-
1
-
-
0035171545
-
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
-
Derbinski J, Schulte A, Kyewski B, Klein L: Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat Immunol 2001;2:1032-1039.
-
(2001)
Nat Immunol
, vol.2
, pp. 1032-1039
-
-
Derbinski, J.1
Schulte, A.2
Kyewski, B.3
Klein, L.4
-
2
-
-
0027517545
-
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
-
Powrie F, Leach MW, Mauze S, Caddle LB, Coffman RL: Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. Int Immunol 1993; 5:1461-1471.
-
(1993)
Int Immunol
, vol.5
, pp. 1461-1471
-
-
Powrie, F.1
Leach, M.W.2
Mauze, S.3
Caddle, L.B.4
Coffman, R.L.5
-
3
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M: Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-1164.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
5
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
Takahashi T, Kuniyasu Y, Toda M, Sakaguchi N, Itoh M, Iwata M, Shimizu J, Sakaguchi S: Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 1998;10:1969-1980.
-
(1998)
Int Immunol
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
Sakaguchi, N.4
Itoh, M.5
Iwata, M.6
Shimizu, J.7
Sakaguchi, S.8
-
6
-
-
0033985780
-
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
-
Thornton AM, Shevach EM: Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol 2000;164: 183-190.
-
(2000)
J Immunol
, vol.164
, pp. 183-190
-
-
Thornton, A.M.1
Shevach, E.M.2
-
7
-
-
1642331576
-
Immune regulation by self-reactive T cells is antigen specific
-
Tanchot C, Vasseur F, Pontoux C, Garcia C, Sarukhan A: Immune regulation by self-reactive T cells is antigen specific. J Immunol 2004;172:4285-4291.
-
(2004)
J Immunol
, vol.172
, pp. 4285-4291
-
-
Tanchot, C.1
Vasseur, F.2
Pontoux, C.3
Garcia, C.4
Sarukhan, A.5
-
8
-
-
23844455192
-
Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice
-
Masteller EL, Warner MR, Tang Q, Tarbell KV, McDevitt H, Bluestone JA: Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice. J Immunol 2005;175:3053-3059.
-
(2005)
J Immunol
, vol.175
, pp. 3053-3059
-
-
Masteller, E.L.1
Warner, M.R.2
Tang, Q.3
Tarbell, K.V.4
McDevitt, H.5
Bluestone, J.A.6
-
9
-
-
12744262844
-
Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes
-
Jaeckel E, von Boehmer H, Manns MP: Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes. Diabetes 2005;54:306-310.
-
(2005)
Diabetes
, vol.54
, pp. 306-310
-
-
Jaeckel, E.1
Von Boehmer, H.2
Manns, M.P.3
-
10
-
-
0043244867
-
Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo
-
Walker LS, Chodos A, Eggena M, Dooms H, Abbas AK: Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J Exp Med 2003;198:249-258.
-
(2003)
J Exp Med
, vol.198
, pp. 249-258
-
-
Walker, L.S.1
Chodos, A.2
Eggena, M.3
Dooms, H.4
Abbas, A.K.5
-
11
-
-
0041806547
-
In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro
-
U S A
-
Klein L, Khazaie K, von Boehmer H: In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro. Proc Natl Acad Sci U S A 2003;100:8886-8891.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 8886-8891
-
-
Klein, L.1
Khazaie, K.2
Von Boehmer, H.3
-
12
-
-
0036144888
-
Homeostasis and anergy of CD4(+) CD25(+) suppressor T cells in vivo
-
Gavin MA, Clarke SR, Negrou E, Gallegos A, Rudensky A: Homeostasis and anergy of CD4(+) CD25(+) suppressor T cells in vivo. Nat Immunol 2002;3:33-41.
-
(2002)
Nat Immunol
, vol.3
, pp. 33-41
-
-
Gavin, M.A.1
Clarke, S.R.2
Negrou, E.3
Gallegos, A.4
Rudensky, A.5
-
13
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton AM, Shevach EM: CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998;188:287-296.
-
(1998)
J Exp Med
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
14
-
-
0035806244
-
Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
-
Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G: Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med 2001;193:1303-1310.
-
(2001)
J Exp Med
, vol.193
, pp. 1303-1310
-
-
Dieckmann, D.1
Plottner, H.2
Berchtold, S.3
Berger, T.4
Schuler, G.5
-
15
-
-
0035421654
-
Cutting edge: Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
-
Piccirillo CA, Shevach EM: Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J Immunol 2001;167:1137-1140.
-
(2001)
J Immunol
, vol.167
, pp. 1137-1140
-
-
Piccirillo, C.A.1
Shevach, E.M.2
-
16
-
-
18644366689
-
License to heal: Bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC
-
Vlad G, Cortesini R, Suciu-Foca N: License to heal: bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC. J Immunol 2005; 174:5907-5914.
-
(2005)
J Immunol
, vol.174
, pp. 5907-5914
-
-
Vlad, G.1
Cortesini, R.2
Suciu-Foca, N.3
-
17
-
-
1842581857
-
Cutting Edge: Human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells
-
Misra N, Bayry J, Lacroix-Desmazes S, Kazatchkine MD, Kaveri SV: Cutting Edge: Human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells. J Immunol 2004;172:4676-4680.
-
(2004)
J Immunol
, vol.172
, pp. 4676-4680
-
-
Misra, N.1
Bayry, J.2
Lacroix-Desmazes, S.3
Kazatchkine, M.D.4
Kaveri, S.V.5
-
18
-
-
0346119234
-
Modulation of tryptophan catabolism by regulatory T cells
-
Fallarino F, Grohmann U, Hwang KW, Orabona C, Vacca C, Bianchi R, Belladonna ML, Fioretti MC, Alegre ML, Puccetti P: Modulation of tryptophan catabolism by regulatory T cells. Nat Immunol 2003;4:1206-1212.
-
(2003)
Nat Immunol
, vol.4
, pp. 1206-1212
-
-
Fallarino, F.1
Grohmann, U.2
Hwang, K.W.3
Orabona, C.4
Vacca, C.5
Bianchi, R.6
Belladonna, M.L.7
Fioretti, M.C.8
Alegre, M.L.9
Puccetti, P.10
-
19
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan MS, Boesteanu A, Reed AJ, Petrone AL, Holenbeck AE, Lerman MA, Naji A, Caton AJ: Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001;2:301-306.
-
(2001)
Nat Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
Boesteanu, A.2
Reed, A.J.3
Petrone, A.L.4
Holenbeck, A.E.5
Lerman, M.A.6
Naji, A.7
Caton, A.J.8
-
20
-
-
1542368420
-
Development and function of CD25+CD4+ regulatory T cells
-
Fehervari Z, Sakaguchi S: Development and function of CD25+CD4+ regulatory T cells. Curr Opin Immunol 2004;16:203-208.
-
(2004)
Curr Opin Immunol
, vol.16
, pp. 203-208
-
-
Fehervari, Z.1
Sakaguchi, S.2
-
21
-
-
0028102655
-
High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice
-
Lafaille JJ, Nagashima K, Katsuki M, Tonegawa S: High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell 1994;78:399-408.
-
(1994)
Cell
, vol.78
, pp. 399-408
-
-
Lafaille, J.J.1
Nagashima, K.2
Katsuki, M.3
Tonegawa, S.4
-
22
-
-
2642654250
-
Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities
-
Luhder F, Katz J, Benoist C, Mathis D: Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities. J Exp Med 1998;187:379-387.
-
(1998)
J Exp Med
, vol.187
, pp. 379-387
-
-
Luhder, F.1
Katz, J.2
Benoist, C.3
Mathis, D.4
-
23
-
-
0033136302
-
Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
-
Itoh M, Takahashi T, Sakaguchi N, Kuniyasu Y, Shimizu J, Otsuka F, Sakaguchi S: Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol 1999;162:5317-5326.
-
(1999)
J Immunol
, vol.162
, pp. 5317-5326
-
-
Itoh, M.1
Takahashi, T.2
Sakaguchi, N.3
Kuniyasu, Y.4
Shimizu, J.5
Otsuka, F.6
Sakaguchi, S.7
-
24
-
-
4143066714
-
Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors
-
Hsieh CS, Liang Y, Tyznik AJ, Self SG, Liggitt D, Rudensky AY: Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors. Immunity 2004;21:267-277.
