Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

Nature

Volumn 422, Issue 6931, 2003, Pages 522-526

  Salzman, Nita H ^a   Ghosh, Dipankar ^b   Huttner, Kenneth M ^c   Paterson, Yvonne ^d   Bevins, Charles L ^b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; CELLS; POLYPEPTIDES;

ANTIBIOTIC PEPTIDES;

CONSERVATION;

ALPHA DEFENSIN; DEFENSIN; HUMAN DEFENSIN 5; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

MEDICINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL VIRULENCE; CELL SPECIFICITY; CONTROLLED STUDY; DNA FLANKING REGION; EFFECTOR CELL; EPITHELIUM CELL; EXON; GENE EXPRESSION REGULATION; HUMAN; IMMUNE RESPONSE; INFECTION PREVENTION; INFECTION RESISTANCE; INTESTINE CRYPT; INTESTINE INFECTION; MOUSE; NONHUMAN; PANETH CELL; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; TRANSGENIC MOUSE;

ANIMALS; ANTI-BACTERIAL AGENTS; BETA-DEFENSINS; GENE EXPRESSION; HUMANS; INTESTINE, SMALL; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PANETH CELLS; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; TRANSGENES;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA; MUS MUSCULUS; NEGIBACTERIA; SALMONELLA TYPHIMURIUM;

EID: 0037417311     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01520     Document Type: Article

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