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Volumn 25, Issue 12, 2005, Pages 1557-1572

Epilepsy and apoptosis pathways

Author keywords

14 3 3; Apoptosis; Death receptor; Endoplasmic reticulum; Mitochondria; Necrosis; Neurodegeneration

Indexed keywords

BIM PROTEIN; CASPASE; CASPASE 3; FAS LIGAND; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN P15; PROTEIN P22; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 28044450402     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600149     Document Type: Review
Times cited : (211)

References (144)
  • 1
    • 0037827756 scopus 로고    scopus 로고
    • The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death
    • Akbar MT, Lundberg AM, Liu K, Vidyadaran S, Wells KE, Dolatshad H et al (2003) The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death. J Biol Chem 278:19956-65
    • (2003) J Biol Chem , vol.278 , pp. 19956-19965
    • Akbar, M.T.1    Lundberg, A.M.2    Liu, K.3    Vidyadaran, S.4    Wells, K.E.5    Dolatshad, H.6
  • 2
    • 0035975622 scopus 로고    scopus 로고
    • Heat shock protein 27 shows a distinctive widespread spatial and temporal pattern of induction in CNS glial and neuronal cells compared to heat shock protein 70 and caspase 3 following kainate administration
    • Akbar MT, Wells DJ, Latchman DS, de Belleroche J (2001) Heat shock protein 27 shows a distinctive widespread spatial and temporal pattern of induction in CNS glial and neuronal cells compared to heat shock protein 70 and caspase 3 following kainate administration. Brain Res Mol Brain Res 93:148-63
    • (2001) Brain Res Mol Brain Res , vol.93 , pp. 148-163
    • Akbar, M.T.1    Wells, D.J.2    Latchman, D.S.3    De Belleroche, J.4
  • 3
    • 0035888246 scopus 로고    scopus 로고
    • Potential roles for tumor necrosis factor and nuclear factor-kappaB in seizure activity
    • Albensi BC (2001) Potential roles for tumor necrosis factor and nuclear factor-kappaB in seizure activity. J Neurosci Res 66:151-4
    • (2001) J Neurosci Res , vol.66 , pp. 151-154
    • Albensi, B.C.1
  • 5
    • 0035888112 scopus 로고    scopus 로고
    • Domoic acid-induced neuronal damage in the rat hippocampus: Changes in apoptosis related genes (bcl-2, bax, caspase-3) and microglial response
    • Ananth C, Thameem Dheen S, Gopalakrishnakone P, Kaur C (2001) Domoic acid-induced neuronal damage in the rat hippocampus: changes in apoptosis related genes (bcl-2, bax, caspase-3) and microglial response. J Neurosci Res 66:177-90
    • (2001) J Neurosci Res , vol.66 , pp. 177-190
    • Ananth, C.1    Thameem Dheen, S.2    Gopalakrishnakone, P.3    Kaur, C.4
  • 6
    • 0036708173 scopus 로고    scopus 로고
    • Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse
    • Araki T, Simon RP, Taki W, Lan J-Q, Henshall DC (2002) Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse. J Neurosci Res 69:614-21
    • (2002) J Neurosci Res , vol.69 , pp. 614-621
    • Araki, T.1    Simon, R.P.2    Taki, W.3    Lan, J.-Q.4    Henshall, D.C.5
  • 7
    • 0032910169 scopus 로고    scopus 로고
    • Apoptosis control by death and decoy receptors
    • Ashkenazi A, Dixit VM (1999) Apoptosis control by death and decoy receptors. Curr Opin Cell Biol 11:255-60
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 255-260
    • Ashkenazi, A.1    Dixit, V.M.2
  • 10
    • 0037466759 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor blockade after status epilepticus protects against limbic brain damage but not against epilepsy in kainate model of temporal lobe epilepsy
    • Brandt C, Potschka H, Loscher W, Ebert U (2003) N-methyl-D-aspartate receptor blockade after status epilepticus protects against limbic brain damage but not against epilepsy in kainate model of temporal lobe epilepsy. Neuroscience 118:727-40
    • (2003) Neuroscience , vol.118 , pp. 727-740
    • Brandt, C.1    Potschka, H.2    Loscher, W.3    Ebert, U.4
  • 11
    • 0036227608 scopus 로고    scopus 로고
    • Seizure-associated hippocampal volume loss: A longitudinal magnetic resonance study of temporal lobe epilepsy
    • Briellmann RS, Berkovic SF, Syngeniotis A, King MA, Jackson GD (2002) Seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy. Ann Neurol 51:641-4
    • (2002) Ann Neurol , vol.51 , pp. 641-644
    • Briellmann, R.S.1    Berkovic, S.F.2    Syngeniotis, A.3    King, M.A.4    Jackson, G.D.5
  • 12
    • 3242687976 scopus 로고    scopus 로고
    • Spontaneous recurrent seizure following status epilepticus enhances dentate gyrus neurogenesis
    • Cha BH, Akman C, Silveira DC, Liu X, Holmes GL (2004) Spontaneous recurrent seizure following status epilepticus enhances dentate gyrus neurogenesis. Brain Dev 26:394-7
    • (2004) Brain Dev , vol.26 , pp. 394-397
    • Cha, B.H.1    Akman, C.2    Silveira, D.C.3    Liu, X.4    Holmes, G.L.5
  • 14
    • 19944432123 scopus 로고    scopus 로고
    • Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
    • Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG et al (2005) Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell 17:393-403
    • (2005) Mol Cell , vol.17 , pp. 393-403
    • Chen, L.1    Willis, S.N.2    Wei, A.3    Smith, B.J.4    Fletcher, J.I.5    Hinds, M.G.6
  • 15
    • 13844298651 scopus 로고    scopus 로고
    • Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms
    • Cheung EC, Melanson-Drapeau L, Cregan SP, Vanderluit JL, Ferguson KL, McIntosh WC et al (2005) Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms. J Neurosci 25:1324-34
    • (2005) J Neurosci , vol.25 , pp. 1324-1334
    • Cheung, E.C.1    Melanson-Drapeau, L.2    Cregan, S.P.3    Vanderluit, J.L.4    Ferguson, K.L.5    McIntosh, W.C.6
  • 16
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • Cory S, Adams JM (2002) The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2:647-56
    • (2002) Nat Rev Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 17
    • 0041357164 scopus 로고    scopus 로고
    • BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis
    • Danial NN, Gramm CF, Scorrano L, Zhang CY, Krauss S, Ranger AM et al (2003) BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature 424:952-6
    • (2003) Nature , vol.424 , pp. 952-956
