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Volumn 62, Issue 21, 2005, Pages 2438-2459

Functional and physical communication between oncoproteins and tumor suppressors

Author keywords

CIN; Cyclins; E2F; Fanconi's anemia; Genomic instability; MIN; Myc; p53, Rb; Peroxiredoxin

Indexed keywords

ALPHA TOCOPHEROL; APC PROTEIN; ASCORBIC ACID; CAROTENOID; CYCLIN D1; CYCLIN D2; CYCLIN DEPENDENT KINASE; CYCLIN E; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MISMATCH REPAIR PROTEIN PMS2; MIXED LINEAGE KINASE 3; ONCOPROTEIN; PEROXIREDOXIN; PROTEIN KINASE; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH3; PROTEIN MSH6; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RETINOBLASTOMA PROTEIN; SELENIUM; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TUMOR SUPPRESSOR PROTEIN;

EID: 29144504350     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-005-5199-8     Document Type: Review
Times cited : (10)

References (180)
  • 1
    • 0017250977 scopus 로고
    • DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA
    • Stehelin D., Varmus H. E., Bishop J. M. and Vogt P.K. (1976) DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature 260: 170-173
    • (1976) Nature , vol.260 , pp. 170-173
    • Stehelin, D.1    Varmus, H.E.2    Bishop, J.M.3    Vogt, P.K.4
  • 2
    • 0020972413 scopus 로고
    • Cellular oncogenes and retroviruses
    • Bishop J. M. (1983) Cellular oncogenes and retroviruses. Annu. Rev. Biochem. 52: 301-354
    • (1983) Annu. Rev. Biochem. , vol.52 , pp. 301-354
    • Bishop, J.M.1
  • 3
    • 0019504253 scopus 로고
    • Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis
    • Hayward W. S., Neel B. G. and Astrin S. M. (1981) Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis. Nature 290: 475-480
    • (1981) Nature , vol.290 , pp. 475-480
    • Hayward, W.S.1    Neel, B.G.2    Astrin, S.M.3
  • 4
    • 0020669676 scopus 로고
    • Transforming genes of tumor cells
    • Weinberg R. A. (1983) Transforming genes of tumor cells. Int. Rev. Cytol. Suppl. 15: 191-202
    • (1983) Int. Rev. Cytol. Suppl. , vol.15 , pp. 191-202
    • Weinberg, R.A.1
  • 5
    • 0021074016 scopus 로고
    • Induction of mammary carcinomas in rats by nitrosomethylurea involves malignant activation of H-ras-1 locus by single point mutations
    • Sukumar S., Notario V., Martin-Zanca D. and Barbacid M. (1983) Induction of mammary carcinomas in rats by nitrosomethylurea involves malignant activation of H-ras-1 locus by single point mutations. Nature 306: 658-661
    • (1983) Nature , vol.306 , pp. 658-661
    • Sukumar, S.1    Notario, V.2    Martin-Zanca, D.3    Barbacid, M.4
  • 6
    • 0033551374 scopus 로고    scopus 로고
    • MYC oncogenes and human neoplastic disease
    • Nesbit C. E., Tersak J. M. and Prochownik E. V. (1999) MYC oncogenes and human neoplastic disease. Oncogene 18: 3004-3016
    • (1999) Oncogene , vol.18 , pp. 3004-3016
    • Nesbit, C.E.1    Tersak, J.M.2    Prochownik, E.V.3
  • 8
    • 0017161982 scopus 로고
    • Genetics and the etiology of childhood cancer
    • Knudson A. G. Jr (1976) Genetics and the etiology of childhood cancer. Pediatr. Res. 10: 513-517
    • (1976) Pediatr. Res. , vol.10 , pp. 513-517
    • Knudson Jr., A.G.1
  • 9
    • 0022506980 scopus 로고
    • A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
    • Friend S. H., Bernards R., Rogelj S., Weinberg R. A., Rapaport J. M., Albert D. M. et al. (1986) A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature. 323: 643-646
    • (1986) Nature , vol.323 , pp. 643-646
    • Friend, S.H.1    Bernards, R.2    Rogelj, S.3    Weinberg, R.A.4    Rapaport, J.M.5    Albert, D.M.6
  • 10
    • 0020682479 scopus 로고
    • Molecular cloning of a cDNA specific for the murine p53 cellular tumor antigen
    • USA
    • Oren M. and Levine A. J. (1983) Molecular cloning of a cDNA specific for the murine p53 cellular tumor antigen. Proc. Natl. Acad. Sci. USA 80: 56-59
    • (1983) Proc. Natl. Acad. Sci. , vol.80 , pp. 56-59
    • Oren, M.1    Levine, A.J.2
  • 11
    • 0020520516 scopus 로고
    • Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
    • Land H., Parada L. F. and Weinberg R. A. (1983) Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 304: 596-602
    • (1983) Nature , vol.304 , pp. 596-602
    • Land, H.1    Parada, L.F.2    Weinberg, R.A.3
  • 12
    • 0842346437 scopus 로고    scopus 로고
    • Principles of tumor suppression
    • Sherr C. J. (2004) Principles of tumor suppression. Cell 116: 235-246
    • (2004) Cell , vol.116 , pp. 235-246
    • Sherr, C.J.1
  • 13
    • 0035063183 scopus 로고    scopus 로고
    • The Rb/E2F pathway and cancer
    • Nevins J. R. (2001) The Rb/E2F pathway and cancer. Hum. Mol. Genet. 10: 699-703
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 699-703
    • Nevins, J.R.1
  • 14
    • 0037313618 scopus 로고    scopus 로고
    • Coordinated regulation of life and death by RB
    • Chau B. N. and Wang J. Y. (2003) Coordinated regulation of life and death by RB. Nat. Rev. Cancer 3: 130-138
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 130-138
    • Chau, B.N.1    Wang, J.Y.2
  • 15
    • 0036884829 scopus 로고    scopus 로고
    • The retinoblastoma tumour suppressor in development and cancer
    • Classon M. and Harlow E. (2002) The retinoblastoma tumour suppressor in development and cancer. Nat. Rev. Cancer 2: 910-917
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 910-917
    • Classon, M.1    Harlow, E.2
  • 16
    • 2942722811 scopus 로고    scopus 로고
    • Molecular mechanisms of E2F-dependent activation and pRB-mediated repression
    • Frolov M. V. and Dyson N. J. (2004) Molecular mechanisms of E2F-dependent activation and pRB-mediated repression. J. Cell. Sci. 117: 2173-2181
    • (2004) J. Cell. Sci. , vol.117 , pp. 2173-2181
    • Frolov, M.V.1    Dyson, N.J.2
  • 17
    • 0037075898 scopus 로고    scopus 로고
    • Activation of the p53 tumor suppressor protein
    • Vousden K. H. (2002) Activation of the p53 tumor suppressor protein. Biochim. Biophys. Acta 1602: 47-59
    • (2002) Biochim. Biophys. Acta , vol.1602 , pp. 47-59
    • Vousden, K.H.1
  • 18
    • 0035868379 scopus 로고    scopus 로고
    • Expression analysis using DNA microarrays demonstrates that E2F-1 up-regulates expression of DNA replication genes including replication protein A2
    • Kalma Y., Marash L., Lamed Y. and Ginsberg D. (2001) Expression analysis using DNA microarrays demonstrates that E2F-1 up-regulates expression of DNA replication genes including replication protein A2. Oncogene 20: 1379-1387
    • (2001) Oncogene , vol.20 , pp. 1379-1387
    • Kalma, Y.1    Marash, L.2    Lamed, Y.3    Ginsberg, D.4
  • 19
    • 0035252592 scopus 로고    scopus 로고
    • E2Fs regulate the expression of genes involved in differentiation, development, proliferation and apoptosis
    • Muller H., Bracken A. P., Vernell R., Moroni M. C., Christians F., Grassilli E. et al. (2001) E2Fs regulate the expression of genes involved in differentiation, development, proliferation and apoptosis. Genes Dev. 15: 267-285
    • (2001) Genes Dev. , vol.15 , pp. 267-285
    • Muller, H.1    Bracken, A.P.2    Vernell, R.3    Moroni, M.C.4    Christians, F.5    Grassilli, E.6
  • 20
    • 0034306996 scopus 로고    scopus 로고
    • The Rb/E2F pathway: Expanding roles and emerging paradigms
    • Harbour J. W. and Dean D. C. (2000) The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev. 14: 2393-3409
    • (2000) Genes Dev. , vol.14 , pp. 2393-3409
    • Harbour, J.W.1    Dean, D.C.2
  • 21
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr C. J. and Roberts J. M. (1999) CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13: 1501-1512
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 22
    • 0029283863 scopus 로고
    • Cyclin D1 as a cellular proto-oncogene
