-
1
-
-
0021997185
-
Organ-specific autoimmune diseases induced in mice by elimination of T-cell subset. I. Evidence for the active participation of T cells in natural self-tolerance: Deficit of a T-cell subset as a possible cause of autoimmune disease
-
Sakaguchi S, Fukuma K, Kuribayashi K, Masuda T. Organ-specific autoimmune diseases induced in mice by elimination of T-cell subset. I. Evidence for the active participation of T cells in natural self-tolerance: deficit of a T-cell subset as a possible cause of autoimmune disease. J Exp Med 1985; 161: 72-87.
-
(1985)
J Exp Med
, vol.161
, pp. 72-87
-
-
Sakaguchi, S.1
Fukuma, K.2
Kuribayashi, K.3
Masuda, T.4
-
2
-
-
2442484053
-
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi S. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004; 22: 531-62.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
3
-
-
0029150110
-
Immunologic tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): Breakdown of a single mechanism of self tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): breakdown of a single mechanism of self tolerance causes various autoimmune diseases. J Immunol 1995; 155: 1151-64.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
4
-
-
0038434099
-
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
-
Gambineri E, Torgerson TR, Ochs HD. Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr Opin Rheumatol 2003; 15: 430-5.
-
(2003)
Curr Opin Rheumatol
, vol.15
, pp. 430-435
-
-
Gambineri, E.1
Torgerson, T.R.2
Ochs, H.D.3
-
5
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan MS, Boesteanu A, Reed AJ i sur. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immun 2001; 2: 301-6.
-
(2001)
Nat Immun
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
Boesteanu, A.2
Reed, A.J.3
-
6
-
-
4143066714
-
Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors
-
Hsieh CS, Liang Y, Tyznik AJ, Self SG, Liggitt D, Rudensky AY. Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors. Immunity 2004; 21: 267-77.
-
(2004)
Immunity
, vol.21
, pp. 267-277
-
-
Hsieh, C.S.1
Liang, Y.2
Tyznik, A.J.3
Self, S.G.4
Liggitt, D.5
Rudensky, A.Y.6
-
7
-
-
0030073402
-
A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens
-
Modigliani Y, Bandeira A, Coutinho A. A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens. Immunol Rev 1996; 149: 155-20.
-
(1996)
Immunol Rev
, vol.149
, pp. 155-120
-
-
Modigliani, Y.1
Bandeira, A.2
Coutinho, A.3
-
8
-
-
16844365788
-
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
-
Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immun 2005; 6: 345-52.
-
(2005)
Nat Immun
, vol.6
, pp. 345-352
-
-
Sakaguchi, S.1
-
9
-
-
17144405680
-
Potential role of interleukin-10 secreting regulatory T cells in allergy and asthma
-
Hawrylowicz CM, O'Garra A. Potential role of interleukin-10 secreting regulatory T cells in allergy and asthma. Nat Rev Immunol 2005; 5: 271-83
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 271-283
-
-
Hawrylowicz, C.M.1
O'Garra, A.2
-
11
-
-
0344585521
-
Self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cells
-
Cozzo C, Larkin J, Caton AJ. Self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cells. J Immunol 2003; 171: 5678-5682.
-
(2003)
J Immunol
, vol.171
, pp. 5678-5682
-
-
Cozzo, C.1
Larkin, J.2
Caton, A.J.3
-
12
-
-
16844369607
-
Natural regulatory T cells in infectious disease
-
Belkaid Y, Rouse BT. Natural regulatory T cells in infectious disease. Nat Immun 2005; 6: 353-60.
-
(2005)
Nat Immun
, vol.6
, pp. 353-360
-
-
Belkaid, Y.1
Rouse, B.T.2
-
13
-
-
16844362608
-
Mechanisms of suppression by suppressor T cells
-
Boehmer H. Mechanisms of suppression by suppressor T cells. Nat Immun 2005; 6: 338-44.
-
(2005)
Nat Immun
, vol.6
, pp. 338-344
-
-
Boehmer, H.1
-
14
-
-
0037018104
-
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
-
Barrat FJ, Cua DJ, Boonstra A i sur. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 2002; 195: 603-16.