-
(2004)
Immunity
, vol.21
, pp. 267-277
-
-
Hsieh, C.S.1
Liang, Y.2
Tyznik, A.J.3
Self, S.G.4
Liggitt, D.5
Rudensky, A.Y.6
-
25
-
-
22044447704
-
TCR alpha beta repertoire diversity of human naturally occurring CD4+CD25+ regulatory T cells
-
Fujishima M, Hirokawa M, Fujishima N, Sawada K: TCR alpha beta repertoire diversity of human naturally occurring CD4+CD25+ regulatory T cells. Immunol Lett 2005;99:193-197.
-
(2005)
Immunol Lett
, vol.99
, pp. 193-197
-
-
Fujishima, M.1
Hirokawa, M.2
Fujishima, N.3
Sawada, K.4
-
26
-
-
2242423605
-
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
-
Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL: CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 2002;420:502-507.
-
(2002)
Nature
, vol.420
, pp. 502-507
-
-
Belkaid, Y.1
Piccirillo, C.A.2
Mendez, S.3
Shevach, E.M.4
Sacks, D.L.5
-
28
-
-
0028171297
-
CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse
-
Blair PJ, Bultman SJ, Haas JC, Rouse BT, Wilkinson JE, Godfrey VL: CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse. J Immunol 1994;153:3764-3774.
-
(1994)
J Immunol
, vol.153
, pp. 3764-3774
-
-
Blair, P.J.1
Bultman, S.J.2
Haas, J.C.3
Rouse, B.T.4
Wilkinson, J.E.5
Godfrey, V.L.6
-
29
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila TA, Blaeser F, Ho N, Lederman HM, Voulgaropoulos C, Helms C, Bowcock AM: JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J Clin Invest 2000;106:R75-R81.
-
(2000)
J Clin Invest
, vol.106
-
-
Chatila, T.A.1
Blaeser, F.2
Ho, N.3
Lederman, H.M.4
Voulgaropoulos, C.5
Helms, C.6
Bowcock, A.M.7
-
30
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett CL, Christie J, Ramsdell F, Brunkow ME, Ferguson PJ, Whitesell L, Kelly TE, Saulsbury FT, Chance PF, Ochs HD: The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001;27:20-21.
-
(2001)
Nat Genet
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
Brunkow, M.E.4
Ferguson, P.J.5
Whitesell, L.6
Kelly, T.E.7
Saulsbury, F.T.8
Chance, P.F.9
Ochs, H.D.10
-
31
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin RS, Ramsdell F, Peake J, Faravelli F, Casanova JL, Buist N, Levy-Lahad E, Mazzella M, Goulet O, Perroni L, Bricarelli FD, Byrne G, McEuen M, Proll S, Appleby M, Brunkow ME: X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001;27:18-20.
-
(2001)
Nat Genet
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
Faravelli, F.4
Casanova, J.L.5
Buist, N.6
Levy-Lahad, E.7
Mazzella, M.8
Goulet, O.9
Perroni, L.10
Bricarelli, F.D.11
Byrne, G.12
McEuen, M.13
Proll, S.14
Appleby, M.15
Brunkow, M.E.16
-
32
-
-
0346888498
-
Control of autoimmunity by naturally arising regulatory CD4+ T cells
-
Hori S, Takahashi T, Sakaguchi S: Control of autoimmunity by naturally arising regulatory CD4+ T cells. Adv Immunol 2003;81:331-371.
-
(2003)
Adv Immunol
, vol.81
, pp. 331-371
-
-
Hori, S.1
Takahashi, T.2
Sakaguchi, S.3
-
33
-
-
0037385330
-
Foxp3 programs the development and function of CD4+ CD25+ regulatory T cells
-
Fontenot JD, Gavin MA, Rudensky AY: Foxp3 programs the development and function of CD4+ CD25+ regulatory T cells. Nat Immunol 2003;4: 330-336.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
34
-
-
27144472258
-
In vitro-generated regulatory T cells induced by Foxp3-retrovirus infection control murine contact allergy and systemic autoimmunity
-
Loser K, Hansen W, Apelt J, Balkow S, Buer J, Beissert S: In vitro-generated regulatory T cells induced by Foxp3-retrovirus infection control murine contact allergy and systemic autoimmunity. Gene Ther 2005;12:1294-1304.
-
(2005)
Gene Ther
, vol.12
, pp. 1294-1304
-
-
Loser, K.1
Hansen, W.2
Apelt, J.3
Balkow, S.4
Buer, J.5
Beissert, S.6
-
35
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY: Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005;22:329-341.
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
36
-
-
24144480562
-
Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus
-
Watanabe N, Wang YH, Lee HK, Ito T, Wang YH, Cao W, Liu YJ: Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus. Nature 2005;436:1181-1185.
-
(2005)
Nature
, vol.436
, pp. 1181-1185
-
-
Watanabe, N.1
Wang, Y.H.2
Lee, H.K.3
Ito, T.4
Wang, Y.H.5
Cao, W.6
Liu, Y.J.7
-
37
-
-
17044430217
-
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
-
U S A
-
Wan YY, Flavell RA: Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc Natl Acad Sci U S A 2005;102:5126-5131.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 5126-5131
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
38
-
-
0035813231
-
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation
-
Schubert LA, Jeffrey E, Zhang Y, Ramsdell F, Ziegler SF: Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J Biol Chem 2001;276:37672-37679.
-
(2001)
J Biol Chem
, vol.276
, pp. 37672-37679
-
-
Schubert, L.A.1
Jeffrey, E.2
Zhang, Y.3
Ramsdell, F.4
Ziegler, S.F.5
-
39
-
-
17044393922
-
Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells
-
U S A
-
Bettelli E, Dastrange M, Oukka M: Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A 2005;102:5138-5143.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 5138-5143
-
-
Bettelli, E.1
Dastrange, M.2
Oukka, M.3
-
40
-
-
0037099613
-
CD4 (+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
-
Piccirillo CA, Letterio JJ, Thornton AM, McHugh RS, Mamura M, Mizuhara H, Shevach EM: CD4 (+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J Exp Med 2002;196:237-246.
-
(2002)
J Exp Med
, vol.196
, pp. 237-246
-
-
Piccirillo, C.A.1
Letterio, J.J.2
Thornton, A.M.3
McHugh, R.S.4
Mamura, M.5
Mizuhara, H.6
Shevach, E.M.7
-
41
-
-
0034967640
-
Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells
-
Suri-Payer E, Cantor H: Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J Autoimmun 2001;16:115-123.
-
(2001)
J Autoimmun
, vol.16
, pp. 115-123
-
-
Suri-Payer, E.1
Cantor, H.2
-
42
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W: Interleukin-10- deficient mice develop chronic enterocolitis. Cell 1993;75:263-274.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
43
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F: An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 1999;190:995-1004.
-
(1999)
J Exp Med
, vol.190
, pp. 995-1004
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
44
-
-
1842480959
-
TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes
-
U S A
-
Peng Y, Laouar Y, Li MO, Green EA, Flavell RA: TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes. Proc Natl Acad Sci U S A 2004;101:4572-4577.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 4572-4577
-
-
Peng, Y.1
Laouar, Y.2
Li, M.O.3
Green, E.A.4
Flavell, R.A.5
-
45
-
-
0035801335
-
Cell contact-dependent immunosuppression by CD4(+)CD25 (+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
Nakamura K, Kitani A, Strober W: Cell contact-dependent immunosuppression by CD4(+)CD25 (+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med 2001; 194:629-644.
-
(2001)
J Exp Med
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
46
-
-
0037379654
-
TGF-beta: The missing link in CD4+CD25+ regulatory T cell-mediated immunosuppression
-
Chen W, Wahl SM: TGF-beta: the missing link in CD4+CD25+ regulatory T cell-mediated immunosuppression. Cytokine Growth Factor Rev 2003;14: 85-89.
-
(2003)
Cytokine Growth Factor Rev
, vol.14
, pp. 85-89
-
-
Chen, W.1
Wahl, S.M.2
-
47
-
-
0037987977
-
Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
-
Wakkach A, Fournier N, Brun V, Breittmayer JP, Cottrez F, Groux H: Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 2003;18:605-617.
