The Fas/Fas ligand system is involved in the pathogenesis of autoimmune myocarditis in rats

Journal of Immunology

Volumn 161, Issue 9, 1998, Pages 4695-4701

  Ishiyama, Shigeru ^a,b   Hiroe, Michiaki ^a   Nishikawa, Toshio ^b   Shimojo, Takashi ^a   Abe, Shinji ^a   Fujisaki, Hiroyuki ^a   Ito, Hiroshi ^a   Yamakawa, Katsutoshi ^c,d   Kobayashi, Nobuyuki ^c,d   Kasajima, Takeshi ^b   Marumo, Fumiaki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c Department of Internal Medicine   (Japan)

^d NAGASAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; IN SITU HYBRIDIZATION; LYMPHOCYTIC INFILTRATION; MALE; MYOCARDITIS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT;

ACUTE DISEASE; ANIMALS; ANTIGENS, CD95; APOPTOSIS; AUTOIMMUNE DISEASES; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CONVALESCENCE; FAS LIGAND PROTEIN; IMMUNIZATION; IN SITU NICK-END LABELING; MALE; MEMBRANE GLYCOPROTEINS; MYOCARDITIS; MYOCARDIUM; MYOSINS; RATS; RATS, INBRED LEW; RNA, MESSENGER; SWINE;

