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Volumn 23, Issue 5, 2004, Pages 1178-1187

The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways

Author keywords

DNA repair; Fanconi anemia; S phase checkpoint

Indexed keywords

ATM PROTEIN; ATR PROTEIN; BRCA1 PROTEIN; CHECKPOINT KINASE 1; FANCONI ANEMIA GROUP D2 PROTEIN; GENE PRODUCT; MRE11 PROTEIN; NIBRIN; PHOSPHOTRANSFERASE; RAD50 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 1842576658     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600113     Document Type: Article
Times cited : (187)

References (54)
  • 1
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham RT (2001) Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 15: 2177-2196
    • (2001) Genes Dev , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 2
    • 0036013778 scopus 로고    scopus 로고
    • Molecular biology of Fanconi anaemia-an old problem, a new insight
    • Ahmad SI, Hanaoka F, Kirk SH (2002) Molecular biology of Fanconi anaemia-an old problem, a new insight. Bioessays 24: 439-448
    • (2002) Bioessays , vol.24 , pp. 439-448
    • Ahmad, S.I.1    Hanaoka, F.2    Kirk, S.H.3
  • 3
    • 0033780760 scopus 로고    scopus 로고
    • DNA replication is required to elicit cellular responses to psoralen-induced DNA interstrand cross-links
    • Akkari YM, Bateman RL, Reifsteck CA, Olson SB, Grompe M (2000) DNA replication is required to elicit cellular responses to psoralen-induced DNA interstrand cross-links. Mol Cell Biol 20: 8283-8289
    • (2000) Mol Cell Biol , vol.20 , pp. 8283-8289
    • Akkari, Y.M.1    Bateman, R.L.2    Reifsteck, C.A.3    Olson, S.B.4    Grompe, M.5
  • 4
    • 0035545996 scopus 로고    scopus 로고
    • Mammalian G1- and S-phase checkpoints in response to DNA damage
    • Bartek J, Lukas J (2001) Mammalian G1- and S-phase checkpoints in response to DNA damage. Curr Opin Cell Biol 13: 738-747
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 738-747
    • Bartek, J.1    Lukas, J.2
  • 5
    • 0031927305 scopus 로고    scopus 로고
    • Is Fanconi anemia caused by a defect in the processing of DNA damage?
    • Buchwald M, Moustacchi E (1998) Is Fanconi anemia caused by a defect in the processing of DNA damage? Mutat Res 408: 75-90
    • (1998) Mutat Res , vol.408 , pp. 75-90
    • Buchwald, M.1    Moustacchi, E.2
  • 6
    • 0034332550 scopus 로고    scopus 로고
    • Damage-resistant DNA synthesis in Fanconi anemia cells treated with a DNA cross-linking agent
    • Centurion SA, Kuo HR, Lambert WC (2000) Damage-resistant DNA synthesis in Fanconi anemia cells treated with a DNA cross-linking agent. Exp Cell Res 260: 216-221
    • (2000) Exp Cell Res , vol.260 , pp. 216-221
    • Centurion, S.A.1    Kuo, H.R.2    Lambert, W.C.3
  • 7
    • 0032472330 scopus 로고    scopus 로고
    • Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints
    • Cliby WA, Roberts CJ, Cimprich KA, Stringer CM, Lamb JR, Schreiber SL, Friend SH (1998) Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints. EMBO J 17: 159-169
    • (1998) EMBO J , vol.17 , pp. 159-169
    • Cliby, W.A.1    Roberts, C.J.2    Cimprich, K.A.3    Stringer, C.M.4    Lamb, J.R.5    Schreiber, S.L.6    Friend, S.H.7
  • 8
  • 9
    • 0030884238 scopus 로고    scopus 로고
    • Molecular biology of Fanconi anemia: Implications for diagnosis and therapy
    • D'Andrea AD, Grompe M (1997) Molecular biology of Fanconi anemia: implications for diagnosis and therapy. Blood 90: 1725-1736
    • (1997) Blood , vol.90 , pp. 1725-1736
    • D'Andrea, A.D.1    Grompe, M.2
  • 10
    • 0037268338 scopus 로고    scopus 로고
    • The Fanconi anaemia/BRCA pathway
    • D'Andrea AD, Grompe M (2003) The Fanconi anaemia/BRCA pathway. Nat Rev Cancer 3: 23-34
    • (2003) Nat Rev Cancer , vol.3 , pp. 23-34
    • D'Andrea, A.D.1    Grompe, M.2
  • 11
    • 0033781210 scopus 로고    scopus 로고
    • Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells
    • De Silva IU, McHugh PJ, Clingen PH, Hartley JA (2000) Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells. Mol Cell Biol 20: 7980-7990
    • (2000) Mol Cell Biol , vol.20 , pp. 7980-7990