-
(2002)
J Exp Med
, vol.195
, pp. 603-616
-
-
Barrat, F.J.1
Cua, D.J.2
Boonstra, A.3
-
15
-
-
8544242704
-
T cells: Friend or foe in immunity to infection?
-
Mills KH. Regulatory T cells: friend or foe in immunity to infection? Nat Rev Immunol 2004; 4: 841-55.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 841-855
-
-
Regulatory, M.K.H.1
-
16
-
-
0030704726
-
Generation of a novel regulatory CD4+ T-cell population, which inhibits antigen-specific T-cell responses
-
Groux H. Generation of a novel regulatory CD4+ T-cell population, which inhibits antigen-specific T-cell responses. Nature 1997; 389: 737-742.
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
-
17
-
-
0035339884
-
IFN-α and IL-10 induce the differentiation of human type 1 T regulatory cells
-
Levings MK, Sangregorio R, Galbiati F i sur. IFN-α and IL-10 induce the differentiation of human type 1 T regulatory cells. J Immunol 2001; 166: 5530-5539.
-
(2001)
J Immunol
, vol.166
, pp. 5530-5539
-
-
Levings, M.K.1
Sangregorio, R.2
Galbiati, F.3
-
18
-
-
0035186416
-
Induction and mechanism of action of transforming growth fartor-α-secreting Th3 regulatory cells
-
Weiner HL. Induction and mechanism of action of transforming growth fartor-α-secreting Th3 regulatory cells. Immunol Rev 2001; 182: 207-214.
-
(2001)
Immunol Rev
, vol.182
, pp. 207-214
-
-
Weiner, H.L.1
-
19
-
-
0028037782
-
Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
-
Chen Y, Kuchroo VK, Inobe J, Hafler DA, Weiner HL. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 1994; 265: 1237-40.
-
(1994)
Science
, vol.265
, pp. 1237-1240
-
-
Chen, Y.1
Kuchroo, V.K.2
Inobe, J.3
Hafler, D.A.4
Weiner, H.L.5
-
20
-
-
0037131969
-
Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells
-
Levings MK, Sangregorio R, Sartirana C i sur. Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J Exp Med 2002; 196: 1335-46.
-
(2002)
J Exp Med
, vol.196
, pp. 1335-1346
-
-
Levings, M.K.1
Sangregorio, R.2
Sartirana, C.3
-
21
-
-
85047692430
-
IL-10-producing and naturally occurring CD4+ Tregs: Limiting collateral damage
-
O'Garra A, Vieira PL, Vieira P, Goldfeld AE. IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage. J Clin Invest 2004; 114: 1372-8.
-
(2004)
J Clin Invest
, vol.114
, pp. 1372-1378
-
-
O'Garra, A.1
Vieira, P.L.2
Vieira, P.3
Goldfeld, A.E.4
-
22
-
-
0035172782
-
NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance
-
Sonoda KH, Faunce DE, Taniguchi M, Exley M, Balk S, Stein-Streilein J. NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance. J Immunol 2001; 166: 42-50.
-
(2001)
J Immunol
, vol.166
, pp. 42-50
-
-
Sonoda, K.H.1
Faunce, D.E.2
Taniguchi, M.3
Exley, M.4
Balk, S.5
Stein-Streilein, J.6
-
23
-
-
0030890603
-
Mouse CD1-specific NK1 T cells: Development, specificity and function
-
Bendelac A, Rivera MN, Park SH, Roark JH. Mouse CD1-specific NK1 T cells: development, specificity and function. Annu Rev Immunol 1997; 15: 535-62.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 535-562
-
-
Bendelac, A.1
Rivera, M.N.2
Park, S.H.3
Roark, J.H.4
-
24
-
-
0029029565
-
CD1 recognition by mouse NK1+ T lymphocytes
-
Bendelac A, Lantz O, Quimby ME, Yewdell JW, Bennink JR, Brutkiewicz RR. CD1 recognition by mouse NK1+ T lymphocytes. Science 1995; 268: 863-5.
