-
1
-
-
0031466618
-
Ataxia-telangiectasia and the Nijmegen breakage syndrome - Related disorders but genes apart
-
Shiloh, Y. Ataxia-telangiectasia and the Nijmegen Breakage Syndrome - related disorders but genes apart. Annu. Rev. Genet. 31, 635-662 (1997).
-
(1997)
Annu. Rev. Genet.
, vol.31
, pp. 635-662
-
-
Shiloh, Y.1
-
2
-
-
0029057336
-
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky, K. et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268, 1749-1753 (1995).
-
(1995)
Science
, vol.268
, pp. 1749-1753
-
-
Savitsky, K.1
-
3
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
Banin, S. et al. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281, 1674-1677 (1998).
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
-
4
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
Canman, C. E. et al. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281, 1677-1679 (1998).
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
-
5
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
-
Matsuoka, S., Huang, M. & Elledge, S. J. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 282, 1893-1897 (1998).
-
(1998)
Science
, vol.282
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
6
-
-
0033616828
-
A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage
-
Brown, A. L. et al. A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage. Proc. Natl Acad. Sci. USA 94, 3745-3750 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 3745-3750
-
-
Brown, A.L.1
-
7
-
-
0033527717
-
Requirement of ATM-dependent phosphorylation of Brca l in the DNA damage response to double-strand breaks
-
Cortez, D., Wang, Y., Qin, J. & Elledge, S. J. Requirement of ATM-dependent phosphorylation of Brca l in the DNA damage response to double-strand breaks. Science 286, 1162-1166 (1999).
-
(1999)
Science
, vol.286
, pp. 1162-1166
-
-
Cortez, D.1
Wang, Y.2
Qin, J.3
Elledge, S.J.4
-
8
-
-
0030977349
-
Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family
-
Hoekstra, M. F. Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family. Curr. Opin. Genet. Dev. 7, 170-175 (1997).
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 170-175
-
-
Hoekstra, M.F.1
-
9
-
-
0032189483
-
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
-
Sarkaria, J. et al. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. Cancer Res. 58, 4375-4382 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 4375-4382
-
-
Sarkaria, J.1
-
10
-
-
0030797708
-
Recombinant ATM protein complements the cellular A-T phenotype
-
Ziv, Y. et al. Recombinant ATM protein complements the cellular A-T phenotype. Oncogene 15, 159-167 (1997).
-
(1997)
Oncogene
, vol.15
, pp. 159-167
-
-
Ziv, Y.1
-
11
-
-
0033621392
-
Substrate specificities and identification of putative substrates of ATM kinase family members
-
Kim, S. -T., Lim, D. -S., Canman, C. E. & Kastan, M. B. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274, 37538-37543 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37538-37543
-
-
Kim, S.-T.1
Lim, D.-S.2
Canman, C.E.3
Kastan, M.B.4
-
12
-
-
0034725592
-
Utilization of oriented peptide libraries to identify substrate motifs selected by ATM and DNA-PK
-
in the press
-
O'Neill, T. et al. Utilization of oriented peptide libraries to identify substrate motifs selected by ATM and DNA-PK. J. Biol. Chem. (in the press).
-
J. Biol. Chem.
-
-
O'Neill, T.1
-
13
-
-
0343983147
-
Independence of Nbsl/Mrel 1/Rad50 nuclear focus formation and the presence of intact BRCA
-
in the press
-
Wu, X., Petrini, J. H. J., Weaver, D. T., Livingston, D. M. & Chen, J. Independence of Nbsl/Mrel 1/Rad50 nuclear focus formation and the presence of intact BRCA. Science (in the press).
-
Science
-
-
Wu, X.1
Petrini, J.H.J.2
Weaver, D.T.3
Livingston, D.M.4
Chen, J.5
-
14
-
-
0343983146
-
Rescue of a telomere length defect of Nijmegen breakage syndrome cells by NBS and Telomerase catalytic subunity
-
submitted
-
Ciccone, D. N. et al. Rescue of a telomere length defect of Nijmegen breakage syndrome cells by NBS and Telomerase catalytic subunity. Nature Genet. (submitted).
-
Nature Genet.
-
-
Ciccone, D.N.1
-
15
-
-
0033544724
-
The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder
-
Stewart, G. et al. The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder. Cell 99, 577-587 (1999).
