-
1
-
-
0036830474
-
Mitochondrial function and dysfunction in the cell: Its relevance to aging and aging-related disease
-
Nicholls DG. Mitochondrial function and dysfunction in the cell: Its relevance to aging and aging-related disease. Intl J Biochem Cell Biol 2002;34:1372-81
-
(2002)
Intl J Biochem Cell Biol
, vol.34
, pp. 1372-1381
-
-
Nicholls, D.G.1
-
2
-
-
0032125488
-
Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis
-
Martin LJ, Al-Abdulla NA, Brambrink AM, et al. Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis. Brain Res Bull 1998;46:281-309
-
(1998)
Brain Res Bull
, vol.46
, pp. 281-309
-
-
Martin, L.J.1
Al-Abdulla, N.A.2
Brambrink, A.M.3
-
3
-
-
13944261588
-
Cellular defences destroyed
-
Choi DW. Cellular defences destroyed. Nature 2005;433:696-98
-
(2005)
Nature
, vol.433
, pp. 696-698
-
-
Choi, D.W.1
-
4
-
-
0014668762
-
Brain lesion, obesity, and other disturbances in mice treated with monosodium glutamate
-
Olney JW. Brain lesion, obesity, and other disturbances in mice treated with monosodium glutamate. Science 1969;164:366-68
-
(1969)
Science
, vol.164
, pp. 366-368
-
-
Olney, J.W.1
-
5
-
-
33744964144
-
Synaptic mitochondria are more susceptible to Ca2+ overload than nonsynaptic mitochondria
-
Brown MR, Sullivan PG, Geddes JW. Synaptic mitochondria are more susceptible to Ca2+ overload than nonsynaptic mitochondria. J Biol Chem 2006;281:11658-68
-
(2006)
J Biol Chem
, vol.281
, pp. 11658-11668
-
-
Brown, M.R.1
Sullivan, P.G.2
Geddes, J.W.3
-
6
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn of evolutionary medicine
-
Wallace DC. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn of evolutionary medicine. Annu Rev Genet 2005;39:359-407
-
(2005)
Annu Rev Genet
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
7
-
-
0027293275
-
ALS, SOD and peroxynitrite
-
Beckman JS, Carson M, Smith CD, Koppenol WH. ALS, SOD and peroxynitrite. Nature 1993;364:548
-
(1993)
Nature
, vol.364
, pp. 548
-
-
Beckman, J.S.1
Carson, M.2
Smith, C.D.3
Koppenol, W.H.4
-
8
-
-
0036807332
-
DNA damage profiling in motor neurons: A single-cell analysis by comet assay
-
Martin LJ, Liu Z. DNA damage profiling in motor neurons: A single-cell analysis by comet assay. Neurochem Res 2002;27:1089-100
-
(2002)
Neurochem Res
, vol.27
, pp. 1089-1100
-
-
Martin, L.J.1
Liu, Z.2
-
9
-
-
0036311492
-
On the origin, evolution, and nature of programmed cell death: A timeline of four billion years
-
Ameisen JC. On the origin, evolution, and nature of programmed cell death: A timeline of four billion years. Cell Death Diff 2002;9:367-93
-
(2002)
Cell Death Diff
, vol.9
, pp. 367-393
-
-
Ameisen, J.C.1
-
10
-
-
0031057656
-
Bcl-2 gene family in the nervous system
-
Merry DE, Korsmeyer SJ. Bcl-2 gene family in the nervous system. Ann Rev Neurosci 1997;20:245-67
-
(1997)
Ann Rev Neurosci
, vol.20
, pp. 245-267
-
-
Merry, D.E.1
Korsmeyer, S.J.2
-
11
-
-
0036716281
-
The bcl-2 family: Regulators of the cellular life-or-death switch
-
Cory S, Adams JM. The bcl-2 family: Regulators of the cellular life-or-death switch. Nat Rev 2002;2:647-56
-
(2002)
Nat Rev
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
12
-
-
1642491755
-
Mitochondrial effectors in caspase-independent cell death
-
Lorenzo HK, Susin SA. Mitochondrial effectors in caspase-independent cell death. FEBS Lett 2004;557:14-20
-
(2004)
FEBS Lett
, vol.557
, pp. 14-20
-
-
Lorenzo, H.K.1
Susin, S.A.2
-
13
-
-
9844257587
-
Inhibition of bax channel-forming activity by bcl-2
-
Antonsson B, Conti F, Ciavatta A, et al. Inhibition of bax channel-forming activity by bcl-2. Science 1997;277:370-72
-
(1997)
Science
, vol.277
