-
1
-
-
0001139444
-
Programmed cell death-I. Cytology of degeneration in the intersegmental muscles of the pernyi silkmoth
-
Lockshin R.A., Williams C.M. Programmed cell death-I. Cytology of degeneration in the intersegmental muscles of the pernyi silkmoth. J Insect Physiol. 11:1965;123-133
-
(1965)
J Insect Physiol
, vol.11
, pp. 123-133
-
-
Lockshin, R.A.1
Williams, C.M.2
-
2
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr J.F., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer. 26:1972;239-257
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
6
-
-
0027535559
-
Toward an understanding of the molecular mechanisms of physiological cell death
-
Vaux D.L. Toward an understanding of the molecular mechanisms of physiological cell death. Proc Natl Acad Sci USA. 90:1993;786-789
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 786-789
-
-
Vaux, D.L.1
-
7
-
-
0022497852
-
Genetic control of programmed cell death in the nematode C. elegans
-
Ellis H.M., Horvitz H.R. Genetic control of programmed cell death in the nematode C. elegans. Cell. 44:1986;817-829
-
(1986)
Cell
, vol.44
, pp. 817-829
-
-
Ellis, H.M.1
Horvitz, H.R.2
-
8
-
-
0027525104
-
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
-
Yuan J., Shaham S., Ledoux S., Ellis H.M., Horvitz H.R. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell. 75:1993;641-652
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
Ellis, H.M.4
Horvitz, H.R.5
-
9
-
-
0842281645
-
Cell death: Critical control points
-
Danial N.N., Korsmeyer S.J. Cell death: critical control points. Cell. 116:2004;205-219
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
10
-
-
0038021272
-
Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more
-
Marsden V.S., Strasser A. Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more. Annu Rev Immunol. 21:2003;71-105
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 71-105
-
-
Marsden, V.S.1
Strasser, A.2
-
11
-
-
0037089068
-
BH3-only proteins - Evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death
-
Bouillet P., Strasser A. BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. J Cell Sci. 115:2002;1567-1574
-
(2002)
J Cell Sci
, vol.115
, pp. 1567-1574
-
-
Bouillet, P.1
Strasser, A.2
-
12
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen G.M. Caspases: the executioners of apoptosis. Biochem J. 326:1997;1-16
-
(1997)
Biochem J
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
13
-
-
0032785021
-
Caspase structure, proteolytic substrates, and function during apoptotic cell death
-
Nicholson D.W. Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ. 6:1999;1028-1042
-
(1999)
Cell Death Differ
, vol.6
, pp. 1028-1042
-
-
Nicholson, D.W.1
-
14
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright K.M., Renatus M., Scott F.L., Sperandio S., Shin H., Pedersen I.M., et al. A unified model for apical caspase activation. Mol Cell. 2:2003;529-541
-
(2003)
Mol Cell
, vol.2
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
-
15
-
-
0035909889
-
Structural basis for the activation of human procaspase-7
-
Riedl S.J., Fuentes-Prior P., Renatus M., Kairies N., Krapp S., Huber R., et al. Structural basis for the activation of human procaspase-7. Proc Natl Acad Sci USA. 98:2001;14790-14795
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14790-14795
-
-
Riedl, S.J.1
Fuentes-Prior, P.2
Renatus, M.3
Kairies, N.4
Krapp, S.5
Huber, R.6
-
16
-
-
0142242170
-
Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway
-
Schweizer A., Briand C., Grutter M.G. Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway. J Biol Chem. 278:2003;42441-42447
-
(2003)
J Biol Chem
, vol.278
, pp. 42441-42447
-
-
Schweizer, A.1
Briand, C.2
Grutter, M.G.3
-
18
-
-
0033605722
-
Caspase-9 can be activated without proteolytic processing
-
Stennicke H.R., Deveraux Q.L., Humke E.W., Reed J.C., Dixit V.M., Salvesen G.S. Caspase-9 can be activated without proteolytic processing. J Biol Chem. 274:1999;8359-8362
-
(1999)
J Biol Chem
, vol.274
, pp. 8359-8362
-
-
Stennicke, H.R.1
Deveraux, Q.L.2
Humke, E.W.3
Reed, J.C.4
Dixit, V.M.5
Salvesen, G.S.6
-
19
-
-
0036205587
-
Mechanisms of caspase activation and inhibition during apoptosis
-
Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol Cell. 9:2002;459-470
-
(2002)
Mol Cell
, vol.9
, pp. 459-470
-
-
Shi, Y.1
-
20
-
-
0030892234
-
Apoptosis by death factor
-
Nagata S. Apoptosis by death factor. Cell. 88:1997;355-365
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
21
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi A., Dixit V.M. Death receptors: signaling and modulation. Science. 281:1998;1305-1308
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
22
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen G., Goeddel D.V. TNF-R1 signaling: a beautiful pathway. Science. 296:2002;1634-1635
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
23
-
-
15144345497
-
Pro-caspase-3 is a major physiologic target of caspase-8
-
Stennicke H.R., Jurgensmeier J.M., Shin H., Deveraux Q., Wolf B.B., Yang X., et al. Pro-caspase-3 is a major physiologic target of caspase-8. J Biol Chem. 273:1998;27084-27090
