-
1
-
-
33747199939
-
Proteolytic activation of PKCdelta contributes to oxidative- and ER-stress induced apoptotic cell death in prion-overexpressing mouse neural cells
-
[Abstract]
-
Anantharam V., Vorberg I., Choi C.J., Kanthasamy A., Richt J.A., Priola S.A., et al. Proteolytic activation of PKCdelta contributes to oxidative- and ER-stress induced apoptotic cell death in prion-overexpressing mouse neural cells. Proceedings of the 34th Annual Meeting of the Society for Neuroscience (2004) [Abstract]
-
(2004)
Proceedings of the 34th Annual Meeting of the Society for Neuroscience
-
-
Anantharam, V.1
Vorberg, I.2
Choi, C.J.3
Kanthasamy, A.4
Richt, J.A.5
Priola, S.A.6
-
4
-
-
5444270037
-
The persistence of long-term memory: a molecular approach to self-sustaining changes in learning-induced synaptic growth
-
Bailey C.H., Kandel E.R., and Si K. The persistence of long-term memory: a molecular approach to self-sustaining changes in learning-induced synaptic growth. Neuron 44 (2004) 49-57
-
(2004)
Neuron
, vol.44
, pp. 49-57
-
-
Bailey, C.H.1
Kandel, E.R.2
Si, K.3
-
5
-
-
0027257829
-
Microglia is a component of the prion protein amyloid plaque in the Gerstmann-Straussler-Scheinker syndrome
-
Barcikowska M., Liberski P.P., Boellaard J.W., Brown P., Gajdusek D.C., and Budka H. Microglia is a component of the prion protein amyloid plaque in the Gerstmann-Straussler-Scheinker syndrome. Acta Neuropathol (Berl) 85 (1993) 623-627
-
(1993)
Acta Neuropathol (Berl)
, vol.85
, pp. 623-627
-
-
Barcikowska, M.1
Liberski, P.P.2
Boellaard, J.W.3
Brown, P.4
Gajdusek, D.C.5
Budka, H.6
-
6
-
-
0020571465
-
Replication of the scrapie agent in hamster brain precedes neuronal vacuolation
-
Baringer J.R., Bowman K.A., and Prusiner SB. Replication of the scrapie agent in hamster brain precedes neuronal vacuolation. J Neuropathol Exp Neurol 42 (1983) 539-547
-
(1983)
J Neuropathol Exp Neurol
, vol.42
, pp. 539-547
-
-
Baringer, J.R.1
Bowman, K.A.2
Prusiner SB3
-
7
-
-
0015472801
-
Observations on oligodendrocyte degeneration, the resolution of status spongiosus and remyelination in cuprizone intoxication in mice
-
Blakemore W.F. Observations on oligodendrocyte degeneration, the resolution of status spongiosus and remyelination in cuprizone intoxication in mice. J Neurocytol 1 (1972) 413-426
-
(1972)
J Neurocytol
, vol.1
, pp. 413-426
-
-
Blakemore, W.F.1
-
8
-
-
18344391235
-
Copper (II) inhibits in vitro conversion of prion protein into amyloid fibrils
-
Bocharova O.V., Breydo L., Salnikov V.V., and Baskakov I.V. Copper (II) inhibits in vitro conversion of prion protein into amyloid fibrils. Biochemistry 44 (2005) 6776-6787
-
(2005)
Biochemistry
, vol.44
, pp. 6776-6787
-
-
Bocharova, O.V.1
Breydo, L.2
Salnikov, V.V.3
Baskakov, I.V.4
-
9
-
-
0014244579
-
Spread and scrapie by contact to goats and sheep
-
Brotherston J.G., Renwick C.C., Stamp J.T., Zlotnik I., and Pattison I.H. Spread and scrapie by contact to goats and sheep. J Comp Pathol 78 (1968) 9-17
-
(1968)
J Comp Pathol
, vol.78
, pp. 9-17
-
-
Brotherston, J.G.1
Renwick, C.C.2
Stamp, J.T.3
Zlotnik, I.4
Pattison, I.H.5
-
10
-
-
0141987922
-
Prion protein expression modulates neuronal copper content
-
Brown D.R. Prion protein expression modulates neuronal copper content. J Neurochem 87 (2003) 377-385
-
(2003)
J Neurochem
, vol.87
, pp. 377-385
-
-
Brown, D.R.1
-
11
-
-
0032169565
-
A prion protein expression and superoxide dismutase activity
-
Brown D.R., and Besinger A. A prion protein expression and superoxide dismutase activity. Biochem J 334 Pt 2 (1998) 423-429
-
(1998)
Biochem J
, vol.334
, Issue.PART 2
, pp. 423-429
-
-
Brown, D.R.1
Besinger, A.2
-
12
-
-
0141690230
-
Copper and zinc cause delivery of the prion protein from the plasma membrane to a subset of early endosomes and the Golgi
-
Brown D.R., and Harris D.A. Copper and zinc cause delivery of the prion protein from the plasma membrane to a subset of early endosomes and the Golgi. J Neurochem 87 (2003) 353-363
-
(2003)
J Neurochem
, vol.87
, pp. 353-363
-
-
Brown, D.R.1
Harris, D.A.2
-
13
-
-
0031194455
-
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity
-
Brown D.R., Schulz-Schaeffer W.J., Schmidt B., and Kretzschmar H.A. Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp Neurol 146 (1997) 104-112
-
(1997)
Exp Neurol
, vol.146
, pp. 104-112
-
-
Brown, D.R.1
Schulz-Schaeffer, W.J.2
Schmidt, B.3
Kretzschmar, H.A.4
-
14
-
-
0031444294
-
The cellular prion protein binds copper in vivo
-
Brown D.R., Qin K., Herms J.W., Madlung A., Manson J., Strome R., et al. The cellular prion protein binds copper in vivo. Nature 390 (1997) 684-687
-
(1997)
Nature
, vol.390
, pp. 684-687
-
-
Brown, D.R.1
Qin, K.2
Herms, J.W.3
Madlung, A.4
Manson, J.5
Strome, R.6
-
15
-
-
0031905248
-
Effects of copper on survival of prion protein knockout neurons and glia
-
Brown D.R., Schmidt B., and Kretzschmar H.A. Effects of copper on survival of prion protein knockout neurons and glia. J Neurochem 70 (1998) 1686-1693
-
(1998)
J Neurochem
, vol.70
, pp. 1686-1693
-
-
Brown, D.R.1
Schmidt, B.2
Kretzschmar, H.A.3
-
16
-
-
0034654304
-
Consequences of manganese replacement of copper for prion protein function and proteinase resistance
-
Brown D.R., Hafiz F., Glasssmith L.L., Wong B.S., Jones I.M., Clive C., et al. Consequences of manganese replacement of copper for prion protein function and proteinase resistance. EMBO J 19 (2000) 1180-1186
-
(2000)
EMBO J
, vol.19
, pp. 1180-1186
-
-
Brown, D.R.1
Hafiz, F.2
Glasssmith, L.L.3
Wong, B.S.4
Jones, I.M.5
Clive, C.6
-
17
-
-
0035158321
-
Antioxidant activity related to copper binding of native prion protein
-
Brown D.R., Clive C., and Haswell S.J. Antioxidant activity related to copper binding of native prion protein. J Neurochem 76 (2001) 69-76
-
(2001)
J Neurochem
, vol.76
, pp. 69-76
-
-
Brown, D.R.1
Clive, C.2
Haswell, S.J.3
-
18
-
-
0037080043
-
Lack of prion protein expression results in a neuronal phenotype sensitive to stress
-
Brown D.R., Nicholas R.S., and Canevari L. Lack of prion protein expression results in a neuronal phenotype sensitive to stress. J Neurosci Res 67 (2002) 211-224
-
(2002)
J Neurosci Res
, vol.67
, pp. 211-224
-
-
Brown, D.R.1
Nicholas, R.S.2
Canevari, L.3
-
19
-
-
23844471279
-
Blood infectivity, processing and screening tests in transmissible spongiform encephalopathy
-
Brown P. Blood infectivity, processing and screening tests in transmissible spongiform encephalopathy. Vox Sang 89 (2005) 63-70
-
(2005)
Vox Sang
, vol.89
, pp. 63-70
-
-
Brown, P.1
-
20
-
-
27744595782
-
Pathogenesis and transfusion risk of transmissible spongiform encephalopathies
-
Brown P. Pathogenesis and transfusion risk of transmissible spongiform encephalopathies. Dev Biol (Basel) 120 (2005) 27-33
-
(2005)
Dev Biol (Basel)
, vol.120
, pp. 27-33
-
-
Brown, P.1
-
21
-
-
0025786828
-
The human spongiform encephalopathies: kuru, Creutzfeldt-Jakob disease, and the Gerstmann-Straussler-Scheinker syndrome