EID: 0032211138     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Kerr, J. F., A. H. Whllie, and A. R. Currie. 1972. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26:239.
2. Walker, N. I., B. V. Harmon, G. C. Gobe, and J. F. K. Kerr. 1988. Patterns of cell death. Methods Achiev. Exp. Pathol. 13:18.
3. Arends, M. J., R. G. Morris, and A. H. Wyllie. 1990. Apoptosis: the role of the endonuclease. Am. J. Pathol. 136:593.
4. Walker, P. R., C. Smith, T. J. L. Youdale, J. F. Whitfield, and M. Sikorska. 1991. Topoisomerase II-reactive chemotherapeutic drugs induced apoptosis in thymocytes. Cancer Res. 51:1078.
5. Bertrand, R., M. Sarang, J. Jenkin, D. Kerrigan, and Y. Pommier. 1991. Differential induction of secondary DNA fragmentation by topoisomerase II inhibitors in human tumor cell lines with amplified c-myc expression. Cancer Res. 51:6280.
6. Barry, M. A., C. A. Behnke, and A. Eastman. 1990. Activation of programmed cell death (apoptosis) by cisplatin, other anti-cancer drugs, toxins and hyperthermia. Biochem. Pharmacol. 40:2353.
7. Terai, C., R. S. Kornbluth, C. D. Pauza, D. D. Richman, and D. A. Carson. 1991. Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1. J. Clin. Invest. 87:1710.
8. Rao, L., M. Debbas, P. Sabbatini, D. Hockenberry, S. Korsmeyer, and E. White. 1992. The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and bcl-2 proteins. Proc. Natl. Acad. Sci. USA 89:7742.
9. Levine, B., Q. Huang, J. T. Isaacs, J. C. Reed, D. E. Griffin, and J. M. Hardwick. 1993. Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature 361:739.
10. Takano, Y. S., B. V. Harmon, and J. F. R. Kerr. 1991. Apoptosis induced by mild hyperthermia in human and murine tumor cell lines: a study using electron microscopy and DNA gel electrophoresis. J. Pathol. 163:329.
11. Kajstura, J., M. Mansukhani, W. Cheng, K. Reiss, S. Krajewski, J. C. Reed, F. Quaini, E. F. Sonnenblick, and P. Anversa. 1995. Programmed cell death and the expression of the protooncogene Bcl-2 in myocyte during postnatal maturation of the heart. Exp. Cell Res. 219:110.
12. Gottlieb, R. A., K. O. Burleson, R. A. Kloner, B. M. Bablor, and R. L. Engler. 1994. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J. Clin. Invest. 94:1621.
13. Tanaka, M., H. Ito, S. Adachi, H. Akimoto, T. Nishikawa, T. Kasajima, F. Marumo, and M. Hiroe. 1994. Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circ. Res. 75:426.
14. Itoh, G., J. Tamura, M. Suzuki, Y. Suzuki, H. Ikeda, M. Koike, M. Nomura, T. Jie, and K. Ito. 1995. DNA fragmentation of human infarcted myocardial cells demonstrated by the nick end labeling method and DNA agarose gel electrophoresis. Am. J. Pathol. 146:1325.
15. Narula, J. N., N. Haider, R. Virmani, T. G. DiSalvo, F. D. Kolodgie, R. J. Hajjar, U. Schmidt, M. J. Semigran, G. W. Dec, and B.-A. Khaw. 1996. Apoptosis in myocytes in end-stage heart failure. N. Engl. J. Med. 335:1182.
16. Mallat, Z., A. Tedgui, F. Fontaliran, R. Frank, M. Durigon, and G. Fontaine. 1996. Evidence of apoptosis in arrhythmogenic right ventricular dysplasia. N. Engl. J. Med. 335:1190.
17. Ishiyama, S., M. Hiroe, T. Nishikawa, S. Abe, T. Shimojo, H. Ito, S. Ozasa, K. Yamakawa, M. Matsuzaki, M. U. Mohammed, H. Nakazawa, T. Kasajima, and F. Marumo. 1997. Nitric oxide contributes to the progression of myocardial damage in experimental autoimmune myocarditis in rats. Circulation 95:489.
18. Kodama, M., Y. Matsumoto, M. Fujiwara, S. Zhang, H. Hanawa, E. Itoh, T. Tsuda, T. Izumi, and A. Shibata. 1991. Characteristics of giant cells and factors related to the formation of giant cells in myocarditis. Circ. Res. 69:1042.
19. Cheng, J., T. Zhou, C. Liu, J. P. Shapiro, M. J. Brauer, M. C. Kiefer, P. J. Barr, and J. D. Mountz. 1994. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science 263:1759.
20. Russell, J. H., B. Rush, C. Weaver, and R. Wang. 1993. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc. Natl. Acad. Sci. USA 90:4409.
21. Watson, M. L., J. K. Rao, G. S. Gilkeson, P. Ruiz, E. M. Eicher, D. S. Pisetsky, A. Matsuzawa, J. M. Rochelle, and M. F. Seldin. 1992. Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renel disease-modifying loci. J. Exp. Med. 176:1645.
22. Hakuno, N., T. Koji, T. Yano, N. Kobayashi, N. Tsutsumi, O. Y. Taketani, and P. K. Nakane. 1996. Fas/APO-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia. Endocrinology 137:1938.
23. Gavrieli, Y., Y. Sherman, and S.-A. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:493.
24. O'Reilly, M. S., L. Holmgren, C. Chen, and J. Folkman. 1996. Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat. Med. 2:689.
25. Facchinetti, A., M. Tessarollo, R. Mazzocchi, D. C. Kingston, and C. Blasi. 1991. An improved method for the detection of DNA fragmentation. J. Immunol. Methods 136:125.
26. + thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr. Proc. Natl. Acad. Sci. USA 90:10340.
27. Suda, T., T. Takahashi, P. Golstein, and S. Nagata. 1993. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75:1169.
28. Kägi, D., F. Vignaux, B. Ledermann, K. Burki, V. Depraetere, S. Nagata, H. Hengartner, and P. Golstein. 1994. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science 265:528.
29. Hanabuchi, S., M. Koyanagi, A. Kawasaki, N. Shinohara, A. Maisuzawa, Y. Nishimura, Y. Kobayashi, S. Yonehara, H. Yagita, and K. Okumura. 1994. Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity. Proc. Natl. Acad. Sci. USA 91:4930.
30. Oehm, A., I. Behrmann, W. Falk, M. Pawlita, G. Maier, C. Klas, M. Li-Weber, S. Richards, J. Dhein, B. C. Trauth, H. Ponsting, and P. H. Krammer. 1992. Purification and molecular cloning of the APO-1 surface antigen, a member of the TNF/NGF receptor superfamily. J. Biol. Chem. 267:10709.
31. Fujisaki, H., H. Ito, Y. Hirata, M. Tanaka, M. Hata, M. Lin, S. Adachi, H. Akimoto, F. Marumo, and M. Hiroe. 1995. Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression. J. Clin. Invest. 96:1059.
32. Feinberg, A. P., and B. A. Vogelstein. 1983. Technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6.
33. Nagata, S., and P. Golstein. 1995. The Fas death factor. Science 267:1449.
34. Krammer, P. H., J. Dhein, H. Walczak, I. Behrmann, S. Mariani, B. Matiba, M. Fath, P. T. Daniel, E. Knipping, M. O. Westendorp, K. Stricker, C. Baumler, S. Hellbardt, M. Germer, M. E. Peter, and K.-M. Debatin. 1994. The role of APO-1-mediated apoptosis in the immune system. Immunol. Rev. 142:175.
35. Yagita, H., K. Seino, N. Kayagaki, and K. Okumura. 1996. CD95 ligand in graft rejection. Nature 379:682.
36. Trauth, B. C., C. Klas, M. J. Peters, S. Matzku, P. Moller, W. Falk, K. M. Debatin, and P. H. Krammer. 1989. Monoclonal antibody-mediated tumor regression by apoptosis. Science 245:301.
37. Yagita, H., M. Nakata, A. Kawasaki, Y. Shinkai, and K. Okumura. 1992. Role of perform in lymphocyte-mediated cytolysis. Adv. Immunol. 51:215.
38. Kobayashi, N., Y. Hamamoto, N. Yamamoto, A. Ishii, M. Yonehara, and S. Yonehara. 1990. Anti-Fas monoclonal antibody is cytocidal to human immunodeficiency virus-infected cells without augmenting viral replication. Proc. Natl. Acad. Sci. USA 87:9620.
39. Hanabuchi, S., M. Koyanagi, A. Kawasaki, N. Shinohara, A. Matsuzawa, Y. Nishimura, Y. Kobayashi, S. Yonehara, H. Yagita, and K. Okumura. 1994. Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity. Proc. Natl. Acad. Sci. USA 91:4930.
40. Itoh, N., S. Yonehara, A. Ishii, M. Yonehara, S.-I. Mizushima, M. Sameshima, A. Hase, Y. Seto, and S. Nagata. 1991. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233.
41. Ogasawara, J., R. Watanabe-Fukunaga, M. Adachi, A. Matsuzawa, T. Kasugai, Y. Kitamura, N. Itoh, T. Suda, and S. Nagata. 1993. Lethal effect of the anti-Fas antibody in mice. Nature 364:306.
42. Suda, T., S. Takahashi, P. Golstein, and S. Nagata. 1993. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75:1169.
43. Pummerer, C., P. Berger, M. Fruhwirth, C. Ofner, and N. Neu. 1991. Cellular infiltrate, major histocompatibility antigen expression and immunopathogenic mechanisms in cardiac myosin-induced myocarditis. Lab. Invest. 65:538.
44. Dhein, J., H. Walczak, C. Baumler, K.-M. Debatin, and P. H. Krammer. 1995. Autocrine T cell suicide mediated by APO-1 (Fas/CD9S). Nature 373:438.