Immunohistochemical analysis of Bin1/Amphiphysin II in human tissues: Diverse sites of nuclear expression and losses in prostate cancer

Journal of Cellular Biochemistry

Volumn 88, Issue 3, 2003, Pages 635-642

  DuHadaway, James B ^a   Lynch, Frank J ^b   Brisbay, Shawn ^c   Bueso Ramos, Carlos ^c   Troncoso, Patricia ^c   McDonnell, Timothy ^c   Prendergast, George C ^a,d  

^a LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b QualTek Molecular Laboratories   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Amphiphysin; Apoptosis; BAR adapter proteins; Bin2; Bin3; Cancer; Differentiation; E1A; Heart; Macrophage; Muscle; Myc; Myoblast; Programmed cell death; Rvs161; Rvs167; Signal transduction; Transformation

Indexed keywords

AMPHIPHYSIN; AMPHIPHYSIN II; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA SPLICING; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STAINING; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; CELL NUCLEUS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; NERVE TISSUE PROTEINS; PROSTATIC NEOPLASMS; PROTEIN ISOFORMS; TISSUE DISTRIBUTION;

EID: 12244283121     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10380     Document Type: Article

References (20)

1. Butler MH, David C, Ochoa G-C, Freyberg Z, Daniell L, Grabs D, Cremona O, De Camilli P. 1997. Amphiphysin II (SH3P9; BIN1), a member of the amphiphysin/RVS family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of Ravier in brain and around T tubules in skeletal muscle. J Cell Biol 137:1355-1367.
2. David C, McPherson PS, Mundigl O, de Camilli P. 1996. A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals. Proc Natl Acad Sci USA 93:331-335.
3. DuHadaway JB, Sakamuro D, Ewert DL, Prendergast GC. 2001. Bin1 mediates apoptosis by c-Myc in transformed primary cells. Cancer Res 16:3151-3156.
4. Elliott K, Sakamuro D, Basu A, Du W, Wunner W, Staller P, Gaubatz S, Zhang H, Prochownik E, Eilers M, Prendergast GC. 1999. Bin1 functionally interacts with Myc in cells and inhibits cell proliferation by multiple mechanisms. Oncogene 18:3564-3573.
5. Elliott K, Ge K, Du W, Prendergast GC. 2000. The c-Mycinteracting adapter protein Bin1 activates a caspaseindependent cell death program. Oncogene 19:4669-4684.
6. Ge K, DuHadaway J, Du W, Herlyn M, Rodeck U, Prendergast GC. 1999. Mechanism for elimination of a tumor suppressor: Aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma. Proc Natl Acad Sci USA 96:9689-9694.
7. Ge K, DuHadaway J, Sakamuro D, Wechsler-Reya R, Reynolds C, Prendergast GC. 2000a. Losses of the tumor suppressor Bin1 in breast carcinoma are frequent and reflect deficits in a programmed cell death capacity. Int J Cancer 85:376-383.
8. Ge K, Minhas F, DuHadaway J, Mao N-C, Wilson D, Sakamuro D, Buccafusca R, Nelson P, Malkowicz SB, Tomaszewski JT, Prendergast GC. 2000b. Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma. Int J Cancer 86:155-161.
9. Kadlec L, Pendergast A-M. 1997. The amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulation. Proc Natl Acad Sci USA 94:12390-12395.
10. Koprowski H, Steplewski Z, Mitchell K, Herlyn M, Herlyn D, Fuhrer P. 1979. Colorectal carcinoma antigens detected by hybridoma antibodies. Somatic Cell Genet 5:957-972.
11. Lichte B, Veh RW, Meyer HE, Kilimann MW. 1992. Amphiphysin, a novel protein associated with synaptic vesicles. EMBO J 11:2521-2530.
12. Ramjaun AR, McPherson PS. 1998. Multiple amphiphysin II splice variants display differential clathrin binding: Identification of two distinct clathrin-binding sites. J Neurochem 70:2369-2376.
13. Ramjaun AR, Micheva KD, Bouchelet I, McPherson PS. 1997. Identification and characterization of a nerve terminal-enriched amphiphysin isoform. J Biol Chem 272:16700-16706.
14. Routhier EL, Donover PS, Prendergast GC. In press hobl+, the homolog of Bin1/Amphiphysin II in fission yeast, is dispensable for endocytosis but required for starvation or genotoxic stress. Oncogene.
15. Sakamuro D, Elliott K, Wechsler-Reya R, Prendergast GC. 1996. BIN1 is a novel MYC-interacting protein with features of a tumor suppressor. Nat Genet 14:69-77.
16. Tsutsui K, Maeda Y, Tsutsui K, Seki S, Tokunaga A. 1997. cDNA cloning of a novel amphiphysin isoform and tissuespecific expression of its multiple splice variants. Biochem Biophys Res Comm 236:178-183.
17. Wechsler-Reya R, Elliott K, Herlyn M, Prendergast GC. 1997a. The putative tumor suppressor BIN1 is a shortlived nuclear phosphoprotein whose localization is altered in malignant cells. Cancer Res 57:3258-3263.
18. Wechsler-Reya R, Sakamuro D, Zhang J, Duhadaway J, Prendergast GC. 1997b. Structural analysis of the human BIN1 gene: Evidence for tissue-specific transcriptional regulation and alternate RNA splicing. J Biol Chem 272:31453-31458.
19. Wechsler-Reya R, Elliott K, Prendergast GC. 1998. A role for the putative tumor suppressor Bin1 in muscle cell differentiation. Mol Cell Biol 18:566-575.
20. Wigge P, Kohler K, Vallis Y, Doyle CA, Owen D, Hunt SP, McMahon HT. 1997. Amphiphysin heterodimers: Potential role in clathrin-mediated endocytosis. Mol Biol Cell 8:2003-2015.