    • Danial, N.N.1    Gramm, C.F.2    Scorrano, L.3    Zhang, C.Y.4    Krauss, S.5    Ranger, A.M.6
  • 18
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial NN, Korsmeyer SJ (2004) Cell death: critical control points. Cell 116:205-19
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 19
    • 0034699033 scopus 로고    scopus 로고
    • Caspase activity plays an essential role in long-term memory
    • Dash PK, Blum S, Moore AN (2000) Caspase activity plays an essential role in long-term memory. Neuroreport 11:2811-6
    • (2000) Neuroreport , vol.11 , pp. 2811-2816
    • Dash, P.K.1    Blum, S.2    Moore, A.N.3
  • 20
    • 0037418861 scopus 로고    scopus 로고
    • Cell biology. Apoptosis - The calcium connection
    • Demaurex N, Distelhorst C (2003) Cell biology. Apoptosis - the calcium connection. Science 300:65-7
    • (2003) Science , vol.300 , pp. 65-67
    • Demaurex, N.1    Distelhorst, C.2
  • 22
    • 0033835065 scopus 로고    scopus 로고
    • Fas engagement accelerates liver regeneration after partial hepatectomy
    • Desbarats J, Newell MK (2000) Fas engagement accelerates liver regeneration after partial hepatectomy. Nat Med 6:920-3
    • (2000) Nat Med , vol.6 , pp. 920-923
    • Desbarats, J.1    Newell, M.K.2
  • 23
    • 0037085319 scopus 로고    scopus 로고
    • Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain
    • Dorr J, Bechmann I, Waiczies S, Aktas O, Walczak H, Krammer PH et al (2002) Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain. J Neurosci 22:RC209
    • (2002) J Neurosci , vol.22
    • Dorr, J.1    Bechmann, I.2    Waiczies, S.3    Aktas, O.4    Walczak, H.5    Krammer, P.H.6
  • 24
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du C, Fang M, Li Y, Li L, Wang X (2000) Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102:33-42
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 25
    • 0036333854 scopus 로고    scopus 로고
    • Delayed sclerosis, neuroprotection, and limbic epileptogenesis after status epilepticus in the rat
    • Ebert U, Brandt C, Loscher W (2002) Delayed sclerosis, neuroprotection, and limbic epileptogenesis after status epilepticus in the rat. Epilepsia 43:86-95
    • (2002) Epilepsia , vol.43 , pp. 86-95
    • Ebert, U.1    Brandt, C.2    Loscher, W.3
  • 26
    • 0035783732 scopus 로고    scopus 로고
    • Caspase inhibitors increase short-term survival of progenitor-cell progeny in the adult rat dentate gyrus following status epilepticus
    • Ekdahl CT, Mohapel P, Elmer E, Lindvall O (2001) Caspase inhibitors increase short-term survival of progenitor-cell progeny in the adult rat dentate gyrus following status epilepticus. Eur J Neurosci 14:937-45
    • (2001) Eur J Neurosci , vol.14 , pp. 937-945
    • Ekdahl, C.T.1    Mohapel, P.2    Elmer, E.3    Lindvall, O.4
  • 27
    • 0022497852 scopus 로고
    • Genetic control of programmed cell death in the nematode C. elegans
    • Ellis HM, Horvitz HR (1986) Genetic control of programmed cell death in the nematode C. elegans. Cell 44:817-29
    • (1986) Cell , vol.44 , pp. 817-829
    • Ellis, H.M.1    Horvitz, H.R.2
  • 28
    • 0033040857 scopus 로고    scopus 로고
    • Caspase-3-dependent neuronal death in the hippocampus following kainic acid treatment
    • Faherty CJ, Xanthoudakis S, Smeyne RJ (1999) Caspase-3-dependent neuronal death in the hippocampus following kainic acid treatment. Brain Res Mol Brain Res 70:159-63
    • (1999) Brain Res Mol Brain Res , vol.70 , pp. 159-163
    • Faherty, C.J.1    Xanthoudakis, S.2    Smeyne, R.J.3
  • 29
    • 0347091260 scopus 로고    scopus 로고
    • BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development
    • Fannjiang Y, Kim CH, Huganir RL, Zou S, Lindsten T, Thompson CB et al (2003) BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development. Dev Cell 4:575-85
    • (2003) Dev Cell , vol.4 , pp. 575-585
    • Fannjiang, Y.1    Kim, C.H.2    Huganir, R.L.3    Zou, S.4    Lindsten, T.5    Thompson, C.B.6
  • 30
    • 0036946518 scopus 로고    scopus 로고
    • Active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates are differentially expressed following systemic administration of kainic acid to the adult rat
    • Ferrer I, Blanco R, Carmona M, Puig B, Dominguez I, Vinals F (2002) Active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates are differentially expressed following systemic administration of kainic acid to the adult rat. Acta Neuropathol (Berlin) 103:391-407
    • (2002) Acta Neuropathol (Berlin) , vol.103 , pp. 391-407
    • Ferrer, I.1    Blanco, R.2    Carmona, M.3    Puig, B.4    Dominguez, I.5    Vinals, F.6
  • 32
    • 0027931560 scopus 로고
    • DNA fragmentation in rat brain after intraperitoneal administration of kainate
    • Filipkowski RK, Hetman M, Kaminska B, Kaczmarek L (1994) DNA fragmentation in rat brain after intraperitoneal administration of kainate. Neuroreport 5:1538-40
    • (1994) Neuroreport , vol.5 , pp. 1538-1540
    • Filipkowski, R.K.1    Hetman, M.2    Kaminska, B.3    Kaczmarek, L.4
  • 33
    • 0037371071 scopus 로고    scopus 로고
    • Hippocampal sclerosis is a progressive disorder: A longitudinal volumetric MRI study
    • Fuerst D, Shah J, Shah A, Watson C (2003) Hippocampal sclerosis is a progressive disorder: a longitudinal volumetric MRI study. Ann Neurol 53:413-6
    • (2003) Ann Neurol , vol.53 , pp. 413-416
    • Fuerst, D.1    Shah, J.2    Shah, A.3    Watson, C.4
  • 34
    • 0036789084 scopus 로고    scopus 로고
    • Caspase-3 is not activated in seizure-induced neuronal necrosis with internucleosomal DNA cleavage
    • Fujikawa DG, Ke X, Trinidad RB, Shinmei SS, Wu A (2002) Caspase-3 is not activated in seizure-induced neuronal necrosis with internucleosomal DNA cleavage. J Neurochem 83:229-40
    • (2002) J Neurochem , vol.83 , pp. 229-240
    • Fujikawa, D.G.1    Ke, X.2    Trinidad, R.B.3    Shinmei, S.S.4    Wu, A.5
  • 35
    • 0034085349 scopus 로고    scopus 로고
    • Kainic acid-induced seizures produce necrotic, not apoptotic, neurons with internucleosomal DNA cleavage: Implications for programmed cell death mechanisms
    • Fujikawa DG, Shinmei SS, Cai B (2000a) Kainic acid-induced seizures produce necrotic, not apoptotic, neurons with internucleosomal DNA cleavage: implications for programmed cell death mechanisms. Neuroscience 98:41-53