-
(1998)
J Biol Chem
, vol.273
, pp. 27084-27090
-
-
Stennicke, H.R.1
Jurgensmeier, J.M.2
Shin, H.3
Deveraux, Q.4
Wolf, B.B.5
Yang, X.6
-
24
-
-
0033570104
-
Caspase 8: Igniting the death machine
-
Salvesen G.S. Caspase 8: igniting the death machine. Struct Fold Des. 7:1999;225-229
-
(1999)
Struct Fold des
, vol.7
, pp. 225-229
-
-
Salvesen, G.S.1
-
25
-
-
0032753867
-
Requirement of cooperative functions of two repeated death effector domains in caspase-8 and in MC159 for induction and inhibition of apoptosis, respectively
-
Tsukumo S.I., Yonehara S. Requirement of cooperative functions of two repeated death effector domains in caspase-8 and in MC159 for induction and inhibition of apoptosis, respectively. Gene Cell. 4:1999;541-549
-
(1999)
Gene Cell
, vol.4
, pp. 541-549
-
-
Tsukumo, S.I.1
Yonehara, S.2
-
26
-
-
0032579490
-
An induced proximity model for caspase-8 activation
-
Muzio M., Stockwell B.R., Stennicke H.R., Salvesen G.S., Dixit V.M. An induced proximity model for caspase-8 activation. J Biol Chem. 273:1998;2926-2930
-
(1998)
J Biol Chem
, vol.273
, pp. 2926-2930
-
-
Muzio, M.1
Stockwell, B.R.2
Stennicke, H.R.3
Salvesen, G.S.4
Dixit, V.M.5
-
27
-
-
0042466637
-
Interdimer processing mechanism of procaspase-8 activation
-
Chang D.W., Xing Z., Capacio V.L., Peter M.E., Yang X. Interdimer processing mechanism of procaspase-8 activation. EMBO J. 22:2003;4132-4142
-
(2003)
EMBO J
, vol.22
, pp. 4132-4142
-
-
Chang, D.W.1
Xing, Z.2
Capacio, V.L.3
Peter, M.E.4
Yang, X.5
-
28
-
-
0032485854
-
Multiple conformations of physiological membrane-bound cytochrome c
-
Cortese J.D., Voglino A.L., Hackenbrock C.R. Multiple conformations of physiological membrane-bound cytochrome c. Biochemistry. 37:1998;6402-6409
-
(1998)
Biochemistry
, vol.37
, pp. 6402-6409
-
-
Cortese, J.D.1
Voglino, A.L.2
Hackenbrock, C.R.3
-
29
-
-
0037022352
-
Cytochrome c release from mitochondria proceeds by a two-step process
-
Ott M., Robertson J.D., Gogvadze V., Zhivotovsky B., Orrenius S. Cytochrome c release from mitochondria proceeds by a two-step process. Proc Natl Acad Sci USA. 99:2002;1259-1263
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1259-1263
-
-
Ott, M.1
Robertson, J.D.2
Gogvadze, V.3
Zhivotovsky, B.4
Orrenius, S.5
-
31
-
-
0033386851
-
Mitochondrial membrane permeabilization during the apoptotic process
-
Jacotot E., Costantini P., Laboureau E., Zamzami N., Susin S.A., Kroemer G. Mitochondrial membrane permeabilization during the apoptotic process. Ann NY Acad Sci. 887:1999;18-30
-
(1999)
Ann NY Acad Sci
, vol.887
, pp. 18-30
-
-
Jacotot, E.1
Costantini, P.2
Laboureau, E.3
Zamzami, N.4
Susin, S.A.5
Kroemer, G.6
-
32
-
-
0034786019
-
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
-
Cheng E.H., Wei M.C., Weiler S., Flavell R.A., Mak T.W., Lindsten T., et al. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol Cell. 8:2001;705-711
-
(2001)
Mol Cell
, vol.8
, pp. 705-711
-
-
Cheng, E.H.1
Wei, M.C.2
Weiler, S.3
Flavell, R.A.4
Mak, T.W.5
Lindsten, T.6
-
33
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei M.C., Zong W.X., Cheng E.H., Lindsten T., Panoutsakopoulou V., Ross A.J., et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science. 292:2001;727-730
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
-
34
-
-
0033230611
-
Apoptotic cytosol facilitates Bax translocation to mitochondria that involves cytosolic factor regulated by Bcl-2
-
Nomura M., Shimizu S., Ito T., Narita M., Matsuda H., Tsujimoto Y. Apoptotic cytosol facilitates Bax translocation to mitochondria that involves cytosolic factor regulated by Bcl-2. Cancer Res. 59:1999;5542-5548
-
(1999)
Cancer Res
, vol.59
, pp. 5542-5548
-
-
Nomura, M.1
Shimizu, S.2
Ito, T.3
Narita, M.4
Matsuda, H.5
Tsujimoto, Y.6
-
35
-
-
0033713002
-
Structure of Bax: Coregulation of dimer formation and intracellular localization
-
Suzuki M., Youle R.J., Tjandra N. Structure of Bax: coregulation of dimer formation and intracellular localization. Cell. 103:2000;645-654
-
(2000)
Cell
, vol.103
, pp. 645-654
-
-
Suzuki, M.1
Youle, R.J.2
Tjandra, N.3
-
36
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou H., Henzel W.J., Liu X., Lutschg A., Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell. 90:1997;405-413
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
37
-
-
0035474227
-
The NOD: A signaling module that regulates apoptosis and host defense against pathogens
-
Inohara N., Nunez G. The NOD: a signaling module that regulates apoptosis and host defense against pathogens. Oncogene. 20:2001;6473-6481
-
(2001)
Oncogene
, vol.20
, pp. 6473-6481
-
-
Inohara, N.1
Nunez, G.2
-
38
-
-
0038624558
-
NODs: Intracellular proteins involved in inflammation and apoptosis
-
Inohara N., Nunez G. NODs: intracellular proteins involved in inflammation and apoptosis. Nat Rev Immunol. 3:2003;371-382
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 371-382
-
-
Inohara, N.1
Nunez, G.2
-
39
-
-
0032509354
-
WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation
-
Hu Y., Ding L., Spencer D.M., Nunez G. WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation. J Biol Chem. 273:1998;33489-33494
-
(1998)
J Biol Chem
, vol.273
, pp. 33489-33494
-
-
Hu, Y.1
Ding, L.2
Spencer, D.M.3
Nunez, G.4
-
40
-
-
0344348821
-
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
-
Hu Y., Benedict M.A., Ding L., Nunez G. Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis. EMBO J. 18:1999;3586-3595
-
(1999)
EMBO J
, vol.18
, pp. 3586-3595
-
-
Hu, Y.1
Benedict, M.A.2
Ding, L.3
Nunez, G.4
-
41
-
-
0034105784
-
Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes
-
Cain K., Bratton S.B., Langlais C., Walker G., Brown D.G., Sun X.M., et al. Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes. J Biol Chem. 275:2000;6067-6070
-
(2000)
J Biol Chem
, vol.275
, pp. 6067-6070
-
-
Cain, K.1
Bratton, S.B.2
Langlais, C.3
Walker, G.4
Brown, D.G.5
Sun, X.M.6
-
42
-
-
0034710942
-
Cytochrome c binding to Apaf-1: The effects of dATP and ionic strength
-
Purring-Koch C., McLendon G. Cytochrome c binding to Apaf-1: the effects of dATP and ionic strength. Proc Natl Acad Sci USA. 97:2000;11928-11931
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11928-11931
-
-
Purring-Koch, C.1
McLendon, G.2
-
43
-
-
2442540299
-
Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex
-
Twiddy D., Brown D.G., Adrain C., Jukes R., Martin S.J., Cohen G.M., et al. Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex. J Biol Chem. 279:2004;19665-19682
-
(2004)
J Biol Chem
, vol.279
, pp. 19665-19682
-
-
Twiddy, D.1
Brown, D.G.2
Adrain, C.3
Jukes, R.4
Martin, S.J.5
Cohen, G.M.6
-
44
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu X., Kim C.N., Yang J., Jemmerson R., Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell. 86:1996;147-157
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
45
-
-
0033596980
-
An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
Zou H., Li Y., Liu X., Wang X. An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem. 274:1999;11549-11556
-
(1999)
J Biol Chem
, vol.274
, pp. 11549-11556
-
-
Zou, H.1
Li, Y.2
Liu, X.3
Wang, X.4
-
46
-
-
0036478928
-
The Apaf-1 apoptosome: A large caspase-activating complex
-
Cain K., Bratton S.B., Cohen G.M. The Apaf-1 apoptosome: a large caspase-activating complex. Biochimie. 84:2002;203-214
-
(2002)
Biochimie
, vol.84
, pp. 203-214
-
-
Cain, K.1
Bratton, S.B.2
Cohen, G.M.3
-
47
-
-
0034613302
-
Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1
-
Jiang X., Wang X. Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1. J Biol Chem. 275:2000;31199-31203
-
(2000)
J Biol Chem
, vol.275
, pp. 31199-31203
-
-
Jiang, X.1
Wang, X.2
-
49
-
-
0033573020
-
Caspase-9 and APAF-1 form an active holoenzyme
-
Rodriguez J., Lazebnik Y. Caspase-9 and APAF-1 form an active holoenzyme. Gene Dev. 13:1999;3179-3184
-
(1999)
Gene Dev
, vol.13
, pp. 3179-3184
-
-
Rodriguez, J.1
Lazebnik, Y.2
-
50
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
-
Acehan D., Jiang X., Morgan D.G., Heuser J.E., Wang X., Akey C.W. Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Mol Cell. 9:2002;423-432
-
(2002)
Mol Cell
, vol.9
, pp. 423-432
-
-
Acehan, D.1
Jiang, X.2
Morgan, D.G.3
Heuser, J.E.4
Wang, X.5
Akey, C.W.6
-
51
-
-
0033580926
-
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
-
Saleh A., Srinivasula S.M., Acharya S., Fishel R., Alnemri E.S. Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J Biol Chem. 274:1999;17941-17945
-
(1999)
J Biol Chem
, vol.274
, pp. 17941-17945
-
-
Saleh, A.1
Srinivasula, S.M.2
Acharya, S.3
Fishel, R.4
Alnemri, E.S.5
-
52
-
-
0033635266
-
Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1
-
Chau B.N., Cheng E.H., Kerr D.A., Hardwick J.M. Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1. Mol Cell. 6:2000;31-40
-
(2000)
Mol Cell
, vol.6
, pp. 31-40
-
-
Chau, B.N.1
Cheng, E.H.2
Kerr, D.A.3
Hardwick, J.M.4
-
53
-
-
0035937797
-
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis
-
Chu Z.L., Pio F., Xie Z., Welsh K., Krajewska M., Krajewski S., et al. A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis. J Biol Chem. 276:2001;9239-9245
-
(2001)
J Biol Chem
, vol.276
, pp. 9239-9245
-
-
Chu, Z.L.1
Pio, F.2
Xie, Z.3
Welsh, K.4
Krajewska, M.5
Krajewski, S.6
-
54
-
-
0034253474
-
Negative regulation of the Apaf-1 apoptosome by Hsp70
-
Saleh A., Srinivasula S.M., Balkir L., Robbins P.D., Alnemri E.S. Negative regulation of the Apaf-1 apoptosome by Hsp70. Nat Cell Biol. 2:2000;476-483
-
(2000)
Nat Cell Biol
, vol.2
, pp. 476-483
-
-
Saleh, A.1
Srinivasula, S.M.2
Balkir, L.3
Robbins, P.D.4
Alnemri, E.S.5
-
55
-
-
0034664030
-
Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90
-
Pandey P., Saleh A., Nakazawa A., Kumar S., Srinivasula S.M., Kumar V., et al. Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90. EMBO J. 19:2000;4310-4322
-
(2000)
EMBO J
, vol.19
, pp. 4310-4322
-
-
Pandey, P.1
Saleh, A.2
Nakazawa, A.3
Kumar, S.4
Srinivasula, S.M.5
Kumar, V.6
-
56
-
-
0037428217
-
Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway
-
Jiang X., Kim H.E., Shu H., Zhao Y., Zhang H., Kofron J., et al. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science. 299:2003;223-226
-
(2003)
Science
, vol.299
, pp. 223-226
-
-
Jiang, X.1
Kim, H.E.2
Shu, H.3
Zhao, Y.4
Zhang, H.5
Kofron, J.6
-
57
-
-
0036088471
-
IAP proteins: Blocking the road to death's door
-
Salvesen G.S., Duckett C.S. IAP proteins: blocking the road to death's door. Nat Rev Mol Cell Biol. 3:2002;401-410
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 401-410
-
-
Salvesen, G.S.1
Duckett, C.S.2
-
58
-
-
0033082995
-
IAP family proteins - Suppressors of apoptosis
-
Deveraux Q.L., Reed J.C. IAP family proteins - suppressors of apoptosis. Gene Dev. 13:1999;239-252
-
(1999)
Gene Dev
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
59
-
-
0035831019
-
Structural basis for the inhibition of caspase-3 by XIAP
-
Riedl S.J., Renatus M., Schwarzenbacher R., Zhou Q., Sun C., Fesik S.W., et al. Structural basis for the inhibition of caspase-3 by XIAP. Cell. 104:2001;791-800
-
(2001)
Cell
, vol.104
, pp. 791-800
-
-
Riedl, S.J.1
Renatus, M.2
Schwarzenbacher, R.3
Zhou, Q.4
Sun, C.5
Fesik, S.W.6
-
60
-
-
0035831021
-
Structural basis of caspase-7 inhibition by XIAP
-
Chai J., Shiozaki E., Srinivasula S.M., Wu Q., Datta P., Alnemri E.S., et al. Structural basis of caspase-7 inhibition by XIAP. Cell. 104:2001;769-780
-
(2001)
Cell
, vol.104
, pp. 769-780
-
-
Chai, J.1
Shiozaki, E.2
Srinivasula, S.M.3
Wu, Q.4
Datta, P.5
Alnemri, E.S.6
-
61
-
-
0037291737
-
Mechanism of XIAP-mediated inhibition of caspase-9
-
Shiozaki E.N., Chai J., Rigotti D.J., Riedl S.J., Li P., Srinivasula S.M., et al. Mechanism of XIAP-mediated inhibition of caspase-9. Mol Cell. 11:2003;519-527
-
(2003)
Mol Cell
, vol.11
, pp. 519-527
-
-
Shiozaki, E.N.1
Chai, J.2
Rigotti, D.J.3
Riedl, S.J.4
Li, P.5
Srinivasula, S.M.6
-
62
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C., Fang M., Li Y., Li L., Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell. 102:2000;33-42
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
63
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen A.M., Ekert P.G., Pakusch M., Silke J., Connolly L.M., Reid G.E., et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell. 102:2000;43-53
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
-
64
-
-
0034700491
-
Structural basis of IAP recognition by Smac/DIABLO
-
Wu G., Chai J., Suber T.L., Wu J.W., Du C., Wang X., et al. Structural basis of IAP recognition by Smac/DIABLO. Nature. 408:2000;1008-1012
-
(2000)
Nature
, vol.408
, pp. 1008-1012
-
-
Wu, G.1
Chai, J.2
Suber, T.L.3
Wu, J.W.4
Du, C.5
Wang, X.6
-
65
-
-
0034700495
-
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
-
Liu Z., Sun C., Olejniczak E.T., Meadows R.P., Betz S.F., Oost T., et al. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature. 408:2000;1004-1008
-
(2000)
Nature
, vol.408
, pp. 1004-1008
-
-
Liu, Z.1
Sun, C.2
Olejniczak, E.T.3
Meadows, R.P.4
Betz, S.F.5
Oost, T.6
-
66
-
-
0037028646
-
Apoptotic pathway activation from mitochondria and death receptors without caspase-3 cleavage in failing human myocardium: Fragile balance of myocyte survival?
-
Scheubel R.J., Bartling B., Simm A., Silber R.E., Drogaris K., Darmer D., et al. Apoptotic pathway activation from mitochondria and death receptors without caspase-3 cleavage in failing human myocardium: fragile balance of myocyte survival? J Am Coll Cardiol. 39:2002;481-488
-
(2002)
J Am Coll Cardiol
, vol.39
, pp. 481-488
-
-
Scheubel, R.J.1
Bartling, B.2
Simm, A.3
Silber, R.E.4
Drogaris, K.5
Darmer, D.6
-
67
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida H., Kong Y.Y., Yoshida R., Elia A.J., Hakem A., Hakem R., et al. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell. 94:1998;739-750
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
Elia, A.J.4
Hakem, A.5
Hakem, R.6
-
68
-
-
0032544449
-
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development
-
Cecconi F., Alvarez-Bolado G., Meyer B.I., Roth K.A., Gruss P. Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell. 94:1998;727-737
-
(1998)
Cell
, vol.94
, pp. 727-737
-
-
Cecconi, F.1
Alvarez-Bolado, G.2
Meyer, B.I.3
Roth, K.A.4
Gruss, P.5
-
69
-
-
0037057629
-
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
-
Marsden V.S., O'Connor L., O'Reilly L.A., Silke J., Metcalf D., Ekert P.G., et al. Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature. 419:2002;634-637
-
(2002)
Nature
, vol.419
, pp. 634-637
-
-
Marsden, V.S.1
O'Connor, L.2
O'Reilly, L.A.3
Silke, J.4
Metcalf, D.5
Ekert, P.G.6
-
70
-
-
0033635733
-
BH3-only proteins-essential initiators of apoptotic cell death
-
Huang D.C., Strasser A. BH3-only proteins-essential initiators of apoptotic cell death. Cell. 103:2000;839-842
-
(2000)
Cell
, vol.103
, pp. 839-842
-
-
Huang, D.C.1
Strasser, A.2
-
71
-
-
0034785591
-
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
Suzuki Y., Imai Y., Nakayama H., Takahashi K., Takio K., Takahashi R. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell. 8:2001;613-621
