-
1
-
-
0030848569
-
Incidence of Crohn's disease in Stockholm County 1955-1989
-
Lapidus A., Bernell O., Hellers G., Persson P., and Lofberg R. Incidence of Crohn's disease in Stockholm County 1955-1989. Gut 41 (1997) 480-486
-
(1997)
Gut
, vol.41
, pp. 480-486
-
-
Lapidus, A.1
Bernell, O.2
Hellers, G.3
Persson, P.4
Lofberg, R.5
-
2
-
-
0023713859
-
Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking
-
Tysk C., Lindberg E., Jarnerot G., and Floderus-Myrhed B. Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking. Gut 29 (1988) 990-996
-
(1988)
Gut
, vol.29
, pp. 990-996
-
-
Tysk, C.1
Lindberg, E.2
Jarnerot, G.3
Floderus-Myrhed, B.4
-
3
-
-
0033773642
-
Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study
-
Orholm M., Binder V., Sorensen T., Rasmussen L., and Kyvik K. Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study. Scand J Gastroenterol 35 (2000) 1075-1081
-
(2000)
Scand J Gastroenterol
, vol.35
, pp. 1075-1081
-
-
Orholm, M.1
Binder, V.2
Sorensen, T.3
Rasmussen, L.4
Kyvik, K.5
-
4
-
-
0030042271
-
Genetics versus environment in inflammatory bowel disease: results of a British twin study
-
Thompson N., Driscoll R., Pounder R., and Wakefield A. Genetics versus environment in inflammatory bowel disease: results of a British twin study. BMJ 312 (1996) 95-96
-
(1996)
BMJ
, vol.312
, pp. 95-96
-
-
Thompson, N.1
Driscoll, R.2
Pounder, R.3
Wakefield, A.4
-
6
-
-
0034991524
-
Review article: the genetics of inflammatory bowel disease
-
Ahmad T., Satsangi J., McGovern D., Bunce M., and Jewell D. Review article: the genetics of inflammatory bowel disease. Aliment Pharmacol Ther 15 (2001) 731-748
-
(2001)
Aliment Pharmacol Ther
, vol.15
, pp. 731-748
-
-
Ahmad, T.1
Satsangi, J.2
McGovern, D.3
Bunce, M.4
Jewell, D.5
-
7
-
-
0038620498
-
Inflammatory bowel disease in a Swedish twin cohort: a long-term follow-up of concordance and clinical characteristics
-
Halfvarson J., Bodin L., Tysk C., Lindberg E., and Jarnerot G. Inflammatory bowel disease in a Swedish twin cohort: a long-term follow-up of concordance and clinical characteristics. Gastroenterology 124 (2003) 1767-1773
-
(2003)
Gastroenterology
, vol.124
, pp. 1767-1773
-
-
Halfvarson, J.1
Bodin, L.2
Tysk, C.3
Lindberg, E.4
Jarnerot, G.5
-
8
-
-
0026029260
-
Prevalence of inflammatory bowel disease among relatives of patients with Crohn's disease
-
Monsen U., Bernell O., Johansson C., and Hellers G. Prevalence of inflammatory bowel disease among relatives of patients with Crohn's disease. Scand J Gastroenterol 26 (1991) 302-306
-
(1991)
Scand J Gastroenterol
, vol.26
, pp. 302-306
-
-
Monsen, U.1
Bernell, O.2
Johansson, C.3
Hellers, G.4
-
9
-
-
0027379179
-
Prevalence and family risk of ulcerative colitis and Crohn's disease: an epidemiological study among Europeans and south Asians in Leicestershire
-
Probert C., Jayanthi V., Hughes A., Thompson J., Wicks A., and Mayberry J. Prevalence and family risk of ulcerative colitis and Crohn's disease: an epidemiological study among Europeans and south Asians in Leicestershire. Gut 34 (1993) 1547-1551
-
(1993)
Gut
, vol.34
, pp. 1547-1551
-
-
Probert, C.1
Jayanthi, V.2
Hughes, A.3
Thompson, J.4
Wicks, A.5
Mayberry, J.6
-
10
-
-
0025966488
-
Familial occurrence of inflammatory bowel disease
-
Orholm M., Munkholm P., Langholz E., Nielsen O., Sorensen I., and Binder V. Familial occurrence of inflammatory bowel disease. N Engl J Med 324 (1991) 84-88
-
(1991)
N Engl J Med
, vol.324
, pp. 84-88
-
-
Orholm, M.1
Munkholm, P.2
Langholz, E.3
Nielsen, O.4
Sorensen, I.5
Binder, V.6
-
11
-
-
0029788997
-
Familial aggregation in Crohn's disease: increased age-adjusted risk and concordance in clinical characteristics
-
Peeters M., Nevens H., Baert F., et al. Familial aggregation in Crohn's disease: increased age-adjusted risk and concordance in clinical characteristics. Gastroenterology 111 (1996) 597-603
-
(1996)
Gastroenterology
, vol.111
, pp. 597-603
-
-
Peeters, M.1
Nevens, H.2
Baert, F.3
-
12
-
-
0027404560
-
Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews
-
Yang H., McElree C., Roth M., Shanahan F., Targan S., and Rotter J. Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews. Gut 34 (1993) 517-524
-
(1993)
Gut
, vol.34
, pp. 517-524
-
-
Yang, H.1
McElree, C.2
Roth, M.3
Shanahan, F.4
Targan, S.5
Rotter, J.6
-
13
-
-
0036083997
-
Familial Crohn's disease in single or multiple first-degree relatives
-
Freeman H. Familial Crohn's disease in single or multiple first-degree relatives. J Clin Gastroenterol 35 (2002) 9-13
-
(2002)
J Clin Gastroenterol
, vol.35
, pp. 9-13
-
-
Freeman, H.1
-
14
-
-
0029970133
-
Clinical patterns of familial inflammatory bowel disease
-
Satsangi J., Grootscholten C., Holt H., and Jewell D. Clinical patterns of familial inflammatory bowel disease. Gut 38 (1996) 738-741
-
(1996)
Gut
, vol.38
, pp. 738-741
-
-
Satsangi, J.1
Grootscholten, C.2
Holt, H.3
Jewell, D.4
-
15
-
-
0029810041
-
Crohn's disease: influence of age at diagnosis on site and clinical type of disease
-
Polito J., Childs B., Mellits E., Tokayer A., Harris M., and Bayless T. Crohn's disease: influence of age at diagnosis on site and clinical type of disease. Gastroenterology 111 (1996) 580-586
-
(1996)
Gastroenterology
, vol.111
, pp. 580-586
-
-
Polito, J.1
Childs, B.2
Mellits, E.3
Tokayer, A.4
Harris, M.5
Bayless, T.6
-
16
-
-
0019304236
-
Studies of family history among patients with inflammatory bowel disease
-
Farmer R., Michener W., and Mortimer E. Studies of family history among patients with inflammatory bowel disease. Clin Gastroenterology 9 (1980) 271-277
-
(1980)
Clin Gastroenterology
, vol.9
, pp. 271-277
-
-
Farmer, R.1
Michener, W.2
Mortimer, E.3
-
17
-
-
0029757462
-
Inflammatory bowel disease and the X chromosome
-
Hayward P., Satsangi J., and Jewell D. Inflammatory bowel disease and the X chromosome. Q J Med 89 (1996) 713-718
-
(1996)
Q J Med
, vol.89
, pp. 713-718
-
-
Hayward, P.1
Satsangi, J.2
Jewell, D.3
-
18
-
-
19244382144
-
Genetic defects and clinical characteristics of patients with a form of oculocutaneous albinism (Hermansky-Pudlak syndrome)
-
Gahl W., Brantly M., Kaiser-Kupfer M., et al. Genetic defects and clinical characteristics of patients with a form of oculocutaneous albinism (Hermansky-Pudlak syndrome). N Engl J Med 338 (1998) 1258-1264
-
(1998)
N Engl J Med
, vol.338
, pp. 1258-1264
-
-
Gahl, W.1
Brantly, M.2
Kaiser-Kupfer, M.3
-
19
-
-
0031667996
-
The Human Genome Project: from mapping to sequencing
-
Weissenbach J. The Human Genome Project: from mapping to sequencing. Clin Chem Lab Med 36 (1998) 511-514
-
(1998)
Clin Chem Lab Med
, vol.36
, pp. 511-514
-
-
Weissenbach, J.1
-
21
-
-
2442429216
-
Clinical relevance of advances in genetics and pharmacogenetics of IBD
-
Ahmad T., Tamboli C., Jewell D., and Colombel J. Clinical relevance of advances in genetics and pharmacogenetics of IBD. Gastroenterology 126 (2004) 1533-1549
-
(2004)
Gastroenterology
, vol.126
, pp. 1533-1549
-
-
Ahmad, T.1
Tamboli, C.2
Jewell, D.3
Colombel, J.4
-
22
-
-
0035004413
-
International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled data set: Crohn disease and chromosome 16
-
Cavanaugh J. International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled data set: Crohn disease and chromosome 16. Am J Hum Genet 68 (2001) 1165-1171
-
(2001)
Am J Hum Genet
, vol.68
, pp. 1165-1171
-
-
Cavanaugh, J.1
-
23
-
-
0033659830
-
The IBD2 locus shows linkage heterogeneity between ulcerative colitis and Crohn disease
-
Parkes M., Barmada M., Satsangi J., Weeks D., Jewell D., and Duerr R. The IBD2 locus shows linkage heterogeneity between ulcerative colitis and Crohn disease. Am J Hum Genet 67 (2000) 1605-1610
