Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors

Biochemical and Biophysical Research Communications

Volumn 296, Issue 2, 2002, Pages 343-349

  Oehme, Felix ^a   Ellinghaus, Peter ^a   Kolkhof, Peter ^a   Smith, Timothy J ^b   Ramakrishnan, Shyam ^b   Hütter, Joachim ^a   Schramm, Matthias ^a   Flamme, Ingo ^a  

^a BAYER AG   (Germany)

^b Lion Bioscience   (United States)

Author keywords

EGLN; HIF; Hypoxia inducible transcription factor; Proline 4 hydroxylase; pVHL

Indexed keywords

ELONGATION FACTOR; HYPOXIA INDUCIBLE FACTOR 1; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; TRANSCRIPTION FACTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ASSAY; CELL NUCLEUS; CYTOPLASM; DEGRADATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; HYPOXIA; NUCLEOTIDE SEQUENCE; ORGAN; OXYGEN CONSUMPTION; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; TRANSACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; COS CELLS; GENES, REPORTER; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MOLECULAR SEQUENCE DATA; OXYGEN; PROCOLLAGEN-PROLINE DIOXYGENASE; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS;

EID: 0036391915     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)00862-8     Document Type: Article

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