Cellular prion protein acquires resistance to proteolytic degradation following copper ion binding

Biological Chemistry

Volumn 385, Issue 8, 2004, Pages 739-747

  Kuczius, Thorsten ^a   Buschmann, Anne ^b   Zhang, Wenlan ^a   Karch, Helge ^a   Becker, Karsten ^a   Peters, Georg ^a   Groschup, Martin H ^b  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

BSE; Prion protein; Proteinase K; Proteolysis; Scrapie

Indexed keywords

COPPER ION; DIVALENT CATION; ISOPROTEIN; METHANOL; PRION PROTEIN; PROTEINASE K;

ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; METAL BINDING; MOUSE; NONHUMAN; PRECIPITATION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN IMMOBILIZATION; PROTEIN STABILITY;

ANIMALS; BLOTTING, WESTERN; CALCIUM; CATIONS; CATTLE; COLORIMETRY; COPPER; EDETIC ACID; ENDOPEPTIDASE K; ENZYME-LINKED IMMUNOSORBENT ASSAY; PRIONS; PROTEIN BINDING; SHEEP;

EID: 4544335297     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2004.090     Document Type: Article

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