-
(2000)
Am J Hum Genet
, vol.67
, pp. 1605-1610
-
-
Parkes, M.1
Barmada, M.2
Satsangi, J.3
Weeks, D.4
Jewell, D.5
Duerr, R.6
-
24
-
-
0033358520
-
Linkage of inflammatory bowel disease to human chromosome 6p
-
Hampe J., Shaw S., Saiz R., et al. Linkage of inflammatory bowel disease to human chromosome 6p. Am J Hum Genet 65 (1999) 1647-1655
-
(1999)
Am J Hum Genet
, vol.65
, pp. 1647-1655
-
-
Hampe, J.1
Shaw, S.2
Saiz, R.3
-
25
-
-
0030007093
-
Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease
-
Satsangi J., Welsh K., Bunce M., et al. Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease. Lancet 347 (1996) 1212-1217
-
(1996)
Lancet
, vol.347
, pp. 1212-1217
-
-
Satsangi, J.1
Welsh, K.2
Bunce, M.3
-
26
-
-
11144354272
-
Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs
-
Van Heel D., Fisher S., Kirby A., Daly M., Rioux J., and Lewis C. Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs. Hum Mol Genet 13 (2004) 763-770
-
(2004)
Hum Mol Genet
, vol.13
, pp. 763-770
-
-
Van Heel, D.1
Fisher, S.2
Kirby, A.3
Daly, M.4
Rioux, J.5
Lewis, C.6
-
27
-
-
13344259990
-
Mapping of a susceptibility locus for Crohn's disease on chromosome 16
-
Hugot J., Laurent-Puig P., Gower-Rousseau C., et al. Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 379 (1996) 821-823
-
(1996)
Nature
, vol.379
, pp. 821-823
-
-
Hugot, J.1
Laurent-Puig, P.2
Gower-Rousseau, C.3
-
28
-
-
0035897904
-
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
-
Hampe J., Cuthbert A., Croucher P., et al. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 357 (2001) 1925-1928
-
(2001)
Lancet
, vol.357
, pp. 1925-1928
-
-
Hampe, J.1
Cuthbert, A.2
Croucher, P.3
-
29
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot J., Chamaillard M., Zouali H., et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411 (2001) 599-603
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.1
Chamaillard, M.2
Zouali, H.3
-
30
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y., Bonen D., Inohara N., et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411 (2001) 603-606
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.2
Inohara, N.3
-
31
-
-
0035895992
-
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
-
Ogura Y., Inohara N., Benito A., Chen F., Yamaoka S., and Nunez G. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J Biol Chem 276 (2001) 4812-4818
-
(2001)
J Biol Chem
, vol.276
, pp. 4812-4818
-
-
Ogura, Y.1
Inohara, N.2
Benito, A.3
Chen, F.4
Yamaoka, S.5
Nunez, G.6
-
32
-
-
0036373539
-
Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease
-
Yamazaki K., Takazoe M., Tanaka T., Kazumori T., and Nakamura Y. Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease. J Hum Genet 47 (2002) 469-472
-
(2002)
J Hum Genet
, vol.47
, pp. 469-472
-
-
Yamazaki, K.1
Takazoe, M.2
Tanaka, T.3
Kazumori, T.4
Nakamura, Y.5
-
33
-
-
0036306951
-
Lack of common NOD2 variants in Japanese patients with Crohn's disease
-
Inoue N., Tamura K., Kinouchi Y., et al. Lack of common NOD2 variants in Japanese patients with Crohn's disease. Gastroenterology 123 (2002) 86-91
-
(2002)
Gastroenterology
, vol.123
, pp. 86-91
-
-
Inoue, N.1
Tamura, K.2
Kinouchi, Y.3
-
34
-
-
0037265610
-
Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations
-
Croucher P., Mascheretti S., Hampe J., et al. Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations. Eur J Hum Genet 11 (2003) 6-16
-
(2003)
Eur J Hum Genet
, vol.11
, pp. 6-16
-
-
Croucher, P.1
Mascheretti, S.2
Hampe, J.3
-
35
-
-
0038235697
-
NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population
-
Leong R. NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population. Aliment Pharmacol Ther 17 (2003) 1465-1470
-
(2003)
Aliment Pharmacol Ther
, vol.17
, pp. 1465-1470
-
-
Leong, R.1
-
36
-
-
27644591952
-
Genotype-phenotype analysis in childhood-onset Crohn's disease: NOD2/CARD15 variants consistently predict phenotypic characteristics of severe disease
-
Russell R., Drummond H., Nimmo E., et al. Genotype-phenotype analysis in childhood-onset Crohn's disease: NOD2/CARD15 variants consistently predict phenotypic characteristics of severe disease. Inflamm Bowel Dis 11 (2005) 955-964
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 955-964
-
-
Russell, R.1
Drummond, H.2
Nimmo, E.3
-
37
-
-
0037379286
-
CARD15/NOD2 gene variants are associated with familially occurring and complicated forms of Crohn's disease
-
Helio T., Halme L., Lappalainen M., et al. CARD15/NOD2 gene variants are associated with familially occurring and complicated forms of Crohn's disease. Gut 52 (2003) 558-562
-
(2003)
Gut
, vol.52
, pp. 558-562
-
-
Helio, T.1
Halme, L.2
Lappalainen, M.3
-
38
-
-
0242500981
-
Association of NOD2 with Crohn's disease in a homogenous Irish population
-
Bairead E., Harmon D., Curtis A., et al. Association of NOD2 with Crohn's disease in a homogenous Irish population. Eur J Hum Gen 11 (2003) 237-244
-
(2003)
Eur J Hum Gen
, vol.11
, pp. 237-244
-
-
Bairead, E.1
Harmon, D.2
Curtis, A.3
-
39
-
-
4344671141
-
NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe?
-
Arnott I., Nimmo E., Drummond H., et al. NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe?. Genes Immun 5 (2004) 417-425
-
(2004)
Genes Immun
, vol.5
, pp. 417-425
-
-
Arnott, I.1
Nimmo, E.2
Drummond, H.3
-
40
-
-
0038724272
-
Subclinical intestinal inflammation: an inherited abnormality in Crohn's disease relatives?
-
Thjodleifsson B., Sigthorsson G., Cariglia N., et al. Subclinical intestinal inflammation: an inherited abnormality in Crohn's disease relatives?. Gastroenterology 124 (2003) 1728-1737
-
(2003)
Gastroenterology
, vol.124
, pp. 1728-1737
-
-
Thjodleifsson, B.1
Sigthorsson, G.2
Cariglia, N.3
-
41
-
-
16844365534
-
CARD15 mutations are rare in Swedish pediatric Crohn's disease
-
Idestrom M., Rubio C., Granath F., Finkel Y., and Hugot J. CARD15 mutations are rare in Swedish pediatric Crohn's disease. J Pediatr Gastroenterol Nutr 40 (2005) 456-460
-
(2005)
J Pediatr Gastroenterol Nutr
, vol.40
, pp. 456-460
-
-
Idestrom, M.1
Rubio, C.2
Granath, F.3
Finkel, Y.4
Hugot, J.5
-
42
-
-
0036202885
-
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease
-
Cuthbert A., Fisher S., Mirza M., et al. The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease. Gastroenterology 122 (2002) 867-874
-
(2002)
Gastroenterology
, vol.122
, pp. 867-874
-
-
Cuthbert, A.1
Fisher, S.2
Mirza, M.3
-
43
-
-
0036201577
-
CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
-
Lesage S., Zouali H., Cezard J., et al. CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet 70 (2002) 845-857
-
(2002)
Am J Hum Genet
, vol.70
, pp. 845-857
-
-
Lesage, S.1
Zouali, H.2
Cezard, J.3
-
44
-
-
0036202336
-
The molecular classification of the clinical manifestations of Crohn's disease
-
Ahmad T., Armuzzi A., Bunce M., et al. The molecular classification of the clinical manifestations of Crohn's disease. Gastroenterology 122 (2002) 854-866
-
(2002)
Gastroenterology
, vol.122
, pp. 854-866
-
-
Ahmad, T.1
Armuzzi, A.2
Bunce, M.3
-
45
-
-
2542574746
-
Mutations in the NOD2/CARD15 gene in Crohn's disease are associated with ileocaecal resection and are a risk factor for reoperation
-
Buning C., Genschel J., Buhner S., et al. Mutations in the NOD2/CARD15 gene in Crohn's disease are associated with ileocaecal resection and are a risk factor for reoperation. Aliment Pharmacol Ther 19 (2004) 1073-1078
-
(2004)
Aliment Pharmacol Ther
, vol.19
, pp. 1073-1078
-
-
Buning, C.1
Genschel, J.2
Buhner, S.3
-
46
-
-
12344300288
-
NOD2/CARD15 gene polymorphism in patients with inflammatory bowel disease: is Hungary different?
