Requirement of cooperative functions of two repeated death effector domains in caspase-8 and in MC159 for induction and inhibition of apoptosis, respectively

Genes to Cells

Volumn 4, Issue 9, 1999, Pages 541-549

  Tsukumo, Shin Ichi ^a,b   Yonehara, Shin ^a  

^a KYOTO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; FAS ANTIGEN; REGULATOR PROTEIN;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; BINDING AFFINITY; GENE DELETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; TANDEM REPEAT; YEAST;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 8; CASPASE 9; CASPASES; FLUORESCENT ANTIBODY TECHNIQUE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; TANDEM REPEAT SEQUENCES; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 0032753867     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1999.00280.x     Document Type: Article

References (25)

1. Alnemri, E.S. (1997) Mammalian cell death proteases: a family of highly conserved aspartate specific cysteine proteases. J. Cell. Biochem. 64, 33-42.
2. Bertin, J., Armstrong, R.C., Ottilie, S., et al. (1997) Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis. Proc. Natl. Acad. Sci. USA 94, 1172-1176.
3. Boldin, M.P., Goncharov, T.M., Goltsev, Y.V. & Wallach, D. (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85, 803-815.
4. Butt, A.J., Harvey, N.L., Parasivam, G. & Kumar, S. (1998) Dimerization and autoprocessing of the Nedd2 (caspase-2) precursor requires both the prodomain and the carboxyl-terminal regions. J. Biol. Chem. 273, 6763-6768.
5. Chinnaiyan, A.M., O'Rourke, K., Lane, B.R. & Dixit, V.M. (1997) Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science 275, 1122-1126.
6. Chinnaiyan, A.M., O'Rourke, K., Tewari, M. & Dixit, V.M. (1995) FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81, 505-512.
7. Chou, J.J., Matsuo, H., Duan, H. & Wagner, G. (1998) Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment. Cell 94, 171-180.
8. Eberstadt, M., Huang, B., Chen, Z., et al. (1998) NMR structure and mutagenesis of the FADD (Mort1) death-effector domain. Nature 392, 941-945.
9. Eberstadt, M., Huang, B., Olejniczak, E.T. & Fesik, S.W. (1997) The lymphoproliferation mutation in Fas locally unfolds the Fas death domain. Nature Struct. Biol. 4, 983-985.
10. Fernandes-Alnemri, T., Armstrong, R.C., Krebs, J., et al. (1996) In vitro activation of CPP. 32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc. Natl Acad. Sci. USA 93, 7464-7469.
11. Hara, T. & Miyajima, A. (1992) Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3). EMBO J. 11, 1875-1884.
12. Hofmann, K., Bucher, P. & Tschopp, J. (1997) The CARD domain: a new apoptotic signalling motif. Trends. Biochem. Sci. 22, 155-156.
13. Hsu, H., Shu, H.B., Pan, M.G. & Goeddel, D.V. (1996) TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84, 299-308.
14. Imai, Y., Kimura, T., Murakami, A., Yajima, N., Sakamaki, K. & Yonehara, S. (1999) The CED-4-homologous protein FLASH is involved in FAS-mediated activation of caspase-8 during apoptosis. Nature 398, 777-785.
15. Irmler, M., Thome, M., Hahne, M., et al. (1997) Inhibition of death receptor signals by cellular FLIP. Nature 388, 190-195.
16. Muzio, M., Chinnaiyan, A.M., Kischkel, F.C., et al. (1996) FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85, 817-827.
17. Ogawa, H., Inouye, S., Tsuji, F.I., Yasuda, K. & Umesono, K. (1995). Localization, trafficking, and temperature-dependence of the Aequorea green fluorescent protein in cultured vertebrate cells. Proc. Natl. Acad. Sci. USA 92, 11899-11903.
18. Pan, G., Humke, E.W. & Dixit, V.M. (1998) Activation of caspase triggered by cytochrome c in vitro. FEBS Lett. 426, 151-154.
19. Perez, D. & White, E. (1998) E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE. J. Cell Biol. 141, 1255-1266.
20. Sakamaki, K., Tsukumo, S. & Yonehara, S. (1998) Molecular cloning and characterization of mouse caspase-8. Eur. J. Biochem. 253, 399-405.
21. Siegel, R.M., Martin, D.A., Zheng, L., et al. (1998) Death-effector filaments: novel cytoplasmic structures that recruit caspase and trigger apoptosis. J. Cell Biol. 141, 1243-1253.
22. Srinivasula, S.M., Ahmad, M., Fernandes-Alnemri, T. & Alnemri, E.S. (1998) Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol. Cell 1, 949-957.
23. Thome, M., Schneider, P., Hofmann, K., et al. (1997) Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 386, 517-521.
24. Yonehara, S., Ishii, A. & Yonehara, M. (1989) A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J. Exp. Med. 169, 1747-1756.
25. Zou, H., Henzel, W.J., Liu, X., Lutschg, A. & Wang, X. (1997) Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-4. Cell 90, 405-413.