, pp. 370-372
-
-
Antonsson, B.1
Conti, F.2
Ciavatta, A.3
-
14
-
-
0032566649
-
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
-
Marzo I, Brenner C, Zamzami N, et al. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 1998;281:2027-31
-
(1998)
Science
, vol.281
, pp. 2027-2031
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
-
15
-
-
0034697365
-
Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c
-
Shimizu S, Ide T, Yanagida T, Tsujimoto Y. Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c. J Biol Chem 2000;275:12321-25
-
(2000)
J Biol Chem
, vol.275
, pp. 12321-12325
-
-
Shimizu, S.1
Ide, T.2
Yanagida, T.3
Tsujimoto, Y.4
-
16
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: A primary site for bcl-2 regulation of apoptosis. Science 1997;275:1132-36
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
17
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin SA, Lorenzo HK, Zamzami N, et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999;397:441-46
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
-
18
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-89
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
-
19
-
-
0030613796
-
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
-
Vander Heiden MG, Chandel NS, Williamson EK, et al. Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 1997;91:627-37
-
(1997)
Cell
, vol.91
, pp. 627-637
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
-
20
-
-
0035957653
-
Proapoptotic Bax and Bak: A requisite gateway to mitochondrial dysfunction and death
-
Wei MC, Zong W-X, Cheng EH-Y, et al. Proapoptotic Bax and Bak: A requisite gateway to mitochondrial dysfunction and death. Science 2001;292:727-30
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.-X.2
Cheng, E.H.-Y.3
-
21
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A, Bassik MC, Walensky LD, et al. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2002;2:183-92
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
-
23
-
-
0142246441
-
Loss of Omi mitochondrial protease activity causes the neuromuscular disorder mnd2 mutant mice
-
Jones JM, Datta P, Srinivasula SM, et al. Loss of Omi mitochondrial protease activity causes the neuromuscular disorder mnd2 mutant mice. Nature 2003;425:721-27
-
(2003)
Nature
, vol.425
, pp. 721-727
-
-
Jones, J.M.1
Datta, P.2
Srinivasula, S.M.3
-
24
-
-
25444498785
-
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease
-
Strauss KM, Martins LM, Plun-Favreau H, et al. Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum Mol Genet 2005;15:2099-111
-
(2005)
Hum Mol Genet
, vol.15
, pp. 2099-2111
-
-
Strauss, K.M.1
Martins, L.M.2
Plun-Favreau, H.3
-
25
-
-
0037179691
-
The harlequin mouse mutation downregulates apoptosis-inducing factor
-
Klein JA, Longo-Guess CM, Rossmann MP, et al. The harlequin mouse mutation downregulates apoptosis-inducing factor. Nature 2002;419:367-74
-
(2002)
Nature
, vol.419
, pp. 367-374
-
-
Klein, J.A.1
Longo-Guess, C.M.2
Rossmann, M.P.3
-
26
-
-
0036263870
-
The crystal structure of the mouse apoptosis-inducing factor AIF
-
Mate MJ, Ortiz-Lombardia M, Boitel B, et al. The crystal structure of the mouse apoptosis-inducing factor AIF. Nat Struct Biol 2002;9:442-46
-
(2002)
Nat Struct Biol
, vol.9
, pp. 442-446
-
-
Mate, M.J.1
Ortiz-Lombardia, M.2
Boitel, B.3
-
27
-
-
0033565557
-
The mitochondrial permeability transition pore and its role in cell death
-
Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem J 1999;341:233-49
-
(1999)
Biochem J
, vol.341
, pp. 233-249
-
-
Crompton, M.1
-
30
-
-
4544280654
-
Mitochondria and aging: A role for the permeability transition?