-
Brown P., and Gajdusek D.C. The human spongiform encephalopathies: kuru, Creutzfeldt-Jakob disease, and the Gerstmann-Straussler-Scheinker syndrome. Curr Top Microbiol Immunol 172 (1991) 1-20
-
(1991)
Curr Top Microbiol Immunol
, vol.172
, pp. 1-20
-
-
Brown, P.1
Gajdusek, D.C.2
-
22
-
-
0028876473
-
Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases)
-
Budka H., Aguzzi A., Brown P., Brucher J.M., Bugiani O., Gullotta F., et al. Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases). Brain Pathol 5 (1995) 459-466
-
(1995)
Brain Pathol
, vol.5
, pp. 459-466
-
-
Budka, H.1
Aguzzi, A.2
Brown, P.3
Brucher, J.M.4
Bugiani, O.5
Gullotta, F.6
-
24
-
-
0037343044
-
Stability and Cu(II) binding of prion protein variants related to inherited human prion diseases
-
Cereghetti G.M., Schweiger A., Glockshuber R., and Van Doorslaer S. Stability and Cu(II) binding of prion protein variants related to inherited human prion diseases. Biophys J 84 (2003) 1985-1997
-
(2003)
Biophys J
, vol.84
, pp. 1985-1997
-
-
Cereghetti, G.M.1
Schweiger, A.2
Glockshuber, R.3
Van Doorslaer, S.4
-
25
-
-
0029877723
-
Fatal insomnia in a case of familial Creutzfeldt-Jakob disease with the codon 200(Lys) mutation
-
Chapman J., Arlazoroff A., Goldfarb L.G., Cervenakova L., Neufeld M.Y., Werber E., et al. Fatal insomnia in a case of familial Creutzfeldt-Jakob disease with the codon 200(Lys) mutation. Neurology 46 (1996) 758-761
-
(1996)
Neurology
, vol.46
, pp. 758-761
-
-
Chapman, J.1
Arlazoroff, A.2
Goldfarb, L.G.3
Cervenakova, L.4
Neufeld, M.Y.5
Werber, E.6
-
26
-
-
0019060311
-
Biohazards of investigations on the transmissible spongiform encephalopathies
-
Chatigny M.A., and Prusiner S.B. Biohazards of investigations on the transmissible spongiform encephalopathies. Rev Infect Dis 2 (1980) 713-724
-
(1980)
Rev Infect Dis
, vol.2
, pp. 713-724
-
-
Chatigny, M.A.1
Prusiner, S.B.2
-
27
-
-
0345505687
-
Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival
-
Chen S., Mange A., Dong L., Lehmann S., and Schachner M. Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival. Mol Cell Neurosci 22 (2003) 227-233
-
(2003)
Mol Cell Neurosci
, vol.22
, pp. 227-233
-
-
Chen, S.1
Mange, A.2
Dong, L.3
Lehmann, S.4
Schachner, M.5
-
28
-
-
0036645677
-
Cellular prion protein transduces neuroprotective signals
-
Chiarini L.B., Freitas A.R., Zanata S.M., Brentani R.R., Martins V.R., and Linden R. Cellular prion protein transduces neuroprotective signals. EMBO J 21 (2002) 3317-3326
-
(2002)
EMBO J
, vol.21
, pp. 3317-3326
-
-
Chiarini, L.B.1
Freitas, A.R.2
Zanata, S.M.3
Brentani, R.R.4
Martins, V.R.5
Linden, R.6
-
29
-
-
3242692543
-
Investigation of trace elements in soil as risk factors in the epidemiology of scrapie
-
Chihota C.M., Gravenor M.B., and Baylis M. Investigation of trace elements in soil as risk factors in the epidemiology of scrapie. Vet Rec 154 (2004) 809-813
-
(2004)
Vet Rec
, vol.154
, pp. 809-813
-
-
Chihota, C.M.1
Gravenor, M.B.2
Baylis, M.3
-
30
-
-
0141987860
-
The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg
-
Ciechanover A., and Brundin P. The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg. Neuron 40 (2003) 427-446
-
(2003)
Neuron
, vol.40
, pp. 427-446
-
-
Ciechanover, A.1
Brundin, P.2
-
31
-
-
0028338441
-
Structural clues to prion replication
-
Cohen F.E., Pan K.M., Huang Z., Baldwin M., Fletterick R.J., and Prusiner S.B. Structural clues to prion replication. Science 264 (1994) 530-531
-
(1994)
Science
, vol.264
, pp. 530-531
-
-
Cohen, F.E.1
Pan, K.M.2
Huang, Z.3
Baldwin, M.4
Fletterick, R.J.5
Prusiner, S.B.6
-
32
-
-
0034916581
-
Prion diseases of humans and animals: their causes and molecular basis
-
Collinge J. Prion diseases of humans and animals: their causes and molecular basis. Annu Rev Neurosci 24 (2001) 519-550
-
(2001)
Annu Rev Neurosci
, vol.24
, pp. 519-550
-
-
Collinge, J.1
-
34
-
-
0024474822
-
Diagnosis of Gerstmann-Straussler syndrome in familial dementia with prion protein gene analysis
-
Collinge J., Harding A.E., Owen F., Poulter M., Lofthouse R., Boughey A.M., et al. Diagnosis of Gerstmann-Straussler syndrome in familial dementia with prion protein gene analysis. Lancet 2 (1989) 15-17
-
(1989)
Lancet
, vol.2
, pp. 15-17
-
-
Collinge, J.1
Harding, A.E.2
Owen, F.3
Poulter, M.4
Lofthouse, R.5
Boughey, A.M.6
-
35
-
-
0347355571
-
Memory, synaptic translation, and prions?
-
Darnell R.B. Memory, synaptic translation, and prions?. Cell 115 (2003) 767-768
-
(2003)
Cell
, vol.115
, pp. 767-768
-
-
Darnell, R.B.1
-
36
-
-
0028798626
-
Prion protein transgenes and the neuropathology in prion diseases
-
DeArmond S.J., and Prusiner S.B. Prion protein transgenes and the neuropathology in prion diseases. Brain Pathol 5 (1995) 77-89
-
(1995)
Brain Pathol
, vol.5
, pp. 77-89
-
-
DeArmond, S.J.1
Prusiner, S.B.2
-
37
-
-
3042629535
-
The structure function relationship for the prion protein
-
Deignan M.E., Prior M., Stuart L.E., Comerford E.J., and McMahon H.E. The structure function relationship for the prion protein. J Alzheimers Dis 6 (2004) 283-289
-
(2004)
J Alzheimers Dis
, vol.6
, pp. 283-289
-
-
Deignan, M.E.1
Prior, M.2
Stuart, L.E.3
Comerford, E.J.4
McMahon, H.E.5
-
38
-
-
26944491123
-
Copper (II) interaction with unstructured prion domain outside the octarepeat region: speciation, stability, and binding details of copper (II) complexes with PrP106-126 peptides
-
Di Natale G., Grasso G., Impellizzeri G., La Mendola D., Micera G., Mihala N., et al. Copper (II) interaction with unstructured prion domain outside the octarepeat region: speciation, stability, and binding details of copper (II) complexes with PrP106-126 peptides. Inorg Chem 44 (2005) 7214-7225
-
(2005)
Inorg Chem
, vol.44
, pp. 7214-7225
-
-
Di Natale, G.1
Grasso, G.2
Impellizzeri, G.3
La Mendola, D.4
Micera, G.5
Mihala, N.6
-
41
-
-
19544368647
-
Increased iron-induced oxidative stress and toxicity in scrapie-infected neuroblastoma cells
-
Fernaeus S., and Land T. Increased iron-induced oxidative stress and toxicity in scrapie-infected neuroblastoma cells. Neurosci Lett 382 (2005) 217-220
-
(2005)
Neurosci Lett
, vol.382
, pp. 217-220
-
-
Fernaeus, S.1
Land, T.2
-
42
-
-
24644450571
-
Increased susceptibility to oxidative stress in scrapie-infected neuroblastoma cells is associated with intracellular iron status
-
Fernaeus S., Reis K., Bedecs K., and Land T. Increased susceptibility to oxidative stress in scrapie-infected neuroblastoma cells is associated with intracellular iron status. Neurosci Lett 389 (2005) 133-136
-
(2005)
Neurosci Lett
, vol.389
, pp. 133-136
-
-
Fernaeus, S.1
Reis, K.2
Bedecs, K.3
Land, T.4
-
44
-
-
15744395826
-
Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations
-
Fioriti L., Dossena S., Stewart L.R., Stewart R.S., Harris D.A., Forloni G., et al. Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations. J Biol Chem 280 (2005) 11320-11328
-
