Copper binding to the prion protein: Structural implications of four identical cooperative binding sites

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 5, 1999, Pages 2042-2047

  Viles, John H ^a   Cohen, Fred E ^b,c   Prusiner, Stanley B ^b   Goodin, David B ^a   Wright, Peter E ^a   Dyson, H Jane ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Circular dichroism; Electron spin resonance; Nuclear magnetic resonance; Octarepeat peptides

Indexed keywords

COPPER; HISTIDINE; IMIDAZOLE; NITROGEN; OCTAPEPTIDE; OXYGEN; PRION PROTEIN; WATER;

ABSORPTION SPECTROSCOPY; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CIRCULAR DICHROISM; COMPLEX FORMATION; COPPER METABOLISM; ELECTRON SPIN RESONANCE; METAL BINDING; PH; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

AMINO ACID SEQUENCE; BINDING SITES; CIRCULAR DICHROISM; COPPER; ELECTRON SPIN RESONANCE SPECTROSCOPY; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PRIONS; PROTEIN CONFORMATION; REPETITIVE SEQUENCES, AMINO ACID;

EID: 0033515029     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.5.2042     Document Type: Article

References (34)

1. Prusiner, S. B. (1997) Science 278, 245-251.
2. Chazot, G., Broussolle, E., Lapras, C., Blattler, T., Aguzzi, A. & Kopp, N. (1996) Lancet 347, 1181.
3. Will, R. G., Ironside, J. W., Zeidler, M., Cousens, S. N., Estibeiro, K., Alperovitch, A., Poser, S., Pocchiari, M., Hofman, A. & Smith, P. G. (1996) Lancet 347, 921-925.
4. Prusiner, S. B. (1982) Science 216, 136-144.
5. Pan, K.-M., Baldwin, M., Nguyen, J., Gasset, M., Serban, A., Groth, D., Mehlhorn, I., Huang, Z., Fletterick, R. J., Cohen, F. E., et al. (1993) Proc. Natl. Acad. Sci. USA 90, 10962-10966.
6. Horwich, A. L. & Weissman, J. S. (1997) Cell 89, 499-510.
7. Kaneko, K., Zulianello, L., Scott, M., Cooper, C. M., Wallace, A. C., James, T. L., Cohen, F. E. & Prusiner, S. B. (1997) Proc. Natl. Acad. Sci. USA 94, 10069-10074.
8. Brown, D. R., Qin, K. F., Herms, J. W., Madlung, A., Manson, J., Strome, R., Fraser, P. E., Kruck, T., Von Bohlen, A., Schulz-Schaeffer, W., et al. (1997) Nature (London) 390, 684-687.
9. Brown, D. R., Schmidt, B. & Kretzschmar, H. A. (1998) J. Neurochem. 70, 1686-1693.
10. Riek, R., Hornemann, S., Wider, G., Billeter, M., Glockshuber, R. & Wüthrich, K. (1996) Nature (London) 382, 180-182.
11. Billeter, M., Riek, R., Wider, G., Hornemann, S., Glockshuber, R. & Wüthrich, K. (1997) Proc. Natl. Acad. Sci. USA 94, 7281-7285.
12. James, T. L., Liu, H., Ulyanov, N. B., Farr-Jones, S., Zhang, H., Donne, D. G., Kaneko, K., Groth, D., Mehlhorn, I., Prusiner, S. B., et al. (1997) Proc. Natl. Acad. Sci. USA 94, 10086-10091.
13. Donne, D. G., Viles, J. H., Groth, D., Mehlhorn, I., James, T. L., Cohen, F. E., Prusiner, S. B., Wright, P. E. & Dyson, H. J. (1997) Proc. Natl. Acad. Sci. USA 94, 13452-13457.
14. Harris, D. A., Falls, D. L., Johnson, F. A. & Fischbach, G. D. (1991) Proc. Natl. Acad. Sci. USA 88, 7664-7668.
15. Poulter, M., Baker, H. F., Frith, C. D., Leach, M., Lofthouse, R., Ridley, R. M., Shah, T., Owen. F., Collinge, J., Brown, J., et al. (1998) Brain 115, 675-685.
16. Sulkowski, E. (1992) FEBS Lett. 307, 129-130.
17. Pan, K. M., Stahl, N. & Prusiner, S. B. (1992) Protein Sci. 1, 1343-1352.
18. Hornshaw, M. P., McDermott, J. R., Candy, J. M. & Lakey, J. H. (1995) Biochem. Biophys. Res. Commun. 214, 993-999.
19. Stöckel, J., Safar, J., Wallace, A. C., Cohen, F. E. & Prusiner, S. B. (1998) Biochemistry 37, 7185-7193.
20. Mehlhorn, I., Groth, D., Stockel, J., Moffat, B., Reilly, D., Yansura, D., Willett, W. S., Baldwin, M., Fletterick, R., Cohen, F. E., et al. (1996) Biochemistry 35, 5528-5537.
21. Gill, S. C. & von Hippel, P. H. (1989) Anal. Biochem. 182, 319-326.
22. Piotto, M., Saudek, V. & Sklenár, V. (1992) J. Biomol. NMR 2, 661-665.
23. Shaka, A. J., Lee, C. J. & Pines, A. (1988) J. Magn. Reson. 77, 274-293.
24. Miura, T., Hori-i, A. & Takeuchi, H. (1996) FEBS Lett. 396, 248-252.
25. Peisach, J. & Blumberg, W. E. (1974) Arch. Biochem. Biophys. 165, 691-708.
26. Perkins, C. M., Roes, N. J., Weinstein, B., Stenkamp, R. E., Jensen, L. H. & Pickart, L. (1984) Inorg. Chim. Acta 82, 93-99.
27. Freedman, J. H., Pickart, L., Weinstein, B., Mims, W. B. & Peisach, J. (1982) Biochemistry 21, 4540-4544.
28. Solomon, E. I., Lowery, M. D., LaCroix, L. B. & Root, D. E. (1993) Methods Enzymol. 226, 1-33.
29. Bryce, G. F. & Gurd, F. R. (1966) J. Biol. Chem. 241, 122-129.
30. Bryce, G. F., Roeske, R. W. & Gurd, F. R. (1965) J. Biol. Chem. 240, 3837-3846.
31. Freeman, H. C. (1967) Adv. Protein Chem. 22, 257-424.
32. Camerman, N., Camerman, A. & Sarkar, B. (1976) Can. J. Chem. 54, 1309-1316.
33. Parge, H. E., Hallewell, R. A. & Tainer, J. A. (1992) Proc. Natl. Acad. Sci. USA 89, 6109-6113.
34. Sundberg, R. J. & Martin, R. B. (1974) Chem. Rev. 74, 471-517.