    • (2000) Neuroscience , vol.98 , pp. 41-53
    • Fujikawa, D.G.1    Shinmei, S.S.2    Cai, B.3
  • 36
    • 0033811496 scopus 로고    scopus 로고
    • Seizure-induced neuronal necrosis: Implications for programmed cell death mechanisms
    • Fujikawa DG, Shinmei SS, Cai B (2000b) Seizure-induced neuronal necrosis: implications for programmed cell death mechanisms. Epilepsia 41:S9-13
    • (2000) Epilepsia , vol.41
    • Fujikawa, D.G.1    Shinmei, S.S.2    Cai, B.3
  • 37
    • 0031798012 scopus 로고    scopus 로고
    • Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor
    • Gary DS, Bruce-Keller AJ, Kindy MS, Mattson MP (1998) Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor. J Cereb Blood Flow Metab 18:1283-7
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 1283-1287
    • Gary, D.S.1    Bruce-Keller, A.J.2    Kindy, M.S.3    Mattson, M.P.4
  • 38
    • 0033617402 scopus 로고    scopus 로고
    • Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic a beta peptide formation
    • Gervais FG, Xu D, Robertson GS, Vaillancourt JP, Zhu Y, Huang J et al (1999) Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation. Cell 97:395-406
    • (1999) Cell , vol.97 , pp. 395-406
    • Gervais, F.G.1    Xu, D.2    Robertson, G.S.3    Vaillancourt, J.P.4    Zhu, Y.5    Huang, J.6
  • 40
    • 0029001403 scopus 로고
    • Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain
    • Gillardon F, Wickert H, Zimmermann M (1995) Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain. Neurosci Lett 192:85-8
    • (1995) Neurosci Lett , vol.192 , pp. 85-88
    • Gillardon, F.1    Wickert, H.2    Zimmermann, M.3
  • 42
    • 0029982245 scopus 로고    scopus 로고
    • Expression of the proto-oncogene bcl-2 is increased in the rat brain following kainate-induced seizures
    • Graham SH, Chen J, Stetler RA, Zhu RL, Jin KL, Simon RP (1996) Expression of the proto-oncogene bcl-2 is increased in the rat brain following kainate-induced seizures. Rest Neurol Neurosci 9:243-50
    • (1996) Rest Neurol Neurosci , vol.9 , pp. 243-250
    • Graham, S.H.1    Chen, J.2    Stetler, R.A.3    Zhu, R.L.4    Jin, K.L.5    Simon, R.P.6
  • 43
    • 0021278632 scopus 로고
    • Status epilepticus: The reversibility of calcium loading and acute neuronal pathological changes in the rat hippocampus
    • Griffiths T, Evans MC, Meldrum BS (1984) Status epilepticus: the reversibility of calcium loading and acute neuronal pathological changes in the rat hippocampus. Neuroscience 12:557-67
    • (1984) Neuroscience , vol.12 , pp. 557-567
    • Griffiths, T.1    Evans, M.C.2    Meldrum, B.S.3
  • 44
    • 0035313071 scopus 로고    scopus 로고
    • Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis
    • Hartmann A, Troadec JD, Hunot S, Kikly K, Faucheux BA, Mouatt-Prigent A et al (2001) Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis. J Neurosci 21:2247-55
    • (2001) J Neurosci , vol.21 , pp. 2247-2255
    • Hartmann, A.1    Troadec, J.D.2    Hunot, S.3    Kikly, K.4    Faucheux, B.A.5    Mouatt-Prigent, A.6
  • 45
    • 0030824575 scopus 로고    scopus 로고
    • Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl- 2
    • He H, Lam M, McCormick TS, Distelhorst CW (1997) Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl- 2. J Cell Biol 138:1219-28
    • (1997) J Cell Biol , vol.138 , pp. 1219-1228
    • He, H.1    Lam, M.2    McCormick, T.S.3    Distelhorst, C.W.4
  • 46
    • 0141484571 scopus 로고    scopus 로고
    • Chronic epilepsy and cognition: A longitudinal study in temporal lobe epilepsy
    • Helmstaedter C, Kurthen M, Lux S, Reuber M, Elger CE (2003) Chronic epilepsy and cognition: a longitudinal study in temporal lobe epilepsy. Ann Neurol 54:425-32
    • (2003) Ann Neurol , vol.54 , pp. 425-432
    • Helmstaedter, C.1    Kurthen, M.2    Lux, S.3    Reuber, M.4    Elger, C.E.5
  • 47
    • 0026582702 scopus 로고
    • Caenorhabditis elegans gene ced-9 protects cells from programmed cell death
    • Hengartner MO, Ellis RE, Horvitz HR (1992) Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature 356:494-9
    • (1992) Nature , vol.356 , pp. 494-499
    • Hengartner, M.O.1    Ellis, R.E.2    Horvitz, H.R.3
  • 48
    • 0028288277 scopus 로고
    • C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
    • Hengartner MO, Horvitz HR (1994) C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 76:665-76
    • (1994) Cell , vol.76 , pp. 665-676
    • Hengartner, M.O.1    Horvitz, H.R.2
  • 49
    • 0036813472 scopus 로고    scopus 로고
    • Activation of Bcl-2-associated death protein and counter-response of Akt within cell populations during seizure-induced neuronal death
    • Henshall DC, Araki T, Schindler CK, Lan J-Q, Tiekoter K, Taki W et al (2002a) Activation of Bcl-2-associated death protein and counter-response of Akt within cell populations during seizure-induced neuronal death. J Neurosci 22:8458-65
    • (2002) J Neurosci , vol.22 , pp. 8458-8465
    • Henshall, D.C.1    Araki, T.2    Schindler, C.K.3    Lan, J.-Q.4    Tiekoter, K.5    Taki, W.6
  • 50
    • 0041430624 scopus 로고    scopus 로고
    • Expression of death-associated protein kinase and recruitment to the tumor necrosis factor signaling pathway following brief seizures
    • Henshall DC, Araki T, Schindler CK, Shinoda S, Lan J-Q, Simon RP (2003) Expression of death-associated protein kinase and recruitment to the tumor necrosis factor signaling pathway following brief seizures. J Neurochem 86:1260-70
    • (2003) J Neurochem , vol.86 , pp. 1260-1270
    • Henshall, D.C.1    Araki, T.2    Schindler, C.K.3    Shinoda, S.4    Lan, J.-Q.5    Simon, R.P.6
  • 51
    • 0035670146 scopus 로고    scopus 로고
    • Formation of the Apaf-1/ cytochrome c complex precedes activation of caspase-9 during seizure-induced neuronal death
    • Henshall DC, Bonislawski DP, Skradski SL, Araki T, Lan J-Q, Schindler CK et al (2001a) Formation of the Apaf-1/ cytochrome c complex precedes activation of caspase-9 during seizure-induced neuronal death. Cell Death Differ 8:1169-81
    • (2001) Cell Death Differ , vol.8 , pp. 1169-1181
