Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities

Journal of Neurochemistry

Volumn 79, Issue 3, 2001, Pages 689-698

  Wong, Boon Seng ^a   Brown, David R ^b   Pan, Tao ^a   Whiteman, Matthew ^c   Liu, Tong ^a   Bu, Xiaodong ^d   Li, Ruliang ^a   Gambetti, Pierluigi ^a   Olesik, John ^d   Rubenstein, Richard ^e   Sy, Man Sun ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d OHIO STATE UNIVERSITY   (United States)

^e NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Copper; Lipid peroxidation; Oxidative stress; Prion; Protein oxidation; Scrapie

Indexed keywords

COPPER; GLUTATHIONE PEROXIDASE; NITRIC OXIDE; PRION PROTEIN; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; ENZYME ACTIVITY; LIPID PEROXIDATION; METAL BINDING; MOUSE; NERVE DEGENERATION; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIOXIDANTS; BRAIN; CALCIUM; COPPER; GLUTATHIONE PEROXIDASE; IRON; LIPID PEROXIDATION; MAGNESIUM; METALS; MICE; MICE, INBRED STRAINS; NITRITES; OXIDATIVE STRESS; PRIONS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PRPSC PROTEINS; SCRAPIE; SUPEROXIDE DISMUTASE; ZINC;

EID: 0034764599     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00625.x     Document Type: Article

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