-
(1995)
Science
, vol.268
, pp. 863-865
-
-
Bendelac, A.1
Lantz, O.2
Quimby, M.E.3
Yewdell, J.W.4
Bennink, J.R.5
Brutkiewicz, R.R.6
-
25
-
-
0036268008
-
Regulatory natural killer T cells protect against spontaneous and recurrent type 1 diabetes
-
Sharif S, Arreaza GA, Zucker P, Delovitch TL. Regulatory natural killer T cells protect against spontaneous and recurrent type 1 diabetes. Ann N Y Acad Sci 2002; 958: 77-88.
-
(2002)
Ann N Y Acad Sci
, vol.958
, pp. 77-88
-
-
Sharif, S.1
Arreaza, G.A.2
Zucker, P.3
Delovitch, T.L.4
-
26
-
-
0032030582
-
A novel role for TGF-beta and IL-10 in the induction of immune privilege
-
D'Orazio TJ, Niederkorn JY. A novel role for TGF-beta and IL-10 in the induction of immune privilege. J Immunol 1998; 160: 2089-98.
-
(1998)
J Immunol
, vol.160
, pp. 2089-2098
-
-
D'Orazio, T.J.1
Niederkorn, J.Y.2
-
27
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+ CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
Takahashi T, Kuniyasu Y, Toda M i sur. Immunologic self-tolerance maintained by CD25+ CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 1998; 10: 1969-80.
-
(1998)
Int Immunol
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
-
28
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton AM, Shevach EM. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998; 188: 287-96.
-
(1998)
J Exp Med
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
29
-
-
3142708571
-
Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
-
Paust S, Lu L, McCarty N, Cantor H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci U S A 2004; 101: 10398-403.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10398-10403
-
-
Paust, S.1
Lu, L.2
McCarty, N.3
Cantor, H.4
-
30
-
-
5044220930
-
IDO expression by dendritic cells: Tolerance and tryptophan catabolism
-
Mellor AL, Munn DH. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 2004; 4: 762-74.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 762-774
-
-
Mellor, A.L.1
Munn, D.H.2
-
31
-
-
0036597371
-
CD4+ CD25+ suppressor T cells: More questions than answers
-
Shevach EM. CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol 2002; 2: 389-400.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 389-400
-
-
Shevach, E.M.1
-
32
-
-
0036086232
-
Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells
-
Taams LS, Vukmanovic-Stejic M, Smith J i sur. Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells. Eur J Immunol 2002; 32: 1621-30.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1621-1630
-
-
Taams, L.S.1
Vukmanovic-Stejic, M.2
Smith, J.3
-
33
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299: 1057-61.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
34
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immun 2003; 4: 330-6.
-
(2003)
Nat Immun
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
35
-
-
17044393922
-
Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells
-
Bettelli E, Dastrange M, Oukka M. Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A 2005; 102: 5138-43.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 5138-5143
-
-
Bettelli, E.1
Dastrange, M.2
Oukka, M.3
-
36
-
-
0036379775
-
X-chromosome inactivarion analysis in a female carrier of FOXP3 mutation
-
Tommasini A, Ferrari S, Moratto D i sur. X-chromosome inactivarion analysis in a female carrier of FOXP3 mutation. Clin Exp Immunol 2002; 130: 127-30.
-
(2002)
Clin Exp Immunol
, vol.130
, pp. 127-130
-
-
Tommasini, A.1
Ferrari, S.2
Moratto, D.3
-
37
-
-
0028484545
-
CTLA-4 can function as a negative regulator of T cell activation
-
Walunas TL, Lenschow DJ, Bakker CY i sur. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1994; 1: 405-413.
-
(1994)
Immunity
, vol.1
, pp. 405-413
-
-
Walunas, T.L.1
Lenschow, D.J.2
Bakker, C.Y.3
-
38
-
-
33845979040
-
-
New York: 6th edition. Garland Science Publishing
-
Bour-Jordan H, Bluestone JA. T-cell mediated immunity U: Janeway CA, Travers P, Walport M, Shlomchik MJ, Immunobiology - the immune system in health and disease. New York: 6th edition. Garland Science Publishing, 2005, 328-31.
