Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability

Oncogene

Volumn 23, Issue 15, 2004, Pages 2640-2647

  Giannini, Giuseppe ^a   Rinaldi, Christian ^b   Ristori, Elisabetta ^a   Ambrosini, Maria Irene ^c   Cerignoli, Fabio ^a   Viel, Alessandra ^d   Bidoli, Ettore ^d   Berni, Silvia ^a   D'Amati, Giulia ^a   Scambia, Giovanni ^e   Frati, Luigi ^a,b   Screpanti, Isabella ^a,f   Gulino, Alberto ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^e CATHOLIC UNIVERSITY   (Italy)

^f Pasteur Institute   (Italy)

Author keywords

Colorectal cancer; DNA double strand breaks repair; MMR defect; MRE11; NBS1

Indexed keywords

MRE11 PROTEIN; NIBRIN; PROTEIN; RAD50 PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ARTICLE; CANCER STAGING; CARCINOGENESIS; CLINICAL ARTICLE; COLORECTAL CANCER; COMPLEX FORMATION; CONTROLLED STUDY; DISEASE ASSOCIATION; ENDOMETRIUM CANCER; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC DISORDER; HUMAN; HUMAN CELL; INTRON; MALE; MICROSATELLITE INSTABILITY; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; RNA SPLICING;

AGED; ALLELES; BASE PAIR MISMATCH; CELL CYCLE PROTEINS; CELL LINE; COLORECTAL NEOPLASMS; DNA REPAIR; DNA SEQUENCE, UNSTABLE; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; EXODEOXYRIBONUCLEASES; EXONS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTRONS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; NEOPLASMS; NUCLEAR PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; TUMOR CELLS, CULTURED;

EID: 2342467382     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207409     Document Type: Article

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