, R. Battan, E. Handler Preferential elevation of protein kinase C isoform βII and diacylglycerol levels in the aorta and heart of diabetic rats Differential reversibility to glycemic control by islet cell transplantation Proc Natl Acad Sci USA 89 1992 11059 11063
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11059-11063
    • Inoguchi, T.1    Battan, R.2    Handler, E.3
  • 77
    • 0027454103 scopus 로고
    • Correlation of diacylglycerol level and protein kinase C activity in rat retinal circulation
    • T. Shiba, T. Inoguchi, J.R. Sportsman Correlation of diacylglycerol level and protein kinase C activity in rat retinal circulation Am J Physiol 265 1993 E783 E793
    • (1993) Am J Physiol , vol.265
    • Shiba, T.1    Inoguchi, T.2    Sportsman, J.R.3
  • 78
    • 13344293711 scopus 로고    scopus 로고
    • Amelioration of vascular dysfunctions in diabetic rats by an oral PKC β inhibitor
    • H. Ishii, M.R. Jirousek, D. Koya Amelioration of vascular dysfunctions in diabetic rats by an oral PKC β inhibitor Science 272 1996 728 731
    • (1996) Science , vol.272 , pp. 728-731
    • Ishii, H.1    Jirousek, M.R.2    Koya, D.3
  • 79
    • 8944246315 scopus 로고    scopus 로고
    • (S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H,13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]-oxadiazacyclohexadecene- 1,3(2H)-dione(ruboxistaurin) and related analogues: Isozyme selective inhibitors of protein kinase Cβ
    • M.R. Jirousek, J.R. Gillig, C.M. Gonzalez (S)-13-[(dimethylamino)methyl]- 10,11,14,15-tetrahydro-4,9:16,21-dimetheno-1H,13H-dibenzo[e,k]pyrrolo[3,4-h][1, 4,13]-oxadiazacyclohexadecene-1,3(2H)-dione(ruboxistaurin) and related analogues Isozyme selective inhibitors of protein kinase Cβ J Med Chem 39 1996 2664 2671
    • (1996) J Med Chem , vol.39 , pp. 2664-2671
    • Jirousek, M.R.1    Gillig, J.R.2    Gonzalez, C.M.3
  • 80
    • 0030760729 scopus 로고    scopus 로고
    • Characterization of protein kinase C β isoform activation on the gene expression of transforming growth factor-β, extracellular matrix components and prostanoids in the glomeruli of diabetic rats
    • D. Koya, M.R. Jirousek, Y.-W. Lin Characterization of protein kinase C β isoform activation on the gene expression of transforming growth factor-β, extracellular matrix components and prostanoids in the glomeruli of diabetic rats J Clin Invest 100 1997 115 126
    • (1997) J Clin Invest , vol.100 , pp. 115-126
    • Koya, D.1    Jirousek, M.R.2    Lin, Y.-W.3
  • 81
    • 0034053336 scopus 로고    scopus 로고
    • Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes
    • D. Koya, M. Haneda, H. Nakagawa Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes FASEB J 14 2000 439 447
    • (2000) FASEB J , vol.14 , pp. 439-447
    • Koya, D.1    Haneda, M.2    Nakagawa, H.3
  • 82
    • 0037315791 scopus 로고    scopus 로고
    • PKC β inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension
    • D.J. Kelly, Y. Zhang, C. Hepper PKC β inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension Diabetes 52 2003 512 518
    • (2003) Diabetes , vol.52 , pp. 512-518
    • Kelly, D.J.1    Zhang, Y.2    Hepper, C.3
  • 83
    • 0033996388 scopus 로고    scopus 로고
    • AGEs induce oxidative stress and activate protein kinase C-bII in neonatal mesangial cells
    • V. Scivittaro, M.B. Ganz, M.F. Weiss AGEs induce oxidative stress and activate protein kinase C-bII in neonatal mesangial cells Am J Physiol Renal Physiol 278 2000 F676 F683
    • (2000) Am J Physiol Renal Physiol , vol.278
    • Scivittaro, V.1    Ganz, M.B.2    Weiss, M.F.3
  • 84
    • 0036086641 scopus 로고    scopus 로고
    • Mesangial cell protein kinase C isozyme activation in the diabetic milieu
    • C.I. Whiteside, J.A. Dlugosz Mesangial cell protein kinase C isozyme activation in the diabetic milieu Am J Physiol Renal Physiol 282 2002 F975 F980
    • (2002) Am J Physiol Renal Physiol , vol.282
    • Whiteside, C.I.1    Dlugosz, J.A.2
  • 85
    • 0141755311 scopus 로고    scopus 로고
    • Translocation of glomerular p47phox and p67phox by protein kinase C-β activation is required for oxidative stress in diabetic nephropathy
    • M. Kitada, D. Koya, T. Sugimoto Translocation of glomerular p47phox and p67phox by protein kinase C-β activation is required for oxidative stress in diabetic nephropathy Diabetes 52 2003 2603 2614
    • (2003) Diabetes , vol.52 , pp. 2603-2614
    • Kitada, M.1    Koya, D.2    Sugimoto, T.3
  • 86
    • 0035430525 scopus 로고    scopus 로고
    • Angiotensin II promotes glucose-induced activation of cardiac protein kinase C isozymes and phosphorylation of troponin I
    • M. Malhotra, B.P.S. Kang, S. Cheung Angiotensin II promotes glucose-induced activation of cardiac protein kinase C isozymes and phosphorylation of troponin I Diabetes 50 2001 1918 1926
    • (2001) Diabetes , vol.50 , pp. 1918-1926
    • Malhotra, M.1    Kang, B.P.S.2    Cheung, S.3
  • 87
    • 0035108843 scopus 로고    scopus 로고
    • Aminoguanidine and ramipril prevent diabetes-induced increases in protein kinase C activity in glomeruli, retina, and mesenteric artery
    • T.M. Osiicka, Y. Yu, V. Lee Aminoguanidine and ramipril prevent diabetes-induced increases in protein kinase C activity in glomeruli, retina, and mesenteric artery Clin Sci 100 2001 249 257
    • (2001) Clin Sci , vol.100 , pp. 249-257
    • Osiicka, T.M.1    Yu, Y.2    Lee, V.3
  • 88
    • 0036364543 scopus 로고    scopus 로고
    • Standards of medical care for patients with diabetes mellitus
    • American Diabetes Association
    • American Diabetes Association Standards of medical care for patients with diabetes mellitus Diabetes Care 25 2002 213 229
    • (2002) Diabetes Care , vol.25 , pp. 213-229
  • 89
    • 16844385885 scopus 로고    scopus 로고
    • K/DOQI Clinical Practice Guidelines on Hypertension and Antihypertensive Agents in Chronic Kidney Disease. Pharmacological therapy: Diabetic kidney disease
    • K/DOQI Clinical Practice Guidelines on Hypertension and Antihypertensive Agents in Chronic Kidney Disease. Pharmacological therapy diabetic kidney disease Am J Kidney Dis 43 suppl 2004 S142 S158
    • (2004) Am J Kidney Dis , vol.43 , Issue.SUPPL.


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