Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: Implications for species barrier in prion uptake from the intestine

Journal of Neuroscience

Volumn 24, Issue 50, 2004, Pages 11280-11290

  Mishra, Ravi Shankar ^a   Basu, Subhabrata ^a   Gu, Yaping ^a   Luo, Xiu ^a   Zou, Wen Quan ^a   Mishra, Richa ^a   Li, Ruliang ^a   Chen, Shu G ^a   Gambetti, Pierluigi ^a   Fujioka, Hisashi ^a   Singh, Neena ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Caco 2; Epithelial cell barrier; Ferritin; New variant CJD; Prion infection; PrP transport; Subclinical infection

Indexed keywords

FERRITIN; PRION PROTEIN; PROTEINASE;

AGED; ARTICLE; CARBOXY TERMINAL SEQUENCE; CASE REPORT; CREUTZFELDT JAKOB DISEASE; DISEASE TRANSMISSION; EPITHELIUM CELL; HUMAN; INTESTINE; LOW TEMPERATURE; MALE; PATHOGENESIS; PRION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AGED; BRAIN; CACO-2 CELLS; CREUTZFELDT-JAKOB SYNDROME; FEMALE; FERRITINS; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MALE; MIDDLE AGED; MULTIPROTEIN COMPLEXES; PEPSIN A; PEPTIDE FRAGMENTS; PEPTIDE HYDROLASES; PROTEIN BINDING; PROTEIN TRANSPORT; PRPC PROTEINS; PRPSC PROTEINS; SPECIES SPECIFICITY; TIGHT JUNCTIONS;

EID: 10644241804     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2864-04.2004     Document Type: Article

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