(2005)
J Biol Chem
, vol.280
, pp. 11320-11328
-
-
Fioriti, L.1
Dossena, S.2
Stewart, L.R.3
Stewart, R.S.4
Harris, D.A.5
Forloni, G.6
-
45
-
-
0035174927
-
Transmission of scrapie by steel-surface-bound prions
-
Flechsig E., Hegyi I., Enari M., Schwarz P., Collinge J., and Weissmann C. Transmission of scrapie by steel-surface-bound prions. Mol Med 7 (2001) 679-684
-
(2001)
Mol Med
, vol.7
, pp. 679-684
-
-
Flechsig, E.1
Hegyi, I.2
Enari, M.3
Schwarz, P.4
Collinge, J.5
Weissmann, C.6
-
46
-
-
12444341883
-
Interaction of the human prion PrP(106-126) sequence with copper (II), manganese (II), and zinc (II): NMR and EPR studies
-
Gaggelli E., Bernardi F., Molteni E., Pogni R., Valensin D., Valensin G., et al. Interaction of the human prion PrP(106-126) sequence with copper (II), manganese (II), and zinc (II): NMR and EPR studies. J Am Chem Soc 127 (2005) 996-1006
-
(2005)
J Am Chem Soc
, vol.127
, pp. 996-1006
-
-
Gaggelli, E.1
Bernardi, F.2
Molteni, E.3
Pogni, R.4
Valensin, D.5
Valensin, G.6
-
47
-
-
0027388993
-
Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity
-
Gasset M., Baldwin M.A., Fletterick R.J., and Prusiner S.B. Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity. Proc Natl Acad Sci USA 90 (1993) 1-5
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1-5
-
-
Gasset, M.1
Baldwin, M.A.2
Fletterick, R.J.3
Prusiner, S.B.4
-
48
-
-
0026705377
-
Prion protein preamyloid and amyloid deposits in Gerstmann-Straussler-Scheinker disease, Indiana kindred
-
Giaccone G., Verga L., Bugiani O., Frangione B., Serban D., Prusiner S.B., et al. Prion protein preamyloid and amyloid deposits in Gerstmann-Straussler-Scheinker disease, Indiana kindred. Proc Natl Acad Sci USA 89 (1992) 9349-9353
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9349-9353
-
-
Giaccone, G.1
Verga, L.2
Bugiani, O.3
Frangione, B.4
Serban, D.5
Prusiner, S.B.6
-
49
-
-
0022363761
-
Clinical and pathological features and laboratory confirmation of Creutzfeldt-Jakob disease in a recipient of pituitary-derived human growth hormone
-
Gibbs Jr. C.J., Joy A., Heffner R., Franko M., Miyazaki M., Asher D.M., et al. Clinical and pathological features and laboratory confirmation of Creutzfeldt-Jakob disease in a recipient of pituitary-derived human growth hormone. New Engl J Med 313 (1985) 734-738
-
(1985)
New Engl J Med
, vol.313
, pp. 734-738
-
-
Gibbs Jr., C.J.1
Joy, A.2
Heffner, R.3
Franko, M.4
Miyazaki, M.5
Asher, D.M.6
-
50
-
-
27644529810
-
Mouse brain synaptosomes accumulate copper-67 efficiently by two distinct processes independent of cellular prion protein
-
Giese A., Buchholz M., Herms J., and Kretzschmar H.A. Mouse brain synaptosomes accumulate copper-67 efficiently by two distinct processes independent of cellular prion protein. J Mol Neurosci 27 (2005) 347-354
-
(2005)
J Mol Neurosci
, vol.27
, pp. 347-354
-
-
Giese, A.1
Buchholz, M.2
Herms, J.3
Kretzschmar, H.A.4
-
51
-
-
0024467653
-
Mutations in familial Creutzfeldt-Jakob disease and Gerstmann-Straussler-Scheinker's syndrome
-
Goldgaber D., Goldfarb L.G., Brown P., Asher D.M., Brown W.T., Lin S., et al. Mutations in familial Creutzfeldt-Jakob disease and Gerstmann-Straussler-Scheinker's syndrome. Exp Neurol 106 (1989) 204-206
-
(1989)
Exp Neurol
, vol.106
, pp. 204-206
-
-
Goldgaber, D.1
Goldfarb, L.G.2
Brown, P.3
Asher, D.M.4
Brown, W.T.5
Lin, S.6
-
52
-
-
0027267948
-
Fibrils in brain of Rocky Mountain elk with chronic wasting disease contain scrapie amyloid
-
Guiroy D.C., Williams E.S., Song K.J., Yanagihara R., and Gajdusek D.C. Fibrils in brain of Rocky Mountain elk with chronic wasting disease contain scrapie amyloid. Acta Neuropathol (Berl) 86 (1993) 77-80
-
(1993)
Acta Neuropathol (Berl)
, vol.86
, pp. 77-80
-
-
Guiroy, D.C.1
Williams, E.S.2
Song, K.J.3
Yanagihara, R.4
Gajdusek, D.C.5
-
53
-
-
24944491725
-
Copper binding is the governing determinant of prion protein turnover
-
Haigh C.L., Edwards K., and Brown D.R. Copper binding is the governing determinant of prion protein turnover. Mol Cell Neurosci 30 (2005) 186-196
-
(2005)
Mol Cell Neurosci
, vol.30
, pp. 186-196
-
-
Haigh, C.L.1
Edwards, K.2
Brown, D.R.3
-
54
-
-
0031053453
-
Pathology and immunocytochemistry of a kuru brain
-
Hainfellner J.A., Liberski P.P., Guiroy D.C., Cervenakova L., Brown P., Gajdusek D.C., et al. Pathology and immunocytochemistry of a kuru brain. Brain Pathol 7 (1997) 547-553
-
(1997)
Brain Pathol
, vol.7
, pp. 547-553
-
-
Hainfellner, J.A.1
Liberski, P.P.2
Guiroy, D.C.3
Cervenakova, L.4
Brown, P.5
Gajdusek, D.C.6
-
55
-
-
0026044686
-
Familial Creutzfeldt-Jakob disease in Finland: epidemiological, clinical, pathological and molecular genetic studies
-
Haltia M., Kovanen J., Goldfarb L.G., Brown P., and Gajdusek D.C. Familial Creutzfeldt-Jakob disease in Finland: epidemiological, clinical, pathological and molecular genetic studies. Eur J Epidemiol 7 (1991) 494-500
-
(1991)
Eur J Epidemiol
, vol.7
, pp. 494-500
-
-
Haltia, M.1
Kovanen, J.2
Goldfarb, L.G.3
Brown, P.4
Gajdusek, D.C.5
-
56
-
-
4143152945
-
Transmission of sheep scrapie to elk (Cervus elaphus nelsoni) by intracerebral inoculation: final outcome of the experiment
-
Hamir A.N., Miller J.M., Cutlip R.C., Kunkle R.A., Jenny A.L., Stack M.J., et al. Transmission of sheep scrapie to elk (Cervus elaphus nelsoni) by intracerebral inoculation: final outcome of the experiment. J Vet Diagn Invest 16 (2004) 316-321
-
(2004)
J Vet Diagn Invest
, vol.16
, pp. 316-321
-
-
Hamir, A.N.1
Miller, J.M.2
Cutlip, R.C.3
Kunkle, R.A.4
Jenny, A.L.5
Stack, M.J.6
-
57
-
-
19944412183
-
Experimental transmission of chronic wasting disease agent from mule deer to cattle by the intracerebral route
-
Hamir A.N., Kunkle R.A., Cutlip R.C., Miller J.M., O'Rourke K.I., Williams E.S., et al. Experimental transmission of chronic wasting disease agent from mule deer to cattle by the intracerebral route. J Vet Diagn Invest 17 (2005) 276-281
-
(2005)
J Vet Diagn Invest
, vol.17
, pp. 276-281
-
-
Hamir, A.N.1
Kunkle, R.A.2
Cutlip, R.C.3
Miller, J.M.4
O'Rourke, K.I.5
Williams, E.S.6
-
58
-
-
0033570367
-
Evidence of presynaptic location and function of the prion protein
-
Herms J., Tings T., Gall S., Madlung A., Giese A., Siebert H., et al. Evidence of presynaptic location and function of the prion protein. J Neurosci 19 (1999) 8866-8875
-
(1999)
J Neurosci
, vol.19
, pp. 8866-8875
-
-
Herms, J.1
Tings, T.2
Gall, S.3
Madlung, A.4
Giese, A.5
Siebert, H.6
-
59
-
-
0345714734
-
Copper binding to PrPC may inhibit prion disease propagation
-
Hijazi N., Shaked Y., Rosenmann H., Ben-Hur T., and Gabizon R. Copper binding to PrPC may inhibit prion disease propagation. Brain Res 993 (2003) 192-200
-
(2003)
Brain Res
, vol.993
, pp. 192-200
-
-
Hijazi, N.1
Shaked, Y.2
Rosenmann, H.3
Ben-Hur, T.4
Gabizon, R.5
-
60
-
-
0141849465
-
Subclinical prion infection in humans and animals
-
Hill A.F., and Collinge J. Subclinical prion infection in humans and animals. Br Med Bull 66 (2003) 161-170
