HLA-DR and -DQ phenotypes in inflammatory bowel disease: A meta-analysis

Gut

Volumn 45, Issue 3, 1999, Pages 395-401

  Stokkers, P C F ^a   Reitsma, P H ^a   Tytgat, G N J ^a   Van Deventer, S J H ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Crohn's disease; HLA DQ; HLA DR; Ulcerative colitis

Indexed keywords

HLA DQ ANTIGEN; HLA DR ANTIGEN;

ANTIGEN SPECIFICITY; ARTICLE; CHROMOSOME 6; ENTERITIS; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HUMAN; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; META ANALYSIS; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL;

EID: 0032786521     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.45.3.395     Document Type: Article

References (48)

1. 1 Duerr RH. Genetics of inflammatory bowel disease. Inflammatory Bowel Disease 1996;2:48-60.
2. 2 Yang H, Rotter JI. Genetic aspects of idiopathic inflammatory bowel disease. In: Kirsner JB, Shorter RG, eds. Inflammatory bowel disease. Baltimore: Williams and Wilkins, 1995:301-31.
3. 3 Brown JH, Jardetzky TS, Gorga JC, et al. Three-dimensional structure of the human class II histocompatibility antigen HLA-DRI. Nature 1993;364:33-9.
4. 4 Jardetzky TS, Brown JH, Gorga JC, et al. Three-dimensional structure of a human class II histocompatibility molecule completed with superantigen. Nature 1994;368:711-18.
5. 5 Nepom GT, Erlich H, MHC class-II molecules and autoimmunity. Annu Rev Immunol 1991;9:493-525.
6. 6 Toyoda H, Wang SJ, Yang HY, et al. Distinct associations of HLA class II genes with inflammatory bowel disease. Gastroenterology 1993;104:741-8.
7. 7 Danze PM, Colomhel JF, Jacquot S, et al. Association of HLA class II genes with susceptibility to Crohn's disease. Gut 1996;39:69-72.
8. 8 Fujita K, Naito S, Okabe N, et al. Immunological studies in Crohn's disease. I. Association with HLA systems in the Japanese. J Clin Lab Immunol 1984;14:99-102.
9. 9 Matake H, Okahe N, Naito S, et al. An HLA study on 149 Japanese patients with Crohn's disease. Gastroenterol Jpn 1992;27:496-501.
10. 10 Kobayashi K, Atoh M, Yagita A, et al. Crohn's disease in the Japanese is associated with the HLA-DRw53. Exp Clin Immunogenet 1990;7:101-8.
11. 11 Remshagen M, Loeliger C, Kuehnl P, et al. HLA class II gene frequencies in Crohn's disease: a population based analysis in Germany. Gut 1996;38:538-42.
12. 12 Caruso C, Oliva L, Palmeri P, et al. B cell alloantigens in Sicilian patients with Crohn's disease. Tissue Antigens 1983; 21:170-2.
13. 13 Forcione DG, Sands B, Isselbacher KJ, et al. An increased risk of Crohn's disease in individuals who inherit the HLA class II DRB3*0301 allele. Proc Natl Acad Sci USA 1996;93:5094-8.
14. 14 Purrmann J, Bertrams J, Knapp M, et al. Gene and haplotype frequencies of HLA antigens in 269 patients with Crohn's disease. Scand J Gastroenterol 1990;25:981-5.
15. 15 Bouma G, Oudkerk Pool M, Crusius JB, et al. Evidence for genetic heterogeneity in inflammatory bowel disease (IBD); HLA genes in the predisposition to suffer from ulcerative colitis (UC) and Crohn's disease (CD). Clin Exp Immunol 1997;109:175-9.
16. 16 Kobayashi K, Atoh M, Konoeda Y, et al. HLA-DR, DQ and T cell antigen receptor constant beta genes in Japanese patients with ulcerative colitis. Clin Exp Immunol 1990;80: 400-3.
17. 17 Sugimura K, Asakura H, Mizuki N, et al. Analysis of genes within the HLA region affecting susceptibility to ulcerative colitis. Hum Immunol 1993;36:112-18.
18. 18 Asakura H, Tsuchiya M, Aiso S, et al. Association of the human lymphocyte-DR2 antigen with Japanese ulcerative colitis. Gastroenterology 1982;82:413-18.
19. 19 Caruso C, Palmeri P, Oliva L, et al. HLA antigens in ulcerative colitis: a study in the Sicilian population. Tissue Antigens 1985;25:47-9.
20. 20 De La Concha EG, Fernandez-Arquero M, Santa-Cruz S, et al. Positive and negative associations of distinct HLA-DR2 subtypes with ulcerative colitis (UC). Clin Exp Immunol 1997;108:392-5.
21. 21 Leidenius MH, Koskimics SA, Kellokumpu IH, et al. HLA antigens in ulcerative colitis and primary sclerosing cholangitis. APMIS 1995;103:519-24.
22. 22 Satsangi J, Welsh KI, Bunce M, et al. Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease. Lancet 1996;347;1212-17.
23. 23 McConnell RB. Ulcerative colitis - genetic features. Scand J Gastroenterol 1983;88(suppl):14-16.
