Copper binding to PrPC may inhibit prion disease propagation

Brain Research

Volumn 993, Issue 1-2, 2003, Pages 192-200

  Hijazi, Nuha ^a   Shaked, Yuval ^a   Rosenmann, Hana ^a   Ben Hur, Tamir ^a   Gabizon, Ruth ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Copper binding; Prion disease propagation; PrPC

Indexed keywords

COPPER SULFATE; DRINKING WATER; PRION PROTEIN; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LEVEL; CEREBELLUM CORTEX; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE ACTIVITY; HAMSTER; IMMUNOHISTOCHEMISTRY; MALE; NEUROBLASTOMA CELL; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONTENT; SCRAPIE; ANIMAL; ATOMIC ABSORPTION SPECTROMETRY; BIOSYNTHESIS; BRAIN; CELL LINE; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; DOSE RESPONSE; DRUG EFFECT; GENETICS; HUMAN; IMMUNOBLOTTING; INFECTION; METABOLISM; METHODOLOGY; PATHOLOGY; PROTEIN TRANSPORT; PURKINJE CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME;

ANIMALS; BRAIN; CELL LINE; COPPER SULFATE; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFECTION; MALE; MICROSCOPY, CONFOCAL; PRION DISEASES; PROTEIN BINDING; PROTEIN TRANSPORT; PRPC PROTEINS; PRPSC PROTEINS; PURKINJE CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECTROPHOTOMETRY, ATOMIC; TIME FACTORS;

EID: 0345714734     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2003.09.014     Document Type: Article

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