-
(2003)
Br Med Bull
, vol.66
, pp. 161-170
-
-
Hill, A.F.1
Collinge, J.2
-
61
-
-
0033573778
-
Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples
-
Hill A.F., Butterworth R.J., Joiner S., Jackson G., Rossor M.N., Thomas D.J., et al. Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 353 (1999) 183-189
-
(1999)
Lancet
, vol.353
, pp. 183-189
-
-
Hill, A.F.1
Butterworth, R.J.2
Joiner, S.3
Jackson, G.4
Rossor, M.N.5
Thomas, D.J.6
-
62
-
-
0034730170
-
Species-barrier-independent prion replication in apparently resistant species
-
Hill A.F., Joiner S., Linehan J., Desbruslais M., Lantos P.L., and Collinge J. Species-barrier-independent prion replication in apparently resistant species. Proc Natl Acad Sci USA 97 (2000) 10248-10253
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10248-10253
-
-
Hill, A.F.1
Joiner, S.2
Linehan, J.3
Desbruslais, M.4
Lantos, P.L.5
Collinge, J.6
-
63
-
-
0032948013
-
Risk of prion disease transmission from ocular donor tissue transplantation
-
Hogan R.N., Brown P., Heck E., and Cavanagh H.D. Risk of prion disease transmission from ocular donor tissue transplantation. Cornea 18 (1999) 2-11
-
(1999)
Cornea
, vol.18
, pp. 2-11
-
-
Hogan, R.N.1
Brown, P.2
Heck, E.3
Cavanagh, H.D.4
-
64
-
-
0034705020
-
Interactions between heterologous forms of prion protein: binding, inhibition of conversion, and species barriers
-
Horiuchi M., Priola S.A., Chabry J., and Caughey B. Interactions between heterologous forms of prion protein: binding, inhibition of conversion, and species barriers. Proc Natl Acad Sci USA 97 (2000) 5836-5841
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5836-5841
-
-
Horiuchi, M.1
Priola, S.A.2
Chabry, J.3
Caughey, B.4
-
65
-
-
0028844207
-
Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: structural studies using synthetic peptides
-
Hornshaw M.P., McDermott J.R., Candy J.M., and Lakey J.H. Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: structural studies using synthetic peptides. Biochem Biophys Res Commun 214 (1995) 993-999
-
(1995)
Biochem Biophys Res Commun
, vol.214
, pp. 993-999
-
-
Hornshaw, M.P.1
McDermott, J.R.2
Candy, J.M.3
Lakey, J.H.4
-
66
-
-
0025995471
-
Molecular genetics and transgenic model of Gerstmann-Straussler-Scheinker disease
-
Hsiao K., and Prusiner S.B. Molecular genetics and transgenic model of Gerstmann-Straussler-Scheinker disease. Alzheimer Dis Assoc Disord 5 (1991) 155-162
-
(1991)
Alzheimer Dis Assoc Disord
, vol.5
, pp. 155-162
-
-
Hsiao, K.1
Prusiner, S.B.2
-
67
-
-
0024519771
-
Linkage of a prion protein missense variant to Gerstmann-Straussler syndrome
-
Hsiao K., Baker H.F., Crow T.J., Poulter M., Owen F., Terwilliger J.D., et al. Linkage of a prion protein missense variant to Gerstmann-Straussler syndrome. Nature 338 (1989) 342-345
-
(1989)
Nature
, vol.338
, pp. 342-345
-
-
Hsiao, K.1
Baker, H.F.2
Crow, T.J.3
Poulter, M.4
Owen, F.5
Terwilliger, J.D.6
-
68
-
-
0026849947
-
Mutant prion proteins in Gerstmann-Straussler-Scheinker disease with neurofibrillary tangles
-
Hsiao K., Dlouhy S.R., Farlow M.R., Cass C., Da Costa M., Conneally P.M., et al. Mutant prion proteins in Gerstmann-Straussler-Scheinker disease with neurofibrillary tangles. Nat Genet 1 (1992) 68-71
-
(1992)
Nat Genet
, vol.1
, pp. 68-71
-
-
Hsiao, K.1
Dlouhy, S.R.2
Farlow, M.R.3
Cass, C.4
Da Costa, M.5
Conneally, P.M.6
-
69
-
-
0030342679
-
Scrapie prions: a three-dimensional model of an infectious fragment
-
Huang Z., Prusiner S.B., and Cohen F.E. Scrapie prions: a three-dimensional model of an infectious fragment. Fold Des 1 (1996) 13-19
-
(1996)
Fold Des
, vol.1
, pp. 13-19
-
-
Huang, Z.1
Prusiner, S.B.2
Cohen, F.E.3
-
70
-
-
0029656091
-
Structures of prion proteins and conformational models for prion diseases
-
Huang Z., Prusiner S.B., and Cohen F.E. Structures of prion proteins and conformational models for prion diseases. Curr Top Microbiol Immunol 207 (1996) 49-67
-
(1996)
Curr Top Microbiol Immunol
, vol.207
, pp. 49-67
-
-
Huang, Z.1
Prusiner, S.B.2
Cohen, F.E.3
-
71
-
-
0141717118
-
No superoxide dismutase activity of cellular prion protein in vivo
-
Hutter G., Heppner F.L., and Aguzzi A. No superoxide dismutase activity of cellular prion protein in vivo. Biol Chem 384 (2003) 1279-1285
-
(2003)
Biol Chem
, vol.384
, pp. 1279-1285
-
-
Hutter, G.1
Heppner, F.L.2
Aguzzi, A.3
-
72
-
-
0035902531
-
Location and properties of metal-binding sites on the human prion protein
-
Jackson G.S., Murray I., Hosszu L.L., Gibbs N., Waltho J.P., Clarke A.R., et al. Location and properties of metal-binding sites on the human prion protein. Proc Natl Acad Sci USA 98 (2001) 8531-8535
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8531-8535
-
-
Jackson, G.S.1
Murray, I.2
Hosszu, L.L.3
Gibbs, N.4
Waltho, J.P.5
Clarke, A.R.6
-
73
-
-
0035838471
-
Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126
-
Jobling M.F., Huang X., Stewart L.R., Barnham K.J., Curtain C., Volitakis I., et al. Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126. Biochemistry 40 (2001) 8073-8084
-
(2001)
Biochemistry
, vol.40
, pp. 8073-8084
-
-
Jobling, M.F.1
Huang, X.2
Stewart, L.R.3
Barnham, K.J.4
Curtain, C.5
Volitakis, I.6
-
74
-
-
3542999252
-
2+ coordination by His96 and His111 induces beta-sheet formation in the unstructured amyloidogenic region of the prion protein
-
2+ coordination by His96 and His111 induces beta-sheet formation in the unstructured amyloidogenic region of the prion protein. J Biol Chem 279 (2004) 32018-32027
-
(2004)
J Biol Chem
, vol.279
, pp. 32018-32027
-
-
Jones, C.E.1
Abdelraheim, S.R.2
Brown, D.R.3
Viles, J.H.4
-
76
-
-
33747178745
-
Recombinant prion protein does not possess superoxide dismutase activity
-
Jones S., Batchelor M., Bhelt D., Clarke A.R., Collinge J., and Jackson G.S. Recombinant prion protein does not possess superoxide dismutase activity. Biochem J (2005)
-
(2005)
Biochem J
-
-
Jones, S.1
Batchelor, M.2
Bhelt, D.3
Clarke, A.R.4
Collinge, J.5
Jackson, G.S.6
-
77
-
-
0031586212
-
Molecular properties of complexes formed between the prion protein and synthetic peptides
-
Kaneko K., Wille H., Mehlhorn I., Zhang H., Ball H., Cohen F.E., et al. Molecular properties of complexes formed between the prion protein and synthetic peptides. J Mol Biol 270 (1997) 574-586
-
(1997)
J Mol Biol
, vol.270
, pp. 574-586
-
-
Kaneko, K.1
Wille, H.2
Mehlhorn, I.3
Zhang, H.4
Ball, H.5
Cohen, F.E.6
-
78
-
-
1942531594
-
Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice
-
Kang S.C., Brown D.R., Whiteman M., Li R., Pan T., Perry G., et al. Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice. J Pathol 203 (2004) 603-608
-
(2004)
J Pathol
, vol.203
, pp. 603-608
-
-
Kang, S.C.1
Brown, D.R.2
Whiteman, M.3
Li, R.4
Pan, T.5
Perry, G.6
-
79
-
-
18144362825
-
Effect of transition metals (Mn, Cu, Fe) and deoxycholic acid (DA) on the conversion of PrPC to PrPres
-