    • Bates S. and Peters G. (1995) Cyclin D1 as a cellular proto-oncogene. Semin. Cancer Biol. 6: 73-82
    • (1995) Semin. Cancer Biol. , vol.6 , pp. 73-82
    • Bates, S.1    Peters, G.2
  • 23
    • 0036491040 scopus 로고    scopus 로고
    • Molecular pathogenesis of rhabdomyosarcoma
    • Xia S. J., Pressey J. G. and Barr F. G. (2002) Molecular pathogenesis of rhabdomyosarcoma. Cancer Biol. Ther. 1: 97-104
    • (2002) Cancer Biol. Ther. , vol.1 , pp. 97-104
    • Xia, S.J.1    Pressey, J.G.2    Barr, F.G.3
  • 24
    • 0344301900 scopus 로고    scopus 로고
    • Role of the p16 tumor suppressor gene in cancer
    • Liggett W. H. Jr and Sidransky D. (1998) Role of the p16 tumor suppressor gene in cancer. J. Clin. Oncol. 16: 1197-1206
    • (1998) J. Clin. Oncol. , vol.16 , pp. 1197-1206
    • Liggett Jr., W.H.1    Sidransky, D.2
  • 27
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • Lane D. P. (1992) p53, guardian of the genome. Nature 358: 15-16
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 28
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • Vousden K. H. and Lu X. (2002) Live or let die: the cell's response to p53. Nat. Rev. Cancer. 2: 594-604
    • (2002) Nat. Rev. Cancer. , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 29
    • 0029587551 scopus 로고
    • Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle D. E., Zindy F., Ashmun R. A. and Sherr C. J. (1995) Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 83: 993-1000
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 31
    • 0035895622 scopus 로고    scopus 로고
    • Pathways governing G1/S transition and their response to DNA damage
    • Bartek J. and Lukas J. (2001) Pathways governing G1/S transition and their response to DNA damage. FEBS Lett. 490: 117-122
    • (2001) FEBS Lett. , vol.490 , pp. 117-122
    • Bartek, J.1    Lukas, J.2
  • 32
    • 0029827771 scopus 로고    scopus 로고
    • A role for a p21-E2F interaction during senescence arrest of normal human fibroblasts
    • Afshari C. A., Nichols M. A., Xiong Y. and Mudryj M. (1996) A role for a p21-E2F interaction during senescence arrest of normal human fibroblasts. Cell Growth Differ. 7: 979-988
    • (1996) Cell Growth Differ , vol.7 , pp. 979-988
    • Afshari, C.A.1    Nichols, M.A.2    Xiong, Y.3    Mudryj, M.4
  • 33
    • 0037309326 scopus 로고    scopus 로고
    • Tumor suppression by Ink4a-Arf: Progress and puzzles
    • Lowe S. W. and Sherr C. J. (2003) Tumor suppression by Ink4a-Arf: progress and puzzles. Curr. Opin. Genet. Dev. 13: 77-83
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 77-83
    • Lowe, S.W.1    Sherr, C.J.2
  • 34
    • 12744269233 scopus 로고    scopus 로고
    • Role of the proto-oncogene Pokemon in cellular transformation and ARF repression
    • Maeda T., Hobbs R. M., Merghoub T., Guernah I., Zelent A., Cordon-Cardo C. et al. (2005) Role of the proto-oncogene Pokemon in cellular transformation and ARF repression. Nature 433: 278-285
    • (2005) Nature , vol.433 , pp. 278-285
    • Maeda, T.1    Hobbs, R.M.2    Merghoub, T.3    Guernah, I.4    Zelent, A.5    Cordon-Cardo, C.6
  • 35
    • 0030696925 scopus 로고    scopus 로고
    • Malignant transformation by cyclin e and Ha-Ras correlates with lower sensitivity towards induction of cell death but requires functional Myc and CDK4
    • Haas K., Johannes C., Geisen C., Schmidt T., Karsunky H., Blass-Kampmann S. et al. (1997) Malignant transformation by cyclin E and Ha-Ras correlates with lower sensitivity towards induction of cell death but requires functional Myc and CDK4. Oncogene 15: 2615-2623
    • (1997) Oncogene , vol.15 , pp. 2615-2623
    • Haas, K.1    Johannes, C.2    Geisen, C.3    Schmidt, T.4    Karsunky, H.5    Blass-Kampmann, S.6
  • 36
    • 0037075887 scopus 로고    scopus 로고
    • Cyclin D-dependent kinases, INK4 inhibitors and cancer
    • Ortega S., Malumbres M. and Barbacid M. (2002) Cyclin D-dependent kinases, INK4 inhibitors and cancer. Biochim. Biophys. Acta 1602: 73-87
    • (2002) Biochim. Biophys. Acta , vol.1602 , pp. 73-87
    • Ortega, S.1    Malumbres, M.2    Barbacid, M.3
  • 38
    • 0021720781 scopus 로고
    • Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes
    • Stewart T. A., Pattengale P. K. and Leder P. (1984) Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell 38: 627-637
    • (1984) Cell , vol.38 , pp. 627-637
    • Stewart, T.A.1    Pattengale, P.K.2    Leder, P.3
  • 39
    • 0023631608 scopus 로고
    • Coexpression of MMTV/v-Ha-ras and MMTV/ c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo
    • Sinn E., Muller W., Pattengale P., Tepler I., Wallace R. and Leder P. (1987) Coexpression of MMTV/v-Ha-ras and MMTV/ c-myc genes in transgenic mice: synergistic action of oncogenes in vivo. Cell 49: 465-475
    • (1987) Cell , vol.49 , pp. 465-475
    • Sinn, E.1    Muller, W.2    Pattengale, P.3    Tepler, I.4    Wallace, R.5    Leder, P.6
  • 40
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler K. W. and Vogelstein B. (1996) Lessons from hereditary colorectal cancer. Cell 87: 159-170
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 41
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D. and Weinberg R. A. (2000) The hallmarks of cancer. Cell 100: 57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 42
    • 0036561908 scopus 로고    scopus 로고
    • Modelling the molecular circuitry of cancer
    • Hahn W. C. and Weinberg R. A. (2002) Modelling the molecular circuitry of cancer. Nat. Rev. Cancer 2: 331-341
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 331-341
    • Hahn, W.C.1    Weinberg, R.A.2
  • 43
    • 0016176530 scopus 로고
    • Errors in DNA replication as a basis of malignant changes
    • Loeb L. A., Springgate C. F. and Battula N. (1974) Errors in DNA replication as a basis of malignant changes. Cancer Res. 34: 2311-2321
    • (1974) Cancer Res. , vol.34 , pp. 2311-2321
    • Loeb, L.A.1    Springgate, C.F.2    Battula, N.3
  • 44
    • 10944257674 scopus 로고    scopus 로고
    • Crosslinks and crosstalk: Human cancer syndromes and DNA repair defects
    • Risinger M. A. and Groden J. (2004) Crosslinks and crosstalk: human cancer syndromes and DNA repair defects. Cancer Cell 6: 539-545
    • (2004) Cancer Cell , vol.6 , pp. 539-545
    • Risinger, M.A.1    Groden, J.2
  • 46
    • 0030932869 scopus 로고    scopus 로고
    • Cancer-susceptibility genes. Gatekeepers and caretakers
    • Kinzler K. W. and Vogelstein B. (1997) Cancer-susceptibility genes. Gatekeepers and caretakers. Nature 386: 761, 763
    • (1997) Nature , vol.386 , pp. 761
    • Kinzler, K.W.1    Vogelstein, B.2
  • 47
    • 0034958108 scopus 로고    scopus 로고
    • Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice
    • Goldsby R. E., Lawrence N. A., Hays L. E., Olmsted E. A., Chen X., Singh M. et al. (2001) Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice. Nat. Med. 7: 638-639
    • (2001) Nat. Med. , vol.7 , pp. 638-639
    • Goldsby, R.E.1    Lawrence, N.A.2    Hays, L.E.3    Olmsted, E.A.4    Chen, X.5    Singh, M.6
  • 48
    • 0036099467 scopus 로고    scopus 로고
    • Centrosome replication, genomic instability and cancer
    • Kramer A, Neben K. and Ho A. D. (2002) Centrosome replication, genomic instability and cancer. Leukemia 16: 767-775
    • (2002) Leukemia , vol.16 , pp. 767-775
    • Kramer, A.1    Neben, K.2    Ho, A.D.3
  • 49
    • 0029023147 scopus 로고
    • Microsatellite instability and K-ras mutations associated with pancreatic adenocarcinoma and pancreatitis
    • Brentnall T. A., Chen R., Lee J. G., Kimmey M. B., Bronner M. P., Haggitt R. C. et al. (1995) Microsatellite instability and K-ras mutations associated with pancreatic adenocarcinoma and pancreatitis. Cancer Res. 55: 4264-4267
    • (1995) Cancer Res. , vol.55 , pp. 4264-4267
