erythro- and threo-2-Hydroxynonyl substituted 2-phenyladenines and 2-phenyl-8-azaadenines: Ligands for A1 adenosine receptors and adenosine deaminase

Farmaco

Volumn 57, Issue 3, 2002, Pages 221-233

  Biagi, Giuliana ^a   Giorgi, Irene ^a   Livi, Oreste ^a   Pacchini, Federica ^a   Rum, Pietro ^a   Scartoni, Valerio ^a   Costa, Barbara ^a   Mazzoni, Maria Rosa ^a   Giusti, Laura ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

A1 adenosine receptor ligands; Adenosine deaminase inhibitors; Hydroxynonyl 8 azaadenines; Hydroxynonyl adenines

Indexed keywords

ADENINE DERIVATIVE; ADENOSINE A1 RECEPTOR; ADENOSINE DEAMINASE; ADENOSINE DEAMINASE INHIBITOR; ERYTHRO 2 PHENYL 9 (2 HYDROXY 3 NONYL)ADENINE; HETEROCYCLIC COMPOUND; LIGAND; UNCLASSIFIED DRUG; 8 AZAADENINE; 8-AZAADENINE; 9 (2 HYDROXY 3 NONYL)ADENINE; 9-(2-HYDROXY-3-NONYL)ADENINE; ADENINE; ADENOSINE RECEPTOR; DRUG DERIVATIVE; ENZYME INHIBITOR;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; ENZYME ACTIVITY; HUMAN; NONHUMAN; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; STEREOCHEMISTRY; ANIMAL; BINDING COMPETITION; BRAIN CORTEX; CATTLE; CHEMISTRY; DRUG ANTAGONISM; IC 50; MASS SPECTROMETRY; METABOLISM; NEOSTRIATUM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIOASSAY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ADENINE; ADENOSINE DEAMINASE; ANIMALS; AZA COMPOUNDS; BINDING, COMPETITIVE; CATTLE; CEREBRAL CORTEX; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; NEOSTRIATUM; RADIOLIGAND ASSAY; RECEPTORS, PURINERGIC P1; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036513937     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(02)01200-4     Document Type: Article

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