Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors

Journal of Medicinal Chemistry

Volumn 43, Issue 10, 2000, Pages 2019-2030

  Corbett, Jeffrey W ^a   Ko, Soo S ^a   Rodgers, James D ^a   Gearhart, Lisa A ^a   Magnus, Nicholas A ^a   Bacheler, Lee T ^a   Diamond, Sharon ^a   Jeffrey, Susan ^a   Klabe, Ronald M ^a   Cordova, Beverly C ^a   Garber, Sena ^a   Logue, Kelly ^a   Trainor, George L ^a   Anderson, Paul S ^a   Erickson Viitanen, Susan K ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DELAVIRDINE; EFAVIRENZ; NEVIRAPINE; QUINAZOLINONE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

AMINO ACID SUBSTITUTION; ANTIVIRAL ACTIVITY; ARTICLE; DRUG EFFECT; DRUG POTENCY; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PROTEIN BINDING; VIRUS MUTANT; VIRUS REPLICATION;

ANTI-HIV AGENTS; BLOOD PROTEINS; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MOLECULAR STRUCTURE; MUTATION; OXAZINES; PROTEIN BINDING; QUINAZOLINES; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

EID: 0034128898     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990580e     Document Type: Article

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