    • Brentnall, T.A.1    Chen, R.2    Lee, J.G.3    Kimmey, M.B.4    Bronner, M.P.5    Haggitt, R.C.6
  • 50
    • 0029937720 scopus 로고    scopus 로고
    • Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis
    • Brentnall T. A., Crispin D. A., Bronner M. P., Cherian S. P., Hueffed M., Rabinovitch P. S. et al. (1996) Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis. Cancer Res. 56: 12337-12340
    • (1996) Cancer Res. , vol.56 , pp. 12337-12340
    • Brentnall, T.A.1    Crispin, D.A.2    Bronner, M.P.3    Cherian, S.P.4    Hueffed, M.5    Rabinovitch, P.S.6
  • 51
    • 0037469102 scopus 로고    scopus 로고
    • Microsatellite alterations in esophageal dysplasia and squamous cell carcinoma from laser capture microdissected endoscopic biopsies
    • Lu N., Hu N., Li W. J., Roth M. J., Wang C., Su H. et al. (2003) Microsatellite alterations in esophageal dysplasia and squamous cell carcinoma from laser capture microdissected endoscopic biopsies. Cancer Lett. 189: 137-145
    • (2003) Cancer Lett. , vol.189 , pp. 137-145
    • Lu, N.1    Hu, N.2    Li, W.J.3    Roth, M.J.4    Wang, C.5    Su, H.6
  • 52
    • 0037390446 scopus 로고    scopus 로고
    • The hereditary nonpolyposis colorectal cancer syndrome: Genetics and clinical implications
    • Chung D. C. and Rustgi A. K. (2003) The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implications. Ann. Intern. Med. 138: 560-570
    • (2003) Ann. Intern. Med. , vol.138 , pp. 560-570
    • Chung, D.C.1    Rustgi, A.K.2
  • 55
    • 4243308292 scopus 로고    scopus 로고
    • Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine
    • USA
    • Toft N. J., Winton D. J., Kelly J., Howard L. A., Dekker M., te Riele H. et al. (1999) Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine. Proc. Natl. Acad. Sci. USA 96: 3911-3915
    • (1999) Proc. Natl. Acad. Sci. , vol.96 , pp. 3911-3915
    • Toft, N.J.1    Winton, D.J.2    Kelly, J.3    Howard, L.A.4    Dekker, M.5    Te Riele, H.6
  • 56
    • 9144271661 scopus 로고    scopus 로고
    • The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation
    • Hofseth L. J., Khan M. A., Ambrose M., Nikolayeva O., XuWelliver M., Kartalou M. et al. (2003) The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. J. Clin. Invest. 112: 1887-1894
    • (2003) J. Clin. Invest. , vol.112 , pp. 1887-1894
    • Hofseth, L.J.1    Khan, M.A.2    Ambrose, M.3    Nikolayeva, O.4    Xuwelliver, M.5    Kartalou, M.6
  • 57
    • 0025137506 scopus 로고
    • Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae
    • Spencer F., Gerring S. L., Connelly C. and Hieter P. (1990) Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae. Genetics 124: 237-249
    • (1990) Genetics , vol.124 , pp. 237-249
    • Spencer, F.1    Gerring, S.L.2    Connelly, C.3    Hieter, P.4
  • 58
    • 0035110871 scopus 로고    scopus 로고
    • Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis
    • Shih I. M., Zhou W., Goodman S. N., Lengauer C., Kinzler K. W. and Vogelstein B. (2001) Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis. Cancer Res. 61: 818-822
    • (2001) Cancer Res. , vol.61 , pp. 818-822
    • Shih, I.M.1    Zhou, W.2    Goodman, S.N.3    Lengauer, C.4    Kinzler, K.W.5    Vogelstein, B.6
  • 60
    • 0026663080 scopus 로고
    • DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis
    • Rubin C. E., Haggitt R. C., Burmer G. C., Brentnall T. A., Stevens A. C., Levine D. S. et al. (1992) DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis. Gastroenterology 103: 1611-1620
    • (1992) Gastroenterology , vol.103 , pp. 1611-1620
    • Rubin, C.E.1    Haggitt, R.C.2    Burmer, G.C.3    Brentnall, T.A.4    Stevens, A.C.5    Levine, D.S.6
  • 61
    • 14244253990 scopus 로고    scopus 로고
    • Essential tension and constructive destruction: The spindle checkpoint and its regulatory links with mitotic exit
    • Tan A. L., Rida P. C. and Surana U. (2005) Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit. Biochem. J. 386: 1-13
    • (2005) Biochem. J. , vol.386 , pp. 1-13
    • Tan, A.L.1    Rida, P.C.2    Surana, U.3
  • 62
    • 4444381521 scopus 로고    scopus 로고
    • The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint
    • Acquaviva C., Herzog F., Kraft C. and Pines J. (2004) The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint. Nat. Cell Biol. 6: 892-898
    • (2004) Nat. Cell Biol. , vol.6 , pp. 892-898
    • Acquaviva, C.1    Herzog, F.2    Kraft, C.3    Pines, J.4
  • 63
    • 7744233719 scopus 로고    scopus 로고
    • Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint
    • Rieder C. L. and Maiato H. (2004) Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint. Dev. Cell. 7: 637-651
    • (2004) Dev. Cell. , vol.7 , pp. 637-651
    • Rieder, C.L.1    Maiato, H.2
  • 64
    • 0035694452 scopus 로고    scopus 로고
    • Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells
    • Taylor S. S., Hussein D., Wang Y., Elderkin S. and Morrow C. J. (2001) Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells. J. Cell Sci. 114: 4385-4395
    • (2001) J. Cell Sci. , vol.114 , pp. 4385-4395
    • Taylor, S.S.1    Hussein, D.2    Wang, Y.3    Elderkin, S.4    Morrow, C.J.5
  • 66
    • 4344610852 scopus 로고    scopus 로고
    • Timing and checkpoints in the regulation of mitotic progression
    • Meraldi P., Draviam V. M. and Sorger P. K. (2004) Timing and checkpoints in the regulation of mitotic progression. Dev. Cell. 7: 45-60
    • (2004) Dev. Cell. , vol.7 , pp. 45-60
    • Meraldi, P.1    Draviam, V.M.2    Sorger, P.K.3
  • 68
    • 0032415593 scopus 로고    scopus 로고
    • GFP tagging reveals human Polo-like kinase 1 at the kinetochore/ centromere region of mitotic chromosomes
    • Arnaud L., Pines J. and Nigg E. A. (1998) GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes. Chromosoma 107: 424-429
    • (1998) Chromosoma , vol.107 , pp. 424-429
    • Arnaud, L.1    Pines, J.2    Nigg, E.A.3
  • 69
    • 0035906861 scopus 로고    scopus 로고
    • Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast
    • Alexandru G., Uhlmann F., Mechtler K., Poupart M. A. and Nasmyth K. (2001) Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast. Cell 105: 459-472
    • (2001) Cell , vol.105 , pp. 459-472
    • Alexandru, G.1    Uhlmann, F.2    Mechtler, K.3    Poupart, M.A.4    Nasmyth, K.5
  • 70
    • 9144253124 scopus 로고    scopus 로고
    • Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency
    • Dai W., Wang Q., Liu T., Swamy M., Fang Y., Xie S. et al. (2004) Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency. Cancer Res. 64: 440-445
    • (2004) Cancer Res. , vol.64 , pp. 440-445
    • Dai, W.1    Wang, Q.2    Liu, T.3    Swamy, M.4    Fang, Y.5    Xie, S.6
  • 71
    • 0035905811 scopus 로고    scopus 로고
    • MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells
    • Michel L. S., Liberal V., Chatterjee A., Kirchwegger R., Pasche B., Gerald W et al. (2001) MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells. Nature 409: 355-359
    • (2001) Nature , vol.409 , pp. 355-359
    • Michel, L.S.1    Liberal, V.2    Chatterjee, A.3    Kirchwegger, R.4    Pasche, B.5    Gerald, W.6
  • 73
    • 0035524309 scopus 로고    scopus 로고
    • Chromosome segregation and cancer: Cutting through the mystery
    • Jallepalli P. V. and Lengauer C. (2001) Chromosome segregation and cancer: cutting through the mystery. Nat. Rev. Cancer 1: 109-117
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 109-117
    • Jallepalli, P.V.1    Lengauer, C.2
  • 74
    • 0030910680 scopus 로고    scopus 로고
    • Isolation and characterization of a pituitary tumor-transforming gene (PTTG)
    • Pei L. and Melmed S. (1997) Isolation and characterization of a pituitary tumor-transforming gene (PTTG). Mol. Endocrinol. 11: 433-441
    • (1997) Mol. Endocrinol. , vol.11 , pp. 433-441
    • Pei, L.1    Melmed, S.2
  • 75