    • De Silva, I.U.1    McHugh, P.J.2    Clingen, P.H.3    Hartley, J.A.4
  • 15
    • 0035807079 scopus 로고    scopus 로고
    • Repair of DNA interstrand crosslinks
    • Dronkert ML, Kanaar R (2001) Repair of DNA interstrand crosslinks. Mutat Res 486: 217-247
    • (2001) Mutat Res , vol.486 , pp. 217-247
    • Dronkert, M.L.1    Kanaar, R.2
  • 18
    • 0031835895 scopus 로고    scopus 로고
    • The fidelity of double strand breaks processing is impaired in complementation groups B and D of Fanconi anemia, a genetic instability syndrome
    • Escarceller M, Rousset S, Moustacchi E, Papadopoulo D (1997) The fidelity of double strand breaks processing is impaired in complementation groups B and D of Fanconi anemia, a genetic instability syndrome. Somat Cell Mol Genet 23: 401-411
    • (1997) Somat Cell Mol Genet , vol.23 , pp. 401-411
    • Escarceller, M.1    Rousset, S.2    Moustacchi, E.3    Papadopoulo, D.4
  • 19
    • 0036510055 scopus 로고    scopus 로고
    • The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways
    • Falck J, Petrini JH, Williams BR, Lukas J, Bartek J (2002) The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nat Genet 30: 290-294
    • (2002) Nat Genet , vol.30 , pp. 290-294
    • Falck, J.1    Petrini, J.H.2    Williams, B.R.3    Lukas, J.4    Bartek, J.5
  • 22
    • 0033969865 scopus 로고    scopus 로고
    • Loss of the Fanconi anemia group C protein activity results in an inability to activate caspase-3 after ionizing radiation
    • Guillouf C, Vit JP, Rosselli F (2000) Loss of the Fanconi anemia group C protein activity results in an inability to activate caspase-3 after ionizing radiation. Biochimie 82: 51-58
    • (2000) Biochimie , vol.82 , pp. 51-58
    • Guillouf, C.1    Vit, J.P.2    Rosselli, F.3
  • 23
    • 0033080442 scopus 로고    scopus 로고
    • Fanconi anemia C protein acts at a switch between apoptosis and necrosis in mitomycin C-induced cell death
    • Guillouf C, Wang TS, Liu J, Walsh CE, Poirier GG, Moustacchi E, Rosselli F (1999) Fanconi anemia C protein acts at a switch between apoptosis and necrosis in mitomycin C-induced cell death. Exp Cell Res 246: 384-394
    • (1999) Exp Cell Res , vol.246 , pp. 384-394
    • Guillouf, C.1    Wang, T.S.2    Liu, J.3    Walsh, C.E.4    Poirier, G.G.5    Moustacchi, E.6    Rosselli, F.7
  • 24
    • 0032101030 scopus 로고    scopus 로고
    • Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice
    • Haneline LS, Broxmeyer HE, Cooper S, Hangoc G, Carreau M, Buchwald M, Clapp DW (1998) Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice. Blood 91: 4092-4098
    • (1998) Blood , vol.91 , pp. 4092-4098
    • Haneline, L.S.1    Broxmeyer, H.E.2    Cooper, S.3    Hangoc, G.4    Carreau, M.5    Buchwald, M.6    Clapp, D.W.7
  • 26
    • 0034649590 scopus 로고    scopus 로고
    • Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint
    • Hekmat-Nejad M, You Z, Yee MC, Newport JW, Cimprich KA (2000) Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint. Curr Biol 10: 1565-1573
    • (2000) Curr Biol , vol.10 , pp. 1565-1573
    • Hekmat-Nejad, M.1    You, Z.2    Yee, M.C.3    Newport, J.W.4    Cimprich, K.A.5
  • 28
    • 0020062586 scopus 로고
    • Abnormal regulation of DNA replication and increased lethality in ataxia telangiectasia cells exposed to carcinogenic agents
    • Jaspers NG, de Wit J, Regulski MR, Bootsma D (1982) Abnormal regulation of DNA replication and increased lethality in ataxia telangiectasia cells exposed to carcinogenic agents. Cancer Res 42: 335-341
    • (1982) Cancer Res , vol.42 , pp. 335-341
    • Jaspers, N.G.1    De Wit, J.2    Regulski, M.R.3    Bootsma, D.4
  • 29
    • 0030933152 scopus 로고    scopus 로고
    • The genetic defect in ataxia-telangiectasia
    • Lavin MF, Shiloh Y (1997) The genetic defect in ataxia-telangiectasia. Annu Rev Immunol 15: 177-202
    • (1997) Annu Rev Immunol , vol.15 , pp. 177-202
    • Lavin, M.F.1    Shiloh, Y.2
  • 32
    • 0035436539 scopus 로고    scopus 로고
    • Repair of DNA interstrand crosslinks: Molecular mechanisms and clinical relevance