-
(2003)
Immunity
, vol.18
, pp. 605-617
-
-
Wakkach, A.1
Fournier, N.2
Brun, V.3
Breittmayer, J.P.4
Cottrez, F.5
Groux, H.6
-
48
-
-
2442432505
-
Mechanisms of tolerance induced by TGF beta-treated APC: CD4 regulatory T cells prevent the induction of the immune response possibly through a mechanism involving TGF beta
-
Alard P, Clark SL, Kosiewicz MM: Mechanisms of tolerance induced by TGF beta-treated APC: CD4 regulatory T cells prevent the induction of the immune response possibly through a mechanism involving TGF beta. Eur J Immunol 2004;34:1021-1030.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1021-1030
-
-
Alard, P.1
Clark, S.L.2
Kosiewicz, M.M.3
-
49
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, de Vries JE, Roncarolo MG: A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997;389:737-742.
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
De Vries, J.E.6
Roncarolo, M.G.7
-
50
-
-
0035399985
-
Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
-
Thorstenson KM, Khoruts A: Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J Immunol 2001;167:188-195.
-
(2001)
J Immunol
, vol.167
, pp. 188-195
-
-
Thorstenson, K.M.1
Khoruts, A.2
-
51
-
-
0037099733
-
Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells
-
corrected
-
Dieckmann D, Bruett CH, Ploettner H, Lutz MB, Schuler G: Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. J Exp Med 2002;196: 247-253.
-
(2002)
J Exp Med
, vol.196
, pp. 247-253
-
-
Dieckmann, D.1
Bruett, C.H.2
Ploettner, H.3
Lutz, M.B.4
Schuler, G.5
-
52
-
-
0035876913
-
A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood
-
Yamagiwa S, Gray JD, Hashimoto S, Horwitz DA: A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood. J Immunol 2001;166: 7282-7289.
-
(2001)
J Immunol
, vol.166
, pp. 7282-7289
-
-
Yamagiwa, S.1
Gray, J.D.2
Hashimoto, S.3
Horwitz, D.A.4
-
54
-
-
0035901597
-
Fingerprints of anergjc T cells
-
Lechner O, Lauber J, Franzke A, Sarukhan A, von Boehmer H, Euer J: Fingerprints of anergjc T cells. Curr Biol 2001;11:587-595.
-
(2001)
Curr Biol
, vol.11
, pp. 587-595
-
-
Lechner, O.1
Lauber, J.2
Franzke, A.3
Sarukhan, A.4
Von Boehmer, H.5
Euer, J.6
-
55
-
-
0036195161
-
CD4 (+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
McHugh RS, Whitters MJ, Piccirillo CA, Young DA, Shevach EM, Collins M, Byrne MC: CD4 (+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 2002;16:311-323.
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.S.1
Whitters, M.J.2
Piccirillo, C.A.3
Young, D.A.4
Shevach, E.M.5
Collins, M.6
Byrne, M.C.7
-
56
-
-
19444383208
-
Frontline: Neuropilin-1: A surface marker of regulatory T cells
-
Vol. 34(3) 2004, pp 623-630, DOI 10,1002/eji.200324799
-
Bruder D, Probst-Kepper M, Westendorf AM, Geffers R, Beissert S, Loser K, von Boehmer H, Buer J, Hansen W: Frontline: Neuropilin-1: a surface marker of regulatory T cells (Vol. 34(3) 2004, pp 623-630, DOI 10,1002/eji.200324799). Eur J Immunol 2004;34:1498.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1498
-
-
Bruder, D.1
Probst-Kepper, M.2
Westendorf, A.M.3
Geffers, R.4
Beissert, S.5
Loser, K.6
Von Boehmer, H.7
Buer, J.8
Hansen, W.9
-
57
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri R, Cox T, Yasayko SA, Ramsdell F: An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 2003;4:337-342.
-
(2003)
Nat Immunol
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
58
-
-
20844432429
-
Analysis of FOXP3 protein expression in human CD4(+)CD25(+) regulatory T cells at the single-cell level
-
Roncador G, Brown PJ, Maestre L, Hue S, Martinez-Torrecuadrada JL, Ling KL, Pratap S, Toms C, Fox BC, Cerundolo V, Powrie F, Banham AH: Analysis of FOXP3 protein expression in human CD4(+)CD25(+) regulatory T cells at the single-cell level. Eur J Immunol 2005;35:1681-1691.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1681-1691
-
-
Roncador, G.1
Brown, P.J.2
Maestre, L.3
Hue, S.4
Martinez-Torrecuadrada, J.L.5
Ling, K.L.6
Pratap, S.7
Toms, C.8
Fox, B.C.9
Cerundolo, V.10
Powrie, F.11
Banham, A.H.12
-
59
-
-
20844449950
-
New tools to identify regulatory T cells
-
Graca L: New tools to identify regulatory T cells. Eur J Immunol 2005;35:1678-1680.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1678-1680
-
-
Graca, L.1
-
60
-
-
0036170938
-
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
-
Shimizu J, Yamazaki S, Takahashi T, Ishida Y, Sakaguchi S: Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol 2002;3:135-142.
-
(2002)
Nat Immunol
, vol.3
, pp. 135-142
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
61
-
-
0030962132
-
A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis
-
U S A
-
Nocentini G, Giunchi L, Ronchetti S, Krausz LT, Bartoli A, Moraca R, Migliorati G, Riccardi C: A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis. Proc Natl Acad Sci U S A 1997;94:6216-6221.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 6216-6221
-
-
Nocentini, G.1
Giunchi, L.2
Ronchetti, S.3
Krausz, L.T.4
Bartoli, A.5
Moraca, R.6
Migliorati, G.7
Riccardi, C.8
-
62
-
-
0038106763
-
Regulation of murine inflammatory bowel disease by CD25+ and CD25-CD4+ glucocorticoid-induced TNF receptor family-related gene+ regulatory T cells
-
Uraushihara K, Kanai T, Ko K, Totsuka T, Makita S, Iiyama R, Nakamura T, Watanabe M: Regulation of murine inflammatory bowel disease by CD25+ and CD25-CD4+ glucocorticoid-induced TNF receptor family-related gene+ regulatory T cells. J Immunol 2003;171:708-716.
-
(2003)
J Immunol
, vol.171
, pp. 708-716
-
-
Uraushihara, K.1
Kanai, T.2
Ko, K.3
Totsuka, T.4
Makita, S.5
Iiyama, R.6
Nakamura, T.7
Watanabe, M.8
-
64
-
-
2442429448
-
Cutting edge: The natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression
-
Ji HB, Liao G, Faubion WA, Abadia-Molina AC, Cozzo C, Laroux FS, Caton A, Terhorst C: Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression. J Immunol 2004;172:5823-5827.
-
(2004)
J Immunol
, vol.172
, pp. 5823-5827
-
-
Ji, H.B.1
Liao, G.2
Faubion, W.A.3
Abadia-Molina, A.C.4
Cozzo, C.5
Laroux, F.S.6
Caton, A.7
Terhorst, C.8
-
65
-
-
1842424807
-
Cutting Edge: Ligation of the glucocorticoid-induced TNF receptor enhances autoreactive CD4+ T cell activation and experimental autoimmune encephalomyelitis
-
Kohm AP, Williams JS, Miller SD: Cutting Edge: Ligation of the glucocorticoid-induced TNF receptor enhances autoreactive CD4+ T cell activation and experimental autoimmune encephalomyelitis. J Immunol 2004;172:4686-4690.
-
(2004)
J Immunol
, vol.172
, pp. 4686-4690
-
-
Kohm, A.P.1
Williams, J.S.2
Miller, S.D.3
-
66
-
-
0028484545
-
CTLA-4 can function as a negative regulator of T cell activation
-
Walunas TL, Lenschow DJ, Bakker CY, Linsley PS, Freeman GJ, Green JM, Thompson CB, Bluestone JA: CTLA-4 can function as a negative regulator of T cell activation. Immunity 1994;1:405-413.
-
(1994)
Immunity
, vol.1
, pp. 405-413
-
-
Walunas, T.L.1
Lenschow, D.J.2
Bakker, C.Y.3
Linsley, P.S.4
Freeman, G.J.5
Green, J.M.6
Thompson, C.B.7
Bluestone, J.A.8
-
67
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+) CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
Takahashi T, Tagami T, Yamazaki S, Uede T, Shimizu J, Sakaguchi N, Mak TW, Sakaguchi S: Immunologic self-tolerance maintained by CD25(+) CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 2000;192:303-310.
-
(2000)
J Exp Med
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
Mak, T.W.7
Sakaguchi, S.8
-
68
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read S, Malmstrom V, Powrie F: Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med 2000;192:295-302.