    • Henshall, D.C.1    Bonislawski, D.P.2    Skradski, S.L.3    Araki, T.4    Lan, J.-Q.5    Schindler, C.K.6
  • 53
    • 0033974548 scopus 로고    scopus 로고
    • Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures
    • Henshall DC, Chen J, Simon RP (2000a) Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures. J Neurochem 74:1215-23
    • (2000) J Neurochem , vol.74 , pp. 1215-1223
    • Henshall, D.C.1    Chen, J.2    Simon, R.P.3
  • 54
    • 0033854412 scopus 로고    scopus 로고
    • Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy
    • Henshall DC, Clark RS, Adelson PD, Chen M, Watkins SC, Simon RP (2000b) Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy. Neurology 55:250-7
    • (2000) Neurology , vol.55 , pp. 250-257
    • Henshall, D.C.1    Clark, R.S.2    Adelson, P.D.3    Chen, M.4    Watkins, S.C.5    Simon, R.P.6
  • 56
    • 0034628960 scopus 로고    scopus 로고
    • Spatio-temporal profile of DNA fragmentation and its relationship to patterns of epileptiform activity following focally evoked limbic seizures
    • Henshall DC, Sinclair J, Simon RP (2000c) Spatio-temporal profile of DNA fragmentation and its relationship to patterns of epileptiform activity following focally evoked limbic seizures. Brain Res 858:290-302
    • (2000) Brain Res , vol.858 , pp. 290-302
    • Henshall, D.C.1    Sinclair, J.2    Simon, R.P.3
  • 58
    • 0035877265 scopus 로고    scopus 로고
    • Increased Bcl-w expression following focally evoked limbic seizures in the rat
    • Henshall DC, Skradski SL, Lan J, Ren T, Simon RP (2001d) Increased Bcl-w expression following focally evoked limbic seizures in the rat. Neurosci Lett 305:153-6
    • (2001) Neurosci Lett , vol.305 , pp. 153-156
    • Henshall, D.C.1    Skradski, S.L.2    Lan, J.3    Ren, T.4    Simon, R.P.5
  • 59
    • 0036077250 scopus 로고    scopus 로고
    • Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures
    • Henshall DC, Skradski SL, Meller R, Araki T, Minami M, Schindler CK et al (2002b) Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures. Neurobiol Dis 10:71-87
    • (2002) Neurobiol Dis , vol.10 , pp. 71-87
    • Henshall, D.C.1    Skradski, S.L.2    Meller, R.3    Araki, T.4    Minami, M.5    Schindler, C.K.6
  • 60
    • 0348038755 scopus 로고    scopus 로고
    • Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1)
    • Houseweart MK, Vilaythong A, Yin XM, Turk B, Noebels JL, Myers RM (2003) Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1). Cell Death Differ 10:1329-35
    • (2003) Cell Death Differ , vol.10 , pp. 1329-1335
    • Houseweart, M.K.1    Vilaythong, A.2    Yin, X.M.3    Turk, B.4    Noebels, J.L.5    Myers, R.M.6
  • 61
    • 0842303222 scopus 로고    scopus 로고
    • Expression of B/K protein in the hippocampus of kainate-induced rat seizure model
    • Jang YS, Lee MY, Choi SH, Kim MY, Chin H, Jeong SW et al (2004) Expression of B/K protein in the hippocampus of kainate-induced rat seizure model. Brain Res 999:203-11
    • (2004) Brain Res , vol.999 , pp. 203-211
    • Jang, Y.S.1    Lee, M.Y.2    Choi, S.H.3    Kim, M.Y.4    Chin, H.5    Jeong, S.W.6
  • 62
    • 0035211890 scopus 로고    scopus 로고
    • The role of cytokines and growth factors in seizures and their sequelae
    • Jankowsky JL, Patterson PH (2001) The role of cytokines and growth factors in seizures and their sequelae. Prog Neurobiol 63:125-49
    • (2001) Prog Neurobiol , vol.63 , pp. 125-149
    • Jankowsky, J.L.1    Patterson, P.H.2
  • 63
    • 0032714916 scopus 로고    scopus 로고
    • Bilateral reductions of hippocampal volume, glucose metabolism, and wada hemispheric memory performance are related to the duration of mesial temporal lobe epilepsy
    • Jokeit H, Ebner A, Arnold S, Schuller M, Antke C, Huang Y et al (1999) Bilateral reductions of hippocampal volume, glucose metabolism, and wada hemispheric memory performance are related to the duration of mesial temporal lobe epilepsy. J Neurol 246:926-33
    • (1999) J Neurol , vol.246 , pp. 926-933
    • Jokeit, H.1    Ebner, A.2    Arnold, S.3    Schuller, M.4    Antke, C.5    Huang, Y.6
  • 66
    • 0035184001 scopus 로고    scopus 로고
    • Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity
    • Kitao Y, Ozawa K, Miyazaki M, Tamatani M, Kobayashi T, Yanagi H et al (2001) Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity. J Clin Invest 108:1439-50
    • (2001) J Clin Invest , vol.108 , pp. 1439-1450
    • Kitao, Y.1    Ozawa, K.2    Miyazaki, M.3    Tamatani, M.4    Kobayashi, T.5    Yanagi, H.6
  • 67
    • 4944256085 scopus 로고    scopus 로고
    • Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injury
    • Knoblach SM, Alroy DA, Nikolaeva M, Cernak I, Stoica BA, Faden AI (2004) Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injury. J Cereb Blood Flow Metab 24:1119-32
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 1119-1132
    • Knoblach, S.M.1    Alroy, D.A.2    Nikolaeva, M.3    Cernak, I.4    Stoica, B.A.5    Faden, A.I.6
  • 68
    • 0033965979 scopus 로고    scopus 로고
    • Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus
    • Kondratyev A, Gale K (2000) Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus. Brain Res Mol Brain Res 75:216-24
    • (2000) Brain Res Mol Brain Res , vol.75 , pp. 216-224
    • Kondratyev, A.1    Gale, K.2
  • 69
    • 1242351327 scopus 로고    scopus 로고
    • Latency to onset of status epilepticus determines molecular mechanisms of seizure-induced cell death
    • Kondratyev A, Gale K (2004) Latency to onset of status epilepticus determines molecular mechanisms of seizure-induced cell death. Brain Res Mol Brain Res 121:86-94
    • (2004) Brain Res Mol Brain Res , vol.121 , pp. 86-94
    • Kondratyev, A.1    Gale, K.2
  • 70
    • 0035854536 scopus 로고    scopus 로고
    • Electroconvulsive shock exposure prevents neuronal apoptosis after kainic acid-evoked status epilepticus
    • Kondratyev A, Sahibzada N, Gale K (2001) Electroconvulsive shock exposure prevents neuronal apoptosis after kainic acid-evoked status epilepticus. Brain Res Mol Brain Res 91:1-13
    • (2001) Brain Res Mol Brain Res , vol.91 , pp. 1-13
    • Kondratyev, A.1    Sahibzada, N.2    Gale, K.3
  • 71
    • 0037154677 scopus 로고    scopus 로고