    • McHugh PJ, Spanswick VJ, Hartley JA (2001) Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance. Lancet Oncol 2: 483-490
    • (2001) Lancet Oncol , vol.2 , pp. 483-490
    • McHugh, P.J.1    Spanswick, V.J.2    Hartley, J.A.3
  • 35
    • 0034749425 scopus 로고    scopus 로고
    • DNA damage-dependent nuclear dynamics of the Mre11 complex
    • Mirzoeva OK, Petrini JH (2001) DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol Cell Biol 21: 281-288
    • (2001) Mol Cell Biol , vol.21 , pp. 281-288
    • Mirzoeva, O.K.1    Petrini, J.H.2
  • 37
    • 0345073699 scopus 로고    scopus 로고
    • A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
    • O'Driscoll M, Ruiz-Perez VL, Woods CG, Jeggo PA, Goodship JA (2003) A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat Genet 33: 497-501
    • (2003) Nat Genet , vol.33 , pp. 497-501
    • O'Driscoll, M.1    Ruiz-Perez, V.L.2    Woods, C.G.3    Jeggo, P.A.4    Goodship, J.A.5
  • 39
    • 0033358610 scopus 로고    scopus 로고
    • The mammalian Mre11-Rad50-nbs1 protein complex: Integration of functions in the cellular DNA-damage response
    • Petrini JH (1999) The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response. Am J Hum Genet 64: 1264-1269
    • (1999) Am J Hum Genet , vol.64 , pp. 1264-1269
    • Petrini, J.H.1
  • 40
    • 0036796260 scopus 로고    scopus 로고
    • DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein
    • Pichierri P, Averbeck D, Rosselli F (2002) DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein. Hum Mol Genet 11: 2531-2546
    • (2002) Hum Mol Genet , vol.11 , pp. 2531-2546
    • Pichierri, P.1    Averbeck, D.2    Rosselli, F.3
  • 43
    • 0030985116 scopus 로고    scopus 로고
    • The ATM gene and protein: Possible roles in genome surveillance, checkpoint controls and cellular defence against oxidative stress
    • Rotman G, Shiloh Y (1997) The ATM gene and protein: possible roles in genome surveillance, checkpoint controls and cellular defence against oxidative stress. Cancer Surv 29: 285-304
    • (1997) Cancer Surv , vol.29 , pp. 285-304
    • Rotman, G.1    Shiloh, Y.2
  • 45
    • 0031466618 scopus 로고    scopus 로고
    • Ataxia-telangiectasia and the Nijmegen breakage syndrome: Related disorders but genes apart
    • Shiloh Y (1997) Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart. Annu Rev Genet 31: 635-662
    • (1997) Annu Rev Genet , vol.31 , pp. 635-662
    • Shiloh, Y.1
  • 46
    • 0037350437 scopus 로고    scopus 로고
    • Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links
    • Sridharan D, Brown M, Lambert WC, McMahon LW, Lambert MW (2003) Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links. J Cell Sci 116: 823-835
    • (2003) J Cell Sci , vol.116 , pp. 823-835
    • Sridharan, D.1    Brown, M.2    Lambert, W.C.3    McMahon, L.W.4    Lambert, M.W.5
  • 47
    • 0026735882 scopus 로고
    • Cloning of cDNAs for Fanconi's anaemia by functional complementation
    • Strathdee CA, Gavish H, Shannon WR, Buchwald M (1992) Cloning of cDNAs for Fanconi's anaemia by functional complementation. Nature 358: 434
    • (1992) Nature , vol.358 , pp. 434
    • Strathdee, C.A.1    Gavish, H.2    Shannon, W.R.3    Buchwald, M.4
  • 49
    • 0030854142 scopus 로고    scopus 로고
    • Elevated homologous recombination activity in Fanconi anemia fibroblasts
    • Thyagarajan B, Campbell C (1997) Elevated homologous recombination activity in Fanconi anemia fibroblasts. J Biol Chem 272: 23328-23333
    • (1997) J Biol Chem , vol.272 , pp. 23328-23333
    • Thyagarajan, B.1    Campbell, C.2
  • 52
    • 0037069326 scopus 로고    scopus 로고
    • Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints
    • Zhao H, Watkins JL, Piwnica-Worms H (2002) Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints. Proc Natl Acad Sci USA 99: 14795-14800
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14795-14800
    • Zhao, H.1    Watkins, J.L.2    Piwnica-Worms, H.3
  • 54
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou L, Elledge SJ (2003) Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300: 1542-1548
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.