-
(2001)
Mol Cell
, vol.8
, pp. 613-621
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
Takahashi, K.4
Takio, K.5
Takahashi, R.6
-
72
-
-
0037318902
-
Mitochondria, AIF and caspases - Rivaling for cell death execution
-
Penninger J.M., Kroemer G. Mitochondria, AIF and caspases - rivaling for cell death execution. Nat Cell Biol. 5:2003;97-99
-
(2003)
Nat Cell Biol
, vol.5
, pp. 97-99
-
-
Penninger, J.M.1
Kroemer, G.2
-
73
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
Li L.Y., Luo X., Wang X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature. 412:2001;95-99
-
(2001)
Nature
, vol.412
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
74
-
-
0030780106
-
Movement of Bax from the cytosol to mitochondria during apoptosis
-
Wolter K.G., Hsu Y.T., Smith C.L., Nechushtan A., Xi X.G., Youle R.J. Movement of Bax from the cytosol to mitochondria during apoptosis. J Cell Biol. 139:1997;1281-1292
-
(1997)
J Cell Biol
, vol.139
, pp. 1281-1292
-
-
Wolter, K.G.1
Hsu, Y.T.2
Smith, C.L.3
Nechushtan, A.4
G X. Xi5
Youle, R.J.6
-
75
-
-
5244224827
-
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
-
Muchmore S.W., Sattler M., Liang H., Meadows R.P., Harlan J.E., Yoon H.S., et al. X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature. 381:1996;335-341
-
(1996)
Nature
, vol.381
, pp. 335-341
-
-
Muchmore, S.W.1
Sattler, M.2
Liang, H.3
Meadows, R.P.4
Harlan, J.E.5
Yoon, H.S.6
-
76
-
-
0036850312
-
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
-
Kuwana T., Mackey M.R., Perkins G., Ellisman M.H., Latterich M., Schneiter R., et al. Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell. 111:2002;331-342
-
(2002)
Cell
, vol.111
, pp. 331-342
-
-
Kuwana, T.1
MacKey, M.R.2
Perkins, G.3
Ellisman, M.H.4
Latterich, M.5
Schneiter, R.6
-
77
-
-
1542465184
-
Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis
-
Yethon J.A., Epand R.F., Leber B., Epand R.M., Andrews D.W. Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis. J Biol Chem. 278:2003;48935-48941
-
(2003)
J Biol Chem
, vol.278
, pp. 48935-48941
-
-
Yethon, J.A.1
Epand, R.F.2
Leber, B.3
Epand, R.M.4
Andrews, D.W.5
-
78
-
-
0032422488
-
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
-
Narita M., Shimizu S., Ito T., Chittenden T., Lutz R.J., Matsuda H., et al. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc Natl Acad Sci USA. 95:1998;14681-14686
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14681-14686
-
-
Narita, M.1
Shimizu, S.2
Ito, T.3
Chittenden, T.4
Lutz, R.J.5
Matsuda, H.6
-
79
-
-
0036463405
-
A matter of life and death
-
Green D.R., Evan G.I. A matter of life and death. Cancer Cell. 1:2002;19-30
-
(2002)
Cancer Cell
, vol.1
, pp. 19-30
-
-
Green, D.R.1
Evan, G.I.2
-
80
-
-
0035823579
-
Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation
-
Rao R.V., Hermel E., Castro-Obregon S., del Rio G., Ellerby L.M., Ellerby H.M., et al. Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation. J Biol Chem. 276:2001;33869-33874
-
(2001)
J Biol Chem
, vol.276
, pp. 33869-33874
-
-
Rao, R.V.1
Hermel, E.2
Castro-Obregon, S.3
Del Rio, G.4
Ellerby, L.M.5
Ellerby, H.M.6
-
82
-
-
0037810844
-
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
-
Zong W.X., Li C., Hatzivassiliou G., Lindsten T., Yu Q.C., Yuan J., et al. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis. J Cell Biol. 162:2003;59-69
-
(2003)
J Cell Biol
, vol.162
, pp. 59-69
-
-
Zong, W.X.1
Li, C.2
Hatzivassiliou, G.3
Lindsten, T.4
Yu, Q.C.5
Yuan, J.6
-
83
-
-
0034698878
-
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
-
Nakagawa T., Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol. 150:2000;887-894
-
(2000)
J Cell Biol
, vol.150
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
84
-
-
0037077254
-
Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway
-
Rao R.V., Castro-Obregon S., Frankowski H., Schuler M., Stoka V., del Rio G., et al. Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway. J Biol Chem. 277:2002;21836-21842
-
(2002)
J Biol Chem
, vol.277
, pp. 21836-21842
-
-
Rao, R.V.1
Castro-Obregon, S.2
Frankowski, H.3
Schuler, M.4
Stoka, V.5
Del Rio, G.6
-
85
-
-
0037072937
-
An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12
-
Morishima N., Nakanishi K., Takenouchi H., Shibata T., Yasuhiko Y. An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem. 277:2002;34287-34294
-
(2002)
J Biol Chem
, vol.277
, pp. 34287-34294
-
-
Morishima, N.1
Nakanishi, K.2
Takenouchi, H.3
Shibata, T.4
Yasuhiko, Y.5
-
86
-
-
0346250162
-
Regulation of apoptosis by endoplasmic reticulum pathways
-
Breckenridge D.G., Germain M., Mathai J.P., Nguyen M., Shore G.C. Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene. 22:2003;8608-8618
-
(2003)
Oncogene
, vol.22
, pp. 8608-8618
-
-
Breckenridge, D.G.1
Germain, M.2
Mathai, J.P.3
Nguyen, M.4
Shore, G.C.5
-
87
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature. 403:2000;98-103
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
-
89
-
-
0036156875
-
Losing heart: The role of apoptosis in heart disease - A novel therapeutic target?
