The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 3, 2005, Pages 731-736

  Slack, Andrew ^a   Chen, Zaowen ^a   Tonelli, Roberto ^b   Pule, Martin ^a   Hunt, Lisa ^a   Pession, Andrea ^b   Shohet, Jason M ^a  

^a CENTER FOR CELL AND GENE THERAPY   (United States)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Apoptosis pediatric cancer; Chromatin immunoprecipitation; Oncogene; Transactivation

Indexed keywords

LUCIFERASE; MYC PROTEIN; PROTEIN MDM2; PROTEIN P53;

APOPTOSIS; ARTICLE; CELL CYCLE; CONTROLLED STUDY; E BOX ELEMENT; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NEUROBLASTOMA CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; TRANSACTIVATION; WESTERN BLOTTING;

APOPTOSIS; CELL LINE, TUMOR; E-BOX ELEMENTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEUROBLASTOMA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 14144250455     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0405495102     Document Type: Article

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