Kim N.H., Choi J.K., Jeong B.H., Kim J.I., Kwon M.S., Carp R.I., et al. Effect of transition metals (Mn, Cu, Fe) and deoxycholic acid (DA) on the conversion of PrPC to PrPres. FASEB J 19 (2005) 783-785
-
(2005)
FASEB J
, vol.19
, pp. 783-785
-
-
Kim, N.H.1
Choi, J.K.2
Jeong, B.H.3
Kim, J.I.4
Kwon, M.S.5
Carp, R.I.6
-
80
-
-
0017153716
-
The effects of cuprizone toxicity on the incubation period of scrapie in mice
-
Kimberlin R.H., and Millson G.C. The effects of cuprizone toxicity on the incubation period of scrapie in mice. J Comp Pathol 86 (1976) 489-496
-
(1976)
J Comp Pathol
, vol.86
, pp. 489-496
-
-
Kimberlin, R.H.1
Millson, G.C.2
-
81
-
-
4544335297
-
Cellular prion protein acquires resistance to proteolytic degradation following copper ion binding
-
Kuczius T., Buschmann A., Zhang W., Karch H., Becker K., Peters G., et al. Cellular prion protein acquires resistance to proteolytic degradation following copper ion binding. Biol Chem 385 (2004) 739-747
-
(2004)
Biol Chem
, vol.385
, pp. 739-747
-
-
Kuczius, T.1
Buschmann, A.2
Zhang, W.3
Karch, H.4
Becker, K.5
Peters, G.6
-
82
-
-
0141515196
-
Putative functions of PrP(C)
-
Lasmezas C.I. Putative functions of PrP(C). Br Med Bull 66 (2003) 61-70
-
(2003)
Br Med Bull
, vol.66
, pp. 61-70
-
-
Lasmezas, C.I.1
-
83
-
-
0026605853
-
Lysosomes as key organelles in the pathogenesis of prion encephalopathies
-
Laszlo L., Lowe J., Self T., Kenward N., Landon M., McBride T., et al. Lysosomes as key organelles in the pathogenesis of prion encephalopathies. J Pathol 166 (1992) 333-341
-
(1992)
J Pathol
, vol.166
, pp. 333-341
-
-
Laszlo, L.1
Lowe, J.2
Self, T.3
Kenward, N.4
Landon, M.5
McBride, T.6
-
84
-
-
13844321726
-
Strain-specified characteristics of mouse synthetic prions
-
Legname G., Nguyen H.O., Baskakov I.V., Cohen F.E., Dearmond S.J., and Prusiner S.B. Strain-specified characteristics of mouse synthetic prions. Proc Natl Acad Sci USA 102 (2005) 2168-2173
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2168-2173
-
-
Legname, G.1
Nguyen, H.O.2
Baskakov, I.V.3
Cohen, F.E.4
Dearmond, S.J.5
Prusiner, S.B.6
-
86
-
-
5444262992
-
Kuru: a half-opened window onto the landscape of neurodegenerative diseases
-
Liberski P.P., and Brown P. Kuru: a half-opened window onto the landscape of neurodegenerative diseases. Folia Neuropathol 42 Suppl. A (2004) 3-14
-
(2004)
Folia Neuropathol
, vol.42
, Issue.SUPPL. A
, pp. 3-14
-
-
Liberski, P.P.1
Brown, P.2
-
87
-
-
0026377074
-
Creutzfeldt-Jakob disease (CJD) of a short duration with prion protein (PrP) plaques
-
Liberski P.P., Kwiecinski H., Barcikowska M., Mirecka B., Kulczycki J., Kida E., et al. Creutzfeldt-Jakob disease (CJD) of a short duration with prion protein (PrP) plaques. Patol Pol 42 (1991) 115-118
-
(1991)
Patol Pol
, vol.42
, pp. 115-118
-
-
Liberski, P.P.1
Kwiecinski, H.2
Barcikowska, M.3
Mirecka, B.4
Kulczycki, J.5
Kida, E.6
-
88
-
-
0037195647
-
Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol
-
Ma J., Wollmann R., and Lindquist S. Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol. Science 298 (2002) 1781-1785
-
(2002)
Science
, vol.298
, pp. 1781-1785
-
-
Ma, J.1
Wollmann, R.2
Lindquist, S.3
-
89
-
-
0035993235
-
The biology of the cellular prion protein
-
Martins V.R., and Brentani R.R. The biology of the cellular prion protein. Neurochem Int 41 (2002) 353-355
-
(2002)
Neurochem Int
, vol.41
, pp. 353-355
-
-
Martins, V.R.1
Brentani, R.R.2
-
90
-
-
0035350548
-
Insights into the physiological function of cellular prion protein
-
Martins V.R., Mercadante A.F., Cabral A.L., Freitas A.R., and Castro R.M. Insights into the physiological function of cellular prion protein. Braz J Med Biol Res 34 (2001) 585-595
-
(2001)
Braz J Med Biol Res
, vol.34
, pp. 585-595
-
-
Martins, V.R.1
Mercadante, A.F.2
Cabral, A.L.3
Freitas, A.R.4
Castro, R.M.5
-
92
-
-
10644241804
-
Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine
-
Mishra R.S., Basu S., Gu Y., Luo X., Zou W.Q., Mishra R., et al. Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine. J Neurosci 24 (2004) 11280-11290
-
(2004)
J Neurosci
, vol.24
, pp. 11280-11290
-
-
Mishra, R.S.1
Basu, S.2
Gu, Y.3
Luo, X.4
Zou, W.Q.5
Mishra, R.6
-
93
-
-
20544450600
-
Copper reduction by the octapeptide repeat region of prion protein: pH dependence and implications in cellular copper uptake
-
Miura T., Sasaki S., Toyama A., and Takeuchi H. Copper reduction by the octapeptide repeat region of prion protein: pH dependence and implications in cellular copper uptake. Biochemistry 44 (2005) 8712-8720
-
(2005)
Biochemistry
, vol.44
, pp. 8712-8720
-
-
Miura, T.1
Sasaki, S.2
Toyama, A.3
Takeuchi, H.4
-
94
-
-
0034665847
-
Signal transduction through prion protein
-
Mouillet-Richard S., Ermonval M., Chebassier C., Laplanche J.L., Lehmann S., Launay J.M., et al. Signal transduction through prion protein. Science 289 (2000) 1925-1928
-
(2000)
Science
, vol.289
, pp. 1925-1928
-
-
Mouillet-Richard, S.1
Ermonval, M.2
Chebassier, C.3
Laplanche, J.L.4
Lehmann, S.5
Launay, J.M.6
-
95
-
-
19544380185
-
Separation of native prion protein (PrP) glycoforms by copper-binding using immobilized metal affinity chromatography (IMAC)
-
Muller H., Strom A., Hunsmann G., and Stuke A.W. Separation of native prion protein (PrP) glycoforms by copper-binding using immobilized metal affinity chromatography (IMAC). Biochem J 388 (2005) 371-378
-
(2005)
Biochem J
, vol.388
, pp. 371-378
-
-
Muller, H.1
Strom, A.2
Hunsmann, G.3
Stuke, A.W.4
-
96
-
-
0028925377
-
Prion protein peptides induce alpha-helix to beta-sheet conformational transitions
-
Nguyen J., Baldwin M.A., Cohen F.E., and Prusiner S.B. Prion protein peptides induce alpha-helix to beta-sheet conformational transitions. Biochemistry 34 (1995) 4186-4192
-
(1995)
Biochemistry
, vol.34
, pp. 4186-4192
-
-
Nguyen, J.1
Baldwin, M.A.2
Cohen, F.E.3
Prusiner, S.B.4
-
97
-
-
4444266619
-
Cellular prion protein regulates intracellular hydrogen peroxide level and prevents copper-induced apoptosis
-
Nishimura T., Sakudo A., Nakamura I., Lee D.C., Taniuchi Y., Saeki K., et al. Cellular prion protein regulates intracellular hydrogen peroxide level and prevents copper-induced apoptosis. Biochem Biophys Res Commun 323 (2004) 218-222
-
(2004)
Biochem Biophys Res Commun
, vol.323
, pp. 218-222
-
-
Nishimura, T.1
Sakudo, A.2
Nakamura, I.3
Lee, D.C.4
Taniuchi, Y.5
Saeki, K.6
-
98
-
-
4644331407
-
Ionic strength and transition metals control PrPSc protease resistance and conversion-inducing activity
-
Nishina K., Jenks S., and Supattapone S. Ionic strength and transition metals control PrPSc protease resistance and conversion-inducing activity. J Biol Chem 279 (2004) 40788-40794
-
(2004)
J Biol Chem
, vol.279
, pp. 40788-40794
-
-
Nishina, K.1
Jenks, S.2
Supattapone, S.3
-
99
-
-
0017129298
-
Biochemistry of copper
-
O'Dell B.L. Biochemistry of copper. Med Clin North Am 60 (1976) 687-703
-
(1976)
Med Clin North Am
, vol.60
, pp. 687-703
-
-