-
Gill C., Mestril R., Samali A. Losing heart: the role of apoptosis in heart disease - a novel therapeutic target? FASEB J. 16:2002;135-146
-
(2002)
FASEB J
, vol.16
, pp. 135-146
-
-
Gill, C.1
Mestril, R.2
Samali, A.3
-
90
-
-
0036836660
-
Pathophysiologic role of myocardial apoptosis in post-infarction left ventricular remodeling
-
Abbate A., Biondi-Zoccai G.G., Baldi A. Pathophysiologic role of myocardial apoptosis in post-infarction left ventricular remodeling. J Cell Physiol. 193:2002;145-153
-
(2002)
J Cell Physiol
, vol.193
, pp. 145-153
-
-
Abbate, A.1
Biondi-Zoccai, G.G.2
Baldi, A.3
-
92
-
-
0036242344
-
New insights into the role of apoptosis in cardiovascular disease
-
Kang P.M., Yue P., Izumo S. New insights into the role of apoptosis in cardiovascular disease. Circ J. 66:2002;1-9
-
(2002)
Circ J
, vol.66
, pp. 1-9
-
-
Kang, P.M.1
Yue, P.2
Izumo, S.3
-
93
-
-
0037464448
-
Mitochondria in apoptosis of ischemic heart
-
Borutaite V., Brown G.C. Mitochondria in apoptosis of ischemic heart. FEBS Lett. 541:2003;1-5
-
(2003)
FEBS Lett
, vol.541
, pp. 1-5
-
-
Borutaite, V.1
Brown, G.C.2
-
94
-
-
0037357698
-
Regulation of cardiac myocyte cell death
-
Clerk A., Cole S.M., Cullingford T.E., Harrison J.G., Jormakka M., Valks D.M. Regulation of cardiac myocyte cell death. Pharmacol Ther. 97:2003;223-261
-
(2003)
Pharmacol Ther
, vol.97
, pp. 223-261
-
-
Clerk, A.1
Cole, S.M.2
Cullingford, T.E.3
Harrison, J.G.4
Jormakka, M.5
Valks, D.M.6
-
95
-
-
10744229047
-
Intracellular ATP is required for mitochondrial apoptotic pathways in isolated hypoxic rat cardiac myocytes
-
Tatsumi T., Shiraishi J., Keira N., Akashi K., Mano A., Yamanaka S., et al. Intracellular ATP is required for mitochondrial apoptotic pathways in isolated hypoxic rat cardiac myocytes. Cardiovasc Res. 59:2003;428-440
-
(2003)
Cardiovasc Res
, vol.59
, pp. 428-440
-
-
Tatsumi, T.1
Shiraishi, J.2
Keira, N.3
Akashi, K.4
Mano, A.5
Yamanaka, S.6
-
96
-
-
0031023852
-
Apoptosis in human acute myocardial infarction
-
Saraste A., Pulkki K., Kallajoki M., Henriksen K., Parvinen M., Voipio-Pulkki L.M. Apoptosis in human acute myocardial infarction. Circulation. 95:1997;320-323
-
(1997)
Circulation
, vol.95
, pp. 320-323
-
-
Saraste, A.1
Pulkki, K.2
Kallajoki, M.3
Henriksen, K.4
Parvinen, M.5
Voipio-Pulkki, L.M.6
-
97
-
-
0033839388
-
Apoptosis is initiated by myocardial ischemia and executed during reperfusion
-
Freude B., Masters T.N., Robicsek F., Fokin A., Kostin S., Zimmermann R., et al. Apoptosis is initiated by myocardial ischemia and executed during reperfusion. J Mol Cell Cardiol. 32:2000;197-208
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 197-208
-
-
Freude, B.1
Masters, T.N.2
Robicsek, F.3
Fokin, A.4
Kostin, S.5
Zimmermann, R.6
-
98
-
-
0034698118
-
Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation
-
Kang P.M., Haunstetter A., Aoki H., Usheva A., Izumo S. Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation. Circ Res. 87:2000;118-125
-
(2000)
Circ Res
, vol.87
, pp. 118-125
-
-
Kang, P.M.1
Haunstetter, A.2
Aoki, H.3
Usheva, A.4
Izumo, S.5
-
99
-
-
0033535974
-
Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis
-
von Harsdorf R., Li P.F., Dietz R. Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation. 99:1999;2934-2941
-
(1999)
Circulation
, vol.99
, pp. 2934-2941
-
-
Von Harsdorf, R.1
Li, P.F.2
Dietz, R.3
-
100
-
-
0032570292
-
Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor
-
Yaoita H., Ogawa K., Maehara K., Maruyama Y. Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor. Circulation. 97:1998;276-281
-
(1998)
Circulation
, vol.97
, pp. 276-281
-
-
Yaoita, H.1
Ogawa, K.2
Maehara, K.3
Maruyama, Y.4
-
101
-
-
0035684308
-
Blocking caspase-activated apoptosis improves contractility in failing myocardium
-
Laugwitz K.L., Moretti A., Weig H.J., Gillitzer A., Pinkernell K., Ott T., et al. Blocking caspase-activated apoptosis improves contractility in failing myocardium. Hum Gene Ther. 12:2001;2051-2063
-
(2001)
Hum Gene Ther
, vol.12
, pp. 2051-2063
-
-
Laugwitz, K.L.1
Moretti, A.2
Weig, H.J.3
Gillitzer, A.4
Pinkernell, K.5
Ott, T.6
-
102
-
-
0034064429
-
Apoptosis in heart failure: Is there light at the end of the tunnel (TUNEL)?