-
(2005)
T-cell mediated immunity U: Janeway CA, Travers P, Walport M, Shlomchik MJ, Immunobiology - the immune system in health and disease
, pp. 328-331
-
-
Bour-Jordan, H.1
Bluestone, J.A.2
-
39
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4
-
Waterhouse P, Penninger JM, Timms E i sur. Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science 1995; 270: 985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
-
40
-
-
1642338649
-
Cloning and characterization of GITR ligand
-
Kim JD, Choi BK, Bae JS i sur. Cloning and characterization of GITR ligand. Genes Immun 2003; 4: 564-9.
-
(2003)
Genes Immun
, vol.4
, pp. 564-569
-
-
Kim, J.D.1
Choi, B.K.2
Bae, J.S.3
-
41
-
-
6344279933
-
Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells
-
Stephens GL, McHugh RS, Whitters MJ i sur. Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells. J Immunol 2004; 173: 5008-20.
-
(2004)
J Immunol
, vol.173
, pp. 5008-5020
-
-
Stephens, G.L.1
McHugh, R.S.2
Whitters, M.J.3
-
42
-
-
0036144888
-
Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo
-
Gavin MA, Clarke SR, Negrou E, Gallegos A, Rudensky A. Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo. Nat Immun 2002; 3: 33-41.
-
(2002)
Nat Immun
, vol.3
, pp. 33-41
-
-
Gavin, M.A.1
Clarke, S.R.2
Negrou, E.3
Gallegos, A.4
Rudensky, A.5
-
43
-
-
0036170938
-
Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance
-
Shimizu J, Yamazaki S, Takahashi T, Ishida Y, Sakaguchi S. Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance. Nat Immun 2002; 3: 135-42.
-
(2002)
Nat Immun
, vol.3
, pp. 135-142
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
44
-
-
0036195161
-
CD4+CD25+ immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
McHugh RS, Whitters MJ, Piccirillo CA i sur. CD4+CD25+ immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 2002; 16: 311-23.
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.S.1
Whitters, M.J.2
Piccirillo, C.A.3
-
45
-
-
2442429448
-
Cutting edge: The natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression
-
Ji HB, Liao G, Faubion WA, Abadia-Molina AC i sur. Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression. J Immunol 2004; 172: 5823-7.
-
(2004)
J Immunol
, vol.172
, pp. 5823-5827
-
-
Ji, H.B.1
Liao, G.2
Faubion, W.A.3
Abadia-Molina, A.C.4
-
46
-
-
17444414236
-
GITR: A multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily
-
Nocentini G, Riccardi C. GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily. Eur J Immunol 2005; 35: 1016-22.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1016-1022
-
-
Nocentini, G.1
Riccardi, C.2
-
47
-
-
0345598872
-
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is co-stimulatory for T cells
-
Tone M, Tone Y, Adams E i sur. Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is co-stimulatory for T cells. Proc Natl Acad Sci. U S A 2003; 100: 15059-15064.
-
(2003)
Proc Natl Acad Sci. U S A
, vol.100
, pp. 15059-15064
-
-
Tone, M.1
Tone, Y.2
Adams, E.3
-
48
-
-
0141570624
-
Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells
-
Yu KY, Kim HS, Song SY, Min SS, Jeong JJ, Youn BS. Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells. Biochem Biophys Res Commun 2003; 310: 433-438.
-
(2003)
Biochem Biophys Res Commun
, vol.310
, pp. 433-438
-
-
Yu, K.Y.1
Kim, H.S.2
Song, S.Y.3
Min, S.S.4
Jeong, J.J.5
Youn, B.S.6
-
49
-
-
0036888554
-
New regulatory coreceptors: Inducible co-stimulator and PD-1
-
Okazaki T, Iwai Y, Honjo T. New regulatory coreceptors: inducible co-stimulator and PD-1. Curr Opin Immunol 2002; 14: 779-82.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 779-782
-
-
Okazaki, T.1
Iwai, Y.2
Honjo, T.3
-
50
-
-
10744222828
-
Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes
-
Anastasi E, Campese AF, Bellavia D i sur. Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes. J Immunol 2003; 171: 4504-11.