24. 24 Wassmuth R, Kastman S, Kockum I, et al. HLA DR and DQ RFLP analysis in Crohn's disease. Eur J Immunogenet 1993;20:429-33.
25. 25 Nakajima A, Matsuhashi N, Kodama T, et al. HLA-linked susceptibility and resistance genes in Crohn's disease. Gastroenterology 1995;109:1462-7.
26. 26 Cariappa A, Sands B, Forcione D, et al. Analysis of MHC class II DP, DQ and DR alleles in Crohn's disease. Gut 1998;43:210-15.
27. 27 Heresbach D, Alizadeh M, Bretagne JF, et al. Investigation of the association of major histocompatibility complex genes, including HLA class I, class II and TAP genes, with clinical forms of Crohn's disease. Eur J Immunogenet 1996; 23:141-51.
28. 28 Green A. The epidemiologic approach to studies of association between HLA and disease. I. The basic measures, concepts and estimation procedures. Tissue Antigens 1982; 19:245-58.
29. 29 Green A. The epidemiologic approach to studies of association between HLA and disease. II. Estimation of absolute risks, etiologic and preventive fraction. Tissue Antigens 1982;19:259-68.
30. 30 Futami S, Aoyama N, Honsako Y, et al. HLA-DRB1*1502 allele, subtype of DR15, is associated with susceptibility to ulcerative colitis and its progression. Dig Dis Sci 1995;40: 814-18.
31. 31 Smolen JS, Gangl A, Polterauer P, et al. HLA antigens in inflammatory bowel disease. Gastroenterology 1982;82:34-8.
32. 32 Mehal WZ, Lo YM, Wordsworth BP, et al. HLA DR4 is a marker for rapid disease progression in primary sclerosing cholangitis. Gastroenterology 1994;106:160-7.
33. 33 Duerr RH, Neigut DA. Molecularly defined HLA-DR2 alleles in ulcerative colitis and an antineutrophil cytoplasmic antibody-positive subgroup. Gastroenterology 1995;108: 423-7.
34. 34 Cottone M, Bunce M, Taylor CJ, et al. Ulcerative colitis and HLA phenotype. Gut 1985;26:952-4.
35. 35 Roussomoustakaki M, Satsangi J, Welsh K, et al. Genetic markers may predict disease behavior in patients with ulcerative colitis. Gastroenterology 1997;112:1845-53.
36. 36 Duerr RH, Chensy LJ. Associations between HLA-DR alleles amd subsets of ulcerative colitis defined by extent of colitis [abstract]. Gastroenterology 1997;112:A963.
37. 37 Zetterquist H, Broome U, Einarsson K, et al. HLA class II genes in primary sclerosing cholangitis and chronic inflammatory bowel disease: no HLA-DRw52a association in Swedish patients with sclerosing cholangitis. Gut 1992;33: 942-6.
38. 38 Gorski J, Tilanus M, Giphart M, et al. Oligonucleotide genotyping shows that alleles at the HLA-DR beta III locus of the DRw52 supertypic group segregate independently of known DR or Dw specificities. Immunogenetics 1987;25:79-83.
39. 39 Heresbach D, Colombel F, Danze PM, et al. The HLA DRB1*0301-DQB1*0201 haplotype confers protection against inflammatory bowel disease. Am J Gastroenterol 1996;91:1060.
40. 40 Bouma G, Poen AC, Garcia-Gonzalez MA, et al. HLA-DRB1*03, but not the TNFA-308 promoter gene polymorphism, confers protection against fistulising Crohn's disease. Immunogenetics 1998;47:451-5.
41. 41 Hugot JP, Laurent-Puig P, Gower-Rousseau C, et al. Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 1996;379:821-3.
42. 42 Cho JH, Nicolae DL, Gold LH, et al. Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1. Proc Natl Acad Sci USA 1998;95:7502-7.
43. 43 Satsangi J, Parkes M, Louis E, etv al. Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nature Genet 1996;14:199-202.
44. 44 Curran ME, Lau KF, Hampe J, et al. Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16. Gastroenterology 1998;115:1066-71.
45. 45 Duerr RH, Barmada MM, Zhang L, et al. Linkage and association between inflammatory bowel disease and a locus on chromosome 12. Am J Hum Genet 1998;63:95-100.
46. 46 Mirza MM, Lee J, Teare D, et al. Evidence of linkage of the inflammatory bowel disease susceptibility locus on chromosome 16 (IBD1) to ulcerative colitis. J Med Genet 1998; 35:218-21.
47. 47 Brant SR, Fu Y, Fields CT, et al. American families with Crohn's disease have strong evidence for linkage to chromosome 16 but not chromosome 12. Gastroenterology 1998;115:1056-61.
48. 48 Pena AS, Biemond I, Kuiper G, et al. HLA antigen distribution and HLA haplotype segregation in Crohn's disease. Tissue Antigens 1980;16:56-61.