-
Kang P.M., Izumo S. Apoptosis in heart failure: is there light at the end of the tunnel (TUNEL)? J Card Fail. 6:2000;43-46
-
(2000)
J Card Fail
, vol.6
, pp. 43-46
-
-
Kang, P.M.1
Izumo, S.2
-
103
-
-
85047694494
-
A mechanistic role for cardiac myocyte apoptosis in heart failure
-
Wencker D., Chandra M., Nguyen K., Miao W., Garantziotis S., Factor S.M., et al. A mechanistic role for cardiac myocyte apoptosis in heart failure. J Clin Invest. 111:2003;1497-1504
-
(2003)
J Clin Invest
, vol.111
, pp. 1497-1504
-
-
Wencker, D.1
Chandra, M.2
Nguyen, K.3
Miao, W.4
Garantziotis, S.5
Factor, S.M.6
-
104
-
-
0032211138
-
The Fas/Fas ligand system is involved in the pathogenesis of autoimmune myocarditis in rats
-
Ishiyama S., Hiroe M., Nishikawa T., Shimojo T., Abe S., Fujisaki H., et al. The Fas/Fas ligand system is involved in the pathogenesis of autoimmune myocarditis in rats. J Immunol. 161:1998;4695-4701
-
(1998)
J Immunol
, vol.161
, pp. 4695-4701
-
-
Ishiyama, S.1
Hiroe, M.2
Nishikawa, T.3
Shimojo, T.4
Abe, S.5
Fujisaki, H.6
-
105
-
-
0037304773
-
Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo
-
Lee P., Sata M., Lefer D.J., Factor S.M., Walsh K., Kitsis R.N. Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo. Am J Physiol Heart Circ Physiol. 284:2003;456-463
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
, pp. 456-463
-
-
Lee, P.1
Sata, M.2
Lefer, D.J.3
Factor, S.M.4
Walsh, K.5
Kitsis, R.N.6
-
106
-
-
0030763808
-
Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha
-
Kubota T., McTiernan C.F., Frye C.S., Slawson S.E., Lemster B.H., Koretsky A.P., et al. Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha. Circ Res. 81:1997;627-635
-
(1997)
Circ Res
, vol.81
, pp. 627-635
-
-
Kubota, T.1
McTiernan, C.F.2
Frye, C.S.3
Slawson, S.E.4
Lemster, B.H.5
Koretsky, A.P.6
-
107
-
-
0041736398
-
Cardiomyocyte death in patients with end-stage heart failure before and after support with a left ventricular assist device: Low incidence of apoptosis despite ubiquitous mediators
-
de Jonge N., van Wichen D.F., van Kuik J., Kirkels H., Lahpor J.R., Gmelig-Meyling F.H., et al. Cardiomyocyte death in patients with end-stage heart failure before and after support with a left ventricular assist device: low incidence of apoptosis despite ubiquitous mediators. J Heart Lung Transplant. 22:2003;1028-1036
-
(2003)
J Heart Lung Transplant
, vol.22
, pp. 1028-1036
-
-
De Jonge, N.1
Van Wichen, D.F.2
Van Kuik, J.3
Kirkels, H.4
Lahpor, J.R.5
Gmelig-Meyling, F.H.6
-
108
-
-
0033781314
-
Cellular FLIP is expressed in cardiomyocytes and down-regulated in TUNEL-positive grafted cardiac tissues
-
Imanishi T., Murry C.E., Reinecke H., Hano T., Nishio I., Liles W.C., et al. Cellular FLIP is expressed in cardiomyocytes and down-regulated in TUNEL-positive grafted cardiac tissues. Cardiovasc Res. 48:2000;101-110
-
(2000)
Cardiovasc Res
, vol.48
, pp. 101-110
-
-
Imanishi, T.1
Murry, C.E.2
Reinecke, H.3
Hano, T.4
Nishio, I.5
Liles, W.C.6
-
109
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler M., Thome M., Hahne M., Schneider P., Hofmann K., Steiner V., et al. Inhibition of death receptor signals by cellular FLIP. Nature. 388:1997;190-195
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
-
110
-
-
0032532013
-
FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation
-
Kataoka T., Schroter M., Hahne M., Schneider P., Irmler M., Thome M., et al. FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation. J Immunol. 161:1998;3936-3942
-
(1998)
J Immunol
, vol.161
, pp. 3936-3942
-
-
Kataoka, T.1
Schroter, M.2
Hahne, M.3
Schneider, P.4
Irmler, M.5
Thome, M.6
-
111
-
-
7144263731
-
FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
-
Yeh W.C., Pompa J.L., McCurrach M.E., Shu H.B., Elia A.J., Shahinian A., et al. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science. 279:1998;1954-1958
-
(1998)
Science
, vol.279
, pp. 1954-1958
-
-
Yeh, W.C.1
Pompa, J.L.2
McCurrach, M.E.3
Shu, H.B.4
Elia, A.J.5
Shahinian, A.6
-
112
-
-
0033520463
-
The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes
-
Bialik S., Cryns V.L., Drincic A., Miyata S., Wollowick A.L., Srinivasan A., et al. The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes. Circ Res. 85:1999;403-414
-
(1999)
Circ Res
, vol.85
, pp. 403-414
-
-
Bialik, S.1
Cryns, V.L.2
Drincic, A.3
Miyata, S.4
Wollowick, A.L.5
Srinivasan, A.6
-
113
-
-
0033617296
-
Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes
-
Malhotra R., Brosius F.C. III. Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes. J Biol Chem. 274:1999;12567-12575
-
(1999)
J Biol Chem
, vol.274
, pp. 12567-12575
-
-
Malhotra, R.1
Brosius III, F.C.2
-
114
-
-
0034698118
-
Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation
-
Kang P.M., Haunstetter A., Aoki H., Usheva A., Izumo S. Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation. Circ Res. 87:2000;118-125
-
(2000)
Circ Res
, vol.87
, pp. 118-125
-
-
Kang, P.M.1
Haunstetter, A.2
Aoki, H.3
Usheva, A.4
Izumo, S.5
-
115
-
-
0033959317
-
Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes
-
de Moissac D., Gurevich R.M., Zheng H., Singal P.K., Kirshenbaum L.A. Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes. J Mol Cell Cardiol. 32:2000;53-63
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 53-63
-
-
De Moissac, D.1