    • 10644258336 scopus 로고    scopus 로고
    • Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
    • Hanks S., Coleman K., Reid S., Plaja A., Firth H., Fitzpatrick D. et al. (2004) Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B. Nat. Genet. 36: 1159-1161
    • (2004) Nat. Genet. , vol.36 , pp. 1159-1161
    • Hanks, S.1    Coleman, K.2    Reid, S.3    Plaja, A.4    Firth, H.5    Fitzpatrick, D.6
  • 76
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B. and Kinzler K. W. (2004) Cancer genes and the pathways they control. Nat. Med. 10: 789-799
    • (2004) Nat. Med. , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 77
    • 1642430935 scopus 로고    scopus 로고
    • Wnt breakers in colon cancer
    • Clevers H. (2004) Wnt breakers in colon cancer. Cancer Cell 5: 5-6
    • (2004) Cancer Cell , vol.5 , pp. 5-6
    • Clevers, H.1
  • 78
    • 0033521884 scopus 로고    scopus 로고
    • C-myc overexpression and p53 loss cooperate to promote genomic instability
    • Yin X. Y., Grove L., Datta N. S., Long M. W. and Prochownik E. V. (1999) C-myc overexpression and p53 loss cooperate to promote genomic instability. Oncogene 18: 1177-1184
    • (1999) Oncogene , vol.18 , pp. 1177-1184
    • Yin, X.Y.1    Grove, L.2    Datta, N.S.3    Long, M.W.4    Prochownik, E.V.5
  • 79
    • 0043193855 scopus 로고    scopus 로고
    • Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression
    • USA
    • Karlsson A., Deb-Basu D., Cherry A., Turner S., Ford J. and Felsher D/W. (2003) Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression. Proc. Natl. Acad. Sci. USA 100: 9974-9979
    • (2003) Proc. Natl. Acad. Sci. , vol.100 , pp. 9974-9979
    • Karlsson, A.1    Deb-Basu, D.2    Cherry, A.3    Turner, S.4    Ford, J.5    Felsher, D.W.6
  • 82
    • 0032168986 scopus 로고    scopus 로고
    • The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules
    • USA
    • Berrueta L., Kraeft S. K., Tirnauer J. S., Schuyler S. C., Chen L. B., Hill D. E. et al. (1998) The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules. Proc. Natl. Acad. Sci. USA 95: 10596-10601
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 10596-10601
    • Berrueta, L.1    Kraeft, S.K.2    Tirnauer, J.S.3    Schuyler, S.C.4    Chen, L.B.5    Hill, D.E.6
  • 83
    • 26244449529 scopus 로고    scopus 로고
    • Emerging roles of centrosomal amplification and genomic instability in cancer
    • Emdad L., Sarkar D., Su Z. Z. and Fisher P. B. (2005) Emerging roles of centrosomal amplification and genomic instability in cancer. Front Biosci. 10: 728-742
    • (2005) Front Biosci. , vol.10 , pp. 728-742
    • Emdad, L.1    Sarkar, D.2    Su, Z.Z.3    Fisher, P.B.4
  • 84
    • 0030979677 scopus 로고    scopus 로고
    • Genomic instability and apoptosis are frequent in p53 deficient young mice
    • Fukasawa K., Wiener F., Vande Woude G. F. and Mai S. (1997) Genomic instability and apoptosis are frequent in p53 deficient young mice. Oncogene 15: 1295-1302
    • (1997) Oncogene , vol.15 , pp. 1295-1302
    • Fukasawa, K.1    Wiener, F.2    Vande Woude, G.F.3    Mai, S.4
  • 85
    • 0037048323 scopus 로고    scopus 로고
    • Loss of p53 and centrosome hyperamplification
    • Tarapore P. and Fukasawa K. (2002) Loss of p53 and centrosome hyperamplification. Oncogene 21: 6234-6240
    • (2002) Oncogene , vol.21 , pp. 6234-6240
    • Tarapore, P.1    Fukasawa, K.2
  • 86
    • 0034630156 scopus 로고    scopus 로고
    • p53 localizes to the centrosomes and spindles of mitotic cells in the embryonic chick epiblast, human cell lines and a human primary culture: An immunofluorescence study
    • Morris V. B., Brammall J., Noble J. and Reddel R. (2000) p53 localizes to the centrosomes and spindles of mitotic cells in the embryonic chick epiblast, human cell lines and a human primary culture: an immunofluorescence study. Exp. Cell Res. 256: 122-130
    • (2000) Exp. Cell Res. , vol.256 , pp. 122-130
    • Morris, V.B.1    Brammall, J.2    Noble, J.3    Reddel, R.4
  • 87
    • 4644259577 scopus 로고    scopus 로고
    • Induction of centrosome amplification and chromosome instability in p53-null cells by transient exposure to subtoxic levels of S-phase-targeting anticancer drugs
    • Bennett R. A., Izumi H. and Fukasawa K. (2004) Induction of centrosome amplification and chromosome instability in p53-null cells by transient exposure to subtoxic levels of S-phase-targeting anticancer drugs. Oncogene 23: 6823-6829
    • (2004) Oncogene , vol.23 , pp. 6823-6829
    • Bennett, R.A.1    Izumi, H.2    Fukasawa, K.3
  • 88
    • 1242338787 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 and E7 cause polyploidy in human keratinocytes and up-regulation of G2-M-phase proteins
    • Patel D., Incassati A., Wang N. and McCance D. J. (2004) Human papillomavirus type 16 E6 and E7 cause polyploidy in human keratinocytes and up-regulation of G2-M-phase proteins. Cancer Res. 64: 1299-1306
    • (2004) Cancer Res. , vol.64 , pp. 1299-1306
    • Patel, D.1    Incassati, A.2    Wang, N.3    McCance, D.J.4
  • 90
    • 10344230981 scopus 로고    scopus 로고
    • A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint
    • USA
    • Wang R. H., Yu H. and Deng C. X. (2004) A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint. Proc. Natl. Acad. Sci. USA 101: 17108-17113
    • (2004) Proc. Natl. Acad. Sci. , vol.101 , pp. 17108-17113
    • Wang, R.H.1    Yu, H.2    Deng, C.X.3
  • 91
    • 3543010169 scopus 로고    scopus 로고
    • Life, death, and tax: Role of HTLV-I oncoprotein in genetic instability and cellular transformation
    • Jeang K. T., Giam C. Z., Majone F. and Aboud M. (2004) Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation. J. Biol. Chem. 279: 31991-31994
    • (2004) J. Biol. Chem. , vol.279 , pp. 31991-31994
    • Jeang, K.T.1    Giam, C.Z.2    Majone, F.3    Aboud, M.4
  • 92
    • 0042091986 scopus 로고    scopus 로고
    • Human T-lymphotropic virus type 1 oncoprotein tax promotes unscheduled degradation of Pds1p/securin and Clb2p/cyclin B1 and causes chromosomal instability
    • Liu B., Liang M. H., Kuo Y. L., Liao W., Boros I., Kleinberger T. et al. (2003) Human T-lymphotropic virus type 1 oncoprotein tax promotes unscheduled degradation of Pds1p/securin and Clb2p/cyclin B1 and causes chromosomal instability. Mol. Cell Biol. 23: 5269-5281
    • (2003) Mol. Cell Biol. , vol.23 , pp. 5269-5281
    • Liu, B.1    Liang, M.H.2    Kuo, Y.L.3    Liao, W.4    Boros, I.5    Kleinberger, T.6
  • 93
    • 11844249376 scopus 로고    scopus 로고
    • HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule
    • USA
    • Liu B., Hong S., Tang, Z., Yu, H. and Giam C-Z. (2005) HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule. Proc. Natl. Acad. Sci. USA 102: 63-68
    • (2005) Proc. Natl. Acad. Sci. , vol.102 , pp. 63-68
    • Liu, B.1    Hong, S.2    Tang, Z.3    Yu, H.4    Giam, C.-Z.5
  • 94
    • 0035418188 scopus 로고    scopus 로고
    • Inverse regulation of cyclin B1 by c-Myc and p53 and induction of tetraploidy by cyclin B1 overexpression
    • Yin X. Y., Grove L., Datta N. S., Katula K., Long M. W. and Prochownik E. V. (2001) Inverse regulation of cyclin B1 by c-Myc and p53 and induction of tetraploidy by cyclin B1 overexpression. Cancer Res. 61: 6487-6493
    • (2001) Cancer Res. , vol.61 , pp. 6487-6493
    • Yin, X.Y.1    Grove, L.2    Datta, N.S.3    Katula, K.4    Long, M.W.5    Prochownik, E.V.6
  • 96
    • 0037655970 scopus 로고    scopus 로고
    • Unmasking the S-phase-promoting potential of cyclin B1
    • Moore J. D., Kirk J. A. and Hunt T. (2003) Unmasking the S-phase-promoting potential of cyclin B1. Science 300: 987-990
    • (2003) Science , vol.300 , pp. 987-990
    • Moore, J.D.1    Kirk, J.A.2    Hunt, T.3
  • 97
    • 0037057510 scopus 로고    scopus 로고
    • Are there two sides to colorectal cancer?