-
Buning C., Molnar T., Nagy F., et al. NOD2/CARD15 gene polymorphism in patients with inflammatory bowel disease: is Hungary different?. World J Gastroenterol 11 (2005) 407-411
-
(2005)
World J Gastroenterol
, vol.11
, pp. 407-411
-
-
Buning, C.1
Molnar, T.2
Nagy, F.3
-
47
-
-
13744264167
-
Variants of CARD15 are associated with an aggressive clinical course of Crohn's disease-an IG-IBD study
-
Annese V., Lombardi G., Perri F., et al. Variants of CARD15 are associated with an aggressive clinical course of Crohn's disease-an IG-IBD study. Am J Gastroenterol 100 (2005) 84-92
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 84-92
-
-
Annese, V.1
Lombardi, G.2
Perri, F.3
-
48
-
-
0037343871
-
CARD15 and Crohn's disease: healthy homozygous carriers of the 3020insC frameshift mutation
-
Linde K., Boor P., Houwing-Duistermaat J., Kuipers E., Wilson J., and de Rooij F. CARD15 and Crohn's disease: healthy homozygous carriers of the 3020insC frameshift mutation. Am J Gastroenterol 98 (2003) 613-617
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 613-617
-
-
Linde, K.1
Boor, P.2
Houwing-Duistermaat, J.3
Kuipers, E.4
Wilson, J.5
de Rooij, F.6
-
49
-
-
9144223009
-
Prevalence of mutations of the NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn disease
-
Mendoza J., Murillo L., Fernandez L., et al. Prevalence of mutations of the NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn disease. Scand J Gastroenterol 38 (2003) 1235-1240
-
(2003)
Scand J Gastroenterol
, vol.38
, pp. 1235-1240
-
-
Mendoza, J.1
Murillo, L.2
Fernandez, L.3
-
50
-
-
0037221395
-
Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan
-
Bonen D., Ogura Y., Nicolae D., et al. Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan. Gastroenterology 124 (2003) 140-146
-
(2003)
Gastroenterology
, vol.124
, pp. 140-146
-
-
Bonen, D.1
Ogura, Y.2
Nicolae, D.3
-
51
-
-
0037373316
-
A novel NOD2/CARD15 haplotype conferring risk for Crohn disease in Ashkenazi Jews
-
Sugimura K., Taylor K., Lin Y., et al. A novel NOD2/CARD15 haplotype conferring risk for Crohn disease in Ashkenazi Jews. Am J Hum Genet 72 (2003) 509-518
-
(2003)
Am J Hum Genet
, vol.72
, pp. 509-518
-
-
Sugimura, K.1
Taylor, K.2
Lin, Y.3
-
52
-
-
11144279151
-
Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis
-
Economou M., Trikalinos T., Loizou K., Tsianos E., and Ioannidis J. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol 99 (2004) 2393-2404
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 2393-2404
-
-
Economou, M.1
Trikalinos, T.2
Loizou, K.3
Tsianos, E.4
Ioannidis, J.5
-
53
-
-
10744230291
-
Defining complex contributions of NOD2/CARD15 gene mutations, age at onset, and tobacco use on Crohn's disease phenotypes
-
Brant S., Picco M., Achkar J., et al. Defining complex contributions of NOD2/CARD15 gene mutations, age at onset, and tobacco use on Crohn's disease phenotypes. Inflamm Bowel Dis 9 (2003) 281-289
-
(2003)
Inflamm Bowel Dis
, vol.9
, pp. 281-289
-
-
Brant, S.1
Picco, M.2
Achkar, J.3
-
54
-
-
0037062228
-
Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study
-
Hampe J., Grebe J., Nikolaus S., et al. Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study. Lancet 359 (2002) 1661-1665
-
(2002)
Lancet
, vol.359
, pp. 1661-1665
-
-
Hampe, J.1
Grebe, J.2
Nikolaus, S.3
-
55
-
-
0012135426
-
3020insC mutation within the NOD2 gene in Crohn's disease: frequency and association with clinical pattern in an Italian population
-
Vavassori P., Borgiani P., D'Apice M., et al. 3020insC mutation within the NOD2 gene in Crohn's disease: frequency and association with clinical pattern in an Italian population. Dig Liver Dis 34 (2002) 153
-
(2002)
Dig Liver Dis
, vol.34
, pp. 153
-
-
Vavassori, P.1
Borgiani, P.2
D'Apice, M.3
-
56
-
-
0036080129
-
The c-insertion mutation of the NOD2 gene is associated with fistulizing and fibrostenotic phenotypes in Crohn's disease
-
Radlmayr M., Torok H., Martin K., and Folwaczny C. The c-insertion mutation of the NOD2 gene is associated with fistulizing and fibrostenotic phenotypes in Crohn's disease. Gastroenterology 122 (2002) 2091-2092
-
(2002)
Gastroenterology
, vol.122
, pp. 2091-2092
-
-
Radlmayr, M.1
Torok, H.2
Martin, K.3
Folwaczny, C.4
-
57
-
-
0036725827
-
Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease
-
Abreu M., Taylor K., Lin Y., et al. Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease. Gastroenterology 123 (2002) 679-688
-
(2002)
Gastroenterology
, vol.123
, pp. 679-688
-
-
Abreu, M.1
Taylor, K.2
Lin, Y.3
-
58
-
-
9144271221
-
CARD15 gene mutations and risk for early surgery in pediatric-onset Crohn's disease
-
Kugathasan S., Collins N., Maresso K., et al. CARD15 gene mutations and risk for early surgery in pediatric-onset Crohn's disease. Clin Gastroenterol Hepatol 2 (2004) 1003-1009
-
(2004)
Clin Gastroenterol Hepatol
, vol.2
, pp. 1003-1009
-
-
Kugathasan, S.1
Collins, N.2
Maresso, K.3
-
59
-
-
1542540219
-
CARD15 genotype and phenotype analysis in 55 pediatric patients with crohn disease from Saxony, Germany
-
Sun L., Roesler J., Rosen-Wolff A., et al. CARD15 genotype and phenotype analysis in 55 pediatric patients with crohn disease from Saxony, Germany. J Pediatr Gastroenterol Nutr 37 (2003) 492-497
-
(2003)
J Pediatr Gastroenterol Nutr
, vol.37
, pp. 492-497
-
-
Sun, L.1
Roesler, J.2
Rosen-Wolff, A.3
-
60
-
-
0036061640
-
Long-term evolution of disease behavior of Crohn's disease
-
Cosnes J., Cattan S., Blain A., et al. Long-term evolution of disease behavior of Crohn's disease. Inflamm Bowel Dis 8 (2002) 244-250
-
(2002)
Inflamm Bowel Dis
, vol.8
, pp. 244-250
-
-
Cosnes, J.1
Cattan, S.2
Blain, A.3
-
61
-
-
18644366895
-
Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: an analysis in 534 patients from two multicenter, prospective GCP-level trials
-
Mascheretti S., Hampe J., Croucher P., et al. Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: an analysis in 534 patients from two multicenter, prospective GCP-level trials. Pharmacogenetics 12 (2002) 509-515
-
(2002)
Pharmacogenetics
, vol.12
, pp. 509-515
-
-
Mascheretti, S.1
Hampe, J.2
Croucher, P.3
-
62
-
-
0036305537
-
NOD2/CARD15 does not influence response to infliximab in Crohn's disease
-
Vermeire S., Louis E., Rutgeerts P., et al. NOD2/CARD15 does not influence response to infliximab in Crohn's disease. Gastroenterology 123 (2002) 106-111
-
(2002)
Gastroenterology
, vol.123
, pp. 106-111
-
-
Vermeire, S.1
Louis, E.2
Rutgeerts, P.3
-
63
-
-
0037108346
-
Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains
-
Harton J., Linhoff M., Zhang J., and Ting J. Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains. J Immunol 169 (2002) 4088-4093
-
(2002)
J Immunol
, vol.169
, pp. 4088-4093
-
-
Harton, J.1
Linhoff, M.2
Zhang, J.3
Ting, J.4
-
65
-
-
19944431022
-
Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-(kappa)B activation: common genetic etiology with Blau syndrome
-
Kanazawa N., Okafuji I., Kambe N., et al. Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-(kappa)B activation: common genetic etiology with Blau syndrome. Blood 105 (2005) 1195-1197
-
(2005)
Blood
, vol.105
, pp. 1195-1197
-
-
Kanazawa, N.1
Okafuji, I.2
Kambe, N.3
-
66
-
-
0035951792
-
Human Nod1 confers responsiveness to bacterial lipopolysaccharides
-
Inohara N., Ogura Y., Chen F., Muto A., and Nunez G. Human Nod1 confers responsiveness to bacterial lipopolysaccharides. J Biol Chem 276 (2001) 2551-2554
-
(2001)
J Biol Chem
, vol.276
, pp. 2551-2554
-
-
Inohara, N.1
Ogura, Y.2
Chen, F.3
Muto, A.4
Nunez, G.5
-
67
-
-
0012722659
-
NOD2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
Girardin S., Boneca I., Viala J., et al. NOD2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 278 (2003) 8869-8872
-
(2003)
J Biol Chem
, vol.278
, pp. 8869-8872
-
-
Girardin, S.1
Boneca, I.2
Viala, J.3
-
68
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara N., Ogura Y., Fontalba A., et al. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 278 (2003) 5509-5512
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
-
69
-
-
4444253690
-
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
-
Watanabe T., Kitani A., Murray P., and Strober W. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nature Immunol 5 (2004) 800-808
-
(2004)
Nature Immunol
, vol.5
, pp. 800-808
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.3
Strober, W.4
-
70
-
-
13244292161
-
NOD2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi K., Chamaillard M., Ogura Y., et al. NOD2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307 (2005) 731-734
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.1
Chamaillard, M.2
Ogura, Y.3
-
71
-
-
13244277880
-
NOD2 mutation in Crohn's disease potentiates NF-κB activity and IL-1β processing
