Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: A platform for antiviral drug design

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 23, 1999, Pages 13040-13043

  Goldgur, Yehuda ^a   Craigie, Robert ^a   Cohen, Gerson H ^a   Fujiwara, Tamio ^b   Yoshinaga, Tomokazu ^b   Fujishita, Toshio ^b   Sugimoto, Hirohiko ^b   Endo, Takeshi ^b   Murai, Hitoshi ^b   Davies, David R ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b SHIONOGI AND CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE; INTEGRASE INHIBITOR;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; DRUG DESIGN; ENZYME ACTIVE SITE; ENZYME SUBUNIT; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; VIRUS MORPHOLOGY;

BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; INDOLES; MODELS, MOLECULAR; PROTEIN CONFORMATION; TETRAZOLES;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MAMMALIA; RNA VIRUSES;

EID: 13044295993     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.23.13040     Document Type: Article

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