-
(2000)
J Exp Med
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
69
-
-
0344299189
-
Cutting edge: Lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous
-
Bachmann MF, Kohler G, Ecabert B, Mak TW, Kopf M: Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous. J Immunol 1999;163:1128-1131.
-
(1999)
J Immunol
, vol.163
, pp. 1128-1131
-
-
Bachmann, M.F.1
Kohler, G.2
Ecabert, B.3
Mak, T.W.4
Kopf, M.5
-
70
-
-
0035056017
-
CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy
-
Chambers CA, Kuhns MS, Egen JG, Allison JP: CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy. Annu Rev Immunol 2001;19:565-594.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 565-594
-
-
Chambers, C.A.1
Kuhns, M.S.2
Egen, J.G.3
Allison, J.P.4
-
71
-
-
17644376164
-
CD25(+)CD4(+) regulatory T cells exert in vitro suppressive activity independent of CTLA-4
-
Kataoka H, Takahashi S, Takase K, Yamasaki S, Yokosuka T, Koike T, Saito T: CD25(+)CD4(+) regulatory T cells exert in vitro suppressive activity independent of CTLA-4. Int Immunol 2005;17:421-427.
-
(2005)
Int Immunol
, vol.17
, pp. 421-427
-
-
Kataoka, H.1
Takahashi, S.2
Takase, K.3
Yamasaki, S.4
Yokosuka, T.5
Koike, T.6
Saito, T.7
-
72
-
-
0027324601
-
Integrin alpha e beta 7 mediates adhesion of T lymphocytes to epithelial cells
-
Cepek KL, Parker CM, Madara JL, Brenner MB: Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells. J Immunol 1993;150: 3459-3470.
-
(1993)
J Immunol
, vol.150
, pp. 3459-3470
-
-
Cepek, K.L.1
Parker, C.M.2
Madara, J.L.3
Brenner, M.B.4
-
73
-
-
0034544449
-
Cutaneous inflammatory disorder in integrin alphaE (CD103)-deficient mice
-
Schon MP, Schon M, Warren HB, Donohue JP, Parker CM: Cutaneous inflammatory disorder in integrin alphaE (CD103)-deficient mice. J Immunol 2000;165:6583-6589.
-
(2000)
J Immunol
, vol.165
, pp. 6583-6589
-
-
Schon, M.P.1
Schon, M.2
Warren, H.B.3
Donohue, J.P.4
Parker, C.M.5
-
74
-
-
0036791004
-
Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as
-
U S A
-
Lehmann J, Huehn J, de la Rosa M, Maszyna F, Kretschmer U, Krenn V, Brunner M, Scheffold A, Hamann A: Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as. Proc Natl Acad Sci U S A 2002;99:13031-13036.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 13031-13036
-
-
Lehmann, J.1
Huehn, J.2
De La Rosa, M.3
Maszyna, F.4
Kretschmer, U.5
Krenn, V.6
Brunner, M.7
Scheffold, A.8
Hamann, A.9
-
75
-
-
0141762495
-
A unique subpopulation of CD4+ regulatory T cells controls wasting disease, IL-10 secretion and T cell homeostasis
-
Banz A, Peixoto A, Pontoux C, Cordier C, Rocha B, Papiernik M: A unique subpopulation of CD4+ regulatory T cells controls wasting disease, IL-10 secretion and T cell homeostasis. Eur J Immunol 2003;33:2419-2428.
-
(2003)
Eur J Immunol
, vol.33
, pp. 2419-2428
-
-
Banz, A.1
Peixoto, A.2
Pontoux, C.3
Cordier, C.4
Rocha, B.5
Papiernik, M.6
-
76
-
-
10744221289
-
Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells
-
Huehn J, Siegmund K, Lehmann JC, Siewert C, Haubold U, Feuerer M, Debes GF, Lauber J, Frey O, Przybylski GK, Niesner,U, de la Rosa M, Schmidt CA, Brauer R, Buer J, Scheffold A, Hamann A: Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells. J Exp Med 2004;199: 303-313.
-
(2004)
J Exp Med
, vol.199
, pp. 303-313
-
-
Huehn, J.1
Siegmund, K.2
Lehmann, J.C.3
Siewert, C.4
Haubold, U.5
Feuerer, M.6
Debes, G.F.7
Lauber, J.8
Frey, O.9
Przybylski, G.K.10
Niesner, U.11
De La Rosa, M.12
Schmidt, C.A.13
Brauer, R.14
Buer, J.15
Scheffold, A.16
Hamann, A.17
-
77
-
-
0036139515
-
The neuropilins: Multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis
-
Neufeld G, Cohen T, Shraga N, Lange T, Kessler O, Herzog Y: The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis. Trends Cardiovasc Med 2002;12:13-19.
-
(2002)
Trends Cardiovasc Med
, vol.12
, pp. 13-19
-
-
Neufeld, G.1
Cohen, T.2
Shraga, N.3
Lange, T.4
Kessler, O.5
Herzog, Y.6
-
78
-
-
0035369125
-
Physiological regulation of the immunological synapse by agrin
-
Khan AA, Bose C, Yam LS, Soloski MJ, Rupp F: Physiological regulation of the immunological synapse by agrin. Science 2001;292:1681-1686.
-
(2001)
Science
, vol.292
, pp. 1681-1686
-
-
Khan, A.A.1
Bose, C.2
Yam, L.S.3
Soloski, M.J.4
Rupp, F.5
-
79
-
-
0036096843
-
A neuronal receptor, neuropilin-1, is essential for the initiation of the primary immune response
-
Tordjman R, Lepelletier Y, Lemarchandel V, Cambot M, Gaulard P, Hermine O, Romeo PH: A neuronal receptor, neuropilin-1, is essential for the initiation of the primary immune response. Nat Immunol 2002;3:477-482.
-
(2002)
Nat Immunol
, vol.3
, pp. 477-482
-
-
Tordjman, R.1
Lepelletier, Y.2
Lemarchandel, V.3
Cambot, M.4
Gaulard, P.5
Hermine, O.6
Romeo, P.H.7
-
80
-
-
22544434322
-
Suppression of myasthenogenic responses of a T cell line by a dual altered peptide ligand by induction of CD4+CD25+ regulatory cells
-
U S A
-
Aruna BV, Sela M, Mozes E: Suppression of myasthenogenic responses of a T cell line by a dual altered peptide ligand by induction of CD4+CD25+ regulatory cells. Proc Natl Acad Sci U S A 2005;19; 102:10285-10290.
-
(2005)
Proc Natl Acad Sci
, vol.19
, Issue.102
, pp. 10285-10290
-
-
Aruna, B.V.1
Sela, M.2
Mozes, E.3
-
81
-
-
14644400445
-
Retroviral Foxp3 gene transfer ameliorates liver granuloma pathology in Schistosoma mansoni infected mice
-
Singh KP, Gerard HC, Hudson AP, Reddy TR, Boros DL: Retroviral Foxp3 gene transfer ameliorates liver granuloma pathology in Schistosoma mansoni infected mice. Immunology 2005;114:410-417.
-
(2005)
Immunology
, vol.114
, pp. 410-417
-
-
Singh, K.P.1
Gerard, H.C.2
Hudson, A.P.3
Reddy, T.R.4
Boros, D.L.5
-
82
-
-
22344432319
-
Coexpression of CD25 and CD27 identifies FoxP3(+) regulatory T cells in inflamed synovia
-
Ruprecht CR, Gattorno M, Ferlito F, Gregorio A, Martini A, Lanzavecchia A, Sallusto F: Coexpression of CD25 and CD27 identifies FoxP3(+) regulatory T cells in inflamed synovia. J Exp Med 2005; 201:1793-1803.
-
(2005)
J Exp Med
, vol.201
, pp. 1793-1803
-
-
Ruprecht, C.R.1
Gattorno, M.2
Ferlito, F.3
Gregorio, A.4
Martini, A.5
Lanzavecchia, A.6
Sallusto, F.7
-
83
-
-
0033137080
-
Virus and autoimmunity: Induction of autoimmune disease in mice by mouse T lymphotropic virus (MTLV) destroying CD4+ T cells
-
Morse SS, Sakaguchi N, Sakaguchi S: Virus and autoimmunity: induction of autoimmune disease in mice by mouse T lymphotropic virus (MTLV) destroying CD4+ T cells. J Immunol 1999;162:5309-5316.
