A1 adenosine receptor antagonists, 3-aryl[1,2,4]triazino[4,3-a] benzimidazol-4-(10H)-ones (ATBIs) and N-alkyl and N-acyl-(7-substituted-2- phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs): Different recognition of bovine and human binding sites

Drug Development Research

Volumn 63, Issue 1, 2004, Pages 1-7

  Da Settimo, Federico ^a   Primofiore, Giampaolo ^a   Taliani, Sabrina ^a   La Motta, Concettina ^a   Novellino, Ettore ^b   Greco, Giovanni ^b   Lavecchia, Antonio ^b   Cosimelli, Barbara ^b   Iadanza, Manuela ^b   Klotz, Karl Norbert ^c   Tuscano, Daniela ^a   Trincavelli, Maria Letizia ^a   Martini, Claudia ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

3 aryl 1,2,4 triazino 4,3 a benzimidazol 4 (10H) ones (ATBIs); Adenosine antagonists; Bovine and human A1 adenosine receptors; N alkyl and N acyl (7 substituted 2 phenylimidazo 1,2 a 1,3,5 triazin 4 yl)amines (ITAs); Structure activity relationships

Indexed keywords

3 ARYL 1,2,4 TRIAZINO 4,3 ALPHA BENZIMIDAZOL 4 10H ONE; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE A3 RECEPTOR ANTAGONIST; AMINO ACID; N ACYL 7 SUBSTITUTED 2 PHENYLIMIDAZ 1,2 ALPHA 1,3,3 TRIAZIN 4 YL AMINE; N ALKYL 7 SUBSTITUTED 2 PHENYLIMIDAZO 1,2 ALPHA 1,3,3 TRIAZIN 4 YL AMINE; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN CORTEX; CHEMICAL STRUCTURE; CHO CELL; COW; DISSOCIATION CONSTANT; DRUG STRUCTURE; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR INTERACTION; NONHUMAN; RECEPTOR AFFINITY; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

EID: 19944428678     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10366     Document Type: Article

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