O'Dell, B.L.1
-
100
-
-
0037355742
-
Copper reduction by copper binding proteins and its relation to neurodegenerative diseases
-
Opazo C., Barria M.I., Ruiz F.H., and Inestrosa N.C. Copper reduction by copper binding proteins and its relation to neurodegenerative diseases. Biometals 16 (2003) 91-98
-
(2003)
Biometals
, vol.16
, pp. 91-98
-
-
Opazo, C.1
Barria, M.I.2
Ruiz, F.H.3
Inestrosa, N.C.4
-
101
-
-
0024530897
-
Insertion in prion protein gene in familial Creutzfeldt-Jakob disease
-
Owen F., Poulter M., Lofthouse R., Collinge J., Crow T.J., Risby D., et al. Insertion in prion protein gene in familial Creutzfeldt-Jakob disease. Lancet 1 (1989) 51-52
-
(1989)
Lancet
, vol.1
, pp. 51-52
-
-
Owen, F.1
Poulter, M.2
Lofthouse, R.3
Collinge, J.4
Crow, T.J.5
Risby, D.6
-
103
-
-
0027270270
-
Deletions in the prion protein gene are not associated with CJD
-
Palmer M.S., Mahal S.P., Campbell T.A., Hill A.F., Sidle K.C., Laplanche J.L., et al. Deletions in the prion protein gene are not associated with CJD. Hum Mol Genet 2 (1993) 541-544
-
(1993)
Hum Mol Genet
, vol.2
, pp. 541-544
-
-
Palmer, M.S.1
Mahal, S.P.2
Campbell, T.A.3
Hill, A.F.4
Sidle, K.C.5
Laplanche, J.L.6
-
104
-
-
26444509890
-
The prion gene is associated with human long-term memory
-
Papassotiropoulos A., Wollmer M.A., Aguzzi A., Hock C., Nitsch R.M., and de Quervain D.J. The prion gene is associated with human long-term memory. Hum Mol Genet 14 (2005) 2241-2246
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2241-2246
-
-
Papassotiropoulos, A.1
Wollmer, M.A.2
Aguzzi, A.3
Hock, C.4
Nitsch, R.M.5
de Quervain, D.J.6
-
105
-
-
0032509499
-
Copper stimulates endocytosis of the prion protein
-
Pauly P.C., and Harris D.A. Copper stimulates endocytosis of the prion protein. J Biol Chem 273 (1998) 33107-33110
-
(1998)
J Biol Chem
, vol.273
, pp. 33107-33110
-
-
Pauly, P.C.1
Harris, D.A.2
-
106
-
-
0035799312
-
Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region
-
Perera W.S., and Hooper N.M. Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region. Curr Biol 11 (2001) 519-523
-
(2001)
Curr Biol
, vol.11
, pp. 519-523
-
-
Perera, W.S.1
Hooper, N.M.2
-
107
-
-
0041888516
-
Trafficking of prion proteins through a caveolae-mediated endosomal pathway
-
Peters P.J., Mironov Jr. A., Peretz D., van Donselaar E., Leclerc E., Erpel S., et al. Trafficking of prion proteins through a caveolae-mediated endosomal pathway. J Cell Biol 162 (2003) 703-717
-
(2003)
J Cell Biol
, vol.162
, pp. 703-717
-
-
Peters, P.J.1
Mironov Jr., A.2
Peretz, D.3
van Donselaar, E.4
Leclerc, E.5
Erpel, S.6
-
108
-
-
1042289627
-
PrPc on the road: trafficking of the cellular prion protein
-
Prado M.A., Alves-Silva J., Magalhaes A.C., Prado V.F., Linden R., Martins V.R., et al. PrPc on the road: trafficking of the cellular prion protein. J Neurochem 88 (2004) 769-781
-
(2004)
J Neurochem
, vol.88
, pp. 769-781
-
-
Prado, M.A.1
Alves-Silva, J.2
Magalhaes, A.C.3
Prado, V.F.4
Linden, R.5
Martins, V.R.6
-
109
-
-
0033081356
-
Prion protein and species barriers in the transmissible spongiform encephalopathies
-
Priola S.A. Prion protein and species barriers in the transmissible spongiform encephalopathies. Biomed Pharmacother 53 (1999) 27-33
-
(1999)
Biomed Pharmacother
, vol.53
, pp. 27-33
-
-
Priola, S.A.1
-
110
-
-
0035803405
-
Glycosylation influences cross-species formation of protease-resistant prion protein
-
Priola S.A., and Lawson V.A. Glycosylation influences cross-species formation of protease-resistant prion protein. EMBO J 20 (2001) 6692-6699
-
(2001)
EMBO J
, vol.20
, pp. 6692-6699
-
-
Priola, S.A.1
Lawson, V.A.2
-
111
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner S.B. Novel proteinaceous infectious particles cause scrapie. Science 216 (1982) 136-144
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
112
-
-
0024634456
-
Creutzfeldt-Jakob disease and scrapie prions
-
Prusiner S.B. Creutzfeldt-Jakob disease and scrapie prions. Alzheimer Dis Assoc Disord 3 (1989) 52-78
-
(1989)
Alzheimer Dis Assoc Disord
, vol.3
, pp. 52-78
-
-
Prusiner, S.B.1
-
113
-
-
0027735089
-
Prion encephalopathies of animals and humans
-
Prusiner S.B. Prion encephalopathies of animals and humans. Dev Biol Stand 80 (1993) 31-44
-
(1993)
Dev Biol Stand
, vol.80
, pp. 31-44
-
-
Prusiner, S.B.1
-
114
-
-
0025059273
-
Prion diseases of the central nervous system
-
Prusiner S.B., and DeArmond S.J. Prion diseases of the central nervous system. Monogr Pathol (1990) 86-122
-
(1990)
Monogr Pathol
, pp. 86-122
-
-
Prusiner, S.B.1
DeArmond, S.J.2
-
115
-
-
0026181912
-
Molecular biology and pathology of scrapie and the prion diseases of humans
-
Prusiner S.B., and DeArmond S.J. Molecular biology and pathology of scrapie and the prion diseases of humans. Brain Pathol 1 (1991) 297-310
-
(1991)
Brain Pathol
, vol.1
, pp. 297-310
-
-
Prusiner, S.B.1
DeArmond, S.J.2
-
116
-
-
0019324430
-
Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent
-
Prusiner S.B., Groth D.F., Cochran S.P., Masiarz F.R., McKinley M.P., and Martinez H.M. Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent. Biochemistry 19 (1980) 4883-4891
-
(1980)
Biochemistry
, vol.19
, pp. 4883-4891
-
-
Prusiner, S.B.1
Groth, D.F.2
Cochran, S.P.3
Masiarz, F.R.4
McKinley, M.P.5
Martinez, H.M.6
-
117
-
-
0023731629
-
Novel mechanisms of degeneration of the central nervous system-prion structure and biology
-
Prusiner S.B., Stahl N., and DeArmond S.J. Novel mechanisms of degeneration of the central nervous system-prion structure and biology. Ciba Found Symp 135 (1988) 239-260
-
(1988)
Ciba Found Symp
, vol.135
, pp. 239-260
-
-
Prusiner, S.B.1
Stahl, N.2
DeArmond, S.J.3
-
118
-
-
0027491308
-
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies
-
Prusiner S.B., Groth D., Serban A., Koehler R., Foster D., Torchia M., et al. Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies. Proc Natl Acad Sci USA 90 (1993) 10608-10612
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10608-10612
-
-
Prusiner, S.B.1
Groth, D.2
Serban, A.3
Koehler, R.4
Foster, D.5
Torchia, M.6
-
119
-
-
0034018313
-
Ecosystems supporting clusters of sporadic TSEs demonstrate excesses of the radical-generating divalent cation manganese and deficiencies of antioxidant co factors Cu, Se, Fe, Zn. Does a foreign cation substitution at prion protein's Cu domain initiate TSE?
-
Purdey M. Ecosystems supporting clusters of sporadic TSEs demonstrate excesses of the radical-generating divalent cation manganese and deficiencies of antioxidant co factors Cu, Se, Fe, Zn. Does a foreign cation substitution at prion protein's Cu domain initiate TSE?. Med Hypotheses 54 (2000) 278-306
-
(2000)
Med Hypotheses
, vol.54
, pp. 278-306
-
-
Purdey, M.1
-
120
-
-
3242756751
-
Elevated silver, barium and strontium in antlers, vegetation and soils sourced from CWD cluster areas: do Ag/Ba/Sr piezoelectric crystals represent the transmissible pathogenic agent in TSEs?
