Unmasking the S-phase-promoting potential of cyclin B1

Science

Volumn 300, Issue 5621, 2003, Pages 987-990

  Moore, Jonathan D ^a,b   Kirk, Jane A ^a   Hunt, Tim ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b RiboTargets   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; SUBSTRATES; SYNTHESIS (CHEMICAL);

CELL CYCLE;

CELLS;

CYCLIN B; CYCLIN B1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1;

BIOLOGY; DNA;

ARTICLE; CATALYSIS; CELL ACTIVITY; CELL CYCLE S PHASE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DNA REPLICATION; DNA SYNTHESIS; EUKARYOTE; MITOSIS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CDC2 PROTEIN KINASE; CDC25 PHOSPHATASE; CELL CYCLE PROTEINS; CELL EXTRACTS; CELL NUCLEUS; CHROMATIN; CYCLIN B; DNA; DNA REPLICATION; ENZYME ACTIVATION; MITOSIS; NUCLEAR ENVELOPE; NUCLEAR LOCALIZATION SIGNALS; OVUM; PROTEIN KINASES; RECOMBINANT FUSION PROTEINS; S PHASE; TRANSFECTION; XENOPUS;

ANURA; EUKARYOTA; VERTEBRATA;

EID: 0037655970     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1081418     Document Type: Article

References (32)

1. P. K. Jackson, S. Chevalier, M. Philippe, M. W. Kirschner, J. Cell Biol. 130, 755 (1995).
2. U. P. Strausfeld et al., J. Cell Sci. 109, 1555 (1996).
3. S. B. Haase, S. I. Reed, Nature 401, 394 (1999).
4. A. Amon, S. Irniger, K. Nasmyth, Cell 77, 1037 (1994).
5. D. L. Fisher, P. Nurse, EMBO J. 15, 850 (1966).
6. B. Stern, P. Nurse, Trends Genet. 12, 345 (1996).
7. M. E. Miller, F. R. Cross, J. Cell Sci. 114, 1811 (2001).
8. P. R. Clarke, D. Leiss, M. Pagano, E. Karsenti, EMBO J. 11, 1751 (1992).
9. M. J. Solomon, M. Glotzer, T. H. Lee, M. Philippe, M. W. Kirschner, Cell 63, 1013 (1990).
10. J. R. Pomerening, E. D. Sontag, J. E. Ferrell, Nature Cell Biol. 5, 346 (2003).
11. J. Pines, T. Hunter, J. Cell Biol. 115, 1 (1991).
12. J. Gautier, J. L. Maller, EMBO J. 10, 177 (1991).
13. J. Yang et al., Genes Dev. 12, 2131 (1998).
14. J. D. Moore, S. Kornbluth, T. Hunt, Mol. Biol. Cell 13, 4388 (2002).
15. Materials and methods, including details of the protocol for assaying replication and the DNA constructs used in this study, are available as supporting material on Science Online.
16. J. D. Moore, J. A. Kirk, T. Hunt, unpublished data.
17. F. Toyoshima, T. Moriguchi, A. Wada, M. Fukuda, E. Nishida, EMBO J. 17, 2728 (1998).
18. A. Hagting, C. Karlsson, P. Clute, M. Jackman, J. Pines, EMBO J. 17, 4127 (1998).
19. J. D. Moore, J. Yang, R. Truant, S. Kornbluth, J. Cell Biol. 144, 213 (1999).
20. D. Kalderon, B. L. Roberts, W. D. Richardson, A. E. Smith, Cell 39, 499 (1984).
21. P. R. Mueller, T. R. Coleman, W. G. Dunphy, Mol. Biol. Cell 6, 119 (1995).
22. P. R. Mueller, T. R. Coleman, A. Kumagai, W. G. Dunphy, Science 270, 86 (1995).
23. T. Izumi, J. L. Maller, Mol. Biol. Cell 4, 1337 (1993).
24. W. Chen, M. Wilborn, J. Rudolph, Biochemistry 39, 10781 (2000).
25. N. Furuno, N. den Elzen, J. Pines, J. Cell Biol. 147, 295 (1999).
26. A. Bueno, P. Russell, Mol. Cell. Biol. 13, 2286 (1993).
27. E. Schwob, T. Bohm, M. D. Mendenhall, K. Nasmyth, Cell 79, 233 (1994).
28. F. R. Cross, M. Yuste-Rojas, S. Gray, M. D. Jacobson, Mol. Cell 4, 11 (1999).
29. R. T. Johnson, P. N. Rao, Nature 226, 717 (1970).
30. M. E. Miller, F. R. Cross, Mol. Cell Biol. 20, 542 (2000).
31. V. M. Draviam, S. Orrechia, M. Lowe, R. Pardi, J. Pines, J. Cell Biol. 152, 945 (2001).
32. We thank J. Rudolph for the Cdc25B plasmid; J. Pines for the GST-p21N plasmid; T. Lindahl, F. Solomon, and A. Nebreda for critically reading the manuscript; and members of the Cell Cycle Control laboratory at Clare Hall for their encouragement and support during this work. We are especially grateful to H. Mahbubani for taking care of the frogs. Funded by Cancer Research UK.