Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent

Journal of Neurobiology

Volumn 50, Issue 3, 2002, Pages 181-197

  Martin, Lee J ^a   Liu, Zhiping ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amyotrophic lateral sclerosis; Bax mice; DNA damage; P53 mice; Spinal cord trauma

Indexed keywords

CASPASE 3; CYTOCHROME C; PROTEIN BAX; PROTEIN P53; SINGLE STRANDED DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME ACTIVATION; IMMUNOCYTOCHEMISTRY; IMMUNOGOLD ELECTRON MICROSCOPY; MALE; MITOCHONDRION; NERVE DEGENERATION; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL CORD; SPINAL CORD MOTONEURON;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASES; CELL COUNT; CYTOCHROME C GROUP; DNA; DNA DAMAGE; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MOTOR NEURONS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SPINAL CORD INJURIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0037083204     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.10026     Document Type: Article

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