Interaction of the human prion PrP(106-126) sequence with copper(II), manganese(II), and zinc(II): NMR and EPR studies

Journal of the American Chemical Society

Volumn 127, Issue 3, 2005, Pages 996-1006

  Gaggelli, Elena ^a   Bernardi, Francesca ^a   Molteni, Elena ^a   Pogni, Rebecca ^a   Valensin, Daniela ^a   Valensin, Gianni ^a   Remelli, Maurizio ^b   Luczkowski, Marek ^c   Kozlowski, Henryk ^c  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF WROC AW   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; HYDROGEN BONDS; HYDROPHOBICITY; MANGANESE; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARAMAGNETISM; ZINC;

COPPER-BINDING PROPERTIES; HUMAN PRION PROTEINS; METAL COMPLEXES;

PROTEINS;

AMIDE; CARBONYL DERIVATIVE; CARBOXYL GROUP; COORDINATION COMPOUND; COPPER; GLYCINE; HISTIDINE; IMIDAZOLE; LEUCINE; MANGANESE; METAL COMPLEX; METAL ION; NITROGEN; OXYGEN; PRION PROTEIN; PROTON; SYNTHETIC PEPTIDE; WATER; ZINC;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; ELECTRON SPIN RESONANCE; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; IONIZATION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR STABILITY; NUCLEAR MAGNETIC RESONANCE; PH; PROTON NUCLEAR MAGNETIC RESONANCE;

AMINO ACID SEQUENCE; CATIONS, DIVALENT; COPPER; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; HYDROPHOBICITY; MANGANESE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PRIONS; THERMODYNAMICS; ZINC;

EID: 12444341883     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja045958z     Document Type: Article

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