-
(2003)
J Immunol
, vol.171
, pp. 4504-4511
-
-
Anastasi, E.1
Campese, A.F.2
Bellavia, D.3
-
51
-
-
0026700235
-
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
-
Ishida Y, Agata Y, Shibahara K, Honjo T. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 1992; 11: 3887-95.
-
(1992)
EMBO J
, vol.11
, pp. 3887-3895
-
-
Ishida, Y.1
Agata, Y.2
Shibahara, K.3
Honjo, T.4
-
52
-
-
0030005099
-
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
-
Agata Y, Kawasaki A, Nishimura H i sur. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol 1996; 8: 765.
-
(1996)
Int Immunol
, vol.8
, pp. 765
-
-
Agata, Y.1
Kawasaki, A.2
Nishimura, H.3
-
53
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y i sur. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000; 192: 1027.
-
(2000)
J Exp Med
, vol.192
, pp. 1027
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
-
54
-
-
0037438490
-
Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: Attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses
-
Bennett F, Luxenberg D, Ling V i sur. Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses. J Immunol 2003; 170: 711-8.
-
(2003)
J Immunol
, vol.170
, pp. 711-718
-
-
Bennett, F.1
Luxenberg, D.2
Ling, V.3
-
55
-
-
33845983209
-
Signaling through immune system receptors. U: Janeway CA, Travers P, Walport M, Shlomchik MJ
-
6th edition. New York: Garland Science Publishing
-
Anderson G, Moore NC, Owen JJT, Jenkinson EJ. Signaling through immune system receptors. U: Janeway CA, Travers P, Walport M, Shlomchik MJ. Immunobiology - the immune system in health and disease. 6th edition. New York: Garland Science Publishing, 2005, 251-2.
-
(2005)
Immunobiology - the immune system in health and disease
, pp. 251-252
-
-
Anderson, G.1
Moore, N.C.2
Owen, J.J.T.3
Jenkinson, E.J.4
-
56
-
-
0242493801
-
Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells
-
Yvon ES, Vigouroux S, Rousseau RF i sur. Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells. Blood 2003; 102: 3815-21.
-
(2003)
Blood
, vol.102
, pp. 3815-3821
-
-
Yvon, E.S.1
Vigouroux, S.2
Rousseau, R.F.3
-
57
-
-
5644302161
-
Human T regulatory cells can use the perform pathway to cause autologous target cell death
-
Grossman WJ, Verbsky JW, Barchet W, Colonna M, Atkinson JP, Ley TJ. Human T regulatory cells can use the perform pathway to cause autologous target cell death. Immunity 2004; 21: 589-601.
-
(2004)
Immunity
, vol.21
, pp. 589-601
-
-
Grossman, W.J.1
Verbsky, J.W.2
Barchet, W.3
Colonna, M.4
Atkinson, J.P.5
Ley, T.J.6
-
58
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett CL, Christie J, Ramsdell F i sur. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001; 27: 20-1.
-
(2001)
Nat Genet
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
-
59
-
-
3543140687
-
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy
-
Ehrenstein MR, Evans JG, Singh A i sur. Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy. J Exp Med 2004; 200: 277-85.
-
(2004)
J Exp Med
, vol.200
, pp. 277-285
-
-
Ehrenstein, M.R.1
Evans, J.G.2
Singh, A.3
-
60
-
-
1842732224
-
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
-
Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med 2004; 199: 971-9.
-
(2004)
J Exp Med
, vol.199
, pp. 971-979
-
-
Viglietta, V.1
Baecher-Allan, C.2
Weiner, H.L.3
Hafler, D.A.4
-
61
-
-
12144249838
-
Defective suppressor function in CD4+CD25+ T-cells from patients with type 1 diabetes
-
Lindley S, Dayan CM, Bishop A, Roep BO, Peakman M, Tree TI. Defective suppressor function in CD4+CD25+ T-cells from patients with type 1 diabetes. Diabetes 2005; 54: 92-9.