-
Maeda S., Hsu L., Liu H., et al. NOD2 mutation in Crohn's disease potentiates NF-κB activity and IL-1β processing. Science 307 (2005) 734-738
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.2
Liu, H.3
-
72
-
-
4444332518
-
Regulation of IL-8 and IL-1β expression in Crohn's disease associated NOD2/CARD15 mutations
-
Li J., Moran T., Swanson E., et al. Regulation of IL-8 and IL-1β expression in Crohn's disease associated NOD2/CARD15 mutations. Hum Mol Genet 13 (2004) 1715-1725
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1715-1725
-
-
Li, J.1
Moran, T.2
Swanson, E.3
-
73
-
-
3442899939
-
NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease
-
Netea M., Kullberg B., de Jong D., et al. NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease. Eur J Immunol 34 (2004) 2052-2059
-
(2004)
Eur J Immunol
, vol.34
, pp. 2052-2059
-
-
Netea, M.1
Kullberg, B.2
de Jong, D.3
-
74
-
-
21144468350
-
Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease
-
van Heel D., Ghosh S., Butler M., et al. Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease. Lancet 365 (2005) 1794-1796
-
(2005)
Lancet
, vol.365
, pp. 1794-1796
-
-
van Heel, D.1
Ghosh, S.2
Butler, M.3
-
75
-
-
2342583513
-
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
-
Tanabe T., Chamaillard M., Ogura Y., et al. Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition. EMBO J 23 (2004) 1587-1597
-
(2004)
EMBO J
, vol.23
, pp. 1587-1597
-
-
Tanabe, T.1
Chamaillard, M.2
Ogura, Y.3
-
76
-
-
7644234401
-
hPepT1 transports muramyl dipeptide, activating NF-κB and stimulating IL-8 secretion in human colonic Caco2/bbe cells
-
Vavricka S., Musch M., Chang J., et al. hPepT1 transports muramyl dipeptide, activating NF-κB and stimulating IL-8 secretion in human colonic Caco2/bbe cells. Gastroenterology 127 (2004) 1401-1409
-
(2004)
Gastroenterology
, vol.127
, pp. 1401-1409
-
-
Vavricka, S.1
Musch, M.2
Chang, J.3
-
77
-
-
0036828844
-
Induction of NOD2 in myelomonocytic and intestinal epithelial cells via nuclear factor-kappa B activation
-
Gutierrez O., Pipaon C., Inohara N., et al. Induction of NOD2 in myelomonocytic and intestinal epithelial cells via nuclear factor-kappa B activation. J Biol Chem 277 (2002) 41701-41705
-
(2002)
J Biol Chem
, vol.277
, pp. 41701-41705
-
-
Gutierrez, O.1
Pipaon, C.2
Inohara, N.3
-
78
-
-
0038109983
-
Crohn's disease and the NOD2 gene: a role for Paneth cells
-
Lala S., Ogura Y., Osborne C., et al. Crohn's disease and the NOD2 gene: a role for Paneth cells. Gastroenterology 125 (2003) 47-57
-
(2003)
Gastroenterology
, vol.125
, pp. 47-57
-
-
Lala, S.1
Ogura, Y.2
Osborne, C.3
-
79
-
-
0034252293
-
Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria
-
Ayabe T., Satchell D., Wilson C., Parks W., Selsted M., and Ouellette A. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nat Immunol 1 (2000) 113-118
-
(2000)
Nat Immunol
, vol.1
, pp. 113-118
-
-
Ayabe, T.1
Satchell, D.2
Wilson, C.3
Parks, W.4
Selsted, M.5
Ouellette, A.6
-
80
-
-
0033213989
-
Epithelial antimicrobial peptides: innate local host response elements
-
Schroder J. Epithelial antimicrobial peptides: innate local host response elements. Cell Mol Life Sci 56 (1999) 32-46
-
(1999)
Cell Mol Life Sci
, vol.56
, pp. 32-46
-
-
Schroder, J.1
-
81
-
-
0037417311
-
Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin
-
Salzman N., Ghosh D., Huttner K., Paterson Y., and Bevins C. Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin. Nature 422 (2003) 522-526
-
(2003)
Nature
, vol.422
, pp. 522-526
-
-
Salzman, N.1
Ghosh, D.2
Huttner, K.3
Paterson, Y.4
Bevins, C.5
-
82
-
-
29144483937
-
Reduced Paneth cell alpha-defensins in ileal Crohn's disease
-
Wehkamp J., Salzman N., Porter E., et al. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci USA 102 (2005) 18129-18134
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18129-18134
-
-
Wehkamp, J.1
Salzman, N.2
Porter, E.3
-
83
-
-
7244257312
-
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression
-
Wehkamp J., Harder J., Weichenthal M., et al. NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression. Gut 53 (2004) 1658-1664
-
(2004)
Gut
, vol.53
, pp. 1658-1664
-
-
Wehkamp, J.1
Harder, J.2
Weichenthal, M.3
-
84
-
-
4644249955
-
NFκB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium
-
Wehkamp J., Harder J., Wehkamp K., et al. NFκB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium. Infect Immun 72 (2004) 5750-5758
-
(2004)
Infect Immun
, vol.72
, pp. 5750-5758
-
-
Wehkamp, J.1
Harder, J.2
Wehkamp, K.3
-
85
-
-
33646003271
-
A flow cytometric assay to monitor antimicrobial activity of defensins and cationic tissue extracts
-
published online Sept 22. DOI: 10.1016/j.mimet.2005.08.004
-
Nuding S., Fellerman K., Wehkamp J., Mueller H., and Stange E. A flow cytometric assay to monitor antimicrobial activity of defensins and cationic tissue extracts. J Microbiol Meth (2005). published online Sept 22. DOI: 10.1016/j.mimet.2005.08.004
-
(2005)
J Microbiol Meth
-
-
Nuding, S.1
Fellerman, K.2
Wehkamp, J.3
Mueller, H.4
Stange, E.5
-
86
-
-
0037380969
-
CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells
-
Hisamatsu T., Suzuki M., Reinecker H., Nadeau W., McCormick B., and Podolsky D. CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells. Gastroenterology 124 (2003) 993-1000
-
(2003)
Gastroenterology
, vol.124
, pp. 993-1000
-
-
Hisamatsu, T.1
Suzuki, M.2
Reinecker, H.3
Nadeau, W.4
McCormick, B.5
Podolsky, D.6
-
87
-
-
0032437063
-
Cytokine gene transcription by NF-κB family members in patients with inflammatory bowel disease
-
Neurath M., Fuss I., Schurmann G., et al. Cytokine gene transcription by NF-κB family members in patients with inflammatory bowel disease. Ann N Y Acad Sci 859 (1998) 149-159
-
(1998)
Ann N Y Acad Sci
, vol.859
, pp. 149-159
-
-
Neurath, M.1
Fuss, I.2
Schurmann, G.3
-
88
-
-
0037452968
-
Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases
-
Chamaillard M., Philpott D., Girardin S., et al. Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases. Proc Natl Acad Sci USA 100 (2003) 3455-3460
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3455-3460
-
-
Chamaillard, M.1
Philpott, D.2
Girardin, S.3
-
89
-
-
0041827164
-
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation
-
Chamaillard M., Girardin S., Viala J., and Philpott D. Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation. Cell Microbiol 5 (2003) 581-592
-
(2003)
Cell Microbiol
, vol.5
, pp. 581-592
-
-
Chamaillard, M.1
Girardin, S.2
Viala, J.3
Philpott, D.4
-
90
-
-
0037043658
-
Inflammatory bowel disease
-
Podolsky D. Inflammatory bowel disease. N Engl J Med 347 (2002) 417-429
-
(2002)
N Engl J Med
, vol.347
, pp. 417-429
-
-
Podolsky, D.1
-
91
-
-
0142123222
-
Role of Nod2 in the response of macrophages to toll-like receptor agonists
-
Pauleau A., and Murray P. Role of Nod2 in the response of macrophages to toll-like receptor agonists. Mol Cell Biol 23 (2003) 7531-7539
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7531-7539
-
-
Pauleau, A.1
Murray, P.2
-
92
-
-
27444444603
-
Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease
-
van Heel D., Ghosh S., Hunt K., et al. Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease. Gut 54 (2005) 1553-1557
-
(2005)
Gut
, vol.54
, pp. 1553-1557
-
-
van Heel, D.1
Ghosh, S.2
Hunt, K.3
-
93
-
-
20844454920
-
Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release
-
Netea M., Ferwerda G., de Jong D., et al. Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release. J Immunol 174 (2005) 6518-6523
-
(2005)
J Immunol
, vol.174
, pp. 6518-6523
-
-
Netea, M.1
Ferwerda, G.2
de Jong, D.3
-
94
-
-
20444486755
-
GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells
-
Barnich N., Hisamatsu T., Aguirre J., Xavier R., Reinecker H., and Podolsky D. GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells. J Biol Chem 280 (2005) 19021-19026
-
(2005)
J Biol Chem
, vol.280
, pp. 19021-19026
-
-
Barnich, N.1
Hisamatsu, T.2
Aguirre, J.3
Xavier, R.4
Reinecker, H.5
Podolsky, D.6
-
95
-
-
11144289688
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
-
Abbott D., Wilkins A., Asara J., and Cantley L. The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr Biol 14 (2004) 2217-2227
-
(2004)
Curr Biol
, vol.14
, pp. 2217-2227
-
-
Abbott, D.1
Wilkins, A.2
Asara, J.3
Cantley, L.4
-
96
-
-
12444259829
-
Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human monocytic cells in culture
-
Uehara A., Yang S., Fujimoto Y., et al. Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human monocytic cells in culture. Cell Microbiol 7 (2005) 53-61
-
(2005)
Cell Microbiol
, vol.7
, pp. 53-61
-
-
Uehara, A.1
Yang, S.2
Fujimoto, Y.3
-
97
-
-
0035078190
-
Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture
-
Yang S., Tamai R., Akashi S., et al. Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture. Infect Immun 69 (2001) 2045-2053
-
(2001)
Infect Immun
, vol.69
, pp. 2045-2053
-
-
Yang, S.1
Tamai, R.2
Akashi, S.3
-
98
-
-
1542275510
-
Structural requirements of synthetic muropeptides to synergize with lipopolysaccharide in cytokine induction
-
Traub S., Kubasch N., Morath S., et al. Structural requirements of synthetic muropeptides to synergize with lipopolysaccharide in cytokine induction. J Biol Chem 279 (2004) 8694-8700
-
(2004)
J Biol Chem
, vol.279
, pp. 8694-8700
-
-
Traub, S.1
Kubasch, N.2
Morath, S.3
-
99
-
-
27444433978
-
NOD2 regulation of Toll-like receptor responses and the pathogenesis of Crohn's disease
-
Watanabe T., Kitani A., and Strober W. NOD2 regulation of Toll-like receptor responses and the pathogenesis of Crohn's disease. Gut 54 (2005) 1515-1518
-
(2005)
Gut
, vol.54
, pp. 1515-1518
-
-
Watanabe, T.1
Kitani, A.2
Strober, W.3
-
100
-
-
33244472793
-
Signalling pathways and molecular interactions of NOD1 and NOD2
-
Strober W., Murray P., Kitani A., et al. Signalling pathways and molecular interactions of NOD1 and NOD2. Nat Rev Immunol 6 (2006) 9-20
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 9-20
-
-
Strober, W.1
Murray, P.2
Kitani, A.3
-
101
-
-
0032786521
-
HLA-DR and -DQ phenotypes in inflammatory bowel disease: a meta-analysis
-
Stokkers P., Reitsma P., Tytgat G., and van Deventer S. HLA-DR and -DQ phenotypes in inflammatory bowel disease: a meta-analysis. Gut 45 (1999) 395-401
-
(1999)
Gut
, vol.45
, pp. 395-401
-
-
Stokkers, P.1
Reitsma, P.2
Tytgat, G.3
van Deventer, S.4
-
102
-
-
17944378525
-
Replication and extension studies of inflammatory bowel disease susceptibility regions confirm linkage to chromosome 6p (IBD3)
-
Dechairo B., Dimon C., van Heel D., et al. Replication and extension studies of inflammatory bowel disease susceptibility regions confirm linkage to chromosome 6p (IBD3). Eur J Hum Genet 9 (2001) 627-633
-
(2001)
Eur J Hum Genet
, vol.9
, pp. 627-633
-
-
Dechairo, B.1
Dimon, C.2
van Heel, D.3
-
103
-
-
0032926240
-
Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analyses
-
Yang H., Plevy S., Taylor K., et al. Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analyses. Gut 44 (1999) 519-526
-
(1999)
Gut
, vol.44
, pp. 519-526
-
-
Yang, H.1
Plevy, S.2
Taylor, K.3
-
104
-
-
85047697768
-
Sex stratification of an inflammatory bowel disease genome search shows male-specific linkage to the HLA region of chromosome 6
-
Fisher S., Hampe J., Macpherson A., et al. Sex stratification of an inflammatory bowel disease genome search shows male-specific linkage to the HLA region of chromosome 6. Eur J Hum Genet 10 (2002) 259-265
-
(2002)
Eur J Hum Genet
, vol.10
, pp. 259-265
-
-
Fisher, S.1
Hampe, J.2
Macpherson, A.3
-
105
-
-
0033910870
-
Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci
-
Rioux J., Silverberg M., Daly M., et al. Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. Am J Hum Genet 66 (2000) 1863-1870
-
(2000)
Am J Hum Genet
, vol.66
, pp. 1863-1870
-
-
Rioux, J.1
Silverberg, M.2
Daly, M.3
-
106
-
-
0030912011
-
Genetic markers may predict disease behavior in patients with ulcerative colitis
-
Roussomoustakaki M., Satsangi J., Welsh K., et al. Genetic markers may predict disease behavior in patients with ulcerative colitis. Gastroenterology 112 (1997) 1845-1853
-
(1997)
Gastroenterology
, vol.112
, pp. 1845-1853
-
-
Roussomoustakaki, M.1
Satsangi, J.2
Welsh, K.3
-
107
-
-
0037242317
-
Clinical and genetic heterogeneity in Mexican patients with ulcerative colitis
-
Yamamoto-Furusho J., Uscanga L., Vargas-Alarcon G., et al. Clinical and genetic heterogeneity in Mexican patients with ulcerative colitis. Hum Immunol 64 (2003) 119-123
-
(2003)
Hum Immunol
, vol.64
, pp. 119-123
-
-
Yamamoto-Furusho, J.1
Uscanga, L.2
Vargas-Alarcon, G.3
-
108
-
-
0033993733
-
HLA class II haplotype associations with inflammatory bowel disease in Jewish (Ashkenazi) and non-Jewish caucasian populations
-
Trachtenberg E., Yang H., Hayes E., et al. HLA class II haplotype associations with inflammatory bowel disease in Jewish (Ashkenazi) and non-Jewish caucasian populations. Hum Immunol 61 (2000) 326-333
-
(2000)
Hum Immunol
, vol.61
, pp. 326-333
-
-
Trachtenberg, E.1
Yang, H.2
Hayes, E.3
-
109
-
-
0037239677
-
A population- and family-based study of Canadian families reveals association of HLA DRB1*0103 with colonic involvement in inflammatory bowel disease
-
Silverberg M., Mirea L., Bull S., et al. A population- and family-based study of Canadian families reveals association of HLA DRB1*0103 with colonic involvement in inflammatory bowel disease. Inflamm Bowel Dis 9 (2003) 1-9
-
(2003)
Inflamm Bowel Dis
, vol.9
, pp. 1-9
-
-
Silverberg, M.1
Mirea, L.2
Bull, S.3
-
110
-
-
0033973568
-
Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease
-
Orchard T., Thiyagaraja S., Welsh K., Wordsworth B., Hill Gaston J., and Jewell D. Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease. Gastroenterology 118 (2000) 274-278
-
(2000)
Gastroenterology
, vol.118
, pp. 274-278
-
-
Orchard, T.1
Thiyagaraja, S.2
Welsh, K.3
Wordsworth, B.4
Hill Gaston, J.5
Jewell, D.6
-
111
-
-
0036731117
-
Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes
-
Orchard T., Chua C., Ahmad T., Cheng H., Welsh K., and Jewell D. Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes. Gastroenterology 123 (2002) 714-718
-
(2002)
Gastroenterology
, vol.123
, pp. 714-718
-
-
Orchard, T.1
Chua, C.2
Ahmad, T.3
Cheng, H.4
Welsh, K.5
Jewell, D.6
-
112
-
-
0025164308
-
The incidence of ulcerative colitis in Northern Norway from 1983 to 1986. The Northern Norwegian Gastroenterology Society
-
Kildebo S., Nordgaard K., Aronsen O., Breckan R., Burhol P., and Jorde R. The incidence of ulcerative colitis in Northern Norway from 1983 to 1986. The Northern Norwegian Gastroenterology Society. Scand J Gastroenterol 25 (1990) 890-896
-
(1990)
Scand J Gastroenterol
, vol.25
, pp. 890-896
-
-
Kildebo, S.1
Nordgaard, K.2
Aronsen, O.3
Breckan, R.4
Burhol, P.5
Jorde, R.6
-
113
-
-
0018289830
-
National Cooperative Crohn's Disease Study: extraintestinal manifestations and perianal complications
-
Rankin G., Watts H., Melnyk C., and Kelley Jr. M. National Cooperative Crohn's Disease Study: extraintestinal manifestations and perianal complications. Gastroenterology 77 (1979) 914-920
-
(1979)
Gastroenterology
, vol.77
, pp. 914-920
-
-
Rankin, G.1
Watts, H.2
Melnyk, C.3
Kelley Jr., M.4
-
114
-
-
0345688816
-
The contribution of human leucocyte antigen complex genes to disease phenotype in ulcerative colitis
-
Ahmad T., Armuzzi A., Neville M., et al. The contribution of human leucocyte antigen complex genes to disease phenotype in ulcerative colitis. Tissue Antigens 62 (2003) 527-535
-
(2003)
Tissue Antigens
, vol.62
, pp. 527-535
-
-
Ahmad, T.1
Armuzzi, A.2
Neville, M.3
-
115
-
-
33646058963
-
Tumour necrosis factor α promoter polymorphisms influence disease phenotype and severity in childhood inflammatory bowel disease
-
Van Limbergen J., Russell R., Nimmo E., et al. Tumour necrosis factor α promoter polymorphisms influence disease phenotype and severity in childhood inflammatory bowel disease. Gut 55 suppl 2 (2006) A10
-
(2006)
Gut
, vol.55
, Issue.SUPPL. 2
-
-
Van Limbergen, J.1
Russell, R.2
Nimmo, E.3
-
116
-
-
0142138025
-
Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease
-
Negoro K., McGovern D., Kinouchi Y., et al. Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease. Gut 52 (2003) 541-546
-
(2003)
Gut
, vol.52
, pp. 541-546
-
-
Negoro, K.1
McGovern, D.2
Kinouchi, Y.3
-
117
-
-
0037622913
-
Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31
-
Armuzzi A., Ahmad T., Ling K., et al. Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31. Gut 52 (2003) 1133-1139
-
(2003)
Gut
, vol.52
, pp. 1133-1139
-
-
Armuzzi, A.1
Ahmad, T.2
Ling, K.3
-
118
-
-
0038389762
-
IBD5 is a general risk factor for inflammatory bowel disease: replication of association with Crohn disease and identification of a novel association with ulcerative colitis
-
Giallourakis C., Stoll M., Miller K., et al. IBD5 is a general risk factor for inflammatory bowel disease: replication of association with Crohn disease and identification of a novel association with ulcerative colitis. Am J Hum Genet 73 (2003) 205-211
-
(2003)
Am J Hum Genet
, vol.73
, pp. 205-211
-
-
Giallourakis, C.1
Stoll, M.2
Miller, K.3
-
119
-
-
0037383554
-
Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease
-
Mirza M., Fisher S., King K., et al. Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease. Am J Hum Genet 72 (2003) 1018-1022
-
(2003)
Am J Hum Genet
, vol.72
, pp. 1018-1022