Gurevich, R.M.2
Zheng, H.3
Singal, P.K.4
Kirshenbaum, L.A.5
-
116
-
-
0034698118
-
Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation
-
Kang P.M., Haunstetter A., Aoki H., Usheva A., Izumo S. Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation. Circ Res. 87:2000;118-125
-
(2000)
Circ Res
, vol.87
, pp. 118-125
-
-
Kang, P.M.1
Haunstetter, A.2
Aoki, H.3
Usheva, A.4
Izumo, S.5
-
117
-
-
18644378983
-
Apoptosis and post-infarction left ventricular remodeling
-
Baldi A., Abbate A., Bussani R., Patti G., Melfi R., Angelini A., et al. Apoptosis and post-infarction left ventricular remodeling. J Mol Cell Cardiol. 34:2002;165-174
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 165-174
-
-
Baldi, A.1
Abbate, A.2
Bussani, R.3
Patti, G.4
Melfi, R.5
Angelini, A.6
-
118
-
-
0034016833
-
Caspase inhibition and limitation of myocardial infarct size: Protection against lethal reperfusion injury
-
Mocanu M.M., Baxter G.F., Yellon D.M. Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury. Br J Pharmacol. 130:2000;197-200
-
(2000)
Br J Pharmacol
, vol.130
, pp. 197-200
-
-
Mocanu, M.M.1
Baxter, G.F.2
Yellon, D.M.3
-
119
-
-
4344684550
-
Calpain and caspase-3 inhibitors reduce infarct size and post-ischemic apoptosis in rat heart without modifying contractile recovery
-
Perrin C., Ecarnot-Laubriet A., Vergely C., Rochette L. Calpain and caspase-3 inhibitors reduce infarct size and post-ischemic apoptosis in rat heart without modifying contractile recovery. Cell Mol Biol. 49:2003;497-505
-
(2003)
Cell Mol Biol
, vol.49
, pp. 497-505
-
-
Perrin, C.1
Ecarnot-Laubriet, A.2
Vergely, C.3
Rochette, L.4
-
120
-
-
0010034895
-
Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury
-
Brocheriou V., Hagege A.A., Oubenaissa A., Lambert M., Mallet V.O., Duriez M., et al. Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury. J Gene Med. 2:2000;326-333
-
(2000)
J Gene Med
, vol.2
, pp. 326-333
-
-
Brocheriou, V.1
Hagege, A.A.2
Oubenaissa, A.3
Lambert, M.4
Mallet, V.O.5
Duriez, M.6
-
121
-
-
0033046572
-
Human skeletal muscle cytosols are refractory to cytochrome c-dependent activation of type-II caspases and lack APAF-1
-
Burgess D.H., Svensson M., Dandrea T., Gronlund K., Hammarquist F., Orrenius S., et al. Human skeletal muscle cytosols are refractory to cytochrome c-dependent activation of type-II caspases and lack APAF-1. Cell Death Differ. 6:1999;256-261
-
(1999)
Cell Death Differ
, vol.6
, pp. 256-261
-
-
Burgess, D.H.1
Svensson, M.2
Dandrea, T.3
Gronlund, K.4
Hammarquist, F.5
Orrenius, S.6
-
122
-
-
0032574745
-
ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases
-
Koseki T., Inohara N., Chen S., Nunez G. ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases. Proc Natl Acad Sci USA. 95:1998;5156-5160
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5156-5160
-
-
Koseki, T.1
Inohara, N.2
Chen, S.3
Nunez, G.4
-
123
-
-
0033539994
-
ARC inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heart-derived H9c2 cells
-
Ekhterae D., Lin Z., Lundberg M.S., Crow M.T., Brosius F.C. III, Nunez G. ARC inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heart-derived H9c2 cells. Circ Res. 85:1999;e70-e77
-
(1999)
Circ Res
, vol.85
-
-
Ekhterae, D.1
Lin, Z.2
Lundberg, M.S.3
Crow, M.T.4
Brosius III, F.C.5
Nunez, G.6
-
124
-
-
0035823571
-
The apoptotic regulatory protein ARC (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function
-
Neuss M., Monticone R., Lundberg M.S., Chesley A.T., Fleck E., Crow M.T. The apoptotic regulatory protein ARC (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function. J Biol Chem. 276:2001;33915-33922
-
(2001)
J Biol Chem
, vol.276
, pp. 33915-33922
-
-
Neuss, M.1
Monticone, R.2
Lundberg, M.S.3
Chesley, A.T.4
Fleck, E.5
Crow, M.T.6
-
125
-
-
0036671304
-
Phosphorylation by protein kinase CK2: A signaling switch for the caspase-inhibiting protein ARC
-
Li P.F., Li J., Muller E.C., Otto A., Dietz R., von Harsdorf R. Phosphorylation by protein kinase CK2: a signaling switch for the caspase-inhibiting protein ARC. Mol Cell. 10:2002;247-258
-
(2002)
Mol Cell
, vol.10
, pp. 247-258
-
-
Li, P.F.1
Li, J.2
Muller, E.C.3
Otto, A.4
Dietz, R.5
Von Harsdorf, R.6
-
126
-
-
0037031297
-
TAT protein transduction into isolated perfused hearts: TAT-apoptosis repressor with caspase recruitment domain is cardioprotective
-
Gustafsson A.B., Sayen M.R., Williams S.D., Crow M.T., Gottlieb R.A. TAT protein transduction into isolated perfused hearts: TAT-apoptosis repressor with caspase recruitment domain is cardioprotective. Circulation. 106:2002;735-739
-
(2002)
Circulation
, vol.106
, pp. 735-739
-
-
Gustafsson, A.B.1
Sayen, M.R.2
Williams, S.D.3
Crow, M.T.4
Gottlieb, R.A.5
-
127
-
-
0037973298
-
Blocking the development of postischemic cardiomyopathy with viral gene transfer of the apoptosis repressor with caspase recruitment domain
-
Chatterjee S., Bish L.T., Jayasankar V., Stewart A.S., Woo Y.J., Crow M.T., et al. Blocking the development of postischemic cardiomyopathy with viral gene transfer of the apoptosis repressor with caspase recruitment domain. J Thorac Cardiovasc Surg. 125:2003;1461-1469
-
(2003)
J Thorac Cardiovasc Surg
, vol.125
, pp. 1461-1469
-
-
Chatterjee, S.1
Bish, L.T.2
Jayasankar, V.3
Stewart, A.S.4
Woo, Y.J.5
Crow, M.T.6
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