Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA

Nature

Volumn 437, Issue 7057, 2005, Pages 440-443

  Moreno Herrero, Fernando ^a   De Jager, Martijn ^b   Dekker, Nynke H ^a   Kanaar, Roland ^b   Wyman, Claire ^b   Dekker, Cees ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CONFORMATIONS; NANOTECHNOLOGY;

BIOLOGICAL FUNCTIONS; DNA TETHERING; DNA-REPAIR COMPLEX; MESOSCALE CONFORMATIONAL CHANGES;

DNA;

DNA; DNA BINDING PROTEIN; GLOBULAR PROTEIN; MRE11 PROTEIN; NIBRIN; RAD50 PROTEIN; UNCLASSIFIED DRUG; ADENYLYLIMIDODIPHOSPHATE; BUFFER; CELL CYCLE PROTEIN; LIGAND; MRE11A PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; NBS1 PROTEIN, HUMAN; NUCLEAR PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RAD50 PROTEIN, HUMAN;

BIOLOGY;

ARTICLE; CONFORMATIONAL TRANSITION; DNA BINDING; DNA REPAIR; DNA STRUCTURE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; ATOMIC FORCE MICROSCOPY; CHEMISTRY; CONFORMATION; HUMAN; METABOLISM; PLIABILITY; PROTEIN BINDING; ULTRASTRUCTURE;

ADENYLYL IMIDODIPHOSPHATE; BUFFERS; CELL CYCLE PROTEINS; DNA; DNA REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; HUMANS; LIGANDS; MICROSCOPY, ATOMIC FORCE; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; NUCLEIC ACID CONFORMATION; PLIABILITY; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 24944540931     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature03927     Document Type: Article

References (11)

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