-
(2005)
Diabetes
, vol.54
, pp. 92-99
-
-
Lindley, S.1
Dayan, C.M.2
Bishop, A.3
Roep, B.O.4
Peakman, M.5
Tree, T.I.6
-
62
-
-
1342308180
-
Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease
-
Ling EM, Smith T, Nguyen XD i sur. Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease. Lancet 2004; 363: 608-15.
-
(2004)
Lancet
, vol.363
, pp. 608-615
-
-
Ling, E.M.1
Smith, T.2
Nguyen, X.D.3
-
63
-
-
0345016451
-
Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals
-
Cavani A, Nasorri F, Ottaviani C, Sebastiani S, De Pita O, Girolomoni G. Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals. J Immunol 2003; 171: 5760-8.
-
(2003)
J Immunol
, vol.171
, pp. 5760-5768
-
-
Cavani, A.1
Nasorri, F.2
Ottaviani, C.3
Sebastiani, S.4
De Pita, O.5
Girolomoni, G.6
-
64
-
-
1642453571
-
Ultraviolet light-induced regulatory (suppressor) T cells: An approach for promoting induction of operational allograft tolerance?
-
Aubin F, Mousson C. Ultraviolet light-induced regulatory (suppressor) T cells: an approach for promoting induction of operational allograft tolerance? Transplantation 2004; 77 (1 Suppl): S29-31.
-
(2004)
Transplantation
, vol.77
, Issue.1 SUPPL.
-
-
Aubin, F.1
Mousson, C.2
-
65
-
-
3042594506
-
Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy
-
Karlsson MR, Rugtveit J, Brandtzaeg P. Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy. J Exp Med 2004; 199: 1679-88.
-
(2004)
J Exp Med
, vol.199
, pp. 1679-1688
-
-
Karlsson, M.R.1
Rugtveit, J.2
Brandtzaeg, P.3
-
66
-
-
0037086525
-
CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons
-
MacDonald AJ, Duffy M, Brady MT i sur. CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons. J Infect Dis 2002; 185: 720-727.
-
(2002)
J Infect Dis
, vol.185
, pp. 720-727
-
-
MacDonald, A.J.1
Duffy, M.2
Brady, M.T.3
-
67
-
-
0347382454
-
Hepatitis C virus non-structural protein 4 suppresses TH1 responses by stimulating IL-10 production from monocytes
-
Brady MT, MacDonald AJ, Rowan AG, Mills KH. Hepatitis C virus non-structural protein 4 suppresses TH1 responses by stimulating IL-10 production from monocytes. Eur J Immunol 2003; 33: 3448-3457.
-
(2003)
Eur J Immunol
, vol.33
, pp. 3448-3457
-
-
Brady, M.T.1
MacDonald, A.J.2
Rowan, A.G.3
Mills, K.H.4
-
68
-
-
0035873382
-
IL-10-deficient mice demonstrate multiple organ failure and increased mortality during Escherichia coli peritonitis despite an accelerated bacterial clearance
-
Sewnath ME, Olszyna DP, Birjmohun R, ten Kate FJ, Gouma DJ, van Der Poll T. IL-10-deficient mice demonstrate multiple organ failure and increased mortality during Escherichia coli peritonitis despite an accelerated bacterial clearance. J Immunol 2001; 166: 6323-6331.
-
(2001)
J Immunol
, vol.166
, pp. 6323-6331
-
-
Sewnath, M.E.1
Olszyna, D.P.2
Birjmohun, R.3
ten Kate, F.J.4
Gouma, D.J.5
van Der Poll, T.6
-
69
-
-
0042333419
-
Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology
-
Higgins SC, Lavelle EC, McCann C i sur. Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology. J Immunol 2003; 171; 3119-3127.
-
(2003)
J Immunol
, vol.171
, pp. 3119-3127
-
-
Higgins, S.C.1
Lavelle, E.C.2
McCann, C.3
-
70
-
-
0036107373
-
CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice
-
Hori S, Carvalho TL, Demengeot J. CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice. Eur J Immunol 2002; 32; 1282-1291.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1282-1291
-
-
Hori, S.1
Carvalho, T.L.2
Demengeot, J.3
-
71
-
-
0036884607
-
B7/CD28-dependent CD4+CD25+ regulatory T cells are essential components of the memory-protective immunity to Candida albicans
-
Montagnoli C, Bacci A, Bozza S i sur.. B7/CD28-dependent CD4+CD25+ regulatory T cells are essential components of the memory-protective immunity to Candida albicans. J Immunol 2002; 169: 6298-6308.
