Tat stimulates cotranscriptional capping of HIV mRNA

Molecular Cell

Volumn 10, Issue 3, 2002, Pages 585-597

  Chiu, Ya Lin ^a   Ho, C Kiong ^b   Saha, Nayanendu ^c   Schwer, Beate ^c   Shuman, Stewart ^b   Rana, Tariq M ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLTRANSFERASE; POL PROTEIN; PROTEIN; PROTEIN MCE1; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

ARTICLE; CAPPING PHENOMENON; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; METHYLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PROTEIN FUNCTION; RNA TRANSLATION; VIRUS GENE;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0036753540     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(02)00630-5     Document Type: Article

References (28)

1. Chiu Y.L., Coronel E., Ho C.K., Shuman S., Rana T.M. HIV-1 Tat protein interacts with mammalian capping enzyme and stimulates capping of TAR RNA. J. Biol. Chem. 276:2001;12959-12966.
2. Cho E.J., Takagi T., Moore C.R., Buratowski S. mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev. 11:1997;3319-3326.
3. Cho E.J., Kobor M.S., Kim M., Greenblatt J., Buratowski S. Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser2 of the RNA polymerase II C-terminal domain. Genes Dev. 15:2001;3319-3329.
4. Coppola J.A., Field A.S., Luse D.S. Promoter-proximal pausing by RNA polymerase II in vitro. transcripts shorter than 20 nucleotides are not capped Proc. Natl. Acad. Sci. USA. 80:1983;1251-1255.
5. Deng L., Hagler J., Shuman S. Factor-dependent release of nascent RNA by ternary complexes of vaccinia RNA polymerase. J. Biol. Chem. 271:1996;19556-19562.
6. Edery I., Chu L.L., Sonenberg N., Pelletier J. An efficient strategy to isolate full-length cDNAs based on an mRNA cap retention procedure (CAPture). Mol. Cell. Biol. 15:1995;3363-3371.
7. Hagler J., Shuman S. A freeze-frame view of eukaryotic transcription during elongation and capping of nascent mRNA. Science. 255:1992;983-986.
8. Hausmann S., Shuman S. Characterization of the CTD phosphatase Fcp1 from fission yeast. preferential dephosphorylation of serine 2 versus serine 5 J. Biol. Chem. 277:2002;21213-21220.
9. Ho C.K., Shuman S. Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme. Mol. Cell. 3:1999;405-411.
10. Ho C.K., Sriskanda V., McCracken S., Bentley D., Schwer B., Shuman S. The guanylyltransferase domain of mammalian mRNA capping enzyme binds to the phosphorylated carboxyl-terminal domain of RNA polymerase II. J. Biol. Chem. 273:1998;9577-9585.
11. Keen N.J., Gait M.J., Karn J. Human immunodeficiency virus type-1 tat is an integral component of the activated transcription-elongation complex. Proc. Natl. Acad. Sci. USA. 93:1996;2505-2510.
12. Komarnitsky P., Cho E.J., Buratowski S. Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev. 14:2000;2452-2460.
13. McCracken S., Fong N., Rosonina E., Yankulov K., Brothers G., Siderovski D., Hessel A., Foster S., Shuman S., Bentley D.L. 5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II. Genes Dev. 11:1997;3306-3318.
14. Pei Y., Shuman S. Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5. J. Biol. Chem. 277:2002;19639-19648.
15. Pei Y., Hausmann S., Ho C.K., Schwer B., Shuman S. The length, phosphorylation state, and primary structure of the RNA polymerase II carboxyl-terminal domain dictate interactions with mRNA capping enzymes. J. Biol. Chem. 276:2001;28075-28082.
16. Pillutla R.C., Yue Z., Maldonado E., Shatkin A.J. Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexes. J. Biol. Chem. 273:1998;21443-21446.
17. Ping Y.H., Rana T.M. Tat-associated kinase (P-TEFb). a component of transcription preinitiation and elongation complexes J. Biol. Chem. 274:1999;7399-7404.
18. Ping Y.H., Rana T.M. DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation. J. Biol. Chem. 276:2001;12951-12958.
19. Price D.H. P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II. Mol. Cell. Biol. 20:2000;2629-2634.
20. Rasmussen E.B., Lis J.T. In vivo transcriptional pausing and cap formation on three Drosophila heat shock genes. Proc. Natl. Acad. Sci. USA. 90:1993;7923-7927.
21. Rhim H., Echetebu C.O., Herrmann C.H., Rice A.P. Wild-type and mutant HIV-1 and HIV-2 Tat proteins expressed in Escherichia coli as fusions with glutathione S-transferase. J. Acquir. Immune Defic. Syndr. 7:1994;1116-1121.
22. Rodriguez C.R., Cho E.J., Heogh M.C., Moore C.L., Greenleaf A.L., Buratowski S. Kin28, ther TFIIH-associated carboxyl-terminal domain kinase, facilitates recruitment of mRNA processing machinery to RNA polymerase II. Mol. Cell. Biol. 20:2000;104-112.
23. Saha N., Schwer B., Shuman S. Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes. J. Biol. Chem. 274:1999;16553-16562.
24. Schroeder S., Schwer B., Shuman S., Bentley D. Dynamic association of capping enzymes with transcribing RNA polymerase II. Genes Dev. 14:2000;2435-2440.
25. Wei P., Garber M.E., Fang S.M., Fischer W.H., Jones K.A. A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell. 92:1998;451-462.
26. Wen Y., Shatkin A.J. Transcription elongation factor hSPT5 stimulates mRNA capping. Genes Dev. 13:1999;1774-1779.
27. Yue Z., Maldonado E., Pillutla R., Cho H., Reinberg D., Shatkin A.J. Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II. Proc. Natl. Acad. Sci. USA. 94:1997;12898-12903.
28. Zhou C., Rana T.M. A bimolecular mechanism of HIV-1 Tat protein interaction with RNA polymerase II transcription elongation complexes. J. Mol. Biol. 320:2002;925-942.