-
-
Mirza, M.1
Fisher, S.2
King, K.3
-
120
-
-
0347362514
-
Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis
-
McGovern D., Van Heel D., Negoro K., Ahmad T., and Jewell D. Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis. Am J Hum Genet 73 (2003) 1465-1466
-
(2003)
Am J Hum Genet
, vol.73
, pp. 1465-1466
-
-
McGovern, D.1
Van Heel, D.2
Negoro, K.3
Ahmad, T.4
Jewell, D.5
-
121
-
-
0034785352
-
Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
-
Rioux J., Daly M., Silverberg M., et al. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nat Genet 29 (2001) 223-228
-
(2001)
Nat Genet
, vol.29
, pp. 223-228
-
-
Rioux, J.1
Daly, M.2
Silverberg, M.3
-
122
-
-
0034791032
-
Islands of linkage disequilibrium
-
Goldstein D. Islands of linkage disequilibrium. Nat Genet 29 (2001) 109-111
-
(2001)
Nat Genet
, vol.29
, pp. 109-111
-
-
Goldstein, D.1
-
123
-
-
28844509940
-
The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease
-
Noble C., Nimmo E., Drummond H., et al. The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease. Gastroenterology 129 (2005) 1854-1864
-
(2005)
Gastroenterology
, vol.129
, pp. 1854-1864
-
-
Noble, C.1
Nimmo, E.2
Drummond, H.3
-
124
-
-
2442585704
-
Functional variants of OCTN cation transporter genes are associated with Crohn disease
-
Peltekova V., Wintle R., Rubin L., et al. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat Genet 36 (2004) 471-475
-
(2004)
Nat Genet
, vol.36
, pp. 471-475
-
-
Peltekova, V.1
Wintle, R.2
Rubin, L.3
-
125
-
-
0034791035
-
High-resolution haplotype structure in the human genome
-
Daly M., Rioux J., Schaffner S., Hudson T., and Lander E. High-resolution haplotype structure in the human genome. Nat Genet 29 (2001) 229-232
-
(2001)
Nat Genet
, vol.29
, pp. 229-232
-
-
Daly, M.1
Rioux, J.2
Schaffner, S.3
Hudson, T.4
Lander, E.5
-
126
-
-
21344449654
-
Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease
-
Torok H., Glas J., Tonenchi L., et al. Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease. Gut 54 (2005) 1421-1427
-
(2005)
Gut
, vol.54
, pp. 1421-1427
-
-
Torok, H.1
Glas, J.2
Tonenchi, L.3
-
127
-
-
33646779514
-
Evidence for association of OCTN genes and IBD5 with ulcerative colitis
-
published online Dec 16. DOI:10.1136/gut.2005.084574
-
Waller S., Tremelling M., Bredin F., Godfrey L., Howson J., and Parkes M. Evidence for association of OCTN genes and IBD5 with ulcerative colitis. Gut (2005). published online Dec 16. DOI:10.1136/gut.2005.084574
-
(2005)
Gut
-
-
Waller, S.1
Tremelling, M.2
Bredin, F.3
Godfrey, L.4
Howson, J.5
Parkes, M.6
-
128
-
-
28844459843
-
Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but no with susceptibility to IBD
-
Vermeire S., Pierik M., Hiavaty T., et al. Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but no with susceptibility to IBD. Gastroenterology 129 (2005) 1845-1853
-
(2005)
Gastroenterology
, vol.129
, pp. 1845-1853
-
-
Vermeire, S.1
Pierik, M.2
Hiavaty, T.3
-
129
-
-
33646061100
-
Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth parameters in early-onset inflammatory bowel disease
-
published online Feb 9. DOI:10.1136/gut.2005.082107
-
Russell R., Drummond H., Nimmo E., et al. Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth parameters in early-onset inflammatory bowel disease. Gut (2006). published online Feb 9. DOI:10.1136/gut.2005.082107
-
(2006)
Gut
-
-
Russell, R.1
Drummond, H.2
Nimmo, E.3
-
130
-
-
14944356373
-
A risk haplotype in the solute carrier family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease
-
Newman B., Gu X., Wintle R., et al. A risk haplotype in the solute carrier family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease. Gastroenterology 128 (2005) 260-269
-
(2005)
Gastroenterology
, vol.128
, pp. 260-269
-
-
Newman, B.1
Gu, X.2
Wintle, R.3
-
131
-
-
16044373177
-
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12
-
Satsangi J., Parkes M., Louis E., et al. Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nat Genet 14 (1996) 199-202
-
(1996)
Nat Genet
, vol.14
, pp. 199-202
-
-
Satsangi, J.1
Parkes, M.2
Louis, E.3
-
132
-
-
0032534043
-
A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis
-
Panwala C., Jones J., and Viney J. A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. J Immunol 161 (1998) 5733-5744
-
(1998)
J Immunol
, vol.161
, pp. 5733-5744
-
-
Panwala, C.1
Jones, J.2
Viney, J.3
-
133
-
-
4243801613
-
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
-
Schinkel A., Mayer U., Wagenaar E., et al. Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. Proc Natl Acad Sci USA 94 (1997) 4028-4033
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4028-4033
-
-
Schinkel, A.1
Mayer, U.2
Wagenaar, E.3
-
134
-
-
20244386956
-
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
-
Wijnholds J., Evers R., van Leusden M., et al. Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein. Nat Med 3 (1997) 1275-1279
-
(1997)
Nat Med
, vol.3
, pp. 1275-1279
-
-
Wijnholds, J.1
Evers, R.2
van Leusden, M.3
-
135
-
-
15944420336
-
Effects of glucocorticoids on expression of P-glycoprotein and glucocorticoid receptor in the intestinal epithelium
-
Moodie F., Lyons V., Satsangi J., and Seckl J. Effects of glucocorticoids on expression of P-glycoprotein and glucocorticoid receptor in the intestinal epithelium. Gastroenterology 126 (2004) A303
-
(2004)
Gastroenterology
, vol.126
-
-
Moodie, F.1
Lyons, V.2
Satsangi, J.3
Seckl, J.4
-
136
-
-
0038730695
-
Colonic epithelial functional phenotype varies with type and phase of experimental colitis
-
Mizoguchi E., Xavier R., Reinecker H., et al. Colonic epithelial functional phenotype varies with type and phase of experimental colitis. Gastroenterology 125 (2003) 148-161
-
(2003)
Gastroenterology
, vol.125
, pp. 148-161
-
-
Mizoguchi, E.1
Xavier, R.2
Reinecker, H.3
-
137
-
-
0037372982
-
Altered expression and function of P-glycoprotein in dextran sodium sulfate-induced colitis in mice
-
Iizasa H., Genda N., Kitano T., et al. Altered expression and function of P-glycoprotein in dextran sodium sulfate-induced colitis in mice. J Pharm Sci 92 (2003) 569-576
-
(2003)
J Pharm Sci
, vol.92
, pp. 569-576
-
-
Iizasa, H.1
Genda, N.2
Kitano, T.3
-
138
-
-
0037223561
-
Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis
-
Schwab M., Schaeffeler E., Marx C., et al. Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis. Gastroenterology 124 (2003) 26-33
-
(2003)
Gastroenterology
, vol.124
, pp. 26-33
-
-
Schwab, M.1
Schaeffeler, E.2
Marx, C.3
-
139
-
-
0344197096
-
Lack of association between the C3435T MDR1 gene polymorphism and inflammatory bowel disease in two independent Northern European populations
-
Croucher P., Mascheretti S., Foelsch U., Hampe J., and Schreiber S. Lack of association between the C3435T MDR1 gene polymorphism and inflammatory bowel disease in two independent Northern European populations. Gastroenterology 125 (2003) 1919-1920
-
(2003)
Gastroenterology
, vol.125
, pp. 1919-1920
-
-
Croucher, P.1
Mascheretti, S.2
Foelsch, U.3
Hampe, J.4
Schreiber, S.5
-
141
-
-
9144224852
-
MDR1 Ala893 polymorphism is associated with inflammatory bowel disease
-
Brant S., Panhuysen C., Nicolae D., et al. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am J Hum Genet 73 (2003) 1282-1292
-
(2003)
Am J Hum Genet
, vol.73
, pp. 1282-1292
-
-
Brant, S.1
Panhuysen, C.2
Nicolae, D.3
-
142
-
-
8844229534
-
Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis
-
Potocnik U., Ferkolj I., Glavac D., and Dean M. Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis. Genes Immun 5 (2004) 530-539
-
(2004)
Genes Immun
, vol.5
, pp. 530-539
-
-
Potocnik, U.1
Ferkolj, I.2
Glavac, D.3
Dean, M.4
-
143
-
-
14944341671
-
Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis
-
Ho G., Nimmo E., Tenesa A., et al. Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis. Gastroenterology 128 (2005) 288-296
-
(2005)
Gastroenterology
, vol.128
, pp. 288-296
-
-
Ho, G.1
Nimmo, E.2
Tenesa, A.3
-
144
-
-
33144478521
-
The ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach
-
Ho G., Soranzo N., Tenesa A., Goldstein D., and Satsangi J. The ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach. Hum Mol Genet 15 (2006) 797-805
-
(2006)
Hum Mol Genet
, vol.15
, pp. 797-805
-
-
Ho, G.1
Soranzo, N.2
Tenesa, A.3
Goldstein, D.4
Satsangi, J.5
-
145
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F., Tsuruo T., Hamada H., Gottesman M., Pastan I., and Willingham M. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 84 (1987) 7735-7738
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.4
Pastan, I.5
Willingham, M.6
-
146
-
-
0037624566
-
Multidrug resistance 1 gene (P-glycoprotein 170): an important determinant in gastrointestinal disease?