-
(1999)
J Immunol
, vol.162
, pp. 5309-5316
-
-
Morse, S.S.1
Sakaguchi, N.2
Sakaguchi, S.3
-
84
-
-
23344449020
-
Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
-
Elson CO, Cong Y, McCracken VJ, Dimmitt RA, Lorenz RG, Weaver CT: Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota. Immunol Rev 2005;206:260-276.
-
(2005)
Immunol Rev
, vol.206
, pp. 260-276
-
-
Elson, C.O.1
Cong, Y.2
McCracken, V.J.3
Dimmitt, R.A.4
Lorenz, R.G.5
Weaver, C.T.6
-
85
-
-
0038783387
-
Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: Control by CD4(+) regulatory T cells and IL-10
-
Asseman C, Read S, Powrie F: Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: Control by CD4(+) regulatory T cells and IL-10. J Immunol 2003;171:971-978.
-
(2003)
J Immunol
, vol.171
, pp. 971-978
-
-
Asseman, C.1
Read, S.2
Powrie, F.3
-
86
-
-
0033039741
-
Mucosal Immunity and Inflammation II. The yin and yang of T cells in intestinal inflammation: Pathogenic and protective roles in a mouse colitis model
-
De Winter H, Cheroutre H, Kronenberg M: Mucosal Immunity and Inflammation II. The yin and yang of T cells in intestinal inflammation: pathogenic and protective roles in a mouse colitis model. Am J Physiol Gastrointest Liver Physiol 1999;276: G1317-G1321.
-
(1999)
Am J Physiol Gastrointest Liver Physiol
, vol.276
-
-
De Winter, H.1
Cheroutre, H.2
Kronenberg, M.3
-
87
-
-
16244379546
-
Regulatory T cells and intestinal homeostasis
-
Coombes JL, Robinson NJ, Maloy KJ, Uhlig HH, Powrie F: Regulatory T cells and intestinal homeostasis. Immunol Rev 2005;204:184-194.
-
(2005)
Immunol Rev
, vol.204
, pp. 184-194
-
-
Coombes, J.L.1
Robinson, N.J.2
Maloy, K.J.3
Uhlig, H.H.4
Powrie, F.5
-
88
-
-
19944416542
-
CD4+ T cell mediated intestinal immunity: Chronic inflammation versus immune regulation
-
Westendorf AM, Templin M, Geffers R, Deppenmeier S, Gruber AD, Probst-Kepper M, Hansen W, Liblau RS, Gunzer F, Bruder D, Euer J: CD4+ T cell mediated intestinal immunity: chronic inflammation versus immune regulation. Gut 2005;54: 60-69.
-
(2005)
Gut
, vol.54
, pp. 60-69
-
-
Westendorf, A.M.1
Templin, M.2
Geffers, R.3
Deppenmeier, S.4
Gruber, A.D.5
Probst-Kepper, M.6
Hansen, W.7
Liblau, R.S.8
Gunzer, F.9
Bruder, D.10
Euer, J.11
-
89
-
-
19244371723
-
APECED: A monogenic autoimmune disease providing new clues to self-tolerance
-
Peterson P, Nagamine K, Scott H, Heino M, Kudoh J, Shimizu N, Antonarakis SE, Krohn KJ: APECED: a monogenic autoimmune disease providing new clues to self-tolerance. Immunol Today 1998;19:384-386.
-
(1998)
Immunol Today
, vol.19
, pp. 384-386
-
-
Peterson, P.1
Nagamine, K.2
Scott, H.3
Heino, M.4
Kudoh, J.5
Shimizu, N.6
Antonarakis, S.E.7
Krohn, K.J.8
-
91
-
-
0242407709
-
Transcription factors in autoimmunity
-
Ramsdell F, Ziegler SF: Transcription factors in autoimmunity. Curr Opin Immunol 2003;15:718-724.
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 718-724
-
-
Ramsdell, F.1
Ziegler, S.F.2
-
92
-
-
0037084784
-
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
-
Ramsey C, Winqvist O, Puhakka L, Halonen M, Moro A, Kampe O, Eskelin P, Pelto-Huikko M, Peltonen L: Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum Mol Genet 2002;11:397-409.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 397-409
-
-
Ramsey, C.1
Winqvist, O.2
Puhakka, L.3
Halonen, M.4
Moro, A.5
Kampe, O.6
Eskelin, P.7
Pelto-Huikko, M.8
Peltonen, L.9
-
93
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D: Projection of an immunological self shadow within the thymus by the aire protein. Science 2002;298:1395-1401.
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
Venanzi, E.S.2
Klein, L.3
Chen, Z.4
Berzins, S.P.5
Turley, S.J.6
Von Boehmer, H.7
Bronson, R.8
Dierich, A.9
Benoist, C.10
Mathis, D.11
-
94
-
-
0033590981
-
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla
-
Heino M, Peterson P, Kudoh J, Nagamine K, Lagerstedt A, Ovod V, Ranki A, Rantala I, Nieminen M, Tuukkanen J, Scott HS, Antonarakis SE, Shimizu N, Krohn K: Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. Biochem Biophys Res Commun 1999;257: 821-825.
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 821-825
-
-
Heino, M.1
Peterson, P.2
Kudoh, J.3
Nagamine, K.4
Lagerstedt, A.5
Ovod, V.6
Ranki, A.7
Rantala, I.8
Nieminen, M.9
Tuukkanen, J.10
Scott, H.S.11
Antonarakis, S.E.12
Shimizu, N.13
Krohn, K.14
-
95
-
-
0036644686
-
Promiscuous gene expression and central T-cell tolerance: More than meets the eye
-
Kyewski B, Derbinski J, Gotter J, Klein L: Promiscuous gene expression and central T-cell tolerance: more than meets the eye. Trends Immunol 2002;23: 364-371.
-
(2002)
Trends Immunol
, vol.23
, pp. 364-371
-
-
Kyewski, B.1
Derbinski, J.2
Gotter, J.3
Klein, L.4
-
96
-
-
22344449972
-
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
-
Derbinski J, Gabler J, Brors B, Tierling S, Jonnakuty S, Hergenhahn M, Peltonen L, Walter J, Kyewski B: Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J Exp Med 2005;202:33-45.
-
(2005)
J Exp Med
, vol.202
, pp. 33-45
-
-
Derbinski, J.1
Gabler, J.2
Brors, B.3
Tierling, S.4
Jonnakuty, S.5
Hergenhahn, M.6
Peltonen, L.7
Walter, J.8
Kyewski, B.9
-
97
-
-
23844558032
-
The cellular mechanism of Aire control of T cell tolerance
-
Anderson MS, Venanzi ES, Chen Z, Berzins SP, Benoist C, Mathis D: The cellular mechanism of Aire control of T cell tolerance. Immunity 2005;23: 227-239.
-
(2005)
Immunity
, vol.23
, pp. 227-239
-
-
Anderson, M.S.1
Venanzi, E.S.2
Chen, Z.3
Berzins, S.P.4
Benoist, C.5
Mathis, D.6
-
98
-
-
0035806323
-
Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
-
Levings MK, Sangregorio R, Roncarolo MG: Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J Exp Med 2001;193:1295-1302.
-
(2001)
J Exp Med
, vol.193
, pp. 1295-1302
-
-
Levings, M.K.1
Sangregorio, R.2
Roncarolo, M.G.3
-
99
-
-
0035806290
-
Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
-
Jonuleit H, Schmitt E, Stassen M, Tuettenberg A, Knop J, Enk AH: Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J Exp Med 2001;193:1285-1294.
-
(2001)
J Exp Med
, vol.193
, pp. 1285-1294
-
-
Jonuleit, H.1
Schmitt, E.2
Stassen, M.3
Tuettenberg, A.4
Knop, J.5
Enk, A.H.6
-
100
-
-
0035806276
-
CD4(+) CD25 (+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
-
Taylor PA, Noelle RJ, Blazar BR: CD4(+) CD25 (+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade. J Exp Med 2001;193:1311-1318.
-
(2001)
J Exp Med
, vol.193
, pp. 1311-1318
-
-
Taylor, P.A.1
Noelle, R.J.2
Blazar, B.R.3
-
101
-
-
0035869432
-
IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
-
Hara M, Kingsley CI, Niimi M, Read S, Turvey SE, Bushell AR, Morris PJ, Powrie F, Wood KJ: IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J Immunol 2001; 166:3789-3796.