-
Purdey M. Elevated silver, barium and strontium in antlers, vegetation and soils sourced from CWD cluster areas: do Ag/Ba/Sr piezoelectric crystals represent the transmissible pathogenic agent in TSEs?. Med Hypotheses 63 (2004) 211-225
-
(2004)
Med Hypotheses
, vol.63
, pp. 211-225
-
-
Purdey, M.1
-
121
-
-
0035815738
-
Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform
-
Quaglio E., Chiesa R., and Harris D.A. Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform. J Biol Chem 276 (2001) 11432-11438
-
(2001)
J Biol Chem
, vol.276
, pp. 11432-11438
-
-
Quaglio, E.1
Chiesa, R.2
Harris, D.A.3
-
122
-
-
0037715143
-
Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery
-
Rachidi W., Vilette D., Guiraud P., Arlotto M., Riondel J., Laude H., et al. Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery. J Biol Chem 278 (2003) 9064-9072
-
(2003)
J Biol Chem
, vol.278
, pp. 9064-9072
-
-
Rachidi, W.1
Vilette, D.2
Guiraud, P.3
Arlotto, M.4
Riondel, J.5
Laude, H.6
-
123
-
-
0029031422
-
Clinical and genetic studies of fatal familial insomnia
-
Reder A.T., Mednick A.S., Brown P., Spire J.P., Van Cauter E., Wollmann R.L., et al. Clinical and genetic studies of fatal familial insomnia. Neurology 45 (1995) 1068-1075
-
(1995)
Neurology
, vol.45
, pp. 1068-1075
-
-
Reder, A.T.1
Mednick, A.S.2
Brown, P.3
Spire, J.P.4
Van Cauter, E.5
Wollmann, R.L.6
-
124
-
-
0033752805
-
Non-pathogenic prion protein (PrPc) acts as a cell-surface signal transducer
-
Reilly C.E. Non-pathogenic prion protein (PrPc) acts as a cell-surface signal transducer. J Neurol 247 (2000) 819-820
-
(2000)
J Neurol
, vol.247
, pp. 819-820
-
-
Reilly, C.E.1
-
125
-
-
12144291352
-
Micellar environments induce structuring of the N-terminal tail of the prion protein
-
Renner C., Fiori S., Fiorino F., Landgraf D., Deluca D., Mentler M., et al. Micellar environments induce structuring of the N-terminal tail of the prion protein. Biopolymers 73 (2004) 421-433
-
(2004)
Biopolymers
, vol.73
, pp. 421-433
-
-
Renner, C.1
Fiori, S.2
Fiorino, F.3
Landgraf, D.4
Deluca, D.5
Mentler, M.6
-
126
-
-
0037366963
-
Transmissible spongiform encephalopathy update and implications for blood safety
-
Ricketts M.N., and Brown P. Transmissible spongiform encephalopathy update and implications for blood safety. Clin Lab Med 23 (2003) 129-137
-
(2003)
Clin Lab Med
, vol.23
, pp. 129-137
-
-
Ricketts, M.N.1
Brown, P.2
-
127
-
-
0142135128
-
Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons
-
Roucou X., Guo Q., Zhang Y., Goodyer C.G., and LeBlanc A.C. Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons. J Biol Chem 278 (2003) 40877-40881
-
(2003)
J Biol Chem
, vol.278
, pp. 40877-40881
-
-
Roucou, X.1
Guo, Q.2
Zhang, Y.3
Goodyer, C.G.4
LeBlanc, A.C.5
-
128
-
-
9144257861
-
Prion protein suppresses perturbation of cellular copper homeostasis under oxidative conditions
-
Sakudo A., Lee D.C., Yoshimura E., Nagasaka S., Nitta K., Saeki K., et al. Prion protein suppresses perturbation of cellular copper homeostasis under oxidative conditions. Biochem Biophys Res Commun 313 (2004) 850-855
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 850-855
-
-
Sakudo, A.1
Lee, D.C.2
Yoshimura, E.3
Nagasaka, S.4
Nitta, K.5
Saeki, K.6
-
129
-
-
18544376071
-
Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth
-
Santuccione A., Sytnyk V., Leshchyns'ka I., and Schachner M. Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth. J Cell Biol 169 (2005) 341-354
-
(2005)
J Cell Biol
, vol.169
, pp. 341-354
-
-
Santuccione, A.1
Sytnyk, V.2
Leshchyns'ka, I.3
Schachner, M.4
-
130
-
-
0025103308
-
Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins
-
Serban D., Taraboulos A., DeArmond S.J., and Prusiner S.B. Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins. Neurology 40 (1990) 110-117
-
(1990)
Neurology
, vol.40
, pp. 110-117
-
-
Serban, D.1
Taraboulos, A.2
DeArmond, S.J.3
Prusiner, S.B.4
-
131
-
-
19544363062
-
Prions as adaptive conduits of memory and inheritance
-
Shorter J., and Lindquist S. Prions as adaptive conduits of memory and inheritance. Nat Rev Genet 6 (2005) 435-450
-
(2005)
Nat Rev Genet
, vol.6
, pp. 435-450
-
-
Shorter, J.1
Lindquist, S.2
-
132
-
-
0348077417
-
A neuronal isoform of the aplysia CPEB has prion-like properties
-
Si K., Lindquist S., and Kandel E.R. A neuronal isoform of the aplysia CPEB has prion-like properties. Cell 115 (2003) 879-891
-
(2003)
Cell
, vol.115
, pp. 879-891
-
-
Si, K.1
Lindquist, S.2
Kandel, E.R.3
-
133
-
-
0345306739
-
Copper chelation delays the onset of prion disease
-
Sigurdsson E.M., Brown D.R., Alim M.A., Scholtzova H., Carp R., Meeker H.C., et al. Copper chelation delays the onset of prion disease. J Biol Chem 278 (2003) 46199-46202
-
(2003)
J Biol Chem
, vol.278
, pp. 46199-46202
-
-
Sigurdsson, E.M.1
Brown, D.R.2
Alim, M.A.3
Scholtzova, H.4
Carp, R.5
Meeker, H.C.6
-
134
-
-
0029854307
-
Fatal familial insomnia: a seventh family
-
Silburn P., Cervenakova L., Varghese P., Tannenberg A., Brown P., and Boyle R. Fatal familial insomnia: a seventh family. Neurology 47 (1996) 1326-1328
-
(1996)
Neurology
, vol.47
, pp. 1326-1328
-
-
Silburn, P.1
Cervenakova, L.2
Varghese, P.3
Tannenberg, A.4
Brown, P.5
Boyle, R.6
-
135
-
-
0037965529
-
Prion protein selectively binds copper (II) ions
-
Stockel J., Safar J., Wallace A.C., Cohen F.E., and Prusiner S.B. Prion protein selectively binds copper (II) ions. Biochemistry 37 (1998) 7185-7193
-
(1998)
Biochemistry
, vol.37
, pp. 7185-7193
-
-
Stockel, J.1
Safar, J.2
Wallace, A.C.3
Cohen, F.E.4
Prusiner, S.B.5
-
136
-
-
15544380905
-
The 'lipid raft' microdomain proteins reggie-1 and reggie-2 (flotillins) are scaffolds for protein interaction and signalling
-
Stuermer C.A., and Plattner H. The 'lipid raft' microdomain proteins reggie-1 and reggie-2 (flotillins) are scaffolds for protein interaction and signalling. Biochem Soc Symp (2005) 109-118
-
(2005)
Biochem Soc Symp
, pp. 109-118
-
-
Stuermer, C.A.1
Plattner, H.2
-
137
-
-
0033582935
-
Prion protein of 106 residues creates an artificial transmission barrier for prion replication in transgenic mice
-
Supattapone S., Bosque P., Muramoto T., Wille H., Aagaard C., Peretz D., et al. Prion protein of 106 residues creates an artificial transmission barrier for prion replication in transgenic mice. Cell 96 (1999) 869-878
-
(1999)
Cell
, vol.96
, pp. 869-878
-
-
Supattapone, S.1
Bosque, P.2
Muramoto, T.3
Wille, H.4
Aagaard, C.5
Peretz, D.6
-
138
-
-
0029132280
-
First experimental transmission of fatal familial insomnia
-
Tateishi J., Brown P., Kitamoto T., Hoque Z.M., Roos R., Wollman R., et al. First experimental transmission of fatal familial insomnia. Nature 376 (1995) 434-435
-
(1995)
Nature
, vol.376
, pp. 434-435
-
-
Tateishi, J.1
Brown, P.2
Kitamoto, T.3
Hoque, Z.M.4
Roos, R.5
Wollman, R.6
-
139
-
-
0028882424
-
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
-
Telling G.C., Scott M., Mastrianni J., Gabizon R., Torchia M., Cohen F.E., et al. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell 83 (1995) 79-90
