Potent adenosine A1 and A2A receptors antagonists: Recent developments

Current Medicinal Chemistry

Volumn 13, Issue 30, 2006, Pages 3609-3625

  Yuzlenko, O ^a   Kiec Kononowicz K ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

A1 adenosine receptor antagonists; A2A adenosine receptor antagonists; Nitrogen (poly)heterocyclic compounds; Xanthine derivatives

Indexed keywords

1 PHENYLPYRAZOLO[3,4 D]PYRIMIDINE DERIVATIVE; 1,3 DIPROPYL 8 [1 (4 PROPIONATE)BICYCLO[2,2,2]OCTYL]XANTHINE; 1,3 DIPROPYL 8 [2 (5,6 EPOXYNORBORNYL)]XANTHINE; 2 AMINO 4 (3 TRIFLUOROMETHYLPHENYL) 6 (2 HYDROXYETHYLSULFANYL)PYRIDINE 3,5 DICARBONITRILE; 2 AMINO 4 (4 DIFLUOROMETHOXYPHENYL) 6 (2 HYDROXYETHYLSULFANYL)PYRIDINE 3,5 DICARBONITRILE; 2 AMINO 4 BENZO[1,3]DIOXO 5 YL 6 (2 HYDROXYETHYLSULFANYL)PYRIDINE 3,5 DICARBONITRILE; 3 (2 CYCLOHEXENYL 3 OXO 2,3 DIHYDROPYRIDAZIN 6 YL) 2 PHENYLPYRAZOLO[1,5 A]PYRIDINE DERIVATIVE; 3 [4 (2,3,6,7 TETRAHYDRO 2,6 DIOXO 1,3 DIPROPYL 1H PURIN 8 YL)BICYCLO[2.2.2]OCTAN 1 YL]PROPIONIC ACID; 3 [4 (8 ALKYL 5 OXO 4 PROPYL 4,5,7,8 TETRAHYDRO 1H IMIDAZO[1,2 G]PURIN 2 YL)BICYCLO[2.2.2]OCTAN 1 YL]PROPANOIC ACID DERIVATIVE; 3 METHYL 1 PROPYL 8 [4 (6 CHLOROPYRIDAZIN 3(2H) ONE 2 YL)BUTYL]XANTHINE; 4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 6 OXO 3 (2 PHENYLPYRAZOLO[1,5 A]PYRIDIN 3 YL) 1(6H) PYRIDAZINEBUTYRIC ACID; 8 (2 NOR 1 ADAMANTYL) 1,3 DIPROPYLXANTHINE; 8 CYCLOALKYLXANTHINE DERIVATIVE; 8 CYCLOPENTYL 1 PROPYLXANTHINE DERIVATIVE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; 9 ETHYL 8 PHENYL 9H ADENINE; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; ADENOSINE RECEPTOR BLOCKING AGENT; CAFFEINE; FR 166124; HETEROCYCLIC COMPOUND; ISTRADEFYLLINE; LUF 5437; LUF 5826; LUF 5853; N (3 PHENYL 1,2,4 THIADIAZOL 5 YL) 4 HYDROXYBENZAMIDE; N (3 PHENYL 1,2,4 THIADIAZOL 5 YL) 4 HYDROXYCYCLOHEXANAMIDE; N (4 PHENYLTHIAZOL 2 YL) 4 CHLOROBENZAMIDE DERIVATIVE; N 0840; N 6 CYCLOPENTYL 9 METHYLADENINE; N METHYLISOPROPYLAMINO DERIVATIVE; NAXIFYLLINE; THEOPHYLLINE; UNINDEXED DRUG; VUF 5472; ADENOSINE RECEPTOR;

ACUTE KIDNEY FAILURE; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANTINEOPLASTIC ACTIVITY; BINDING AFFINITY; BRAIN ISCHEMIA; CLINICAL TRIAL; DRUG BIOAVAILABILITY; DRUG DOSE REGIMEN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; EPILEPSY; HUMAN; HYPERTENSION; NONHUMAN; PARKINSON DISEASE; PHOTOSENSITIVITY; RECEPTOR BINDING; RESTLESSNESS; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; CLASSIFICATION; DRUG ANTAGONISM; DRUG DESIGN;

ANIMALS; DRUG DESIGN; HUMANS; RECEPTORS, PURINERGIC P1;

EID: 33845347343     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986706779026093     Document Type: Review

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