9-Ethyladenine derivatives as adenosine receptor antagonists: 2- and 8-substitution results in distinct selectivities

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 367, Issue 6, 2003, Pages 629-634

  Klotz, Karl Norbert ^a   Kachler, Sonja ^a   Lambertucci, Catia ^b   Vittori, Sauro ^b   Volpini, Rosaria ^b   Cristalli, Gloria ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF CAMERINO   (Italy)

Author keywords

Adenine; Adenosine; Adenosine receptor; Antagonist

Indexed keywords

6 (1 BUTYLAMINO) 9 ETHYL 8 PHENYL 9H PURINE; 8 ETHOXY 9 ETHYL 8 PHENYLETHYNYL 9H ADENINE; 9 ETHYL 8 PHENYL 9H ADENINE; ADENINE DERIVATIVE; ADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG SELECTIVITY; ENZYME ACTIVITY;

ADENINE; ANIMALS; CHO CELLS; CRICETINAE; HUMANS; RECEPTORS, PURINERGIC P1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037966065     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-003-0749-9     Document Type: Article

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