-
Crompton M. Mitochondria and aging: A role for the permeability transition? Aging Cell 2004;3:3-6
-
(2004)
Aging Cell
, vol.3
, pp. 3-6
-
-
Crompton, M.1
-
31
-
-
0034079520
-
The p53/p63/p73 family of transcription factors: Overlapping and distinct functions
-
Levrero M, De Laurenzi V, Costanzo A, et al. The p53/p63/p73 family of transcription factors: Overlapping and distinct functions. J Cell Sci 2000;113:1661-70
-
(2000)
J Cell Sci
, vol.113
, pp. 1661-1670
-
-
Levrero, M.1
De Laurenzi, V.2
Costanzo, A.3
-
32
-
-
0242410719
-
p53- and drug-induced apoptotic responses mediated by BH3-only proteins Puma and Noxa
-
Villunger A, Michalak EM, Coultas L, et al. p53- and drug-induced apoptotic responses mediated by BH3-only proteins Puma and Noxa. Science 2003;302:1036-38
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
-
33
-
-
18144421236
-
Stress-induced p53 runs a transcription-independent death program
-
Erster S, Moll UM. Stress-induced p53 runs a transcription-independent death program. Biochem Biophys Res Commun 2005;331:843-50
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 843-850
-
-
Erster, S.1
Moll, U.M.2
-
34
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk JE, Kuwana T, Bouchier-Hayes L, et al. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 2004;303:1010-14
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
-
35
-
-
2342553892
-
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex
-
Leu JI-J, Dumont P, Hafey M, et al. Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. Nat Cell Biol 2004;6:443-50
-
(2004)
Nat Cell Biol
, vol.6
, pp. 443-450
-
-
Leu, J.I.-J.1
Dumont, P.2
Hafey, M.3
-
36
-
-
0027021442
-
Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain
-
Soong NW, Hinton DR, Cortopassi G, Arnheim N. Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain. Nat Genet 1992;2:318-23
-
(1992)
Nat Genet
, vol.2
, pp. 318-323
-
-
Soong, N.W.1
Hinton, D.R.2
Cortopassi, G.3
Arnheim, N.4
-
37
-
-
0027017232
-
Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age
-
Corral-Debrinski M, Horton T, Lott MT, et al. Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age. Nat Genet 1992;2:324-29
-
(1992)
Nat Genet
, vol.2
, pp. 324-329
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
-
38
-
-
0032936755
-
Etiology and pathogenesis of Parkinson's disease
-
Olanow CW, Tatton WG. Etiology and pathogenesis of Parkinson's disease. Ann Rev Neurosci 1999;22:123-44
-
(1999)
Ann Rev Neurosci
, vol.22
, pp. 123-144
-
-
Olanow, C.W.1
Tatton, W.G.2
-
39
-
-
0037675042
-
Incidence of Parkinson's disease: Variations by age, gender and race ethnicity
-
Van Den Eeden SK, Tanner CM, Bernstein AL, et al. Incidence of Parkinson's disease: Variations by age, gender and race ethnicity. Am J Epidemol 2003;157:1015-22
-
(2003)
Am J Epidemol
, vol.157
, pp. 1015-1022
-
-
Van Den Eeden, S.K.1
Tanner, C.M.2
Bernstein, A.L.3
-
40
-
-
0000244524
-
Disorders of movement and system degeneration
-
Graham DI, Lantos PL, eds. London: Arnold
-
Lowe J, Lennox G, Leigh PN. Disorders of movement and system degeneration. In: Graham DI, Lantos PL, eds. Greenfield's Neuropathology. London: Arnold, 1997:281-366
-
(1997)
Greenfield's Neuropathology
, pp. 281-366
-
-
Lowe, J.1
Lennox, G.2
Leigh, P.N.3
-
41
-
-
0035409575
-
Alpha-synuclein and neurodegenerative diseases
-
Goedert M. Alpha-synuclein and neurodegenerative diseases. Nat Rev Neurosci 2001;2:492-501