-
(2002)
J Immunol
, vol.169
, pp. 6298-6308
-
-
Montagnoli, C.1
Bacci, A.2
Bozza, S.3
-
72
-
-
1542409922
-
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells
-
Netea MG, Sutmuller R, Hermann C i sur. Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells. J Immunol 2004; 172: 3712-3718.
-
(2004)
J Immunol
, vol.172
, pp. 3712-3718
-
-
Netea, M.G.1
Sutmuller, R.2
Hermann, C.3
-
73
-
-
1342324588
-
The pathogenesis of schistosomiasis is controlled by cooperating IL-10 producing innate effector and regulatory T cells
-
Hesse M, Piccirillo CA, Belkaid Y i sur. The pathogenesis of schistosomiasis is controlled by cooperating IL-10 producing innate effector and regulatory T cells. J Immunol 2004; 172: 3157-3166.
-
(2004)
J Immunol
, vol.172
, pp. 3157-3166
-
-
Hesse, M.1
Piccirillo, C.A.2
Belkaid, Y.3
-
74
-
-
0035252656
-
Hijacking and exploitation of IL-10 by intracellular pathogens
-
Redpath S, Ghazal P, Gascoigne NR. Hijacking and exploitation of IL-10 by intracellular pathogens. Trends Microbiol 2001; 9: 86-92.
-
(2001)
Trends Microbiol
, vol.9
, pp. 86-92
-
-
Redpath, S.1
Ghazal, P.2
Gascoigne, N.R.3
-
75
-
-
0036717722
-
Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases
-
McGuirk P, Mills KH. Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases. Trends Immunol 2002; 23: 450-5.
-
(2002)
Trends Immunol
, vol.23
, pp. 450-455
-
-
McGuirk, P.1
Mills, K.H.2
-
76
-
-
0038280092
-
Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1
-
Marshall NA, Vickers MA, Barker RN. Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1. J Immunol 2003; 170: 6183-6189.
-
(2003)
J Immunol
, vol.170
, pp. 6183-6189
-
-
Marshall, N.A.1
Vickers, M.A.2
Barker, R.N.3
-
77
-
-
12944310982
-
IL-10-producing T cells suppress immune responses in anergic tuberculosis patients
-
Boussiotis VA, Tsai EY, Yunis EJ i sur. IL-10-producing T cells suppress immune responses in anergic tuberculosis patients. J Clin Invest 2000; 105: 1317-1325.
-
(2000)
J Clin Invest
, vol.105
, pp. 1317-1325
-
-
Boussiotis, V.A.1
Tsai, E.Y.2
Yunis, E.J.3
-
78
-
-
2242423605
-
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
-
Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 2002; 420: 502-507.
-
(2002)
Nature
, vol.420
, pp. 502-507
-
-
Belkaid, Y.1
Piccirillo, C.A.2
Mendez, S.3
Shevach, E.M.4
Sacks, D.L.5
-
79
-
-
0035890108
-
Quantitative and qualitative assessment of human immunodeficiency virus type 1 (HIV-1) - specific CD4+ T cell immunity to gag in HTV-1 infected individuals with differential disease progression: Reciprocal interferon-γ and interleukin-10 responses
-
Ostrowski MA, Gu JX, Kovacs C, Freedman J, Luscher MA, MacDonald KS. Quantitative and qualitative assessment of human immunodeficiency virus type 1 (HIV-1) - specific CD4+ T cell immunity to gag in HTV-1 infected individuals with differential disease progression: reciprocal interferon-γ and interleukin-10 responses. J Infect Dis 2001; 184: 1268-1278.