-
(1999)
Cell
, vol.99
, pp. 577-587
-
-
Stewart, G.1
-
16
-
-
0033594904
-
Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation
-
Luo, G. et al. Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation. Proc. Natl Acad. Sci. USA 96, 7376-7381 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 7376-7381
-
-
Luo, G.1
-
17
-
-
0033485758
-
Mrel1 is essential for the maintenance of chromosomal DNA in vertebrate cells
-
Yamaguchi-Iwai, Y. et al. Mrel1 is essential for the maintenance of chromosomal DNA in vertebrate cells. EMBO J. 18, 6619-6629 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 6619-6629
-
-
Yamaguchi-Iwai, Y.1
-
18
-
-
0032076248
-
The hMrel1/Rad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response
-
Carney, J. P. et al. The hMrel1/Rad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell 93, 477-486 (1998).
-
(1998)
Cell
, vol.93
, pp. 477-486
-
-
Carney, J.P.1
-
19
-
-
0033563229
-
Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mrel1/Rad50 complex
-
Paull, T. T. & Gellert, M. Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mrel1/Rad50 complex. Genes Dev. 13, 1276-1288 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 1276-1288
-
-
Paull, T.T.1
Gellert, M.2
-
20
-
-
0033618621
-
Association of BRCA1 with the hRad50-hMrel1-p95 complex and the DNA damage response
-
Zhong, Q. et al. Association of BRCA1 with the hRad50-hMrel1-p95 complex and the DNA damage response. Science 285, 747-750 (1999).
-
(1999)
Science
, vol.285
, pp. 747-750
-
-
Zhong, Q.1
-
21
-
-
0030850047
-
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
-
Scully, R. et al. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 90, 425-435 (1997).
-
(1997)
Cell
, vol.90
, pp. 425-435
-
-
Scully, R.1
-
22
-
-
0031472370
-
Association of BRCA1 with Rad51 in mitotic and meiotic cells
-
Scully, R. et al. Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell 88, 265-275 (1997).
-
(1997)
Cell
, vol.88
, pp. 265-275
-
-
Scully, R.1
-
23
-
-
0033617368
-
Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl
-
Chen, G. et al. Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl. J. Biol. Chem. 274, 12748-12752 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12748-12752
-
-
Chen, G.1
-
24
-
-
0033213392
-
Brca1 controls homology-directed DNA repair
-
Moynahan, M. E., Chiu, J. W., Koller, B. H. & Jasin, M. Brca1 controls homology-directed DNA repair. Mol. Cell 4, 511-518 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 511-518
-
-
Moynahan, M.E.1
Chiu, J.W.2
Koller, B.H.3
Jasin, M.4
-
25
-
-
0033400828
-
Genetic analysis of BRCA1 function in a defined tumor cell line
-
Scully, R. et al. Genetic analysis of BRCA1 function in a defined tumor cell line. Mol. Cell 4, 1093-1099 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 1093-1099
-
-
Scully, R.1
-
26
-
-
0025268280
-
An increased risk for malignant neoplasms in heterozygotes for a syndrome of microcephaly, normal intelligence, growth retardation, remarkable facies, immunodeficiency and chromosomal instability
-
Secmanova, E. An increased risk for malignant neoplasms in heterozygotes for a syndrome of microcephaly, normal intelligence, growth retardation, remarkable facies, immunodeficiency and chromosomal instability. Mutat. Res. 238, 321-324 (1990).
-
(1990)
Mutat. Res.
, vol.238
, pp. 321-324
-
-
Secmanova, E.1
-
27
-
-
0030482567
-
Molecular genotyping shows that ataxia-telangiectasia heterozygotes are predisposed to breast cancer
-
Athma, P., Rappaport, R. & Swift, M. Molecular genotyping shows that ataxia-telangiectasia heterozygotes are predisposed to breast cancer. Cancer Genet. Cytogenet. 92, 130-134 (1996).
-
(1996)
Cancer Genet. Cytogenet.
, vol.92
, pp. 130-134
-
-
Athma, P.1
Rappaport, R.2
Swift, M.3
-
28
-
-
0032483043
-
Rabbit b-globin is extended beyond its UGA slop codon by multiple suppressions and translational reading gaps
-
Chittum, H. S. et al. Rabbit b-globin is extended beyond its UGA slop codon by multiple suppressions and translational reading gaps. Biochemistry 37, 10866-10870 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 10866-10870
-
-
Chittum, H.S.1
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