    • Status epilepticus leads to the degradation of the endogenous inhibitor of caspase-activated DNase in rats
    • Kondratyev A, Selby D, Gale K (2002) Status epilepticus leads to the degradation of the endogenous inhibitor of caspase-activated DNase in rats. Neurosci Lett 319:145-8
    • (2002) Neurosci Lett , vol.319 , pp. 145-148
    • Kondratyev, A.1    Selby, D.2    Gale, K.3
  • 72
    • 0035118969 scopus 로고    scopus 로고
    • Regulation of X-chromosome-linked inhibitor of apoptosis protein in kainic acid-induced neuronal death in the rat hippocampus
    • Korhonen L, Belluardo N, Lindholm D (2001) Regulation of X-chromosome-linked inhibitor of apoptosis protein in kainic acid-induced neuronal death in the rat hippocampus. Mol Cell Neurosci 17:364-72
    • (2001) Mol Cell Neurosci , vol.17 , pp. 364-372
    • Korhonen, L.1    Belluardo, N.2    Lindholm, D.3
  • 73
    • 0141836884 scopus 로고    scopus 로고
    • Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brain
    • Korhonen L, Belluardo N, Mudo G, Lindholm D (2003) Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brain. Eur J Neurosci 18:1121-34
    • (2003) Eur J Neurosci , vol.18 , pp. 1121-1134
    • Korhonen, L.1    Belluardo, N.2    Mudo, G.3    Lindholm, D.4
  • 74
    • 0036458341 scopus 로고    scopus 로고
    • Repeated brief seizures induce progressive hippocampal neuron loss and memory deficits
    • Kotloski R, Lynch M, Lauersdorf S, Sutula T (2002) Repeated brief seizures induce progressive hippocampal neuron loss and memory deficits. Prog Brain Res 135:95-110
    • (2002) Prog Brain Res , vol.135 , pp. 95-110
    • Kotloski, R.1    Lynch, M.2    Lauersdorf, S.3    Sutula, T.4
  • 76
    • 0033551738 scopus 로고    scopus 로고
    • Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease
    • LeBlanc A, Liu H, Goodyer C, Bergeron C, Hammond J (1999) Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease. J Biol Chem 274:23426-36
    • (1999) J Biol Chem , vol.274 , pp. 23426-23436
    • LeBlanc, A.1    Liu, H.2    Goodyer, C.3    Bergeron, C.4    Hammond, J.5
  • 77
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES et al (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479-89
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6
  • 78
    • 3142694436 scopus 로고    scopus 로고
    • The expression of Smac and XIAP in rat hippocampus following limbic seizure induced by kainic acid injection into amygdaloid nucleus
    • Li TF, Luo YM, Lu CZ (2004) The expression of Smac and XIAP in rat hippocampus following limbic seizure induced by kainic acid injection into amygdaloid nucleus]. Sheng Li Xue Bao 56:172-7
    • (2004) Sheng Li Xue Bao , vol.56 , pp. 172-177
    • Li, T.F.1    Luo, Y.M.2    Lu, C.Z.3
  • 79
    • 0037307212 scopus 로고    scopus 로고
    • To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: A review on the stress-activated signaling pathways and apoptotic pathways
    • Liou AKF, Clark RS, Henshall DC, Yin XM, Chen J (2003) To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways. Prog Neurobiol 69:103-42
    • (2003) Prog Neurobiol , vol.69 , pp. 103-142
    • Liou, A.K.F.1    Clark, R.S.2    Henshall, D.C.3    Yin, X.M.4    Chen, J.5
  • 80
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu X, Kim CN, Yang J, Jemmerson R, Wang X (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147-57
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 81
    • 0344915157 scopus 로고    scopus 로고
    • Bcl-2, Bax and Bcl-x expression following kainic acid administration at convulsant doses in the rat
    • Lopez E, Pozas E, Rivera R, Ferrer I (1999) Bcl-2, Bax and Bcl-x expression following kainic acid administration at convulsant doses in the rat. Neuroscience 91:1461-70
    • (1999) Neuroscience , vol.91 , pp. 1461-1470
    • Lopez, E.1    Pozas, E.2    Rivera, R.3    Ferrer, I.4
  • 83
    • 0033562658 scopus 로고    scopus 로고
    • CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis- inducing ligand mediate ischemia-induced apoptosis in neurons
    • Martin-Villalba A, Herr I, Jeremias I, Hahne M, Brandt R, Vogel J et al (1999) CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis- inducing ligand mediate ischemia-induced apoptosis in neurons. J Neurosci 19:3809-17
    • (1999) J Neurosci , vol.19 , pp. 3809-3817
    • Martin-Villalba, A.1    Herr, I.2    Jeremias, I.3    Hahne, M.4    Brandt, R.5    Vogel, J.6
  • 85
    • 0036019933 scopus 로고    scopus 로고
    • Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: Advanced findings from ASK1 knockout mice
    • Matsuzawa A, Nishitoh H, Tobiume K, Takeda K, Ichijo H (2002) Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice. Antioxid Redox Signal 4:415-25
    • (2002) Antioxid Redox Signal , vol.4 , pp. 415-425
    • Matsuzawa, A.1    Nishitoh, H.2    Tobiume, K.3    Takeda, K.4    Ichijo, H.5
  • 87
    • 0002350957 scopus 로고
    • Epilepsy
    • (Adams JH, Duchen LW, eds), New York: Oxford University Press
    • Meldrum BS, Bruton CJ (1992) Epilepsy. In: Greenfield's neuropathology (Adams JH, Duchen LW, eds), New York: Oxford University Press, 1246-83
    • (1992) Greenfield's Neuropathology , pp. 1246-1283
    • Meldrum, B.S.1    Bruton, C.J.2
  • 88
    • 0038823552 scopus 로고    scopus 로고
    • Seizure-like activity leads to the release of BAD from 14-3-3 protein and cell death in hippocampal neurons in vitro
    • Meller R, Schindler CK, Chu XP, Xiong ZG, Cameron JA, Simon RP et al (2003) Seizure-like activity leads to the release of BAD from 14-3-3 protein and cell death in hippocampal neurons in vitro. Cell Death Differ 10:539-47
    • (2003) Cell Death Differ , vol.10 , pp. 539-547
    • Meller, R.1    Schindler, C.K.2    Chu, X.P.3    Xiong, Z.G.4    Cameron, J.A.5    Simon, R.P.6
  • 89
    • 0041853690 scopus 로고    scopus 로고
    • Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    • Micheau O, Tschopp J (2003) Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114:181-90
    • (2003) Cell , vol.114 , pp. 181-190
    • Micheau, O.1    Tschopp, J.2
  • 90
    • 0037345852 scopus 로고    scopus 로고
    • Hippocampal programmed cell death after status epilepticus: Evidence for NMDA-receptor and ceramide-mediated mechanisms