-
(2001)
J Immunol
, vol.166
, pp. 3789-3796
-
-
Hara, M.1
Kingsley, C.I.2
Niimi, M.3
Read, S.4
Turvey, S.E.5
Bushell, A.R.6
Morris, P.J.7
Powrie, F.8
Wood, K.J.9
-
102
-
-
0035881234
-
Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance
-
Gregori S, Casorati M, Amuchastegui S, Smiroldo S, Davalli AM, Adorini L: Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 2001;167:1945-1953.
-
(2001)
J Immunol
, vol.167
, pp. 1945-1953
-
-
Gregori, S.1
Casorati, M.2
Amuchastegui, S.3
Smiroldo, S.4
Davalli, A.M.5
Adorini, L.6
-
103
-
-
21144436219
-
Regulatory T cells, derived from naive CD4+CD25- T cells by in vitro Foxp3 gene transfer, can induce transplantation tolerance
-
Chai JG, Xue SA, Coe D, Addey C, Bartok I, Scott D, Simpson E, Stauss HJ, Hori S, Sakaguchi S, Dyson J: Regulatory T cells, derived from naive CD4+CD25- T cells by in vitro Foxp3 gene transfer, can induce transplantation tolerance. Transplantation 2005;79:1310-1316.
-
(2005)
Transplantation
, vol.79
, pp. 1310-1316
-
-
Chai, J.G.1
Xue, S.A.2
Coe, D.3
Addey, C.4
Bartok, I.5
Scott, D.6
Simpson, E.7
Stauss, H.J.8
Hori, S.9
Sakaguchi, S.10
Dyson, J.11
-
104
-
-
0032400989
-
Linked suppression of skin graft rejection can operate through indirect recognition
-
Wise MP, Bemelman F, Cobbold SP, Waldmann H: Linked suppression of skin graft rejection can operate through indirect recognition. J Immunol 1998;161:5813-5816.
-
(1998)
J Immunol
, vol.161
, pp. 5813-5816
-
-
Wise, M.P.1
Bemelman, F.2
Cobbold, S.P.3
Waldmann, H.4
-
105
-
-
0033213948
-
Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta
-
Zeller JC, Panoskaltsis-Mortari A, Murphy WJ, Ruscetti FW, Narula S, Roncarolo MG, Blazar BR: Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta. J Immunol 1999;163:3684-3691.
-
(1999)
J Immunol
, vol.163
, pp. 3684-3691
-
-
Zeller, J.C.1
Panoskaltsis-Mortari, A.2
Murphy, W.J.3
Ruscetti, F.W.4
Narula, S.5
Roncarolo, M.G.6
Blazar, B.R.7
-
106
-
-
0032146529
-
CD4(+) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses
-
Blazar BR, Taylor PA, Noelle RJ, Vallera DA: CD4(+) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses. J Clin Invest 1998;102:473-482.
-
(1998)
J Clin Invest
, vol.102
, pp. 473-482
-
-
Blazar, B.R.1
Taylor, P.A.2
Noelle, R.J.3
Vallera, D.A.4
-
107
-
-
0029162602
-
Transplantation tolerance induced by antigen pretreatment and depleting anti-CD4 antibody depends on CD4+ T cell regulation during the induction phase of the response
-
Bushell A, Morris PJ, Wood KJ: Transplantation tolerance induced by antigen pretreatment and depleting anti-CD4 antibody depends on CD4+ T cell regulation during the induction phase of the response. Eur J Immunol 1995;25:2643-2649.
-
(1995)
Eur J Immunol
, vol.25
, pp. 2643-2649
-
-
Bushell, A.1
Morris, P.J.2
Wood, K.J.3
-
108
-
-
0034722630
-
Nondepleting anti-CD4 monoclonal antibody enhances the ability of oral alloantigen delivery to induce indefinite survival of cardiac allografts: Oral tolerance to alloantigen
-
Niimi M, Witzke O, Bushell A, Hara M, Morris PJ, Wood KJ: Nondepleting anti-CD4 monoclonal antibody enhances the ability of oral alloantigen delivery to induce indefinite survival of cardiac allografts: oral tolerance to alloantigen. Transplantation 2000;70:1524-1528.
-
(2000)
Transplantation
, vol.70
, pp. 1524-1528
-
-
Niimi, M.1
Witzke, O.2
Bushell, A.3
Hara, M.4
Morris, P.J.5
Wood, K.J.6
-
109
-
-
0030970045
-
Induction of donor specific transplantation tolerance to cardiac allografts following treatment with nondepleting (RIB 5/2) or depleting (OX-38) anti-CD4 mAb plus intrathymic or intravenous donor alloantigen
-
Arima T, Lehmann M, Flye MW: Induction of donor specific transplantation tolerance to cardiac allografts following treatment with nondepleting (RIB 5/2) or depleting (OX-38) anti-CD4 mAb plus intrathymic or intravenous donor alloantigen. Transplantation 1997;63:284-292.
-
(1997)
Transplantation
, vol.63
, pp. 284-292
-
-
Arima, T.1
Lehmann, M.2
Flye, M.W.3
-
110
-
-
0031970667
-
Long-term survival of hamster islet xenografts in mice under short-course treatment with nondepleting versus depleting anti-CD4 monoclonal antibodies
-
Lu X, Schulz M, Zihlmann HR, Borel JF: Long-term survival of hamster islet xenografts in mice under short-course treatment with nondepleting versus depleting anti-CD4 monoclonal antibodies. Xenotransplantation 1998;5:154-163.
-
(1998)
Xenotransplantation
, vol.5
, pp. 154-163
-
-
Lu, X.1
Schulz, M.2
Zihlmann, H.R.3
Borel, J.F.4
-
111
-
-
0030779892
-
Tolerance to heart and kidney grafts induced by nondepleting anti-CD4 monoclonal antibody (RIB 5/2) versus depleting anti-CD4 monoclonal antibody (OX-38) with donor antigen administration
-
Motoyama K, Arima T, Lehmann M, Flye MW: Tolerance to heart and kidney grafts induced by nondepleting anti-CD4 monoclonal antibody (RIB 5/2) versus depleting anti-CD4 monoclonal antibody (OX-38) with donor antigen administration. Surgery 1997;122:213-219.
-
(1997)
Surgery
, vol.122
, pp. 213-219
-
-
Motoyama, K.1
Arima, T.2
Lehmann, M.3
Flye, M.W.4
-
113
-
-
0037364976
-
Regulatory T cells in transplantation tolerance
-
Wood KJ, Sakaguchi S: Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003; 3:199-210.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 199-210
-
-
Wood, K.J.1
Sakaguchi, S.2
-
114
-
-
0036467522
-
CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
-
Kingsley CI, Karim M, Bushell AR, Wood KJ: CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J Immunol 2002;168: 1080-1086.
-
(2002)
J Immunol
, vol.168
, pp. 1080-1086
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
115
-
-
1642454708
-
Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process
-
Karim M, Kingsley CI, Bushell AR, Sawitzki BS, Wood KJ: Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process. J Immunol 2004;172:923-928.
-
(2004)
J Immunol
, vol.172
, pp. 923-928
-
-
Karim, M.1
Kingsley, C.I.2
Bushell, A.R.3
Sawitzki, B.S.4
Wood, K.J.5
-
116
-
-
0027479685
-
'Infectious' transplantation tolerance
-
Qin S, Cobbold SP, Pope H, Elliott J, Kioussis D, Davies J, Waldmann H: 'Infectious' transplantation tolerance. Science 1993;259:974-977.
-
(1993)
Science
, vol.259
, pp. 974-977
-
-
Qin, S.1
Cobbold, S.P.2
Pope, H.3
Elliott, J.4
Kioussis, D.5
Davies, J.6
Waldmann, H.7
-
117
-
-
0037099719
-
Infectious tolerance: Human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells
-
Jonuleit H, Schmitt E, Kakirman H, Stassen M, Knop J, Enk AH: Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells. J Exp Med 2002;196:255-260.
-
(2002)
J Exp Med
, vol.196
, pp. 255-260
-
-
Jonuleit, H.1
Schmitt, E.2
Kakirman, H.3
Stassen, M.4
Knop, J.5
Enk, A.H.6
-
118
-
-
0030461536
-
Amplification of natural regulatory immune mechanisms for transplantation tolerance
-
Chen ZK, Cobbold SP, Waldmann H, Metcalfe S: Amplification of natural regulatory immune mechanisms for transplantation tolerance. Transplantation 1996;62:1200-1206.