-
Ho G., Moodie F., and Satsangi J. Multidrug resistance 1 gene (P-glycoprotein 170): an important determinant in gastrointestinal disease?. Gut 52 (2003) 759-766
-
(2003)
Gut
, vol.52
, pp. 759-766
-
-
Ho, G.1
Moodie, F.2
Satsangi, J.3
-
147
-
-
3242735503
-
Loss of detoxification in inflammatory bowel disease: dysregulation of pregnane X receptor target genes
-
Langmann T., Moehle C., Mauerer R., et al. Loss of detoxification in inflammatory bowel disease: dysregulation of pregnane X receptor target genes. Gastroenterology 127 (2004) 26-40
-
(2004)
Gastroenterology
, vol.127
, pp. 26-40
-
-
Langmann, T.1
Moehle, C.2
Mauerer, R.3
-
148
-
-
2442519456
-
Genetic variation in DLG5 is associated with inflammatory bowel disease
-
Stoll M., Corneliussen B., Costello C., et al. Genetic variation in DLG5 is associated with inflammatory bowel disease. Nat Genet 36 (2004) 476-480
-
(2004)
Nat Genet
, vol.36
, pp. 476-480
-
-
Stoll, M.1
Corneliussen, B.2
Costello, C.3
-
149
-
-
0030823372
-
Clustering of increased small intestinal permeability in families with Crohn's disease
-
Peeters M., Geypens B., Claus D., et al. Clustering of increased small intestinal permeability in families with Crohn's disease. Gastroenterology 113 (1997) 802-807
-
(1997)
Gastroenterology
, vol.113
, pp. 802-807
-
-
Peeters, M.1
Geypens, B.2
Claus, D.3
-
150
-
-
21744442434
-
Association of DLG5 R30Q variant with inflammatory bowel disease
-
Daly M., Pearce A., Farwell L., et al. Association of DLG5 R30Q variant with inflammatory bowel disease. Eur J Hum Gen 13 (2005) 835-839
-
(2005)
Eur J Hum Gen
, vol.13
, pp. 835-839
-
-
Daly, M.1
Pearce, A.2
Farwell, L.3
-
151
-
-
21344435414
-
DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population
-
Noble C., Nimmo E., Drummond H., Smith L., Arnott I., and Satsangi J. DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population. Gut 54 (2005) 1416-1420
-
(2005)
Gut
, vol.54
, pp. 1416-1420
-
-
Noble, C.1
Nimmo, E.2
Drummond, H.3
Smith, L.4
Arnott, I.5
Satsangi, J.6
-
152
-
-
33645789855
-
DLG5 variants contribute to Crohn's disease risk in a Canadian population
-
published online Jan 31. DOI 10.1002/humu.20301
-
Newman W., Gu X., Wintle R., et al. DLG5 variants contribute to Crohn's disease risk in a Canadian population. Hum Mutat (2006). published online Jan 31. DOI 10.1002/humu.20301
-
(2006)
Hum Mutat
-
-
Newman, W.1
Gu, X.2
Wintle, R.3
-
153
-
-
33646063245
-
Genotype-phenotype analyses of the IBD susceptibility gene DLG5
-
Cummings J., Herrlinger K., Ahmad T., and Jewell D. Genotype-phenotype analyses of the IBD susceptibility gene DLG5. Gut 54 (2005) 360
-
(2005)
Gut
, vol.54
, pp. 360
-
-
Cummings, J.1
Herrlinger, K.2
Ahmad, T.3
Jewell, D.4
-
154
-
-
31544455376
-
The Dlg 5-113a mutation is associated with susceptibility to early onset inflammatory bowel disease and demonstrates a complex genotype phenotype relationship
-
Russell R., Drummond H., Nimmo E., et al. The Dlg 5-113a mutation is associated with susceptibility to early onset inflammatory bowel disease and demonstrates a complex genotype phenotype relationship. J Pediatr Gastroenterol Nutr 40 (2005) 641-642
-
(2005)
J Pediatr Gastroenterol Nutr
, vol.40
, pp. 641-642
-
-
Russell, R.1
Drummond, H.2
Nimmo, E.3
-
155
-
-
25444483354
-
The promise and perils of interpreting genetic associations in Crohn's disease
-
Trinh T., and Rioux J. The promise and perils of interpreting genetic associations in Crohn's disease. Gut 54 (2005) 1354-1357
-
(2005)
Gut
, vol.54
, pp. 1354-1357
-
-
Trinh, T.1
Rioux, J.2
-
156
-
-
33645012263
-
Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implications of an association with Crohn's disease in men
-
published online Jan 31. DOI: 10.1007/s00439-006-0133-1
-
Friedrichs F., Brescianini S., Annere V., et al. Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implications of an association with Crohn's disease in men. Hum Genet (2006). published online Jan 31. DOI: 10.1007/s00439-006-0133-1
-
(2006)
Hum Genet
-
-
Friedrichs, F.1
Brescianini, S.2
Annere, V.3
-
157
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum S., Paglino J., Eslami-Varzaneh F., Edberg S., and Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118 (2004) 229-241
-
(2004)
Cell
, vol.118
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
158
-
-
0042405132
-
Recognition of microbial infection by Toll-like receptors
-
Kopp E., and Medzhitov R. Recognition of microbial infection by Toll-like receptors. Curr Opin Immunol 15 (2003) 396-401
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 396-401
-
-
Kopp, E.1
Medzhitov, R.2
-
159
-
-
0034445697
-
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
-
Cario E., and Podolsky D. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun 68 (2000) 7010-7017
-
(2000)
Infect Immun
, vol.68
, pp. 7010-7017
-
-
Cario, E.1
Podolsky, D.2
-
160
-
-
0034084438
-
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
-
Arbour N., Lorenz E., Schutte B., et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 25 (2000) 187-191
-
(2000)
Nat Genet
, vol.25
, pp. 187-191
-
-
Arbour, N.1
Lorenz, E.2
Schutte, B.3
-
161
-
-
3042521641
-
Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis
-
Franchimont D., Vermeire S., El Housni H., et al. Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut 53 (2004) 987-992
-
(2004)
Gut
, vol.53
, pp. 987-992
-
-
Franchimont, D.1
Vermeire, S.2
El Housni, H.3
-
162
-
-
14544281031
-
The toll-like receptor 4 (TLR4) Asp299Gly polymorphism is associated with colonic localisation of Crohn's disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway
-
Ouburg S., Mallant-Hent R., Crusius J., et al. The toll-like receptor 4 (TLR4) Asp299Gly polymorphism is associated with colonic localisation of Crohn's disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway. Gut 54 (2005) 439-440
-
(2005)
Gut
, vol.54
, pp. 439-440
-
-
Ouburg, S.1
Mallant-Hent, R.2
Crusius, J.3
-
163
-
-
13544276471
-
Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population
-
Gazouli M., Mantzaris G., Kotsinas A., et al. Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population. World J Gastroenterol 11 (2005) 681-685
-
(2005)
World J Gastroenterol
, vol.11
, pp. 681-685
-
-
Gazouli, M.1
Mantzaris, G.2
Kotsinas, A.3
-
164
-
-
2942689466
-
Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis
-
Torok H., Glas J., Tonenchi L., Mussack T., and Folwaczny C. Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis. Clin Immunol 112 (2004) 85-91
-
(2004)
Clin Immunol
, vol.112
, pp. 85-91
-
-
Torok, H.1
Glas, J.2
Tonenchi, L.3
Mussack, T.4
Folwaczny, C.5
-
165
-
-
20144387613
-
Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: phenotype-genotype correlations
-
Lakatos P., Lakatos L., Szalay F., et al. Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: phenotype-genotype correlations. World J Gastroenterol 11 (2005) 1489-1495
-
(2005)
World J Gastroenterol
, vol.11
, pp. 1489-1495
-
-
Lakatos, P.1
Lakatos, L.2
Szalay, F.3
-
166
-
-
20444467612
-
Association between toll-like receptor 4 and inflammatory bowel disease
-
Oostenbrug L., Drenth J., de Jong D., et al. Association between toll-like receptor 4 and inflammatory bowel disease. Inflamm Bowel Dis 11 (2005) 567-575
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 567-575
-
-
Oostenbrug, L.1
Drenth, J.2
de Jong, D.3
-
167
-
-
20844463064
-
A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease
-
Fort M., Mozaffarian A., Stover A., et al. A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease. J Immunol 174 (2005) 6416-6423
-
(2005)
J Immunol
, vol.174
, pp. 6416-6423
-
-
Fort, M.1
Mozaffarian, A.2
