Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

EMBO Journal

Volumn 18, Issue 5, 1999, Pages 1397-1406

  Shao, Rong Guang ^a   Cao, Chun Xia ^a   Zhang, Hongliang ^a   Kohn, Kurt W ^a   Wold, Marc S ^b   Pommier, Yves ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Camptothecin; DNA damage; DNA dependent protein kinase; RPA2 phosphorylation

Indexed keywords

7 HYDROXYSTAUROSPORINE; AUTOANTIGEN; CAMPTOTHECIN; DNA DEPENDENT PROTEIN KINASE; DNA TOPOISOMERASE INHIBITOR; ETOPOSIDE; MUTANT PROTEIN; PROTEIN P53; PROTEIN SUBUNIT; REPLICATION PROTEIN A;

ARTICLE; ATAXIA TELANGIECTASIA; CELL CYCLE; CELL CYCLE S PHASE; CYTOTOXICITY; DNA CLEAVAGE; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME KINETICS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

EID: 0033104517     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.5.1397     Document Type: Article

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