    • Iacopetta B. (2002) Are there two sides to colorectal cancer? Int. J. Cancer 101: 403-408
    • (2002) Int. J. Cancer , vol.101 , pp. 403-408
    • Iacopetta, B.1
  • 98
    • 0034642605 scopus 로고    scopus 로고
    • Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
    • ryfe R., Kim H., Hsieh E. ., Aronson M.D., Holowaty E. ., Bull S. . et al. (2000) Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. N. Engl. J. Med. 342: 69-77
    • (2000) N. Engl. J. Med. , vol.342 , pp. 69-77
    • Ryfe, R.1    Kim, H.2    Hsieh, E.3    Aronson, M.D.4    Holowaty, E.5    Bull, S.6
  • 99
    • 0033778049 scopus 로고    scopus 로고
    • Chromosomal instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy
    • Hemminki A., Mecklin J. P., Jarvinen H., Aaltonen L. A. and Joensuu H. (2000) Chromosomal instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy. Gastroenterology 119: 921-928
    • (2000) Gastroenterology , vol.119 , pp. 921-928
    • Hemminki, A.1    Mecklin, J.P.2    Jarvinen, H.3    Aaltonen, L.A.4    Joensuu, H.5
  • 100
    • 0034895979 scopus 로고    scopus 로고
    • p53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma
    • Elsaleh H., Powell B., McCaul K., Grieu F., Grant R. and Joseph D. et al. (2001) p53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma. Clin. Cancer Res. 7: 1343-1349
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1343-1349
    • Elsaleh, H.1    Powell, B.2    McCaul, K.3    Grieu, F.4    Grant, R.5    Joseph, D.6
  • 101
    • 85047698408 scopus 로고    scopus 로고
    • Gene expression differences between the microsatellite instability (MIN) and chromosomal instability (CIN) phenotypes in colorectal cancer revealed by high-density cDNA array hybridization
    • Dunican D. S., McWilliam P., Tighe O., Parle-McDermott A. and Croke D.T. (2002) Gene expression differences between the microsatellite instability (MIN) and chromosomal instability (CIN) phenotypes in colorectal cancer revealed by high-density cDNA array hybridization. Oncogene 21: 3253-3257
    • (2002) Oncogene , vol.21 , pp. 3253-3257
    • Dunican, D.S.1    McWilliam, P.2    Tighe, O.3    Parle-McDermott, A.4    Croke, D.T.5
  • 102
    • 0037373455 scopus 로고    scopus 로고
    • Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein
    • Marnett L. J., Riggins J. N. and West J. D. (2003) Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein. J. Clin. Invest. 111: 583-593
    • (2003) J. Clin. Invest. , vol.111 , pp. 583-593
    • Marnett, L.J.1    Riggins, J.N.2    West, J.D.3
  • 103
    • 0038799736 scopus 로고    scopus 로고
    • Oxidative DNA damage: Mechanisms, mutation and disease
    • Cooke M. S., Evans M. D., Dizdaroglu M.and Lunec J. (2003) Oxidative DNA damage: mechanisms, mutation and disease. FASEB J. 7: 1195-1214
    • (2003) FASEB J. , vol.7 , pp. 1195-1214
    • Cooke, M.S.1    Evans, M.D.2    Dizdaroglu, M.3    Lunec, J.4
  • 104
    • 0029886786 scopus 로고    scopus 로고
    • Cancer risk and oxidative DNA damage in man
    • Loft S. and Poulsen H. E. (1996) Cancer risk and oxidative DNA damage in man. J. Mol. Med. 74: 297-312
    • (1996) J. Mol. Med. , vol.74 , pp. 297-312
    • Loft, S.1    Poulsen, H.E.2
  • 106
    • 0035853157 scopus 로고    scopus 로고
    • Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
    • USA
    • Ramos-Gomez M., Kwak M. K., Dolan P. M., Itoh K., Yamamoto M., Talalay P. et al. (2001) Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc. Natl. Acad. Sci. USA 98: 3410-3415
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 3410-3415
    • Ramos-Gomez, M.1    Kwak, M.K.2    Dolan, P.M.3    Itoh, K.4    Yamamoto, M.5    Talalay, P.6
  • 107
    • 0042568938 scopus 로고    scopus 로고
    • Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression
    • Neumann C. A., Krause D. S., Carman C. V., Das S., Dubey D. P., Abraham J. L. et al. (2003) Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression. Nature 424: 561-565
    • (2003) Nature , vol.424 , pp. 561-565
    • Neumann, C.A.1    Krause, D.S.2    Carman, C.V.3    Das, S.4    Dubey, D.P.5    Abraham, J.L.6
  • 110
    • 18744426119 scopus 로고    scopus 로고
    • Peroxiredoxin I expression in oral cancer: A potential new tumor marker
    • Yanagawa T., Iwasa S., Ishii T., Tabuchi K., Yusa H., Onizawa K. et al. (2000) Peroxiredoxin I expression in oral cancer: a potential new tumor marker. Cancer Lett. 156: 27-35
    • (2000) Cancer Lett. , vol.156 , pp. 27-35
    • Yanagawa, T.1    Iwasa, S.2    Ishii, T.3    Tabuchi, K.4    Yusa, H.5    Onizawa, K.6
  • 111
    • 1342280365 scopus 로고    scopus 로고
    • Genomic annotation of the meningioma tumor suppressor locus on chromosome 1p34
    • Sulman E. P., White P. S. and Brodeur G. M. (2004) Genomic annotation of the meningioma tumor suppressor locus on chromosome 1p34. Oncogene 23: 1014-1020
    • (2004) Oncogene , vol.23 , pp. 1014-1020
    • Sulman, E.P.1    White, P.S.2    Brodeur, G.M.3
  • 112
    • 0030803669 scopus 로고    scopus 로고
    • The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity
    • Wen S. T. and Van Etten R. A. (1997) The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity. Genes Dev. 11: 2456-2467
    • (1997) Genes Dev. , vol.11 , pp. 2456-2467
    • Wen, S.T.1    Van Etten, R.A.2
  • 113
    • 0037044804 scopus 로고    scopus 로고
    • Pag, a putative tumor suppressor, interacts with the Myc Box II domain of c-Myc and selectively alters its biological function and target gene expression
    • Mu Z. M., Yin X. Y. and Prochownik E. V. (2002) Pag, a putative tumor suppressor, interacts with the Myc Box II domain of c-Myc and selectively alters its biological function and target gene expression. J. Biol. Chem. 277: 43175-43184
    • (2002) J. Biol. Chem. , vol.277 , pp. 43175-43184
    • Mu, Z.M.1    Yin, X.Y.2    Prochownik, E.V.3
  • 114
    • 3543084994 scopus 로고    scopus 로고
    • Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C delta
    • Li B., Wang X., Rasheed N., Hu Y., Boast S., Ishii T. et al. (2004) Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C delta. Genes Dev. 18: 1824-1837
    • (2004) Genes Dev. , vol.18 , pp. 1824-1837
    • Li, B.1    Wang, X.2    Rasheed, N.3    Hu, Y.4    Boast, S.5    Ishii, T.6
  • 116
    • 0036285034 scopus 로고    scopus 로고
    • c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability
    • Vafa O., Wade M., Kern S., Beeche M., Pandita T. K., Hampton G. M. et al. (2002) c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability.Mol. Cell. 9: 1031-1044
    • (2002) Mol. Cell. , vol.9 , pp. 1031-1044
    • Vafa, O.1    Wade, M.2    Kern, S.3    Beeche, M.4    Pandita, T.K.5    Hampton, G.M.6
  • 117
    • 0036478899 scopus 로고    scopus 로고
    • Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors
    • Al-Tassan N., Chmiel N. H., Maynard J., Fleming N., Livingston A. L., Williams G. T. et al. (2002) Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors. Nat. Genet. 30: 227-232
    • (2002) Nat. Genet. , vol.30 , pp. 227-232
    • Al-Tassan, N.1    Chmiel, N.H.2    Maynard, J.3    Fleming, N.4    Livingston, A.L.5    Williams, G.T.6
  • 118
    • 0037192812 scopus 로고    scopus 로고
    • Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6
    • Gu Y., Parker A., Wilson T. M., Bai H., Chang D. Y. and Lu A. L. (2002) Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6. J. Biol. Chem. 277: 11135-11142
    • (2002) J. Biol. Chem. , vol.277 , pp. 11135-11142
    • Gu, Y.1    Parker, A.2    Wilson, T.M.3    Bai, H.4    Chang, D.Y.5    Lu, A.L.6
  • 121
    • 0027315650 scopus 로고
    • A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice
    • Davis A. C., Wims M., Spotts G. D., Hann S. R. and Bradley A. (1993) A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice. Genes Dev. 7: 671-682
    • (1993) Genes Dev. , vol.7 , pp. 671-682
    • Davis, A.C.1    Wims, M.2    Spotts, G.D.3    Hann, S.R.4    Bradley, A.5
  • 123
    • 0025763419 scopus 로고
    • Max: A helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc
    • Blackwood E. M. and Eisenman R. N. (1991) Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science 251: 1211-1217
    • (1991) Science , vol.251 , pp. 1211-1217
    • Blackwood, E.M.1    Eisenman, R.N.2
  • 125
    • 0037462459 scopus 로고    scopus 로고
    • X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors
    • Nair S. K. and Burley S. K. (2003) X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors. Cell 112: 193-205
    • (2003) Cell , vol.112 , pp. 193-205
    • Nair, S.K.1    Burley, S.K.2
  • 126
    • 0032493894 scopus 로고    scopus 로고
    • The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins
    • McMahon S. B., Van Buskirk H. A., Dugan K. A., Copeland T. D. and Cole M. D. (1998) The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94: 363-374
    • (1998) Cell , vol.94 , pp. 363-374
    • McMahon, S.B.1    Van Buskirk, H.A.2    Dugan, K.A.3    Copeland, T.D.4    Cole, M.D.5
  • 127
    • 0037194576 scopus 로고    scopus 로고
    • TIP49, but not TRRAP, modulates c-Myc and E2F1 dependent apoptosis
    • Dugan K. A., Wood M. A. and Cole M. D. (2002) TIP49, but not TRRAP, modulates c-Myc and E2F1 dependent apoptosis. Oncogene 21: 5835-5843
    • (2002) Oncogene , vol.21 , pp. 5835-5843
    • Dugan, K.A.1    Wood, M.A.2    Cole, M.D.3
  • 128
    • 0036293677 scopus 로고    scopus 로고
    • TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins
    • Nikiforov M. A., Chandriani S., Park J., Kotenko I., Matheos D., Johnsson A. et al. (2002) TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins. Mol. Cell. Biol. 22: 5054-5063
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5054-5063
    • Nikiforov, M.A.1    Chandriani, S.2    Park, J.3    Kotenko, I.4    Matheos, D.5    Johnsson, A.6
  • 129
    • 0041590889 scopus 로고    scopus 로고
    • MYC recruits the TIP60 histone acetyltransferase complex to chromatin
    • Frank S. R., Parisi T., Taubert S., Fernandez P., Fuchs M., Chan H. M. et al. (2003) MYC recruits the TIP60 histone acetyltransferase complex to chromatin. EMBO Rep. 4: 575-580
    • (2003) EMBO Rep. , vol.4 , pp. 575-580
    • Frank, S.R.1    Parisi, T.2    Taubert, S.3    Fernandez, P.4    Fuchs, M.5    Chan, H.M.6
  • 130
    • 0033859666 scopus 로고    scopus 로고
    • An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc
    • Wood M. A., McMahon S. B. and Cole M. D. (2000) An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc. Mol. Cell 5: 321-530
    • (2000) Mol. Cell , vol.5 , pp. 321-530
    • Wood, M.A.1    McMahon, S.B.2    Cole, M.D.3
  • 131
    • 0033970431 scopus 로고    scopus 로고
    • The essential cofactor TRRAP recruits the histone acetyltransferase hGCNS to c-Myc
    • McMahon S. B., Wood M. A. and Cole M. D. (2000) The essential cofactor TRRAP recruits the histone acetyltransferase hGCNS to c-Myc. Mol. Cell. Biol. 20: 556-562
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 556-562
    • McMahon, S.B.1    Wood, M.A.2    Cole, M.D.3
  • 132
    • 0035395872 scopus 로고    scopus 로고
    • The ATM-related domain of TRRAP is required for histone acetyltransferase recruitment and Myc-dependent oncogenesis
    • Park J., Kunjibettu S., McMahon S. B. and Cole M. D. (2001) The ATM-related domain of TRRAP is required for histone acetyltransferase recruitment and Myc-dependent oncogenesis. Genes Dev. 15: 1619-1624
    • (2001) Genes Dev. , vol.15 , pp. 1619-1624
    • Park, J.1    Kunjibettu, S.2    McMahon, S.B.3    Cole, M.D.4
  • 133
    • 0035882058 scopus 로고    scopus 로고
    • Deconstructing myc
    • Eisenman R. N. (2001) Deconstructing myc. Genes Dev. 15: 2023-2030
    • (2001) Genes Dev. , vol.15 , pp. 2023-2030
    • Eisenman, R.N.1
  • 134
    • 10044262126 scopus 로고    scopus 로고
    • The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60
    • Patel J. H., Du Y., Ard P. G., Phillips C., Carella B., Chen C. J. et al. (2004) The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60. Mol. Cell. Biol. 24: 10826-10834
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 10826-10834
    • Patel, J.H.1    Du, Y.2    Ard, P.G.3    Phillips, C.4    Carella, B.5    Chen, C.J.6
  • 135
    • 0036849922 scopus 로고    scopus 로고
    • Alterations of the hSNF5/INI1 gene in central nervous system atypical teratoid/rhabdoid tumors and renal and extrarenal rhabdoid tumors
    • Biegel J. A., Tan L., Zhang F., Wainwright L., Russo P. and, Rorke L. B. (2002) Alterations of the hSNF5/INI1 gene in central nervous system atypical teratoid/rhabdoid tumors and renal and extrarenal rhabdoid tumors. Clin. Cancer Res. 8: 3461-3467
    • (2002) Clin. Cancer Res. , vol.8 , pp. 3461-3467
    • Biegel, J.A.1    Tan, L.2    Zhang, F.3    Wainwright, L.4    Russo, P.5    Rorke, L.B.6
  • 136
    • 0033539932 scopus 로고    scopus 로고
    • Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors
    • DeCristofaro M. F., Betz B. L., Wang W. and Weissman B. E. (1999) Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors. Oncogene 18: 7559-7565
    • (1999) Oncogene , vol.18 , pp. 7559-7565
    • DeCristofaro, M.F.1    Betz, B.L.2    Wang, W.3    Weissman, B.E.4
  • 137
    • 0036009569 scopus 로고    scopus 로고
    • Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors
    • Uno K., Takita J., Yokomori K., Tanaka Y., Ohta S., Shimada H. et al. (2002) Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors.Genes Chromosomes Cancer 34: 33-41
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 33-41
    • Uno, K.1    Takita, J.2    Yokomori, K.3    Tanaka, Y.4    Ohta, S.5    Shimada, H.6
  • 138
    • 0035962635 scopus 로고    scopus 로고
    • When the SWI/SNF complex remodels ... the cell cycle
    • Muchardt C. and Yaniv M. (2001) When the SWI/SNF complex remodels ... the cell cycle. Oncogene 20: 3067-3075
    • (2001) Oncogene , vol.20 , pp. 3067-3075
    • Muchardt, C.1    Yaniv, M.2
  • 139
    • 10144228410 scopus 로고    scopus 로고
    • Purification and biochemical heterogeneity of the mammalian SWI-SNF complex
    • ang W., Cote J., Xue Y., Zhou S., Khavari P. ., Biggar S. . et al. (1996) Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO J. 5: 5370-5382
    • (1996) EMBO J. , vol.5 , pp. 5370-5382
    • Ang, W.1    Cote, J.2    Xue, Y.3    Zhou, S.4    Khavari, P.5    Biggar, S.6
  • 140
    • 0032963671 scopus 로고    scopus 로고