    • Mikati MA, Abi-Habib RJ, El Sabban ME, Dbaibo GS, Kurdi RM, Kobeissi M et al (2003) Hippocampal programmed cell death after status epilepticus: evidence for NMDA-receptor and ceramide-mediated mechanisms. Epilepsia 44:282-91
    • (2003) Epilepsia , vol.44 , pp. 282-291
    • Mikati, M.A.1    Abi-Habib, R.J.2    El Sabban, M.E.3    Dbaibo, G.S.4    Kurdi, R.M.5    Kobeissi, M.6
  • 91
    • 15844417346 scopus 로고    scopus 로고
    • Neuronal activity increases the phosphorylation of the transcription factor cAMP response element-binding protein (CREB) in rat hippocampus and cortex
    • Moore AN, Waxham MN, Dash PK (1996) Neuronal activity increases the phosphorylation of the transcription factor cAMP response element-binding protein (CREB) in rat hippocampus and cortex. J Biol Chem 271:14214-20
    • (1996) J Biol Chem , vol.271 , pp. 14214-14220
    • Moore, A.N.1    Waxham, M.N.2    Dash, P.K.3
  • 92
    • 0031836346 scopus 로고    scopus 로고
    • An immunosuppressant, FK506, protects against neuronal dysfunction and death but has no effect on electrographic and behavioral activities induced by systemic kainate
    • Moriwaki A, Lu YF, Tomizawa K, Matsui H (1998) An immunosuppressant, FK506, protects against neuronal dysfunction and death but has no effect on electrographic and behavioral activities induced by systemic kainate. Neuroscience 86:855-65
    • (1998) Neuroscience , vol.86 , pp. 855-865
    • Moriwaki, A.1    Lu, Y.F.2    Tomizawa, K.3    Matsui, H.4
  • 94
    • 4344572376 scopus 로고    scopus 로고
    • Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation
    • Murphy BM, Creagh EM, Martin SJ (2004) Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation. J Biol Chem 279:36916-22
    • (2004) J Biol Chem , vol.279 , pp. 36916-36922
    • Murphy, B.M.1    Creagh, E.M.2    Martin, S.J.3
  • 95
    • 0031779334 scopus 로고    scopus 로고
    • Neuronal cyclin expression in the hippocampus in temporal lobe epilepsy
    • Nagy Z, Esiri MM (1998) Neuronal cyclin expression in the hippocampus in temporal lobe epilepsy. Exp Neurol 150:240-7
    • (1998) Exp Neurol , vol.150 , pp. 240-247
    • Nagy, Z.1    Esiri, M.M.2
  • 96
    • 0034698878 scopus 로고    scopus 로고
    • Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
    • Nakagawa T, Yuan J (2000) Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 150:887-94
    • (2000) J Cell Biol , vol.150 , pp. 887-894
    • Nakagawa, T.1    Yuan, J.2
  • 97
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
    • Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA et al (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403:98-103
    • (2000) Nature , vol.403 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6
  • 98
    • 0038368825 scopus 로고    scopus 로고
    • Administration of caspase 3 inhibitor during and after status epilepticus in rat: Effect on neuronal damage and epileptogenesis
    • Narkilahti S, Nissinen J, Pitkanen A (2003a) Administration of caspase 3 inhibitor during and after status epilepticus in rat: effect on neuronal damage and epileptogenesis. Neuropharmacology 44:1068-88
    • (2003) Neuropharmacology , vol.44 , pp. 1068-1088
    • Narkilahti, S.1    Nissinen, J.2    Pitkanen, A.3
  • 100
    • 14644399264 scopus 로고    scopus 로고
    • Caspase 6 expression in the rat hippocampus during epileptogenesis and epilepsy
    • Narkilahti S, Pitkanen A (2005) Caspase 6 expression in the rat hippocampus during epileptogenesis and epilepsy. Neuroscience 131:887-97
    • (2005) Neuroscience , vol.131 , pp. 887-897
    • Narkilahti, S.1    Pitkanen, A.2
  • 101
    • 0346877587 scopus 로고    scopus 로고
    • Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores
    • Nutt LK, Pataer A, Pahler J, Fang B, Roth J, McConkey DJ et al (2001) Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores. J Biol Chem 6:6
    • (2001) J Biol Chem , vol.6 , pp. 6
    • Nutt, L.K.1    Pataer, A.2    Pahler, J.3    Fang, B.4    Roth, J.5    McConkey, D.J.6
  • 102
    • 0036024020 scopus 로고    scopus 로고
    • Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9
    • O'Reilly LA, Ekert P, Harvey N, Marsden V, Cullen L, Vaux DL et al (2002) Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9. Cell Death Differ 9:832-41
    • (2002) Cell Death Differ , vol.9 , pp. 832-841
    • O'Reilly, L.A.1    Ekert, P.2    Harvey, N.3    Marsden, V.4    Cullen, L.5    Vaux, D.L.6
  • 104
    • 0030907041 scopus 로고    scopus 로고
    • Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus
    • Parent JM, Yu TW, Leibowitz RT, Geschwind DH, Sloviter RS, Lowenstein DH (1997) Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J Neurosci 17:3727-38
    • (1997) J Neurosci , vol.17 , pp. 3727-3738
    • Parent, J.M.1    Yu, T.W.2    Leibowitz, R.T.3    Geschwind, D.H.4    Sloviter, R.S.5    Lowenstein, D.H.6
  • 105
    • 0043037253 scopus 로고    scopus 로고
    • Endoplasmic reticulum: A primary target in various acute disorders and degenerative diseases of the brain
    • Paschen W (2003) Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain. Cell Calcium 34:365-83
    • (2003) Cell Calcium , vol.34 , pp. 365-383
    • Paschen, W.1
  • 106
    • 0032588215 scopus 로고    scopus 로고
    • Seizure-induced cell death produced by repeated tetanic stimulation in vitro: Possible role of endoplasmic reticulum calcium stores
    • Pelletier MR, Wadia JS, Mills LR, Carlen PL (1999) Seizure-induced cell death produced by repeated tetanic stimulation in vitro: possible role of endoplasmic reticulum calcium stores. J Neurophysiol 81:3054-64
    • (1999) J Neurophysiol , vol.81 , pp. 3054-3064
    • Pelletier, M.R.1    Wadia, J.S.2    Mills, L.R.3    Carlen, P.L.4
  • 107
    • 0035355341 scopus 로고    scopus 로고
    • The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: Significance for the molecular mechanism of Bcl-2 action
    • Pinton P, Ferrari D, Rapizzi E, Di Virgilio FD, Pozzan T, Rizzuto R (2001) The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action. EMBO J 20:2690-701
    • (2001) EMBO J , vol.20 , pp. 2690-2701
    • Pinton, P.1    Ferrari, D.2    Rapizzi, E.3    Di Virgilio, F.D.4    Pozzan, T.5    Rizzuto, R.6