-
(1995)
Cell
, vol.83
, pp. 79-90
-
-
Telling, G.C.1
Scott, M.2
Mastrianni, J.3
Gabizon, R.4
Torchia, M.5
Cohen, F.E.6
-
140
-
-
12644272790
-
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity
-
Telling G.C., Parchi P., DeArmond S.J., Cortelli P., Montagna P., Gabizon R., et al. Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science 274 (1996) 2079-2082
-
(1996)
Science
, vol.274
, pp. 2079-2082
-
-
Telling, G.C.1
Parchi, P.2
DeArmond, S.J.3
Cortelli, P.4
Montagna, P.5
Gabizon, R.6
-
141
-
-
0037083888
-
Metal imbalance and compromised antioxidant function are early changes in prion disease
-
Thackray A.M., Knight R., Haswell S.J., Bujdoso R., and Brown D.R. Metal imbalance and compromised antioxidant function are early changes in prion disease. Biochem J 362 (2002) 253-258
-
(2002)
Biochem J
, vol.362
, pp. 253-258
-
-
Thackray, A.M.1
Knight, R.2
Haswell, S.J.3
Bujdoso, R.4
Brown, D.R.5
-
142
-
-
13844299007
-
Copper binding to prion octarepeat peptides, a combined metal chelate affinity and immunochemical approaches
-
Todorova-Balvay D., Simon S., Creminon C., Grassi J., Srikrishnan T., and Vijayalakshmi M.A. Copper binding to prion octarepeat peptides, a combined metal chelate affinity and immunochemical approaches. J Chromatogr B Anal Technol Biomed Life Sci 818 (2005) 75-82
-
(2005)
J Chromatogr B Anal Technol Biomed Life Sci
, vol.818
, pp. 75-82
-
-
Todorova-Balvay, D.1
Simon, S.2
Creminon, C.3
Grassi, J.4
Srikrishnan, T.5
Vijayalakshmi, M.A.6
-
143
-
-
12744263653
-
Extracellular copper ions regulate cellular prion protein (PrPC) expression and metabolism in neuronal cells
-
Toni M., Massimino M.L., Griffoni C., Salvato B., Tomasi V., and Spisni E. Extracellular copper ions regulate cellular prion protein (PrPC) expression and metabolism in neuronal cells. FEBS Lett 579 (2005) 741-744
-
(2005)
FEBS Lett
, vol.579
, pp. 741-744
-
-
Toni, M.1
Massimino, M.L.2
Griffoni, C.3
Salvato, B.4
Tomasi, V.5
Spisni, E.6
-
144
-
-
0023676109
-
Purification and properties of the cellular and scrapie hamster prion proteins
-
Turk E., Teplow D.B., Hood L.E., and Prusiner S.B. Purification and properties of the cellular and scrapie hamster prion proteins. Eur J Biochem 176 (1988) 21-30
-
(1988)
Eur J Biochem
, vol.176
, pp. 21-30
-
-
Turk, E.1
Teplow, D.B.2
Hood, L.E.3
Prusiner, S.B.4
-
145
-
-
27444442715
-
Induction of cellular prion protein (PrPC) gene expression by copper in neurons
-
Varela-Nallar L., Toledo E.M., Larrondo L.F., Cabral A.L., Martins V.R., and Inestrosa N.C. Induction of cellular prion protein (PrPC) gene expression by copper in neurons. Am J Physiol Cell Physiol (2005)
-
(2005)
Am J Physiol Cell Physiol
-
-
Varela-Nallar, L.1
Toledo, E.M.2
Larrondo, L.F.3
Cabral, A.L.4
Martins, V.R.5
Inestrosa, N.C.6
-
146
-
-
0033515029
-
Copper binding to the prion protein: structural implications of four identical cooperative binding sites
-
Viles J.H., Cohen F.E., Prusiner S.B., Goodin D.B., Wright P.E., and Dyson H. Copper binding to the prion protein: structural implications of four identical cooperative binding sites. Proc Natl Acad Sci USA 96 (1999) 2042-2047
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2042-2047
-
-
Viles, J.H.1
Cohen, F.E.2
Prusiner, S.B.3
Goodin, D.B.4
Wright, P.E.5
Dyson, H.6
-
147
-
-
0035814903
-
Local structural plasticity of the prion protein. Analysis of NMR relaxation dynamics
-
Viles J.H., Donne D., Kroon G., Prusiner S.B., Cohen F.E., Dyson H.J., et al. Local structural plasticity of the prion protein. Analysis of NMR relaxation dynamics. Biochemistry 40 (2001) 2743-2753
-
(2001)
Biochemistry
, vol.40
, pp. 2743-2753
-
-
Viles, J.H.1
Donne, D.2
Kroon, G.3
Prusiner, S.B.4
Cohen, F.E.5
Dyson, H.J.6
-
150
-
-
0033996803
-
Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry
-
Whittal R.M., Ball H.L., Cohen F.E., Burlingame A.L., Prusiner S.B., and Baldwin M.A. Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry. Protein Sci 9 (2000) 332-343
-
(2000)
Protein Sci
, vol.9
, pp. 332-343
-
-
Whittal, R.M.1
Ball, H.L.2
Cohen, F.E.3
Burlingame, A.L.4
Prusiner, S.B.5
Baldwin, M.A.6
-
151
-
-
0026871312
-
Spongiform encephalopathies in Cervidae
-
Williams E.S., and Young S. Spongiform encephalopathies in Cervidae. Rev Sci Tech 11 (1992) 551-567
-
(1992)
Rev Sci Tech
, vol.11
, pp. 551-567
-
-
Williams, E.S.1
Young, S.2
-
152
-
-
0034726713
-
Sy MS Prion disease: a loss of antioxidant function?
-
Wong B.S., Pan T., Liu T., Li R., Petersen R.B., Jones I.M., et al. Sy MS Prion disease: a loss of antioxidant function?. Biochem Biophys Res Commun 275 (2000) 249-252
-
(2000)
Biochem Biophys Res Commun
, vol.275
, pp. 249-252
-
-
Wong, B.S.1
Pan, T.2
Liu, T.3
Li, R.4
Petersen, R.B.5
Jones, I.M.6
-
153
-
-
0034764599
-
Sy MS Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities
-
Wong B.S., Brown D.R., Pan T., Whiteman M., Liu T., Bu X., et al. Sy MS Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities. J Neurochem 79 (2001) 689-698
-
(2001)
J Neurochem
, vol.79
, pp. 689-698
-
-
Wong, B.S.1
Brown, D.R.2
Pan, T.3
Whiteman, M.4
Liu, T.5
Bu, X.6
-
154
-
-
33747191207
-
Metal trace elements and their role in the animal organism
-
Wysokinska Z. Metal trace elements and their role in the animal organism. Postepy Hig Med Dosw 18 (1964) 593-611
-
(1964)
Postepy Hig Med Dosw
, vol.18
, pp. 593-611
-
-
Wysokinska, Z.1
-
155
-
-
10444235674
-
Effect of protease treatment on plasma infectivity in variant Creutzfeldt-Jakob disease mice
-
Yakovleva O., Janiak A., McKenzie C., McShane L., Brown P., and Cervenakova L. Effect of protease treatment on plasma infectivity in variant Creutzfeldt-Jakob disease mice. Transfusion 44 (2004) 1700-1705
-
(2004)
Transfusion
, vol.44
, pp. 1700-1705
-
-
Yakovleva, O.1
Janiak, A.2
McKenzie, C.3
McShane, L.4
Brown, P.5
Cervenakova, L.6
-
156
-
-
0344099404
-
On-column purification and refolding of recombinant bovine prion protein: using its octarepeat sequences as a natural affinity tag
-
Yin S.M., Zheng Y., and Tien P. On-column purification and refolding of recombinant bovine prion protein: using its octarepeat sequences as a natural affinity tag. Protein Expres Purif 32 (2003) 104-109
-
(2003)
Protein Expres Purif
, vol.32
, pp. 104-109
-
-
Yin, S.M.1
Zheng, Y.2
Tien, P.3
-
157
-
-
18444397736
-
Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection
-
Zanata S.M., Lopes M.H., Mercadante A.F., Hajj G.N., Chiarini L.B., Nomizo R., et al. Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. EMBO J 21 (2002) 3307-3316
-
(2002)
EMBO J
, vol.21
, pp. 3307-3316
-
-
Zanata, S.M.1
Lopes, M.H.2
Mercadante, A.F.3
Hajj, G.N.4
Chiarini, L.B.5
Nomizo, R.6
-
158
-
-
0033066555
-
Infectivity of scrapie prions bound to a stainless steel surface
-
Zobeley E., Flechsig E., Cozzio A., Enari M., and Weissmann C. Infectivity of scrapie prions bound to a stainless steel surface. Mol Med 5 (1999) 240-243
-
(1999)
Mol Med
, vol.5
, pp. 240-243
-
-
Zobeley, E.1
Flechsig, E.2
Cozzio, A.3
Enari, M.4
Weissmann, C.5
|