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 492-501
-
-
Goedert, M.1
-
42
-
-
33744982893
-
Etiology of Parkinson's disease
-
Schapira AHV. Etiology of Parkinson's disease. Neurology 2006;66 (suppl 4):S10-S23
-
(2006)
Neurology
, vol.66
, Issue.SUPPL. 4
-
-
Schapira, A.H.V.1
-
43
-
-
34447506680
-
Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration
-
In press
-
Martin LJ. Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration. Rev Neurosci. In press
-
Rev Neurosci
-
-
Martin, L.J.1
-
44
-
-
0023722437
-
Synuclein: A neuron-specific protein localized to the nucleus and presynaptic nerve terminals
-
Maroteaux L, Campanelli JT, Scheller RH. Synuclein: A neuron-specific protein localized to the nucleus and presynaptic nerve terminals. J Neurosci 1988;8:2804-15
-
(1988)
J Neurosci
, vol.8
, pp. 2804-2815
-
-
Maroteaux, L.1
Campanelli, J.T.2
Scheller, R.H.3
-
45
-
-
0034193399
-
Synucleins are developmentally expressed, and α-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
-
Murphy DD, Rueter SM, Trojanowski JQ, Lee VMY. Synucleins are developmentally expressed, and α-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons. J Neurosci 2000;20:3214-20
-
(2000)
J Neurosci
, vol.20
, pp. 3214-3220
-
-
Murphy, D.D.1
Rueter, S.M.2
Trojanowski, J.Q.3
Lee, V.M.Y.4
-
46
-
-
0033890821
-
Alpha-synuclein promotes mitochondrial deficit and oxidative stress
-
Hsu LJ, Sagara Y, Arroyo A, et al. Alpha-synuclein promotes mitochondrial deficit and oxidative stress. Am J Pathol 2000;157:401-10
-
(2000)
Am J Pathol
, vol.157
, pp. 401-410
-
-
Hsu, L.J.1
Sagara, Y.2
Arroyo, A.3
-
47
-
-
27944444154
-
Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism
-
Silvestri L, Caputo V, Bellacchio E, et al. Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism. Hum Mol Genet 2005;14:3477-92
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3477-3492
-
-
Silvestri, L.1
Caputo, V.2
Bellacchio, E.3
-
48
-
-
2942684871
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
Canet-Aviles RM, Wilson MA, Miller DW, et al. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc Natl Acad Sci U S A 2004;101:9103-108
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
-
49
-
-
4544273256
-
Parkinsonism, premature menopause, and mitochondrial DNA polymerase γ mutations: Clinical and molecular genetic study
-
Luoma P, Melberg A, Rinne JO, et al. Parkinsonism, premature menopause, and mitochondrial DNA polymerase γ mutations: Clinical and molecular genetic study. Lancet 2004;364:875-82
-
(2004)
Lancet
, vol.364
, pp. 875-882
-
-
Luoma, P.1
Melberg, A.2
Rinne, J.O.3
-
50
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson's disease
-
Bender A, Krishnan KJ, Morris CM, et al. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson's disease. Nat Genet 2006;38:515-17
-
(2006)
Nat Genet
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
-
51
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
Kraytsberg Y, Kudryavtseva E, McKee AC, et al. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat Genet 2006;38:518-20
-
(2006)
Nat Genet
, vol.38
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
-
52
-
-
0020680904
-
Chronic parkinsonism in human due to a product of meperidine-analog synthesis
-
Langston JW, Ballard P, Tetrud JW, Irwin I. Chronic parkinsonism in human due to a product of meperidine-analog synthesis. Science 1983;219:979-80