Stover, A.3
-
168
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by toll-like receptor 5
-
Hayashi F., Smith K., Ozinsky A., et al. The innate immune response to bacterial flagellin is mediated by toll-like receptor 5. Nature 410 (2001) 1099-1103
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.2
Ozinsky, A.3
-
169
-
-
0030780605
-
The bacterial flagellin gene as a biomarker for detection, population genetics and epidemiological analysis
-
Winstanley C., and Morgan J. The bacterial flagellin gene as a biomarker for detection, population genetics and epidemiological analysis. Microbiology 143 (1997) 3071-3084
-
(1997)
Microbiology
, vol.143
, pp. 3071-3084
-
-
Winstanley, C.1
Morgan, J.2
-
170
-
-
2342646956
-
Bacterial flagellin is a dominant antigen in Crohn disease
-
Lodes M., Cong Y., Elson C., et al. Bacterial flagellin is a dominant antigen in Crohn disease. Infect Immun 113 (2004) 1296-1306
-
(2004)
Infect Immun
, vol.113
, pp. 1296-1306
-
-
Lodes, M.1
Cong, Y.2
Elson, C.3
-
171
-
-
33646443863
-
Common dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and provides protection from Crohn's disease
-
Gerwitz A., Vijay-Kumar M., Swanson E., Duerr R., Brant S., and Cho J. Common dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and provides protection from Crohn's disease. Gastroenterology 128 suppl 2 (2005) A388
-
(2005)
Gastroenterology
, vol.128
, Issue.SUPPL. 2
-
-
Gerwitz, A.1
Vijay-Kumar, M.2
Swanson, E.3
Duerr, R.4
Brant, S.5
Cho, J.6
-
172
-
-
0034623225
-
An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways
-
Inohara N., Koseki T., Lin J., et al. An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways. J Biol Chem 275 (2000) 27823-27831
-
(2000)
J Biol Chem
, vol.275
, pp. 27823-27831
-
-
Inohara, N.1
Koseki, T.2
Lin, J.3
-
173
-
-
0038824980
-
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
-
Chamaillard M., Hashimoto M., Horie Y., et al. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol 4 (2003) 702-707
-
(2003)
Nat Immunol
, vol.4
, pp. 702-707
-
-
Chamaillard, M.1
Hashimoto, M.2
Horie, Y.3
-
174
-
-
1342344961
-
NOD1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors
-
Kim J., Lee S., and Kagnoff M. NOD1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors. Infect Immun 72 (2004) 1487-1495
-
(2004)
Infect Immun
, vol.72
, pp. 1487-1495
-
-
Kim, J.1
Lee, S.2
Kagnoff, M.3
-
175
-
-
0037216611
-
CARD4/NOD1 is not involved in inflammatory bowel disease
-
Zouali H., Lesage S., Merlin F., et al. CARD4/NOD1 is not involved in inflammatory bowel disease. Gut 52 (2003) 71-74
-
(2003)
Gut
, vol.52
, pp. 71-74
-
-
Zouali, H.1
Lesage, S.2
Merlin, F.3
-
176
-
-
19744366535
-
Association between a complex insertion/deletion polymorphism in NOD1(CARD4) and susceptibility to inflammatory bowel disease
-
McGovern D., Hysi P., Ahmad T., et al. Association between a complex insertion/deletion polymorphism in NOD1(CARD4) and susceptibility to inflammatory bowel disease. Hum Mol Genet 14 (2005) 1245-1250
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1245-1250
-
-
McGovern, D.1
Hysi, P.2
Ahmad, T.3
-
177
-
-
20244364812
-
NOD1 variation, immunoglobulin E and asthma
-
Hysi P., Kabesch M., Moffatt M., et al. NOD1 variation, immunoglobulin E and asthma. Hum Mol Genet 14 (2005) 935-941
-
(2005)
Hum Mol Genet
, vol.14
, pp. 935-941
-
-
Hysi, P.1
Kabesch, M.2
Moffatt, M.3
-
178
-
-
23844508543
-
Synergistic enhancement of Toll-like receptor responses by NOD1 activation
-
Van Heel D., Ghosh S., Butler M., et al. Synergistic enhancement of Toll-like receptor responses by NOD1 activation. Eur J Immunol 35 (2005) 2471-2476
-
(2005)
Eur J Immunol
, vol.35
, pp. 2471-2476
-
-
Van Heel, D.1
Ghosh, S.2
Butler, M.3
-
179
-
-
23844521000
-
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists
-
Fritz J., Girardin S., Fitting C., et al. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Eur J Immunol 35 (2005) 2459-2470
-
(2005)
Eur J Immunol
, vol.35
, pp. 2459-2470
-
-
Fritz, J.1
Girardin, S.2
Fitting, C.3
-
180
-
-
0037075551
-
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
-
Kobayashi K., Inohara N., Hernandez L., et al. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 416 (2002) 194-199
-
(2002)
Nature
, vol.416
, pp. 194-199
-
-
Kobayashi, K.1
Inohara, N.2
Hernandez, L.3
-
181
-
-
27744559928
-
The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists
-
Netea M., Ferwerda G., de Jong D., et al. The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists. J Biol Chem 280 (2005) 35859-35867
-
(2005)
J Biol Chem
, vol.280
, pp. 35859-35867
-
-
Netea, M.1
Ferwerda, G.2
de Jong, D.3
-
182
-
-
33646066042
-
Characterization of genotype-phenotype correlations show that the IBD2 susceptibility locus is associated with colonic Crohn's disease and ulcerative colitis
-
Crawford N., Uthoff S., Eichenberger M., et al. Characterization of genotype-phenotype correlations show that the IBD2 susceptibility locus is associated with colonic Crohn's disease and ulcerative colitis. Gastroenterology 124 (2003) A48
-
(2003)
Gastroenterology
, vol.124
-
-
Crawford, N.1
Uthoff, S.2
Eichenberger, M.3
-
183
-
-
3042657319
-
Genome wide scan in a Flemish inflammatory bowel disease population: support for the IBD4 locus, population heterogeneity, and epistasis
-
Vermeire S., Rutgeerts P., Van Steen K., et al. Genome wide scan in a Flemish inflammatory bowel disease population: support for the IBD4 locus, population heterogeneity, and epistasis. Gut 53 (2004) 980-986
-
(2004)
Gut
, vol.53
, pp. 980-986
-
-
Vermeire, S.1
Rutgeerts, P.2
Van Steen, K.3
-
184
-
-
0033927387
-
High-density genome scan in Crohn disease shows confirmed linkage to chromosome 14q11-12
-
Duerr R., Barmada M., Zhang L., Pfutzer R., and Weeks D. High-density genome scan in Crohn disease shows confirmed linkage to chromosome 14q11-12. Am J Hum Genet 66 (2000) 1857-1862
-
(2000)
Am J Hum Genet
, vol.66
, pp. 1857-1862
-
-
Duerr, R.1
Barmada, M.2
Zhang, L.3
Pfutzer, R.4
Weeks, D.5
-
185
-
-
13944273766
-
The IBD international genetics consortium provides further evidence for linkage to IBD4 and shows gene-environment interaction
-
Pierik M., Yang H., Barmada M., et al. The IBD international genetics consortium provides further evidence for linkage to IBD4 and shows gene-environment interaction. Inflamm Bowel Dis 11 (2005) 1-7
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 1-7
-
-
Pierik, M.1
Yang, H.2
Barmada, M.3
-
186
-
-
84894353884
-
Towards an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a working party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg M., Satsangi J., Ahmad T., et al. Towards an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a working party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 19 suppl A (2005) 5-36
-
(2005)
Can J Gastroenterol
, vol.19
, Issue.SUPPL. A
, pp. 5-36
-
-
Silverberg, M.1
Satsangi, J.2
Ahmad, T.3
-
187
-
-
28844507481
-
Understanding association and causality in the genetic studies of inflammatory bowel disease
-
Trinh T., and Rioux J. Understanding association and causality in the genetic studies of inflammatory bowel disease. Gastroenterology 129 (2005) 2106-2109
-
(2005)
Gastroenterology
, vol.129
, pp. 2106-2109
-
-
Trinh, T.1
Rioux, J.2
-
188
-
-
33645144075
-
Association of DLG5 and inflammatory bowel disease across populations
-
published online Jan 4. DOI:10.1038/sj.ejhg.5201516
-
Tenesa A., Noble C., Satsangi J., et al. Association of DLG5 and inflammatory bowel disease across populations. Eur Jnl Hum Genet (2006). published online Jan 4. DOI:10.1038/sj.ejhg.5201516
-
(2006)
Eur Jnl Hum Genet
-
-
Tenesa, A.1
Noble, C.2
Satsangi, J.3
|