-
(1996)
Transplantation
, vol.62
, pp. 1200-1206
-
-
Chen, Z.K.1
Cobbold, S.P.2
Waldmann, H.3
Metcalfe, S.4
-
120
-
-
4043102582
-
Regulatory cells and infectious agents: Detentes cordiale and contraire
-
Rouse BT, Suvas S: Regulatory cells and infectious agents: detentes cordiale and contraire. J Immunol 2004;173:2211-2215.
-
(2004)
J Immunol
, vol.173
, pp. 2211-2215
-
-
Rouse, B.T.1
Suvas, S.2
-
121
-
-
8544242704
-
Regulatory T cells: Friend or foe in immunity to infection?
-
Mills KH: Regulatory T cells: friend or foe in immunity to infection? Nat Rev Immunol 2004;4: 841-855.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 841-855
-
-
Mills, K.H.1
-
122
-
-
16844369607
-
Natural regulatory T cells in infectious disease
-
Belkaid Y, Rouse BT: Natural regulatory T cells in infectious disease. Nat Immunol 2005;6:353-360.
-
(2005)
Nat Immunol
, vol.6
, pp. 353-360
-
-
Belkaid, Y.1
Rouse, B.T.2
-
123
-
-
0036107373
-
CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice
-
Hori S, Carvalho TL, Demengeot J: CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice. Eur J Immunol 2002;32:1282-1291.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1282-1291
-
-
Hori, S.1
Carvalho, T.L.2
Demengeot, J.3
-
124
-
-
0037795727
-
Absence of CD4+CD 25+ regulatory T cells is associated with a loss of regulation leading to increased pathology in Helicobacter pylori-infected mice
-
Raghavan S, Eredriksson M, Svennerholm AM, Holmgren J, Suri-Payer E: Absence of CD4+CD 25+ regulatory T cells is associated with a loss of regulation leading to increased pathology in Helicobacter pylori-infected mice. Clin Exp Immunol 2003;132:393-400.
-
(2003)
Clin Exp Immunol
, vol.132
, pp. 393-400
-
-
Raghavan, S.1
Eredriksson, M.2
Svennerholm, A.M.3
Holmgren, J.4
Suri-Payer, E.5
-
125
-
-
0344405680
-
Helicobacter pylori-specific CD4+ CD25high regulatory T cells suppress memory T-cell responses to H. pylori in infected individuals
-
Lundgren A, Suri-Payer E, Enarsson K, Svennerholm AM, Lundin BS: Helicobacter pylori-specific CD4+ CD25high regulatory T cells suppress memory T-cell responses to H. pylori in infected individuals. Infect Immun 2003;71:1755-1762.
-
(2003)
Infect Immun
, vol.71
, pp. 1755-1762
-
-
Lundgren, A.1
Suri-Payer, E.2
Enarsson, K.3
Svennerholm, A.M.4
Lundin, B.S.5
-
126
-
-
19944404220
-
Mucosal FOXP3-expressing CD4+ CD25high regulatory T cells in Helicobacter pylori-infected patients
-
Lundgren A, Stromberg E, Sjoling A, Lindhohn C, Enarsson K, Edebo A, Johnsson E, Suri-Payer E, Larsson P, Rudin A, Svennerholm AM, Lundin BS: Mucosal FOXP3-expressing CD4+ CD25high regulatory T cells in Helicobacter pylori-infected patients. Infect Immun 2005;73:523-531.
-
(2005)
Infect Immun
, vol.73
, pp. 523-531
-
-
Lundgren, A.1
Stromberg, E.2
Sjoling, A.3
Lindhohn, C.4
Enarsson, K.5
Edebo, A.6
Johnsson, E.7
Suri-Payer, E.8
Larsson, P.9
Rudin, A.10
Svennerholm, A.M.11
Lundin, B.S.12
-
127
-
-
3543098686
-
CD25(+) CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status
-
Kinter AL, Hennessey M, Bell A, Kern S, Lin Y, Daucher M, Planta M, McGlaughlin M, Jackson R, Ziegler SE, Fauci AS: CD25(+) CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J Exp Med 2004;200: 331-343.
-
(2004)
J Exp Med
, vol.200
, pp. 331-343
-
-
Kinter, A.L.1
Hennessey, M.2
Bell, A.3
Kern, S.4
Lin, Y.5
Daucher, M.6
Planta, M.7
McGlaughlin, M.8
Jackson, R.9
Ziegler, S.E.10
Fauci, A.S.11
-
128
-
-
22344457984
-
FOXP3 mRNA levels are decreased in peripheral blood CD4+ lymphocytes from HIV-positive patients
-
Apoil PA, Puissant B, Roubinet F, Abbal M, Massip P, Blancher A: FOXP3 mRNA levels are decreased in peripheral blood CD4+ lymphocytes from HIV-positive patients. J Acquir Immune Defic Syndr 2005;39:381-385.
-
(2005)
J Acquir Immune Defic Syndr
, vol.39
, pp. 381-385
-
-
Apoil, P.A.1
Puissant, B.2
Roubinet, F.3
Abbal, M.4
Massip, P.5
Blancher, A.6
-
129
-
-
9644303011
-
CD4 T Lymphocyte-mediated lung disease: Steady state between pathological and tolerogenic immune reactions
-
Bruder D, Westendorf AM, Geffers R, Gruber AD, Gereke M, Enelow RI, Buer J: CD4 T Lymphocyte-mediated lung disease: steady state between pathological and tolerogenic immune reactions. Am J Respir Crit Care Med 2004;170:1145-1152.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 1145-1152
-
-
Bruder, D.1
Westendorf, A.M.2
Geffers, R.3
Gruber, A.D.4
Gereke, M.5
Enelow, R.I.6
Buer, J.7
-
130
-
-
7044247947
-
An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection
-
Cabrera R, Tu Z, Xu Y, Firpi RJ, Rosen HR, Liu C, Nelson DR: An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection. Hepatology 2004;40:1062-1071.
-
(2004)
Hepatology
, vol.40
, pp. 1062-1071
-
-
Cabrera, R.1
Tu, Z.2
Xu, Y.3
Firpi, R.J.4
Rosen, H.R.5
Liu, C.6
Nelson, D.R.7
-
131
-
-
0025179982
-
Elimination of cycling CD4+ suppressor T cells with an anti-mitotic drug releases non-cycling CD8+ T cells to cause regression of an advanced lymphoma
-
North RJ, Awwad M: Elimination of cycling CD4+ suppressor T cells with an anti-mitotic drug releases non-cycling CD8+ T cells to cause regression of an advanced lymphoma. Immunology 1990;71:90-95.
-
(1990)
Immunology
, vol.71
, pp. 90-95
-
-
North, R.J.1
Awwad, M.2
-
132
-
-
0033571105
-
Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity
-
Shimizu J, Yamazaki S, Sakaguchi S: Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol 1999;163:5211-5218.
-
(1999)
J Immunol
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
Yamazaki, S.2
Sakaguchi, S.3
-
133
-
-
0036858838
-
Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens
-
Golgher D, Jones E, Powrie F, Elliott T, Gallimore A: Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens. Eur J Immunol 2002;32:3267-3275.
-
(2002)
Eur J Immunol
, vol.32
, pp. 3267-3275
-
-
Golgher, D.1
Jones, E.2
Powrie, F.3
Elliott, T.4
Gallimore, A.5
-
134
-
-
3242736641
-
Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice
-
Jones E, Dahm-Vicker M, Simon AK, Green A, Powrie F, Cerundolo V, Gallimore A: Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice. Cancer Immun 2002;2:1.
-
(2002)
Cancer Immun
, vol.2
, pp. 1
-
-
Jones, E.1
Dahm-Vicker, M.2
Simon, A.K.3
Green, A.4
Powrie, F.5
Cerundolo, V.6
Gallimore, A.7
-
135
-
-
0035903324
-
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
-
Sutmuller RP, van Duivenvoorde LM, van Elsas A, Schumacher TN, Wildenberg ME, Allison JP, Toes RE, Offringa R, Melief CJ: Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 2001;194:823-832.
-
(2001)
J Exp Med
, vol.194
, pp. 823-832
-
-
Sutmuller, R.P.1
Van Duivenvoorde, L.M.2
Van Elsas, A.3
Schumacher, T.N.4
Wildenberg, M.E.5
Allison, J.P.6
Toes, R.E.7
Offringa, R.8
Melief, C.J.9
-
136
-
-
1642378018
-
CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative
-
Ghiringhelli F, Larmonier N, Schmitt E, Parcellier A, Cathelin D, Garrido C, Chauffert B, Solary E, Bonnotte B, Martin F: CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative. Eur J Immunol 2004;34:336-344.
