Copper reduction by the octapeptide repeat region of prion protein: pH dependence and implications in cellular copper uptake

Biochemistry

Volumn 44, Issue 24, 2005, Pages 8712-8720

  Miura, Takashi ^a   Sasaki, Satoshi ^a   Toyama, Akira ^a   Takeuchi, Hideo ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; COPPER; IONS; PH EFFECTS; PHYSIOLOGY; RAMAN SPECTROSCOPY; REACTION KINETICS; REDUCTION; SUBSTRATES;

KINETIC PROPERTIES; MOLECULAR MECHANICS; PATHOGENESIS; PRION PROTEIN (PRP);

PROTEINS;

COORDINATION COMPOUND; COPPER; GLYCOLIPID; HISTIDINE; MEMBRANE PROTEIN; NITROGEN; OCTAPEPTIDE; PRION PROTEIN; TRYPTOPHAN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; BRAIN SPONGIOSIS; CELL SURFACE; CELL TRANSPORT; CHEMICAL REACTION KINETICS; ENDOSOME; EXTRACELLULAR SPACE; METAL BINDING; MOLECULAR MECHANICS; OXIDATION REDUCTION REACTION; PATHOGENESIS; PH; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TRANSPORT; RAMAN SPECTROMETRY; REDUCTION; STOICHIOMETRY; STRUCTURE ANALYSIS; TANDEM REPEAT;

AMINO ACID SEQUENCE; BINDING SITES; BIOLOGICAL TRANSPORT; COPPER; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PRIONS; PROTEIN CONFORMATION; REPETITIVE SEQUENCES, AMINO ACID; SPECTRUM ANALYSIS, RAMAN;

EID: 20544450600     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0501784     Document Type: Article

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