  • 109
    • 14844328621 scopus 로고    scopus 로고
    • Calpain I induces cleavage and release of apoptosis inducing factor from isolated mitochondria
    • Polster BM, Etxebarria A, Basanez G, Hardwick JM, Nicholls DG (2004) Calpain I induces cleavage and release of apoptosis inducing factor from isolated mitochondria. J Biol Chem 280:6447-54
    • (2004) J Biol Chem , vol.280 , pp. 6447-6454
    • Polster, B.M.1    Etxebarria, A.2    Basanez, G.3    Hardwick, J.M.4    Nicholls, D.G.5
  • 110
    • 4544298249 scopus 로고    scopus 로고
    • Mitochondrial mechanisms of neural cell apoptosis
    • Polster BM, Fiskum G (2004) Mitochondrial mechanisms of neural cell apoptosis. J Neurochem 90:1281-9
    • (2004) J Neurochem , vol.90 , pp. 1281-1289
    • Polster, B.M.1    Fiskum, G.2
  • 111
    • 0037155546 scopus 로고    scopus 로고
    • Caspase-3-associated apoptotic cell death in excitotoxic necrosis of the entorhinal cortex following intraperitoneal injection of kainic acid in the rat
    • Puig B, Ferrer I (2002) Caspase-3-associated apoptotic cell death in excitotoxic necrosis of the entorhinal cortex following intraperitoneal injection of kainic acid in the rat. Neurosci Lett 321:182-6
    • (2002) Neurosci Lett , vol.321 , pp. 182-186
    • Puig, B.1    Ferrer, I.2
  • 112
    • 0033542482 scopus 로고    scopus 로고
    • Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
    • Qin H, Srinivasula SM, Wu G, Fernandes-Alnemri T, Alnemri ES, Shi Y (1999) Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature 399:549-57
    • (1999) Nature , vol.399 , pp. 549-557
    • Qin, H.1    Srinivasula, S.M.2    Wu, G.3    Fernandes-Alnemri, T.4    Alnemri, E.S.5    Shi, Y.6
  • 113
    • 0035823579 scopus 로고    scopus 로고
    • Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation
    • Rao RV, Hermel E, Castro-Obregon S, del Rio G, Ellerby LM, Ellerby HM et al (2001) Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation. J Biol Chem 276:33869-74
    • (2001) J Biol Chem , vol.276 , pp. 33869-33874
    • Rao, R.V.1    Hermel, E.2    Castro-Obregon, S.3    Del Rio, G.4    Ellerby, L.M.5    Ellerby, H.M.6
  • 114
    • 0032511112 scopus 로고    scopus 로고
    • Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses
    • Rizzuto R, Pinton P, Carrington W, Fay FS, Fogarty KE, Lifshitz LM et al (1998) Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses. Science 280:1763-6
    • (1998) Science , vol.280 , pp. 1763-1766
    • Rizzuto, R.1    Pinton, P.2    Carrington, W.3    Fay, F.S.4    Fogarty, K.E.5    Lifshitz, L.M.6
  • 115
    • 0036184826 scopus 로고    scopus 로고
    • HSV-mediated delivery of virally derived anti-apoptotic genes protects the rat hippocampus from damage following excitotoxicity, but not metabolic disruption
    • Roy M, Hom JJ, Sapolsky RM (2002) HSV-mediated delivery of virally derived anti-apoptotic genes protects the rat hippocampus from damage following excitotoxicity, but not metabolic disruption. Gene Therapy 9:214-9
    • (2002) Gene Therapy , vol.9 , pp. 214-219
    • Roy, M.1    Hom, J.J.2    Sapolsky, R.M.3
  • 116
    • 0030698127 scopus 로고    scopus 로고
    • The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
    • Roy N, Deveraux QL, Takahashi R, Salvesen GS, Reed JC (1997) The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J 16:6914-25
    • (1997) EMBO J , vol.16 , pp. 6914-6925
    • Roy, N.1    Deveraux, Q.L.2    Takahashi, R.3    Salvesen, G.S.4    Reed, J.C.5
  • 117
    • 0031889132 scopus 로고    scopus 로고
    • Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
    • Sakahira H, Enari M, Nagata S (1998) Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391:96-9
    • (1998) Nature , vol.391 , pp. 96-99
    • Sakahira, H.1    Enari, M.2    Nagata, S.3
  • 118
    • 0036088471 scopus 로고    scopus 로고
    • IAP proteins: Blocking the road to death's door
    • Salvesen GS, Duckett CS (2002) IAP proteins: blocking the road to death's door. Nat Rev Mol Cell Biol 3:401-10
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 401-410
    • Salvesen, G.S.1    Duckett, C.S.2
  • 119
    • 0442323501 scopus 로고    scopus 로고
    • Subcellular distribution of Bcl-2 family proteins and 14-3-3 within the rat hippocampus during seizure-induced neuronal death in the rat
    • Schindler CK, Shinoda S, Simon RP, Henshall DC (2004) Subcellular distribution of Bcl-2 family proteins and 14-3-3 within the rat hippocampus during seizure-induced neuronal death in the rat. Neuroscience Lett 356:163-6
    • (2004) Neuroscience Lett , vol.356 , pp. 163-166
    • Schindler, C.K.1    Shinoda, S.2    Simon, R.P.3    Henshall, D.C.4
  • 121
    • 1842532300 scopus 로고    scopus 로고
    • Development of a model of seizure-induced hippocampal injury with features of programmed cell death in the BALB/c mouse
    • Shinoda S, Araki T, Lan JQ, Schindler CK, Simon RP, Taki W et al (2004a) Development of a model of seizure-induced hippocampal injury with features of programmed cell death in the BALB/c mouse. J Neurosci Res 76:121-8
    • (2004) J Neurosci Res , vol.76 , pp. 121-128
    • Shinoda, S.1    Araki, T.2    Lan, J.Q.3    Schindler, C.K.4    Simon, R.P.5    Taki, W.6
  • 123
    • 11144355911 scopus 로고    scopus 로고
    • Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy
    • Shinoda S, Schindler CK, Meller R, So NK, Araki T, Yamamoto A et al (2004b) Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy. J Clin Invest 113:1059-68
    • (2004) J Clin Invest , vol.113 , pp. 1059-1068
    • Shinoda, S.1    Schindler, C.K.2    Meller, R.3    So, N.K.4    Araki, T.5    Yamamoto, A.6
  • 124
    • 0037795559 scopus 로고    scopus 로고
    • Formation of a tumour necrosis factor receptor 1 molecular scaffolding complex and activation of apoptosis signal-regulating kinase 1 during seizure-induced neuronal death
    • Shinoda S, Skradski SL, Araki T, Schindler CK, Meller R, Lan J-Q et al (2003b) Formation of a tumour necrosis factor receptor 1 molecular scaffolding complex and activation of apoptosis signal-regulating kinase 1 during seizure-induced neuronal death. Eur J Neurosci 17:2065-76
    • (2003) Eur J Neurosci , vol.17 , pp. 2065-2076