-
(2004)
Eur J Immunol
, vol.34
, pp. 336-344
-
-
Ghiringhelli, F.1
Larmonier, N.2
Schmitt, E.3
Parcellier, A.4
Cathelin, D.5
Garrido, C.6
Chauffert, B.7
Solary, E.8
Bonnotte, B.9
Martin, F.10
-
137
-
-
10744222813
-
Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens
-
Phan GQ, Touloukian CE, Yang JC, Restifo NP, Sherry RM, Hwu P, Topalian SL, Schwartzentruber DJ, Seipp CA, Freezer LJ, Morton KE, Mavroukakis SA, White DE, Rosenberg SA: Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens. J Immunother 2003;26:349-356.
-
(2003)
J Immunother
, vol.26
, pp. 349-356
-
-
Phan, G.Q.1
Touloukian, C.E.2
Yang, J.C.3
Restifo, N.P.4
Sherry, R.M.5
Hwu, P.6
Topalian, S.L.7
Schwartzentruber, D.J.8
Seipp, C.A.9
Freezer, L.J.10
Morton, K.E.11
Mavroukakis, S.A.12
White, D.E.13
Rosenberg, S.A.14
-
138
-
-
3142737258
-
Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
-
Viguier M, Lemaitre F, Verola O, Cho MS, Gorochov G, Dubertret L, Bachelez H, Kourilsky P, Ferradini L: Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J Immunol 2004; 173:1444-1453.
-
(2004)
J Immunol
, vol.173
, pp. 1444-1453
-
-
Viguier, M.1
Lemaitre, F.2
Verola, O.3
Cho, M.S.4
Gorochov, G.5
Dubertret, L.6
Bachelez, H.7
Kourilsky, P.8
Ferradini, L.9
-
139
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, Evdemon-Hogan M, Conejo-Garcia JR, Zhang L, Burow M, Zhu Y, Wei S, Kryczek I, Daniel B, Gordon A, Myers L, Lackner A, Disis ML, Knutson KL, Chen L, Zou W: Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 2004;10:942-949.
-
(2004)
Nat Med
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
Evdemon-Hogan, M.7
Conejo-Garcia, J.R.8
Zhang, L.9
Burow, M.10
Zhu, Y.11
Wei, S.12
Kryczek, I.13
Daniel, B.14
Gordon, A.15
Myers, L.16
Lackner, A.17
Disis, M.L.18
Knutson, K.L.19
Chen, L.20
Zou, W.21
more..
-
140
-
-
1642497640
-
Tumor-specific human CD4+ regulatory T cells and their ligands: Implications for immunotherapy
-
Wang HY, Lee DA, Peng G, Guo Z, Li Y, Kiniwa Y, Shevach EM, Wang RF: Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy. Immunity 2004;20:107-118.
-
(2004)
Immunity
, vol.20
, pp. 107-118
-
-
Wang, H.Y.1
Lee, D.A.2
Peng, G.3
Guo, Z.4
Li, Y.5
Kiniwa, Y.6
Shevach, E.M.7
Wang, R.F.8
-
141
-
-
14044257258
-
Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells
-
Wang HY, Peng G, Guo Z, Shevach EM, Wang RF: Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells. J Immunol 2005; 174:2661-2670.
-
(2005)
J Immunol
, vol.174
, pp. 2661-2670
-
-
Wang, H.Y.1
Peng, G.2
Guo, Z.3
Shevach, E.M.4
Wang, R.F.5
-
142
-
-
0141796312
-
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
-
Belghith M, Bluestone JA, Harriot S, Megret J, Bach JF, Chatenoud L: TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 2003;9:1202-1208.
-
(2003)
Nat Med
, vol.9
, pp. 1202-1208
-
-
Belghith, M.1
Bluestone, J.A.2
Harriot, S.3
Megret, J.4
Bach, J.F.5
Chatenoud, L.6
-
143
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
Tang Q, Henriksen KJ, Bi M, Finger EB, Szot G, Ye J, Masteller EL, McDevitt H, Bonyhadi M, Bluestone JA: In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med 2004;199:1455-1465.
-
(2004)
J Exp Med
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
Masteller, E.L.7
McDevitt, H.8
Bonyhadi, M.9
Bluestone, J.A.10
-
144
-
-
2942692039
-
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
-
Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM: CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med 2004; 199:1467-1477.
-
(2004)
J Exp Med
, vol.199
, pp. 1467-1477
-
-
Tarbell, K.V.1
Yamazaki, S.2
Olson, K.3
Toy, P.4
Steinman, R.M.5
-
145
-
-
2542420993
-
In vivo instruction oi suppressor commitment in naive T cells
-
Apostolou I, von Boehmer H: In vivo instruction oi suppressor commitment in naive T cells. J Exp Med 2004;199:1401-1408.
-
(2004)
J Exp Med
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
Von Boehmer, H.2
-
146
-
-
33644691658
-
On the edge ot autoimmunity: T cell stimulation by steady state dendritic cells prevents autoimmune diabetes
-
in press
-
Bruder D, Westendorf AM, Hansen W, Prettin S, Gruber AD, Qian Y, von Boehmer H, Mahnke K, Buer J: On the edge ot autoimmunity: T cell stimulation by steady state dendritic cells prevents autoimmune diabetes. Diabetes, in press.
-
Diabetes
-
-
Bruder, D.1
Westendorf, A.M.2
Hansen, W.3
Prettin, S.4
Gruber, A.D.5
Qian, Y.6
Von Boehmer, H.7
Mahnke, K.8
Buer, J.9
-
147
-
-
0032472406
-
Changes in function of antigen-specific lymphocytes correlating with progression towards diabetes in a transgenic model
-
Sarukhan A, Lanoue A, Franzke A, Brousse N, Buer J, von Boehmer H: Changes in function of antigen-specific lymphocytes correlating with progression towards diabetes in a transgenic model. EMBO J 1998;17:71-80.
-
(1998)
EMBO J
, vol.17
, pp. 71-80
-
-
Sarukhan, A.1
Lanoue, A.2
Franzke, A.3
Brousse, N.4
Buer, J.5
Von Boehmer, H.6
-
148
-
-
27144509163
-
A network-based analysis of systemic inflammation in humans
-
Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, Miller-Graziano C, Moldawer LL, Mindrinos MN, Davis RW, Tompkins RG, Lowry SF, Large Scale Collab Res Program: A network-based analysis of systemic inflammation in humans. Nature 2005;437(7061): 1032-1037.
-
(2005)
Nature
, vol.437
, Issue.7061
, pp. 1032-1037
-
-
Calvano, S.E.1
Xiao, W.2
Richards, D.R.3
Felciano, R.M.4
Baker, H.V.5
Cho, R.J.6
Chen, R.O.7
Brownstein, B.H.8
Cobb, J.P.9
Tschoeke, S.K.10
Miller-Graziano, C.11
Moldawer, L.L.12
Mindrinos, M.N.13
Davis, R.W.14
Tompkins, R.G.15
Lowry, S.F.16
-
149
-
-
4644285392
-
E3 ubiquitin ligases as T cell anergy factors
-
Mueller DL: E3 ubiquitin ligases as T cell anergy factors. Nat Immunol 2004;5:883-890.
-
(2004)
Nat Immunol
, vol.5
, pp. 883-890
-
-
Mueller, D.L.1
-
150
-
-
5644263642
-
Role of LAG-3 in regulatory T cells
-
Huang CT, Workman CJ, Flies D, Pan X, Marson AL, Zhou G, et al: Role of LAG-3 in regulatory T cells. Immunity 2004;21:503-513.
-
(2004)
Immunity
, vol.21
, pp. 503-513
-
-
Huang, C.T.1
Workman, C.J.2
Flies, D.3
Pan, X.4
Marson, A.L.5
Zhou, G.6
-
151
-
-
1242345130
-
Antigen-specific regulatory T cells - Their induction and role in infection
-
Mills KHG, McGuirk P: Antigen-specific regulatory T cells - their induction and role in infection. Semin Immunol 2004;16:107-117.
-
(2004)
Semin Immunol
, vol.16
, pp. 107-117
-
-
Mills, K.H.G.1
McGuirk, P.2
|