Tricyclic oxazolo[2,3-f]purinediones: Potency as adenosine receptor ligands and anticonvulsants

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 18, 2004, Pages 4895-4908

  Drabczyńska, Anna ^a   Müller, Christa E ^b   Schumacher, Britta ^b   Hinz, Sonja ^b   Karolak Wojciechowska, Janina ^c   Michalak, Barbara ^a   Pȩkala, Elzbieta ^a   Kieć Kononowicz, Katarzyna ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b UNIVERSITY OF BONN   (Germany)

^c LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

1,3 Oxazolo 2,3 f purinediones; A 2A receptor antagonists; Adenosine A 1; Anticonvulsant activity; Tricyclic xanthine derivatives

Indexed keywords

ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR; ADENOSINE RECEPTOR; ANTICONVULSIVE AGENT; OXAZOLE DERIVATIVE; PURINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG ACTIVITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; EVALUATION; LIGAND BINDING; LIPOPHILICITY; NEUROTOXICITY; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANIMALS; ANTICONVULSANTS; HUMANS; LIGANDS; MALE; MICE; OXAZOLES; PROTEIN BINDING; PURINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P1;

EID: 4444320781     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.06.043     Document Type: Article

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