    • c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function
    • Cheng S. W., Davies K. P., Yung E., Beltran R. J., Yu J. and Kalpana G. V. (1999) c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function. Nat. Genet. 22: 102-105
    • (1999) Nat. Genet. , vol.22 , pp. 102-105
    • Cheng, S.W.1    Davies, K.P.2    Yung, E.3    Beltran, R.J.4    Yu, J.5    Kalpana, G.V.6
  • 141
    • 0042452295 scopus 로고    scopus 로고
    • Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5
    • Roberts C. W., Leroux M. M., Fleming M. D. and Orkin S. H. (2002) Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5. Cancer Cell 2: 415-425
    • (2002) Cancer Cell , vol.2 , pp. 415-425
    • Roberts, C.W.1    Leroux, M.M.2    Fleming, M.D.3    Orkin, S.H.4
  • 142
    • 0028060515 scopus 로고
    • The retinoblastema protein and BRG1 form a complex and cooperate to induce cell cycle arrest
    • Dunaief J. L., Strober B. E., Guha S., Khavari P. A., Alin K., Luban J. et al. (1994) The retinoblastema protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell 79: 119-130
    • (1994) Cell , vol.79 , pp. 119-130
    • Dunaief, J.L.1    Strober, B.E.2    Guha, S.3    Khavari, P.A.4    Alin, K.5    Luban, J.6
  • 143
    • 0035510108 scopus 로고    scopus 로고
    • Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex
    • Otsuki T., Furukawa Y., Ikeda K., Endo H., Yamashita T., Shinohara A. et al. (2001) Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex. Hum. Mol. Genet. 10: 2651-2660
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2651-2660
    • Otsuki, T.1    Furukawa, Y.2    Ikeda, K.3    Endo, H.4    Yamashita, T.5    Shinohara, A.6
  • 144
    • 1942502234 scopus 로고    scopus 로고
    • Tracing the network connecting BRCA and Fanconi anaemia proteins
    • Venkitaraman A. R. (2004) Tracing the network connecting BRCA and Fanconi anaemia proteins. Nat. Rev. Cancer 4: 266-276
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 266-276
    • Venkitaraman, A.R.1
  • 145
    • 3242887806 scopus 로고    scopus 로고
    • The interplay of Fanconi anemia proteins in the DNA damage response
    • Amst
    • Wang X. and D'Andrea A. D. (2004) The interplay of Fanconi anemia proteins in the DNA damage response. DNA Repair (Amst) 3: 1063-1069
    • (2004) DNA Repair , vol.3 , pp. 1063-1069
    • Wang, X.1    D'Andrea, A.D.2
  • 146
    • 12444257433 scopus 로고    scopus 로고
    • Fanconi anaemia proteins: Major roles in cell protection against oxidative damage
    • Pagano G. and Youssoufian H. (2003) Fanconi anaemia proteins: major roles in cell protection against oxidative damage. Bioessays 25: 589-595
    • (2003) Bioessays , vol.25 , pp. 589-595
    • Pagano, G.1    Youssoufian, H.2
  • 147
    • 6044254972 scopus 로고    scopus 로고
    • p19ARF directly and differentially controls the functions of c-Myc independently of p53
    • Qi Y., Gregory M. A., Li Z., Brousal J. P., West K. and Hann S. R. (2004) p19ARF directly and differentially controls the functions of c-Myc independently of p53. Nature 431: 712-717
    • (2004) Nature , vol.431 , pp. 712-717
    • Qi, Y.1    Gregory, M.A.2    Li, Z.3    Brousal, J.P.4    West, K.5    Hann, S.R.6
  • 148
    • 0033569422 scopus 로고    scopus 로고
    • Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
    • Eischen C. M., Weber J. D., Roussel M. F., Sherr C. J. and Cleveland J. L. (1999) Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Genes Dev. 13: 2658-2669
    • (1999) Genes Dev. , vol.13 , pp. 2658-2669
    • Eischen, C.M.1    Weber, J.D.2    Roussel, M.F.3    Sherr, C.J.4    Cleveland, J.L.5
  • 149
    • 0033569429 scopus 로고    scopus 로고
    • Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF
    • Jacobs J. J., Scheijen B., Voncken J. W., Kieboom K., Berns A. and van Lohuizen M. (1999) Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF. Genes Dev. 13: 2678-2690
    • (1999) Genes Dev. , vol.13 , pp. 2678-2690
    • Jacobs, J.J.1    Scheijen, B.2    Voncken, J.W.3    Kieboom, K.4    Berns, A.5    Van Lohuizen, M.6
  • 151
    • 2942559261 scopus 로고    scopus 로고
    • Visualization of Myc/Max/Mad family dimers and the competition for dimerization in living cells
    • Grinberg A. V., Hu C. D. and Kerppola T. K. (2004) Visualization of Myc/Max/Mad family dimers and the competition for dimerization in living cells. Mol. Cell. Biol. 24: 4294-4308
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4294-4308
    • Grinberg, A.V.1    Hu, C.D.2    Kerppola, T.K.3
  • 152
    • 0034703742 scopus 로고    scopus 로고
    • p53: Death star
    • Vousden K. H. (2000) p53: death star. Cell 103: 691-694
    • (2000) Cell , vol.103 , pp. 691-694
    • Vousden, K.H.1
  • 153
    • 0029741917 scopus 로고    scopus 로고
    • BIN1 is a novel MYC-interacting protein with features of a tumour suppressor
    • Sakamuro D., Elliott K. J., Wechsler-Reya R. and Prendergast G. C. (1996) BIN1 is a novel MYC-interacting protein with features of a tumour suppressor. Nat. Genet. 14: 69-77
    • (1996) Nat. Genet. , vol.14 , pp. 69-77
    • Sakamuro, D.1    Elliott, K.J.2    Wechsler-Reya, R.3    Prendergast, G.C.4
  • 154
    • 12244283121 scopus 로고    scopus 로고
    • Immunohistochemical analysis of Bin1/Amphiphysin II in human tissues: Diverse sites of nuclear expression and losses in prostate cancer
    • DuHadaway J. B., Lynch F. J., Brisbay S., Bueso-Ramos C., Troncoso P., McDonnell T. et al. (2003) Immunohistochemical analysis of Bin1/Amphiphysin II in human tissues: diverse sites of nuclear expression and losses in prostate cancer. J. Cell. Biochem. 88: 635-642
    • (2003) J. Cell. Biochem. , vol.88 , pp. 635-642
    • DuHadaway, J.B.1    Lynch, F.J.2    Brisbay, S.3    Bueso-Ramos, C.4    Troncoso, P.5    McDonnell, T.6
  • 155
    • 0033577992 scopus 로고    scopus 로고
    • Bin1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanisms
    • Elliott K., Sakamuro D., Basu A., Du W., Wunner W., Staller P. et al. (1999) Bin1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanisms. Oncogene 18: 3564-3573
    • (1999) Oncogene , vol.18 , pp. 3564-3573
    • Elliott, K.1    Sakamuro, D.2    Basu, A.3    Du, W.4    Wunner, W.5    Staller, P.6
  • 156
    • 0033198243 scopus 로고    scopus 로고
    • Induction of apoptosis and differentiation in neuroblastoma and astrocytoma cells by the overexpression of Bin1, a novel Myc interacting protein
    • Galderisi U., Di Bernardo G., Cipollaro M., Jori F. P., Piegari E., Cascino A. et al. (1999) Induction of apoptosis and differentiation in neuroblastoma and astrocytoma cells by the overexpression of Bin1, a novel Myc interacting protein. J. Cell. Biochem. 74: 313-322
    • (1999) J. Cell. Biochem. , vol.74 , pp. 313-322
    • Galderisi, U.1    Di Bernardo, G.2    Cipollaro, M.3    Jori, F.P.4    Piegari, E.5    Cascino, A.6
  • 157
    • 0034074925 scopus 로고    scopus 로고
    • Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma
    • Ge K., Minhas F., Duhadaway J., Mao N. C., Wilson D., Buccafusca R. et al. (2000) Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma. Int. J. Cancer. 86: 155-161
    • (2000) Int. J. Cancer. , vol.86 , pp. 155-161
    • Ge, K.1    Minhas, F.2    Duhadaway, J.3    Mao, N.C.4    Wilson, D.5    Buccafusca, R.6
