메뉴 건너뛰기




Volumn 3, Issue 11, 1997, Pages 1275-1279

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CELL PROTEIN; ETOPOSIDE; LEUKOTRIENE C4; MULTIDRUG RESISTANCE PROTEIN;

EID: 20244386956     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1197-1275     Document Type: Article
Times cited : (412)

References (29)
  • 1
    • 0003078120 scopus 로고    scopus 로고
    • MRP, mode of action and role in MDR
    • (eds. Gupta, S. & Tsuruo, T) Wiley & Sons, London
    • Zaman, G.J.R. & Borst, P. MRP, mode of action and role in MDR. in Multidrug Resistance in Cancer Cells (eds. Gupta, S. & Tsuruo, T) 95-107 (Wiley & Sons, London, 1996).
    • (1996) Multidrug Resistance in Cancer Cells , pp. 95-107
    • Zaman, G.J.R.1    Borst, P.2
  • 2
    • 0029954845 scopus 로고    scopus 로고
    • Biology of the multidrug resistance-associated protein, MRP
    • Loe, D.W., Deeley, R.G. & Cole, S.P.C. Biology of the multidrug resistance-associated protein, MRP. Eur. J. Cancer 32A, 945-957 (1996).
    • (1996) Eur. J. Cancer , vol.32 A , pp. 945-957
    • Loe, D.W.1    Deeley, R.G.2    Cole, S.P.C.3
  • 3
    • 0027984511 scopus 로고
    • 4 and structurally related conjugates
    • 4 and structurally related conjugates. J. Biol. Chem. 269, 27807-27810 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 27807-27810
    • Leier, I.1
  • 4
    • 0027095653 scopus 로고
    • Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
    • Cole, S.P.C. et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 258, 1650-1654 (1992).
    • (1992) Science , vol.258 , pp. 1650-1654
    • Cole, S.P.C.1
  • 5
    • 0030063480 scopus 로고    scopus 로고
    • Transport of gluthathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
    • Jedlitschky, G. et al. Transport of gluthathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res. 56, 988-994 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 988-994
    • Jedlitschky, G.1
  • 6
    • 9244261944 scopus 로고    scopus 로고
    • Distribution of the multidrug resistance-associated protein (MRP) in normal and malignant human tissues
    • Flens, M.J. et al. Distribution of the multidrug resistance-associated protein (MRP) in normal and malignant human tissues. Am. J. Pathol. 148, 1237-1247 (1996).
    • (1996) Am. J. Pathol. , vol.148 , pp. 1237-1247
    • Flens, M.J.1
  • 7
    • 0026459859 scopus 로고
    • The ATP-dependent glutathione S-conjugate export pump
    • Ishikawa, T. The ATP-dependent glutathione S-conjugate export pump. Trends Biochem. Sci. 17, 463-468 (1992).
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 463-468
    • Ishikawa, T.1
  • 8
    • 0029837624 scopus 로고    scopus 로고
    • MOAT4, a novel multispecific organic-anion transporter for glucuronides and mercapturates in mouse L1210 cells and human erythrocytes
    • Saxena, M. & Henderson, G.B. MOAT4, a novel multispecific organic-anion transporter for glucuronides and mercapturates in mouse L1210 cells and human erythrocytes. Biochem. J. 320, 273-281 (1996).
    • (1996) Biochem. J. , vol.320 , pp. 273-281
    • Saxena, M.1    Henderson, G.B.2
  • 10
    • 0028578004 scopus 로고
    • Overexpression of the gene encoding the multidrug resistance associated protein results in increased ATP-dependent glutathione S-conjugate transport
    • Müller, M. et al. Overexpression of the gene encoding the multidrug resistance associated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc. Natl. Acad. Sci. USA 91, 13033-13037 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 13033-13037
    • Müller, M.1
  • 11
    • 0030570805 scopus 로고    scopus 로고
    • Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP
    • Zaman, G.J.R., Cnubben, N.H.P., Bladeren, P.J., Evers, R. & Borst, P. Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP. FEBS Lett. 391, 126-130 (1996).
    • (1996) FEBS Lett. , vol.391 , pp. 126-130
    • Zaman, G.J.R.1    Cnubben, N.H.P.2    Bladeren, P.J.3    Evers, R.4    Borst, P.5
  • 12
    • 0028567035 scopus 로고
    • The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump
    • Zaman, G.J.R. et al. The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. Proc. Natl. Acad. Sci. USA 91, 8822-8826 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8822-8826
    • Zaman, G.J.R.1
  • 13
    • 0029958285 scopus 로고    scopus 로고
    • Identification of the multidrug-resistance protein (MRP) as the glutathione-S-conjugate export pump of erythrocytes
