Copper Chelation Delays the Onset of Prion Disease

Journal of Biological Chemistry

Volumn 278, Issue 47, 2003, Pages 46199-46202

  Sigurdsson, Einar M ^a,d   Brown, David R ^b   Alim, Muhammad A ^a   Scholtzova, Henrieta ^a   Carp, Richard ^c   Meeker, Harry C ^c   Prelli, Frances ^a   Frangione, Blas ^a   Wisniewski, Thomas ^a,d  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Bath   (United Kingdom)

^c NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^d Millhauser Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; CORRELATION METHODS; DISEASE CONTROL; DISEASES; ENZYME KINETICS;

INCUBATION PERIOD;

PROTEINS;

CHELATING AGENT; COPPER; PENICILLAMINE; PRION PROTEIN; PROTEINASE K;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHELATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COPPER BLOOD LEVEL; CORRELATION ANALYSIS; DISEASE COURSE; DRUG EFFECT; IN VITRO STUDY; INOCULATION; MOUSE; NONHUMAN; ONSET AGE; PRION DISEASE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ANIMALS; BRAIN CHEMISTRY; CHELATING AGENTS; CHELATION THERAPY; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASE K; MICE; MICE, INBRED STRAINS; PENICILLAMINE; PRION DISEASES; PRPSC PROTEINS; TIME FACTORS;

ANIMALIA;

EID: 0345306739     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300303200     Document Type: Article

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