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
53
-
-
0021810979
-
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1, 2,5,6-tetrahydropyridine
-
Nicklas WJ, Vyas I, Heikkila RE. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Life Sci 1985;36:2503-508
-
(1985)
Life Sci
, vol.36
, pp. 2503-2508
-
-
Nicklas, W.J.1
Vyas, I.2
Heikkila, R.E.3
-
55
-
-
28044469874
-
K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons
-
Liss B, Haeckel O, Wildmann J, et al. K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons. Nat Neurosci 2005;8:1742-51
-
(2005)
Nat Neurosci
, vol.8
, pp. 1742-1751
-
-
Liss, B.1
Haeckel, O.2
Wildmann, J.3
-
56
-
-
5044224807
-
Genetic mouse models of Huntington's and Parkinson's diseases: Illuminating but imperfect
-
Levine MS, Cepeda C, Hickey MA, Fleming SM, Chesselet MF. Genetic mouse models of Huntington's and Parkinson's diseases: Illuminating but imperfect. Trends Neurosci 2004;27:691-97
-
(2004)
Trends Neurosci
, vol.27
, pp. 691-697
-
-
Levine, M.S.1
Cepeda, C.2
Hickey, M.A.3
Fleming, S.M.4
Chesselet, M.F.5
-
57
-
-
30644471051
-
Parkinson's disease α-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
Martin LJ, Pan Y, Price AC, et al. Parkinson's disease α-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J Neurosci 2006;26:41-50
-
(2006)
J Neurosci
, vol.26
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
-
59
-
-
0034864628
-
Apoptosis in amyotrophic lateral sclerosis: A review of the evidence
-
Sathasivam S, Ince PG, Shaw PJ. Apoptosis in amyotrophic lateral sclerosis: A review of the evidence. Neuropathol Appl Neurobiol 2001;27:257-74
-
(2001)
Neuropathol Appl Neurobiol
, vol.27
, pp. 257-274
-
-
Sathasivam, S.1
Ince, P.G.2
Shaw, P.J.3
-
60
-
-
0036176613
-
Mitochondrial involvement in amyotrophic lateral sclerosis
-
Menzies FM, Ince PG, Shaw PJ. Mitochondrial involvement in amyotrophic lateral sclerosis. Neurochem Int 2002;40:543-51
-
(2002)
Neurochem Int
, vol.40
, pp. 543-551
-
-
Menzies, F.M.1
Ince, P.G.2
Shaw, P.J.3
-
61
-
-
0030026832
-
Ultrastructural evidence for altered calcium in motor nerve terminals in amyotrophic lateral sclerosis
-
Siklos L, Engelhardt J, Harati Y, et al. Ultrastructural evidence for altered calcium in motor nerve terminals in amyotrophic lateral sclerosis. Ann Neurol 1996;39:203-16
-
(1996)
Ann Neurol
, vol.39
, pp. 203-216
-
-
Siklos, L.1
Engelhardt, J.2
Harati, Y.3
-
62
-
-
0036570159
-
Oxidatively modified protein in aging and disease
-
Beal MF. Oxidatively modified protein in aging and disease. Free Radic Biol Med 2002;32:797-803
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 797-803
-
-
Beal, M.F.1
-
63
-
-
0031865772
-
Metabolic dysfunction in familial, but not sporadic, amyotrophic lateral sclerosis
-
Browne SE, Bowling AC, Baik MJ, et al. Metabolic dysfunction in familial, but not sporadic, amyotrophic lateral sclerosis. J Neurochem 1998;71:281-87
-
(1998)
J Neurochem
, vol.71
, pp. 281-287
-
-
Browne, S.E.1
Bowling, A.C.2
Baik, M.J.3
-
64
-
-
0032745071
-
Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death
-
Borthwick GM, Johnson MA, Ince PG, Shaw PJ, Turnbull DM. Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death. Ann Neurol 1999;46:787-90
-
(1999)
Ann Neurol
, vol.46
, pp. 787-790
-
-
Borthwick, G.M.1
Johnson, M.A.2
Ince, P.G.3
Shaw, P.J.4
Turnbull, D.M.5
-
65
-
-
0033917463
-
Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis
-
Vielhaber S, Kunz D, Winkler K, et al. Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis. Brain 2000;123:1339-48
-
(2000)
Brain
, vol.123
, pp. 1339-1348
-
-
Vielhaber, S.1
Kunz, D.2
Winkler, K.3
-
66
-
-
0031915174
-
Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease
-
Comi GP, Bordoni A, Salani S, et al. Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease. Ann Neurol 1998;43:110-16
-
(1998)
Ann Neurol
, vol.43
, pp. 110-116
-
-
Comi, G.P.1
Bordoni, A.2
Salani, S.3
-
67
-
-
33644832850
-
Motor neuron disease in a patient with a mitochondrial tRNAIle mutation
-
Borthwick GM, Taylor RW, Walls TJ, et al. Motor neuron disease in a patient with a mitochondrial tRNAIle mutation. Ann Neurol 2006;59:570-74
-
(2006)
Ann Neurol
, vol.59
, pp. 570-574
-
-
Borthwick, G.M.1
Taylor, R.W.2
Walls, T.J.3
-
68
-
-
2342520177
-
Single-cell analysis of mtDNA levels in sporadic amyotrophic lateral sclerosis
-
Mawrin C, Kirches E, Krause G, et al. Single-cell analysis of mtDNA levels in sporadic amyotrophic lateral sclerosis. Neuroreport 2004;15:939-43
-
(2004)
Neuroreport
, vol.15
, pp. 939-943
-
-
Mawrin, C.1
Kirches, E.2
Krause, G.3
-
69
-
-
0032896327
-
Neuronal death in amyotrophic lateral sclerosis is apoptosis: Possible contribution of a programmed cell death mechanism
-
Martin LJ. Neuronal death in amyotrophic lateral sclerosis is apoptosis: Possible contribution of a programmed cell death mechanism. J Neuropathol Exp Neurol 1999;58:459-71
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 459-471
-
-
Martin, L.J.1
-
70
-
-
23744460521
-
Opportunities for neuroprotection in ALS using cell death mechanism rationales
-
Martin LJ, Liu Z. Opportunities for neuroprotection in ALS using cell death mechanism rationales. Drug Discov Today 2004;1:135-43
-
(2004)
Drug Discov Today
, vol.1
, pp. 135-143
-
-
Martin, L.J.1
Liu, Z.2
-
71
-
-
77955397778
-
Cell and tissue microdissection in combination with genomic and proteomic profiling
-
Zaborszky L, Wouterlood FG, Lanciego JL, eds. New York: Springer
-
Ginsberg SD, Hemby SE, Mufson EJ, Martin LJ. Cell and tissue microdissection in combination with genomic and proteomic profiling. In: Zaborszky L, Wouterlood FG, Lanciego JL, eds. Neuroanatomical Tract-Tracing 3. Molecules, Neurons, and Systems. New York: Springer, 2006:109-41
-
(2006)
Neuroanatomical Tract-Tracing 3. Molecules, Neurons, and Systems
, pp. 109-141
-
-
Ginsberg, S.D.1
Hemby, S.E.2
Mufson, E.J.3
Martin, L.J.4
-
72
-
-
0034517935
-
p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis
-
Martin LJ. p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis. Neurobiol Dis 2000;7:613-22
-
(2000)
Neurobiol Dis
, vol.7
, pp. 613-622
-
-
Martin, L.J.1
-
73
-
-
0037083204
-
Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent
-
Martin LJ, Liu Z. Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent. J Neurobiol 2002;50:181-97
-
(2002)
J Neurobiol
, vol.50
, pp. 181-197
-
-
Martin, L.J.1
Liu, Z.2
-
74
-
-
33845361630
-
Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: Mechanisms of mitochondropathy and cell death
-
2007
-
Martin LJ, Liu Z, Chen K, et al. Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: Mechanisms of mitochondropathy and cell death. J Comp Neurol 2007;500:20-46
-
J Comp Neurol
, vol.500
, pp. 20-46
-
-
Martin, L.J.1
Liu, Z.2
Chen, K.3
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