    • Pulaski, L., Jedlitschy, G., Leier, I., Buchholz, U. & Keppler, D. Identification of the multidrug-resistance protein (MRP) as the glutathione-S-conjugate export pump of erythrocytes. Eur. J. Biochem. 241, 644-648 (1996).
    • (1996) Eur. J. Biochem. , vol.241 , pp. 644-648
    • Pulaski, L.1    Jedlitschy, G.2    Leier, I.3    Buchholz, U.4    Keppler, D.5
  • 15
    • 0027301278 scopus 로고
    • Impaired interleukin-3 response in pim-1-deficient bone marrow-derived mast cells
    • Domen, J. et al. Impaired interleukin-3 response in pim-1-deficient bone marrow-derived mast cells. Blood 82, 1445-152 (1993).
    • (1993) Blood , vol.82 , pp. 1445-2152
    • Domen, J.1
  • 17
    • 0029981430 scopus 로고    scopus 로고
    • Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
    • Paulusma, C.C. et al. Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science 271, 1126-1128 (1996).
    • (1996) Science , vol.271 , pp. 1126-1128
    • Paulusma, C.C.1
  • 18
    • 0029152856 scopus 로고
    • Cysteinyl leukotrienes in asthma: Old mediators up to new tricks
    • Hay, D.W.P., Torphy, T.J. & Undem, B. J. Cysteinyl leukotrienes in asthma: Old mediators up to new tricks. Trends Pharmacol. Sci. 16, 304-309 (1995).
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 304-309
    • Hay, D.W.P.1    Torphy, T.J.2    Undem, B.J.3
  • 19
    • 0027945466 scopus 로고
    • Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene
    • Chen, X.-S., Sheller, J.R., Johnson, E.N. & Funk, C.D. Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature 372, 179-182 (1994).
    • (1994) Nature , vol.372 , pp. 179-182
    • Chen, X.-S.1    Sheller, J.R.2    Johnson, E.N.3    Funk, C.D.4
  • 21
    • 0021957329 scopus 로고
    • Prostaglandin and leukotriene synthesis in mouse ears inflamed by arachidonic acid
    • Opas, E.E., Bonney, R.J. & Humes, J.L. Prostaglandin and leukotriene synthesis in mouse ears inflamed by arachidonic acid. J. Invest. Dermatol. 84, 253-256 (1985).
    • (1985) J. Invest. Dermatol. , vol.84 , pp. 253-256
    • Opas, E.E.1    Bonney, R.J.2    Humes, J.L.3
  • 22
    • 0027960078 scopus 로고
    • Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells
    • Cole, S.P.C. et al. Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells. Cancer Res. 54, 5902-5910 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 5902-5910
    • Cole, S.P.C.1
  • 23
    • 0030450845 scopus 로고    scopus 로고
    • Double knockout of the MRP gene leads to increased drug sensitivity in vitro
    • Lorico, A., Rappa, G., Flavell, R.A. & Sartorelli, A.C. Double knockout of the MRP gene leads to increased drug sensitivity in vitro. Cancer Res. 56, 5351-5355 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 5351-5355
    • Lorico, A.1    Rappa, G.2    Flavell, R.A.3    Sartorelli, A.C.4
  • 24
    • 15844416284 scopus 로고    scopus 로고
    • Coordinated induction of MRP/GS-X pump and γ-glutamylcysteine synthetase by heavy metals in human leukemia cells
    • Ishikawa, T. et al. Coordinated induction of MRP/GS-X pump and γ-glutamylcysteine synthetase by heavy metals in human leukemia cells. J. Biol. Chem. 271, 14981-14988 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 14981-14988
    • Ishikawa, T.1
  • 25
    • 0029095763 scopus 로고
    • Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein
    • Zaman, G.J.R. et al. Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein. Proc. Natl. Acad. Sci. USA 92, 7690-7694 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7690-7694
    • Zaman, G.J.R.1
  • 26
    • 4243801613 scopus 로고    scopus 로고
    • Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
    • Schinkel, A.H. et al. Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. Proc. Natl. Acad. Sci. USA 94, 4028-4033 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4028-4033
    • Schinkel, A.H.1
  • 27
    • 0028229150 scopus 로고
    • Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
    • Schinkel, A.H. et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77, 491-502 (1994).
    • (1994) Cell , vol.77 , pp. 491-502
    • Schinkel, A.H.1
  • 28
    • 0029939542 scopus 로고    scopus 로고
    • Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter
    • Stride, B.D. et al. Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter. Mol. Pharmacol. 49, 962-971 (1996).
    • (1996) Mol. Pharmacol. , vol.49 , pp. 962-971
    • Stride, B.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.