    • Shinoda, S.1    Skradski, S.L.2    Araki, T.3    Schindler, C.K.4    Meller, R.5    Lan, J.-Q.6
  • 127
    • 0037154781 scopus 로고    scopus 로고
    • Differential induction of p53 in immature and adult rat brain following lithium-pilocarpine status epilepticus
    • Tan Z, Sankar R, Shin D, Sun N, Liu H, Wasterlain CG et al (2002) Differential induction of p53 in immature and adult rat brain following lithium-pilocarpine status epilepticus. Brain Res 928:187-93
    • (2002) Brain Res , vol.928 , pp. 187-193
    • Tan, Z.1    Sankar, R.2    Shin, D.3    Sun, N.4    Liu, H.5    Wasterlain, C.G.6
  • 128
    • 0032933248 scopus 로고    scopus 로고
    • Neuroimaging evidence of progressive neuronal loss and dysfunction in temporal lobe epilepsy
    • Tasch E, Cendes F, Li LM, Dubeau F, Andermann F, Arnold DL (1999) Neuroimaging evidence of progressive neuronal loss and dysfunction in temporal lobe epilepsy. Ann Neurol 45:568-76
    • (1999) Ann Neurol , vol.45 , pp. 568-576
    • Tasch, E.1    Cendes, F.2    Li, L.M.3    Dubeau, F.4    Andermann, F.5    Arnold, D.L.6
  • 129
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA, Lazebnik Y (1998) Caspases: enemies within. Science 281:1312-6
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 130
    • 0037121812 scopus 로고    scopus 로고
    • In vivo role of caspases in excitotoxic neuronal death: Generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons
    • Tomioka M, Shirotani K, Iwata N, Lee HJ, Yang F, Cole GM et al (2002) In vivo role of caspases in excitotoxic neuronal death: generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons. Brain Res Mol Brain Res 108:18-32
    • (2002) Brain Res Mol Brain Res , vol.108 , pp. 18-32
    • Tomioka, M.1    Shirotani, K.2    Iwata, N.3    Lee, H.J.4    Yang, F.5    Cole, G.M.6
  • 131
    • 0037072873 scopus 로고    scopus 로고
    • Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases
    • Troy CM, Friedman JE, Friedman WJ (2002) Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases. J Biol Chem 277:34295-302
    • (2002) J Biol Chem , vol.277 , pp. 34295-34302
    • Troy, C.M.1    Friedman, J.E.2    Friedman, W.J.3
  • 133
    • 0034616942 scopus 로고    scopus 로고
    • Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
    • Verhagen AM, Ekert PG, Pakusch M, Silke J, Connolly LM, Reid GE et al (2000) Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102:43-53
    • (2000) Cell , vol.102 , pp. 43-53
    • Verhagen, A.M.1    Ekert, P.G.2    Pakusch, M.3    Silke, J.4    Connolly, L.M.5    Reid, G.E.6
  • 134
    • 0034051665 scopus 로고    scopus 로고
    • Transgenic mice neuronally expressing baculoviral p35 are resistant to diverse types of induced apoptosis, including seizure-associated neurodegeneration
    • Viswanath V, Wu Z, Fonck C, Wei Q, Boonplueang R, Andersen JK (2000) Transgenic mice neuronally expressing baculoviral p35 are resistant to diverse types of induced apoptosis, including seizure-associated neurodegeneration. Proc Natl Acad Sci USA 97:2270-5
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2270-2275
    • Viswanath, V.1    Wu, Z.2    Fonck, C.3    Wei, Q.4    Boonplueang, R.5    Andersen, J.K.6
  • 135
    • 0035957653 scopus 로고    scopus 로고
    • Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
    • Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ et al (2001) Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292:727-30
    • (2001) Science , vol.292 , pp. 727-730
    • Wei, M.C.1    Zong, W.X.2    Cheng, E.H.3    Lindsten, T.4    Panoutsakopoulou, V.5    Ross, A.J.6
  • 136
    • 14744289621 scopus 로고    scopus 로고
    • Expression time course and spatial distribution of activated caspase-3 after experimental status epilepticus: Contribution of delayed neuronal cell death to seizure-induced neuronal injury
    • Weise J, Engelhorn T, Dorfler A, Aker S, Bahr M, Hufnagel A (2005) Expression time course and spatial distribution of activated caspase-3 after experimental status epilepticus: contribution of delayed neuronal cell death to seizure-induced neuronal injury. Neurobiol Dis 18:582-90
    • (2005) Neurobiol Dis , vol.18 , pp. 582-590
    • Weise, J.1    Engelhorn, T.2    Dorfler, A.3    Aker, S.4    Bahr, M.5    Hufnagel, A.6
  • 137
  • 138
    • 0035957929 scopus 로고    scopus 로고
    • Activation of caspase-12, an endoplasmic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
    • Yoneda T, Imaizumi K, Oono K, Yui D, Gomi F, Katayama T et al (2001) Activation of caspase-12, an endoplasmic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J Biol Chem 276:13935-40
    • (2001) J Biol Chem , vol.276 , pp. 13935-13940
    • Yoneda, T.1    Imaizumi, K.2    Oono, K.3    Yui, D.4    Gomi, F.5    Katayama, T.6
  • 139
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
    • Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 75:641-52
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5
  • 140
    • 0032546387 scopus 로고    scopus 로고
    • Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/ Mort1
    • Zhang J, Cado D, Chen A, Kabra NH, Winoto A (1998a) Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/ Mort1. Nature 392:296-300
    • (1998) Nature , vol.392 , pp. 296-300
    • Zhang, J.1    Cado, D.2    Chen, A.3    Kabra, N.H.4    Winoto, A.5
  • 143
    • 0034668842 scopus 로고    scopus 로고
    • Selective and protracted apoptosis in human primary neurons microinjected with active caspase-3, -6, -7, and -8
    • Zhang Y, Goodyer C, LeBlanc A (2000) Selective and protracted apoptosis in human primary neurons microinjected with active caspase-3, -6, -7, and -8. J Neurosci 20:8384-9
    • (2000) J Neurosci , vol.20 , pp. 8384-8389
    • Zhang, Y.1    Goodyer, C.2    LeBlanc, A.3
  • 144
    • 0032799633 scopus 로고    scopus 로고
    • Caspases: Their intracellular localization and translocation during apoptosis
    • Zhivotovsky B, Samali A, Gahm A, Orrenius S (1999) Caspases: their intracellular localization and translocation during apoptosis. Cell Death Differ 6:644-51
    • (1999) Cell Death Differ , vol.6 , pp. 644-651
    • Zhivotovsky, B.1    Samali, A.2    Gahm, A.3    Orrenius, S.4


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