-
(2001)
J Infect Dis
, vol.184
, pp. 1268-1278
-
-
Ostrowski, M.A.1
Gu, J.X.2
Kovacs, C.3
Freedman, J.4
Luscher, M.A.5
MacDonald, K.S.6
-
80
-
-
3543098686
-
CD25+CD4+ regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4+ and CD8+ HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status
-
Kinter AL, Hennessey M, Bell A i sur. CD25+CD4+ regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4+ and CD8+ HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J Exp Med 2004; 200: 331-343.
-
(2004)
J Exp Med
, vol.200
, pp. 331-343
-
-
Kinter, A.L.1
Hennessey, M.2
Bell, A.3
-
81
-
-
10744227590
-
Human CD4+CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens
-
Aandahl EM, Michaelsson J, Moretto WJ, Hecht FM, Nixon DF. Human CD4+CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. J Virol 2004; 78: 2454-2459.
-
(2004)
J Virol
, vol.78
, pp. 2454-2459
-
-
Aandahl, E.M.1
Michaelsson, J.2
Moretto, W.J.3
Hecht, F.M.4
Nixon, D.F.5
-
82
-
-
11944260595
-
CD4+CD25+ regulatory T cells: II. Origin, disease models and clinical aspects
-
Nielsen J, Holm TL, Claesson MH. CD4+CD25+ regulatory T cells: II. Origin, disease models and clinical aspects. APMIS 2004; 112: 642-50.
-
(2004)
APMIS
, vol.112
, pp. 642-650
-
-
Nielsen, J.1
Holm, T.L.2
Claesson, M.H.3
-
83
-
-
0033571105
-
Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity
-
Shimizu J, Yamazaki S, Sakaguchi S. Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol 1999; 163: 5211-8.
-
(1999)
J Immunol
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
Yamazaki, S.2
Sakaguchi, S.3
-
84
-
-
0035903324
-
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25+ regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
-
Sutmuller RP, van Duivenvoorde LM, van Elsas A i sur. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25+ regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 2001; 194: 823-32.
-
(2001)
J Exp Med
, vol.194
, pp. 823-832
-
-
Sutmuller, R.P.1
van Duivenvoorde, L.M.2
van Elsas, A.3
-
85
-
-
20444497416
-
The number of human peripheral blood CD4+ CD25 high regulatory T cells increases with age
-
Gregg R, Smith CM, Clark FJ i sur. The number of human peripheral blood CD4+ CD25 high regulatory T cells increases with age. Clin Exp Immunol 2005; 140: 540-6.
-
(2005)
Clin Exp Immunol
, vol.140
, pp. 540-546
-
-
Gregg, R.1
Smith, C.M.2
Clark, F.J.3
-
86
-
-
17144374934
-
Regulatory T-cell therapy: Is it ready for the clinic?
-
Bluestone JA. Regulatory T-cell therapy: is it ready for the clinic? Nat Rev Immunol 2005; 5: 343-9.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 343-349
-
-
Bluestone, J.A.1
-
87
-
-
0035806323
-
Human CD25+CD4+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
-
Levings MK, Sangregorio R, Roncarolo MG. Human CD25+CD4+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J Exp Med 2001; 193: 1295-302.
-
(2001)
J Exp Med
, vol.193
, pp. 1295-1302
-
-
Levings, M.K.1
Sangregorio, R.2
Roncarolo, M.G.3
-
88
-
-
0043244867
-
Antigen-dependent proliferation of CD44+ CD25+ regulatory T cells in vivo
-
Walker LS, Chodos A, Eggena M, Dooms H, Abbas AK. Antigen-dependent proliferation of CD44+ CD25+ regulatory T cells in vivo. J Exp Med 2003; 198: 249-58.
-
(2003)
J Exp Med
, vol.198
, pp. 249-258
-
-
Walker, L.S.1
Chodos, A.2
Eggena, M.3
Dooms, H.4
Abbas, A.K.5
-
89
-
-
20844432359
-
Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma
-
Karagiannidis C, Akdis M, Holopainen P i sur. Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. J Allergy Clin Immunol 2004; 114: 1425-33.
-
(2004)
J Allergy Clin Immunol
, vol.114
, pp. 1425-1433
-
-
Karagiannidis, C.1
Akdis, M.2
Holopainen, P.3
|