  • 158
    • 0033987640 scopus 로고    scopus 로고
    • Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity
    • Ge K., Duhadaway J., Sakamuro D., Wechsler-Reya R., Reynolds C. and Prendergast G. C. (2000) Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity. Int. J. Cancer. 85: 376-383
    • (2000) Int. J. Cancer. , vol.85 , pp. 376-383
    • Ge, K.1    Duhadaway, J.2    Sakamuro, D.3    Wechsler-Reya, R.4    Reynolds, C.5    Prendergast, G.C.6
  • 159
    • 0041833704 scopus 로고    scopus 로고
    • Expression of a MYCN-interacting isoform of the tumor suppressor BIN1 is reduced in neuroblastomas with unfavorable biological features
    • Tajiri T., Liu X., Thompson P. M., Tanaka S., Suita S., Zhao H. et al. 2003) Expression of a MYCN-interacting isoform of the tumor suppressor BIN1 is reduced in neuroblastomas with unfavorable biological features. Clin. Cancer Res. 9: 3345-3355
    • (2003) Clin. Cancer Res. , vol.9 , pp. 3345-3355
    • Tajiri, T.1    Liu, X.2    Thompson, P.M.3    Tanaka, S.4    Suita, S.5    Zhao, H.6
  • 160
    • 0037979132 scopus 로고    scopus 로고
    • Targeted disruption of the murine Bin1/Amphiphysin II gene does not disable endocytosis but results in embryonic cardiomyopathy with aberrant myofibril formation
    • Muller A. J., Baker J. F., DuHadaway J. B., Ge K., Farmer G., Donover P. S. et al. (2003) Targeted disruption of the murine Bin1/Amphiphysin II gene does not disable endocytosis but results in embryonic cardiomyopathy with aberrant myofibril formation. Mol. Cell. Biol. 23: 4295-4306
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 4295-4306
    • Muller, A.J.1    Baker, J.F.2    DuHadaway, J.B.3    Ge, K.4    Farmer, G.5    Donover, P.S.6
  • 161
    • 0032905924 scopus 로고    scopus 로고
    • c-Myc target genes involved in cell growth, apoptosis, and metabolism
    • Dang C. V. (1999) c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol. Cell. Biol. 19: 1-11
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1-11
    • Dang, C.V.1
  • 162
    • 0347721764 scopus 로고    scopus 로고
    • Direct activation of RNA polymerase III transcription by c-Myc
    • Gomez-Roman N., Grandori C., Eisenman R. N. and White R. J. (2003) Direct activation of RNA polymerase III transcription by c-Myc. Nature 421: 290-294
    • (2003) Nature , vol.421 , pp. 290-294
    • Gomez-Roman, N.1    Grandori, C.2    Eisenman, R.N.3    White, R.J.4
  • 164
    • 0028847872 scopus 로고
    • The retinoblastoma susceptibility gene product regulates Myc-mediated transcription
    • Adnane J. and Robbins P. D. (1995) The retinoblastoma susceptibility gene product regulates Myc-mediated transcription. Oncogene 10: 381-387
    • (1995) Oncogene , vol.10 , pp. 381-387
    • Adnane, J.1    Robbins, P.D.2
  • 165
    • 0028307489 scopus 로고
    • Binding and suppression of the Myc transcriptional activation domain by p107
    • Gu W., Bhatia K., Magrath I. T., Dang C. V. and Dalla-Favera R. (1994) Binding and suppression of the Myc transcriptional activation domain by p107. Science 264: 251-254
    • (1994) Science , vol.264 , pp. 251-254
    • Gu, W.1    Bhatia, K.2    Magrath, I.T.3    Dang, C.V.4    Dalla-Favera, R.5
  • 167
    • 0033620609 scopus 로고    scopus 로고
    • Two MAD tails: What the recent knockouts of Mad1 and Mxi1 tell us about the MYC/MAX/MAD network
    • Foley K. P. and Eisenman R. N. (1999) Two MAD tails: what the recent knockouts of Mad1 and Mxi1 tell us about the MYC/MAX/MAD network. Biophys. Acta 1423: M37-47
    • (1999) Biophys. Acta , vol.1423
    • Foley, K.P.1    Eisenman, R.N.2
  • 168
    • 0035135759 scopus 로고    scopus 로고
    • Targeted deletion of the S-phase-specific Myc antagonist Mad3 sensitizes neuronal and lymphoid cells to radiation-induced apoptosis
    • Queva C., McArthur G. A., Iritani B. M. and Eisenman R. N. (2001) Targeted deletion of the S-phase-specific Myc antagonist Mad3 sensitizes neuronal and lymphoid cells to radiation-induced apoptosis. Mol. Cell. Biol. 21: 703-712
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 703-712
    • Queva, C.1    McArthur, G.A.2    Iritani, B.M.3    Eisenman, R.N.4
  • 169
    • 0032482421 scopus 로고    scopus 로고
    • Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth
    • Schreiber-Agus N., Meng Y., Hoang T., Hou H. Jr, Chen K., Greenberg R. et al. (1998) Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth. Nature 393: 483-187
    • (1998) Nature , vol.393 , pp. 483-1187
    • Schreiber-Agus, N.1    Meng, Y.2    Hoang, T.3    Hou Jr., H.4    Chen, K.5    Greenberg, R.6
  • 170
    • 2542536778 scopus 로고    scopus 로고
    • Loss of the Max-interacting protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects: Relevance to Miller-Dieker syndrome
    • Toyo-oka K., Hirotsune S., Gambello M. J., Zhou Z. Q., Olson L., Rosenfeld M. G. et al. (2004) Loss of the Max-interacting protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects: relevance to Miller-Dieker syndrome. Hum. Mol. Genet. 13: 1057-1067
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 1057-1067
    • Toyo-oka, K.1    Hirotsune, S.2    Gambello, M.J.3    Zhou, Z.Q.4    Olson, L.5    Rosenfeld, M.G.6
  • 171
    • 0141514041 scopus 로고    scopus 로고
    • Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis
    • Hurlin P. J., Zhou Z. Q., Toyo-oka K., Ota S., Walker W. L., Hirotsune S. et al. (2003) Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis. EMBO J. 22: 4584-4596
    • (2003) EMBO J. , vol.22 , pp. 4584-4596
    • Hurlin, P.J.1    Zhou, Z.Q.2    Toyo-oka, K.3    Ota, S.4    Walker, W.L.5    Hirotsune, S.6
  • 175
  • 176
    • 2542432915 scopus 로고    scopus 로고
    • Haploinsufficiency for tumour suppressor genes: When you don't need to go all the way
    • Santarosa M. and Ashworth A. (2004) Haploinsufficiency for tumour suppressor genes: when you don't need to go all the way. Biochim. Biophys. Acta 1654: 105-122
    • (2004) Biochim. Biophys. Acta , vol.1654 , pp. 105-122
    • Santarosa, M.1    Ashworth, A.2
  • 177
    • 8844278362 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
    • Bond G. L., Hu W., Bond E. E., Robins H., Lutzker S. G., Arva N. C. et al. (2004) A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 119: 591-602
    • (2004) Cell , vol.119 , pp. 591-602
    • Bond, G.L.1    Hu, W.2    Bond, E.E.3    Robins, H.4    Lutzker, S.G.5    Arva, N.C.6
  • 178
    • 0033551387 scopus 로고    scopus 로고
    • Mechanisms of apoptosis by c-Myc
    • Prendergast G. C. (1999) Mechanisms of apoptosis by c-Myc. Oncogene 18: 2967-2987
    • (1999) Oncogene , vol.18 , pp. 2967-2987
    • Prendergast, G.C.1
  • 180
    • 14144250455 scopus 로고    scopus 로고
    • The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma
    • USA
    • Slack A., Chen Z., Tonelli R., Pule M., Hunt L., Pession A. et al. (2005) The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma. Proc. Natl. Acad. Sci. USA 102: 731-736
    • (2005) Proc. Natl. Acad. Sci. , vol.102 , pp. 731-736
    • Slack, A.1    Chen, Z.2    Tonelli, R.3    Pule, M.4    Hunt, L.5    Pession, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.